Aliases for DNAI2 Gene
External Ids for DNAI2 Gene
Previous GeneCards Identifiers for DNAI2 Gene
The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010]
GeneCards Summary for DNAI2 Gene
DNAI2 (Dynein, Axonemal, Intermediate Chain 2) is a Protein Coding gene. Diseases associated with DNAI2 include primary ciliary dyskinesia 9: dnai2-related primary ciliary dyskinesia and ciliary dyskinesia, primary, 9, with or without situs inversus. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include microtubule motor activity. An important paralog of this gene is WDR63.
UniProtKB/Swiss-Prot for DNAI2 Gene
Part of the dynein complex of respiratory cilia