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Aliases for DNAJB3 Gene

Aliases for DNAJB3 Gene

  • DnaJ Heat Shock Protein Family (Hsp40) Member B3 2 3 5
  • DnaJ (Hsp40) Homolog, Subfamily B, Member 3 2 3
  • HCG3 3 4
  • DnaJ Homolog Subfamily B Member 3 3

External Ids for DNAJB3 Gene

Previous GeneCards Identifiers for DNAJB3 Gene

  • GC02U901524
  • GC02M234318
  • GC02M234651
  • GC02M226451

Summaries for DNAJB3 Gene

GeneCards Summary for DNAJB3 Gene

DNAJB3 (DnaJ Heat Shock Protein Family (Hsp40) Member B3) is a Protein Coding gene.

UniProtKB/Swiss-Prot for DNAJB3 Gene

  • May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins.

Additional gene information for DNAJB3 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJB3 Gene

Genomics for DNAJB3 Gene

Regulatory Elements for DNAJB3 Gene

Enhancers for DNAJB3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H233763 1 FANTOM5 ENCODE 5.3 -20.4 -20431 1.6 FOXA2 TAF1 MAX RAD21 YY1 ZFHX2 HNF4G MAFK EGR2 REST UGT1A4 UGT1A6 LOC100286922 DNAJB3 UGT1A1 MROH2A
GH02H233757 0.5 ENCODE 5.3 -14.5 -14468 1.8 NFYC PPARG MIXL1 UGT1A6 LOC100286922 USP40 DNAJB3 UGT1A1 PIR60361
GH02H233745 1 ENCODE 0.7 -1.6 -1570 1 FOXA2 ATF1 MLX ARID4B DMAP1 YY1 TCF12 ATF7 SP5 ZHX2 UGT1A6 DNAJB3 UGT1A2P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DNAJB3 on UCSC Golden Path with GeneCards custom track

Genomic Locations for DNAJB3 Gene

Genomic Locations for DNAJB3 Gene
1,266 bases
Minus strand

Genomic View for DNAJB3 Gene

Genes around DNAJB3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DNAJB3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DNAJB3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAJB3 Gene

Proteins for DNAJB3 Gene

  • Protein details for DNAJB3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    DnaJ homolog subfamily B member 3
    Protein Accession:

    Protein attributes for DNAJB3 Gene

    145 amino acids
    Molecular mass:
    16559 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for DNAJB3 Gene

neXtProt entry for DNAJB3 Gene

Post-translational modifications for DNAJB3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DNAJB3 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for DNAJB3 Gene

Domains & Families for DNAJB3 Gene

Gene Families for DNAJB3 Gene

Protein Domains for DNAJB3 Gene

Suggested Antigen Peptide Sequences for DNAJB3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DNAJB3: view

No data available for UniProtKB/Swiss-Prot for DNAJB3 Gene

Function for DNAJB3 Gene

Molecular function for DNAJB3 Gene

UniProtKB/Swiss-Prot Function:
May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins.

Phenotypes From GWAS Catalog for DNAJB3 Gene

genes like me logo Genes that share phenotypes with DNAJB3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DNAJB3 Gene

Localization for DNAJB3 Gene

Gene Ontology (GO) - Cellular Components for DNAJB3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with DNAJB3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for DNAJB3 Gene

Pathways & Interactions for DNAJB3 Gene

SuperPathways for DNAJB3 Gene

No Data Available

Interacting Proteins for DNAJB3 Gene

Selected Interacting proteins: Q8WWF6-DNJB3_HUMAN for DNAJB3 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for DNAJB3 Gene


No data available for Pathways by source and SIGNOR curated interactions for DNAJB3 Gene

Drugs & Compounds for DNAJB3 Gene

No Compound Related Data Available

Transcripts for DNAJB3 Gene

mRNA/cDNA for DNAJB3 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DNAJB3 Gene

DnaJ (Hsp40) homolog, subfamily B, member 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJB3 Gene

No ASD Table

Relevant External Links for DNAJB3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DNAJB3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DNAJB3 Gene

mRNA differential expression in normal tissues according to GTEx for DNAJB3 Gene

This gene is overexpressed in Testis (x47.6).

Protein differential expression in normal tissues from HIPED for DNAJB3 Gene

This gene is overexpressed in Heart (48.7) and Peripheral blood mononuclear cells (20.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for DNAJB3 Gene

Protein tissue co-expression partners for DNAJB3 Gene

NURSA nuclear receptor signaling pathways regulating expression of DNAJB3 Gene:


SOURCE GeneReport for Unigene cluster for DNAJB3 Gene:


mRNA Expression by UniProt/SwissProt for DNAJB3 Gene:

Tissue specificity: Expressed in sperm (at protein level).
genes like me logo Genes that share expression patterns with DNAJB3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DNAJB3 Gene

Orthologs for DNAJB3 Gene

Evolution for DNAJB3 Gene

Gene Tree for DNAJB3 (if available)
Gene Tree for DNAJB3 (if available)

No data available for Orthologs for DNAJB3 Gene

Paralogs for DNAJB3 Gene

(18) SIMAP similar genes for DNAJB3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with DNAJB3: view

No data available for Paralogs for DNAJB3 Gene

Variants for DNAJB3 Gene

Sequence variations from dbSNP and Humsavar for DNAJB3 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1002862654 -- 233,744,129(+) CTGTG(A/C)GGCCC intron-variant, upstream-variant-2KB
rs1002936325 -- 233,744,376(+) CAGTT(C/T)TCCAA intron-variant, upstream-variant-2KB
rs1003194784 -- 233,745,429(+) TTGTG(A/G)GGCAA intron-variant, upstream-variant-2KB
rs1003270220 -- 233,745,788(+) GGGGG(G/T)CTGGG intron-variant, upstream-variant-2KB
rs1003987688 -- 233,744,443(+) TACTG(C/T)ATTAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for DNAJB3 Gene

Variant ID Type Subtype PubMed ID
nsv519815 CNV loss 19592680
nsv514125 CNV loss 21397061
nsv498958 CNV loss 21111241
nsv433211 CNV loss 18776910
nsv3215 CNV deletion 18451855
nsv1013712 CNV loss 25217958
esv3594681 CNV gain 21293372
esv3594680 CNV loss 21293372
esv2760613 CNV loss 21179565
esv25622 CNV loss 19812545
esv2422005 CNV deletion 20811451
dgv769e199 CNV deletion 23128226

Relevant External Links for DNAJB3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DNAJB3 Gene

Disorders for DNAJB3 Gene

Relevant External Links for DNAJB3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for DNAJB3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DNAJB3 Gene

Publications for DNAJB3 Gene

  1. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M … Moll S (Journal of proteomics 2013) 3 60
  2. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y … Ge F (Molecular & cellular proteomics : MCP 2013) 3 60
  3. Identification of HYPK-interacting proteins reveals involvement of HYPK in regulating cell growth, cell cycle, unfolded protein response and cell death. (PMID: 23272104) Choudhury KR … Bhattacharyya NP (PloS one 2012) 3 60
  4. Structure of msj-1 gene in mice and humans: a possible role in the regulation of male reproduction. (PMID: 18184612) Meccariello R … Fasano S (General and comparative endocrinology 2008) 4 60
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3 60

Products for DNAJB3 Gene

Sources for DNAJB3 Gene

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