Aliases for DNAJB2 Gene
External Ids for DNAJB2 Gene
Previous HGNC Symbols for DNAJB2 Gene
Previous GeneCards Identifiers for DNAJB2 Gene
This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
GeneCards Summary for DNAJB2 Gene
DNAJB2 (DnaJ Heat Shock Protein Family (Hsp40) Member B2) is a Protein Coding gene. Diseases associated with DNAJB2 include Spinal Muscular Atrophy, Distal, Autosomal Recessive, 5 and Charcot-Marie-Tooth Disease, Axonal, Type 2T. Among its related pathways are Protein processing in endoplasmic reticulum. GO annotations related to this gene include unfolded protein binding and Hsp70 protein binding. An important paralog of this gene is DNAJB6.