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Aliases for DNAJB13 Gene

Aliases for DNAJB13 Gene

  • DnaJ (Hsp40) Homolog, Subfamily B, Member 13 2 3
  • TSARG6 3 4 6
  • Testis Spermatogenesis Apoptosis-Related Gene 3 Protein 3 4
  • Testis Spermatogenesis Apoptosis-Related Gene 6 Protein 3 4
  • Testis Spermatocyte Apoptosis-Related Gene 6 Protein 3 4
  • Testis And Spermatogenesis Cell-Related Protein 6 3 4
  • DnaJ (Hsp40) Related, Subfamily B, Member 13 2 3
  • Testis Spermatogenesis Apoptosis-Related Protein 6 3
  • Radial Spoke 16 Homolog A (Chlamydomonas) 2
  • DnaJ Homolog Subfamily B Member 13 3
  • Radial Spoke 16 Homolog A 3
  • DnaJ-Like Protein 3
  • RSPH16A 3
  • TSARG5 3
  • TSARG3 4

External Ids for DNAJB13 Gene

Summaries for DNAJB13 Gene

Entrez Gene Summary for DNAJB13 Gene

  • DNAJA13 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins. For background information on the DNAJ family, see 608375.[supplied by OMIM, Mar 2008]

GeneCards Summary for DNAJB13 Gene

DNAJB13 (DnaJ (Hsp40) Homolog, Subfamily B, Member 13) is a Protein Coding gene. GO annotations related to this gene include unfolded protein binding. An important paralog of this gene is DNAJB7.

UniProtKB/Swiss-Prot for DNAJB13 Gene

  • May be involved in inhibiting testis spermatogenesis apoptosis

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJB13 Gene

Genomics for DNAJB13 Gene

Genomic Location for DNAJB13 Gene

Start:
73,950,319 bp from pter
End:
73,970,668 bp from pter
Size:
20,350 bases
Orientation:
Plus strand

Genomic View for DNAJB13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DNAJB13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAJB13 Gene

Regulatory Elements for DNAJB13 Gene

Proteins for DNAJB13 Gene

  • Protein details for DNAJB13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P59910-DJB13_HUMAN
    Recommended name:
    DnaJ homolog subfamily B member 13
    Protein Accession:
    P59910
    Secondary Accessions:
    • B3LEP4
    • Q8IZW5

    Protein attributes for DNAJB13 Gene

    Size:
    316 amino acids
    Molecular mass:
    36118 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DNAJB13 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DNAJB13 Gene

Proteomics data for DNAJB13 Gene at MOPED

Post-translational modifications for DNAJB13 Gene

No Post-translational modifications

Other Protein References for DNAJB13 Gene

No data available for DME Specific Peptides for DNAJB13 Gene

Domains for DNAJB13 Gene

Gene Families for DNAJB13 Gene

HGNC:
  • DNAJ :Heat shock proteins / DNAJ (HSP40)

Protein Domains for DNAJB13 Gene

UniProtKB/Swiss-Prot:

DJB13_HUMAN
Domain:
  • Contains 1 J domain.:
    • P59910
genes like me logo Genes that share domains with DNAJB13: view

Function for DNAJB13 Gene

Molecular function for DNAJB13 Gene

UniProtKB/Swiss-Prot Function: May be involved in inhibiting testis spermatogenesis apoptosis

Gene Ontology (GO) - Molecular Function for DNAJB13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0051082 unfolded protein binding IEA --
genes like me logo Genes that share ontologies with DNAJB13: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DNAJB13 Gene

Localization for DNAJB13 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DNAJB13 Gene COMPARTMENTS Subcellular localization image for DNAJB13 gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 2

Gene Ontology (GO) - Cellular Components for DNAJB13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with DNAJB13: view

Pathways for DNAJB13 Gene

SuperPathways for DNAJB13 Gene

No Data Available

Interacting Proteins for DNAJB13 Gene

Gene Ontology (GO) - Biological Process for DNAJB13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006457 protein folding IEA --
genes like me logo Genes that share ontologies with DNAJB13: view

No data available for Pathways by source for DNAJB13 Gene

Transcripts for DNAJB13 Gene

Unigene Clusters for DNAJB13 Gene

DnaJ (Hsp40) homolog, subfamily B, member 13:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJB13 Gene

