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DNAH9 Gene

protein-coding   GIFtS: 58
GCID: GC17P011501

Dynein, Axonemal, Heavy Chain 9

(Previous names: dynein, axonemal, heavy polypeptide 17-like, dynein, axonemal,...)
(Previous symbol: DNAH17L)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dynein, Axonemal, Heavy Chain 91 2     HL-202
DNAH17L1 2 3 5     HL202
Dynein, Axonemal, Heavy Polypeptide 91 2     DNAH9 Variant Protein2
Axonemal Beta Dynein Heavy Chain 92 3     Dynein Heavy Chain 9, Axonemal2
Ciliary Dynein Heavy Chain 92 3     DNAL13
DNEL12 5     KIAA03573
Dynein, Axonemal, Heavy Polypeptide 17-Like1     EC 2.1.3.28
DYH92     EC 3.1.26.38
Dnahc92     

External Ids:    HGNC: 29531   Entrez Gene: 17702   Ensembl: ENSG000000071747   OMIM: 6033305   UniProtKB: Q9NYC93   

Export aliases for DNAH9 gene to outside databases

Previous GC identifers: GC17P011867 GC17P012616 GC17P011444 GC17P011702 GC17P011442


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DNAH9 Gene:
This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal
dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene
expresses at least two transcript variants; additional variants have been described, but their full length nature
has not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for DNAH9 Gene:
DNAH9 (dynein, axonemal, heavy chain 9) is a protein-coding gene. GO annotations related to this gene include motor activity and ATPase activity. An important paralog of this gene is DNAH5.

UniProtKB/Swiss-Prot: DYH9_HUMAN, Q9NYC9
Function: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules.
Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP

Gene Wiki entry for DNAH9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010718.17  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DNAH9 gene promoter:
         Pax-5   AML1a   AP-2gamma   C/EBPalpha   E47   Nkx6-1   AP-2beta   Hand1   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNAH9 promoter sequence
   Search Chromatin IP Primers for DNAH9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DNAH9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p12   Ensembl cytogenetic band:  17p12   HGNC cytogenetic band: 17p12

DNAH9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAH9 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P011501:  view genomic region     (about GC identifiers)

Start:
11,501,748 bp from pter      End:
11,873,065 bp from pter
Size:
371,318 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DYH9_HUMAN, Q9NYC9 (See protein sequence)
Recommended Name: Dynein heavy chain 9, axonemal  
Size: 4486 amino acids; 511877 Da
Subunit: Consists of at least two heavy chains and a number of intermediate and light chains
Secondary accessions: A2VCQ8 O15064 O95494 Q9NQ28
Alternative splicing: 3 isoforms:  Q9NYC9-1   Q9NYC9-2   Q9NYC9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DNAH9: NX_Q9NYC9

Explore proteomics data for DNAH9 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for DNAH9 (Q9NYC9)
     SVILEQV  RKLGYTF 


    See DNAH9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001363.2  NP_004653.2  

    ENSEMBL proteins: 
     ENSP00000262442   ENSP00000463782   ENSP00000414874   ENSP00000466691   ENSP00000467192  
     ENSP00000463622   ENSP00000476951  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DN: Axonemal dyneins

    Selected InterPro protein domains (see all 9):
     IPR004273 Dynein_heavy_dom
     IPR024317 Dynein_heavy_chain_D4_dom
     IPR024743 Dynein_HC_stalk
     IPR011704 ATPase_dyneun-rel_AAA
     IPR013602 Dynein_heavy_dom-2

    Graphical View of Domain Structure for InterPro Entry Q9NYC9

    ProtoNet protein and cluster: Q9NYC9

    3 Blocks protein domains:
    IPB004273 Dynein heavy chain
    IPB011704 ATPase associated with various cellular activities
    IPB013594 Dynein heavy chain


    UniProtKB/Swiss-Prot: DYH9_HUMAN, Q9NYC9
    Domain: Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other
    dynein components), and the head or motor domain. The motor contains six tandemly-linked AAA domains in the head,
    which form a ring. A stalk-like structure (formed by two of the coiled coil domains) protrudes between AAA 4 and
    AAA 5 and terminates in a microtubule-binding site. A seventh domain may also contribute to this ring; it is not
    clear whether the N-terminus or the C-terminus forms this extra domain. There are four well-conserved and two
    non-conserved ATPase sites, one per AAA domain. Probably only one of these (within AAA 1) actually hydrolyzes
    ATP, the others may serve a regulatory function
    Similarity: Belongs to the dynein heavy chain family


    Find genes that share domains with DNAH9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DYH9_HUMAN, Q9NYC9
    Function: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules.
    Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP

         Enzyme Numbers (IUBMB): EC 2.1.3.22 EC 3.1.26.32

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003774motor activity TAS8812413
    GO:0003777microtubule motor activity IEA--
    GO:0005524ATP binding IEA--
    GO:0016887ATPase activity IEA--
         
    Find genes that share ontologies with DNAH9           About GenesLikeMe


    Animal Models:
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    hsa-mir-192-5p (MIRT026555), hsa-mir-324-5p (MIRT043060)

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    2 qRT-PCR Assays for microRNAs that regulate DNAH9:
    hsa-miR-1184 hsa-miR-1205
    SwitchGear 3'UTR luciferase reporter plasmidDNAH9 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DYH9_HUMAN, Q9NYC9: Cytoplasm, cytoskeleton, cilium axoneme
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol3
    mitochondrion2
    endosome1
    golgi apparatus1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005856cytoskeleton TAS8812413
    GO:0005858axonemal dynein complex ----
    GO:0005874microtubule IEA--
    GO:0005930axoneme IDA11104725
    GO:0030286dynein complex IEA--

    Find genes that share ontologies with DNAH9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DNAH9 About    
    See pathways by source

    SuperPathContained pathways About
    1Cytoplasmic microtubules
    Cytoplasmic microtubules0.32



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DNAH9
    Interactions:

        Search GeneGlobe Interaction Network for DNAH9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DNAH9 (Q9NYC93 ENSP000002624424) via UniProtKB, MINT, STRING, and/or I2D (see all 83)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BCL6P411823, ENSP000002320144I2D: score=3 STRING: ENSP00000232014
    DNAH1ENSP000004015144STRING: ENSP00000401514
    DNAH17ENSP000003744904STRING: ENSP00000374490
    DNAH2ENSP000003738254STRING: ENSP00000373825
    DNAH3ENSP000002613834STRING: ENSP00000261383
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006928cellular component movement TAS8812413
    GO:0007018microtubule-based movement IEA--
    GO:0007283spermatogenesis TAS8703119
    GO:0008152metabolic process TAS8812413
    GO:0030030cell projection organization IEA--

    Find genes that share ontologies with DNAH9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DNAH9 (DYH9)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DNAH9 gene (2 alternative transcripts): 
    NM_001372.3  NM_004662.2  

    Unigene Cluster for DNAH9:

    Dynein, axonemal, heavy chain 9
    Hs.567259  [show with all ESTs]
    Unigene Representative Sequence: AJ404468
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262442(uc002gne.3 uc010coo.3) ENST00000579828(uc002gnd.1)
    ENST00000579406 ENST00000454412 ENST00000579602 ENST00000579813 ENST00000585197
    ENST00000583192 ENST00000584663 ENST00000578834 ENST00000579703 ENST00000580255
    ENST00000396001(uc002gnf.3) ENST00000581682 ENST00000608377
    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate DNAH9:
    hsa-miR-1184 hsa-miR-1205
    SwitchGear 3'UTR luciferase reporter plasmidDNAH9 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat DNAH9

    Additional mRNA sequence: 

    AB002355.2 AB290158.1 AF015265.1 AF257737.1 AJ132088.1 AJ404468.1 AK055990.1 AK302009.1 
    AK310137.1 BC128261.1 BC128421.1 BC153883.1 U61740.1 X99947.1 

    8 DOTS entries:

    DT.75170032  DT.75130377  DT.106011  DT.91741027  DT.97836488  DT.40115343  DT.95327051  DT.120996537 

    9 AceView cDNA sequences:

    BM985160 BX112908 BU678739 AI688720 CA314869 CB243488 AA453674 AA447742 
    BF931711 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DNAH9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCTAAGCTT
    DNAH9 Expression
    About this image


    DNAH9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Floor Plate Cells Spinal Floor Plate
             Metencephalon
     
     Brain (Nervous System)
             Medulla Oblongata
     
     Testis (Reproductive System)
    DNAH9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DNAH9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.567259
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for DNAH9 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnahc95
    Dnah91
    dynein, axonemal, heavy chain 91, 5 85.45(n)1
    87.81(a)1
      11 (40.53 cM)5
    2378061  NM_001099633.11  NP_001093103.11 
     658312825 
    chicken
    (Gallus gallus)
    Aves DNAH91 dynein, axonemal, heavy chain 9 75.31(n)
    78.48(a)
      417314  XM_415585.4  XP_415585.4 
    lizard
    (Anolis carolinensis)
    Reptilia DNAH96
    dynein, axonemal, heavy chain 9
    77(a)
    1 ↔ 1
    2(103777495-104067911)
    African clawed frog
    (Xenopus laevis)
    Amphibia dnah9-A2 dynein heavy chain 9 76.11(n)    AY100020.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dnahc112 dynein, axonemal, heavy chain 11 74.81(n)   266676  AY100021.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta kl-53
    Dhc93AB1
    microtubule-based movement motor3
    Dynein heavy chain at 93AB1
    86(a)
    (best of 4)3
    60.51(n)1
    59.78(a)1
      424851  NM_001275864.11  NP_001262793.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DYN16
    Cytoplasmic heavy chain dynein, microtubule motor ...
    20(a)
    1 → many
    XI(535647-547925) YKR054C