No ASD Table

Relevant External Links for DNAJB13 Gene

GeneLoc Exon Structure for
DNAJB13
ECgene alternative splicing isoforms for
DNAJB13

Expression for DNAJB13 Gene

mRNA expression in normal human tissues for DNAJB13 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for DNAJB13 Gene

This gene is overexpressed in Testis (10.3), Cervix - Endocervix (8.3), and Fallopian Tube (7.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for DNAJB13 Gene

SOURCE GeneReport for Unigene cluster for DNAJB13 Gene Hs.567888

mRNA Expression by UniProt/SwissProt for DNAJB13 Gene

P59910-DJB13_HUMAN
Tissue specificity: Specifically expressed in testis
genes like me logo Genes that share expressions with DNAJB13: view

Orthologs for DNAJB13 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DNAJB13 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia DNAJB13 36
  • 89.45 (n)
  • 92.09 (a)
DNAJB13 37
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DNAJB13 36
  • 89.87 (n)
  • 93.67 (a)
DNAJB13 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dnajb13 36
  • 86.81 (n)
  • 89.87 (a)
Dnajb13 16
Dnajb13 37
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DNAJB13 37
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DNAJB13 37
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dnajb13 36
  • 88.29 (n)
  • 91.46 (a)
chicken
(Gallus gallus)
Aves DNAJB13 36
  • 70.68 (n)
  • 69.3 (a)
DNAJB13 37
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DNAJB13 37
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia dnajb13 36
  • 68.78 (n)
  • 70.89 (a)
zebrafish
(Danio rerio)
Actinopterygii dnajb13 36
  • 62.13 (n)
  • 62.03 (a)
dnajb13 37
  • 61 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG12020 37
  • 31 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G08910 36
  • 52.97 (n)
  • 46.93 (a)
rice
(Oryza sativa)
Liliopsida Os02g0306900 36
  • 52.06 (n)
  • 47.73 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.14203 36
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 67 (a)
OneToOne
Species with no ortholog for DNAJB13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DNAJB13 Gene

ENSEMBL:
Gene Tree for DNAJB13 (if available)
TreeFam:
Gene Tree for DNAJB13 (if available)

Paralogs for DNAJB13 Gene

Selected SIMAP similar genes for DNAJB13 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with DNAJB13: view

Variants for DNAJB13 Gene

Sequence variations from dbSNP and Humsavar for DNAJB13 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs589295 -- 73,961,142(-) CCACC(A/G)TTCCT intron-variant
rs599277 -- 73,969,018(-) GGAGA(C/T)AGAAT intron-variant
rs603702 -- 73,962,035(-) CAGGC(A/G)GATCA intron-variant
rs605442 -- 73,962,395(-) TGCTC(A/G)TCTAT intron-variant
rs607640 -- 73,962,446(-) CATTC(A/G)TTTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DNAJB13 Gene

Variant ID Type Subtype PubMed ID
esv1001380 CNV Gain 20482838

Relevant External Links for DNAJB13 Gene

HapMap Linkage Disequilibrium report
DNAJB13

Disorders for DNAJB13 Gene

(1) University of Copenhagen DISEASES for DNAJB13 Gene

Relevant External Links for DNAJB13

Genetic Association Database (GAD)
DNAJB13
Human Genome Epidemiology (HuGE) Navigator
DNAJB13
genes like me logo Genes that share disorders with DNAJB13: view

No data available for UniProtKB/Swiss-Prot for DNAJB13 Gene

Publications for DNAJB13 Gene

  1. Molecular cloning of TSARG3 gene related to apoptosis in human spermatogenic cells. (PMID: 12673577) Liu G. … Li L. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2003) 3 4
  2. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PMID: 20677014) Shimada M. … Tokunaga K. (Hum. Genet. 2010) 3 49
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Molecular cloning of TSARG6 gene related to apoptosis in human spermatogenic cells. (PMID: 14970903) Liu G. … Xing X.W. (Acta Biochim. Biophys. Sin. (Shanghai) 2004) 3

Products for DNAJB13 Gene

Sources for DNAJB13 Gene

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