    ENSEMBL Gene Tree for DNAH9 (if available)
    TreeFam Gene Tree for DNAH9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DNAH9 gene
    DNAH52  DNAH22  DYNC1H12  DNAH82  DYNC2H12  DNAH32  DNAH112  DNAH72  
    DNAH62  DNAH12  DNAH102  DNAH172  
    16 SIMAP similar genes for DNAH9 using alignment to 9 protein entries:     DYH9_HUMAN (see all proteins):
    Dnahc9    Dnahc11    DNAH17    DNAH11    Dnahc3    Dnchc1
    DNAH14    DNAH5    DNAH10    DNAH6    DNAH3    DNAH1
    DNAH2    DNAH8    DNAH7    DNAH12

    Find genes that share paralogs with DNAH9           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DNAH9 (see all 8712)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0362164
    A breast cancer sample4--see VAR_0362162 T N mis40--------
    VAR_0362144
    A breast cancer sample4--see VAR_0362142 R L mis40--------
    VAR_0362154
    A breast cancer sample4--see VAR_0362152 D H mis40--------
    rs2015325861,2
    Cuntested111573010(+) GGCTGG/AATGAA 2 /* /W stg11Minor allele frequency- A:0.00EU 1323
    rs1469935751,2
    Cuntested111583092(+) GATGCA/GTTTAT 2 A syn10--------
    rs1496747951,2
    Cuntested111648297(+) TCTTTC/TCCGCC 2 P S mis10--------
    rs1410311121,2
    C,Funtested111648335(+) AACTTC/TGAAGC 2 F syn12Minor allele frequency- T:0.00NA EU 5873
    rs1172970651,2
    F--11499777(+) AGGAGC/ACTTCA 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs38097291,2
    C,F,H--11499840(-) CAACAT/GACATA 1 -- us2k120Minor allele frequency- G:0.17NS EA NA 2464
    rs1465633871,2
    --11499955(+) GTATAC/TGAAAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DNAH9 (11501748 - 11751748 bp, first 250kb of DNAH9)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for DNAH9 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2676335CNV Deletion23128226
    esv3161CNV Deletion18987735
    esv2715650CNV Deletion23290073
    esv1254302CNV Deletion17803354
    esv2715655CNV Deletion23290073
    esv2715652CNV Deletion23290073
    esv1274728CNV Deletion17803354
    esv2663712CNV Deletion23128226
    esv2715657CNV Deletion23290073
    esv2715654CNV Deletion23290073

    Human Gene Mutation Database (HGMD): DNAH9
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DNAH9
    DNA2.0 Custom Variant and Variant Library Synthesis for DNAH9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603330    OMIM disorders: --

    2 diseases from the University of Copenhagen DISEASES database for DNAH9:
    Primary ciliary dyskinesia     Situs inversus

    Find genes that share disorders with DNAH9           About GenesLikeMe

    Genetic Association Database (GAD): DNAH9
    Human Genome Epidemiology (HuGE) Navigator: DNAH9 (1 document)

    Export disorders for DNAH9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DNAH9 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with DNAH9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Axonemal beta heavy chain dynein DNAH9: cDNA sequence, genomic structure, and investigation of its role in primary ciliary dyskinesia. (PubMed id 11247663)1, 2, 3, 9 Bartoloni L.... Antonarakis S.E. (Genomics 2001)
    2. Characterization of an axonemal dynein heavy chain expressed early in airway epithelial ciliogenesis. (PubMed id 11104725)1, 2, 9 Reed W.... Collier A.M. (Am. J. Respir. Cell Mol. Biol. 2000)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (DNA Res. 1997)
    5. Multiple mouse chromosomal loci for dynein-based motility. (PubMed id 8812413)1, 3 Vaughan K.T....Vallee R.B. (Genomics 1996)
    6. Axonemal dynein expression in human fetal tracheal epithelium. (PubMed id 11839535)1, 9 Carson J.L....Collier A.M. (Am. J. Physiol. Lung Cell Mol. Physiol. 2002)
    7. A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. (PubMed id 23049088)1 Meng W....Malecaze F. (amp 2012)
    8. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    9. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)
    10. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. (PubMed id 17903303)4 O'Donnell C.J....Demissie S. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1770 HGNC: 2953 AceView: DNAH9.1 Ensembl:ENSG00000007174 euGenes: HUgn1770
    ECgene: DNAH9 H-InvDB: DNAH9

    (According to HUGE)
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    HUGE: KIAA0357

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DNAH9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for DNAH9 gene:
    Search GeneIP for patents involving DNAH9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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