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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DNAH7 Gene

protein-coding   GIFtS: 55
GCID: GC02M196602

Dynein, Axonemal, Heavy Chain 7

(Previous names: dynein, axonemal, heavy polypeptide 7)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dynein, Axonemal, Heavy Chain 71 2     hDHC22 3
Dynein, Axonemal, Heavy Polypeptide 71 2     Axonemal Dynein Heavy Chain 72
Axonemal Beta Dynein Heavy Chain 72 3     Dynein Heavy Chain 7, Axonemal2
Ciliary Dynein Heavy Chain 72 3     KIAA09443
Dynein Heavy Chain-Like Protein 22 3     

External Ids:    HGNC: 186611   Entrez Gene: 561712   Ensembl: ENSG000001189977   OMIM: 6100615   UniProtKB: Q8WXX03   

Export aliases for DNAH7 gene to outside databases

Previous GC identifers: GC02M194792 GC02M195315 GC02M196566 GC02M196804 GC02M196427 GC02M196310 GC02M188455


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DNAH7 Gene:
DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 (PubMed 11877439)).(supplied
by OMIM, Mar 2008)

GeneCards Summary for DNAH7 Gene: 
DNAH7 (dynein, axonemal, heavy chain 7) is a protein-coding gene. Diseases associated with DNAH7 include primary ciliary dyskinesia, and among its related super-pathways are Cytoskeleton remodeling Neurofilaments. GO annotations related to this gene include microtubule motor activity and ATPase activity. An important paralog of this gene is DNAH5.

UniProtKB/Swiss-Prot: DYH7_HUMAN, Q8WXX0
Function: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules.
Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DNAH7 gene promoter:
         Nkx3-1   AML1a   FOXD3   Nkx3-1 v1   CUTL1   Nkx3-1 v2   c-Rel   FOXJ2 (long isoform)   Nkx3-1 v3   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNAH7 promoter sequence
   Search SABiosciences Chromatin IP Primers for DNAH7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAH7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q32.3   Ensembl cytogenetic band:  2q32.3   HGNC cytogenetic band: 2q33.1

DNAH7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAH7 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M196602:  view genomic region     (about GC identifiers)

Start:
196,602,427 bp from pter      End:
196,933,536 bp from pter
Size:
331,110 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DYH7_HUMAN, Q8WXX0 (See protein sequence)
Recommended Name: Dynein heavy chain 7, axonemal  
Size: 4024 amino acids; 461159 Da
Subunit: The dynein complex consists of at least two heavy chains and a number of intermediate and light chains
(By similarity)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme
Sequence caution: Sequence=BAA76788.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=CAB06055.1; Type=Frameshift; Positions=1502; Sequence=CAH18445.1; Type=Erroneous initiation;
Note=Translation N-terminally shortened; Sequence=CAH18445.1; Type=Erroneous translation; Note=Wrong choice of
CDS;
Secondary accessions: B8ZZX8 O00433 O95492 Q4G152 Q53QX7 Q53S64 Q53T02 Q68CY5 Q8N1Z2 Q9UMS3
Q9Y2F3
Alternative splicing: 4 isoforms:  Q8WXX0-1   Q8WXX0-2   Q8WXX0-3   Q8WXX0-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DNAH7: NX_Q8WXX0

Explore proteomics data for DNAH7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WXX0

  • DNAH7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DNAH7 Protein Expression
    REFSEQ proteins: NP_061720.2  
    ENSEMBL proteins: 
     ENSP00000386912   ENSP00000311273   ENSP00000409732   ENSP00000386260   ENSP00000407444  

    Human Recombinant Protein Products for DNAH7: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DNAH7 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005858axonemal dynein complex NAS9373155
    GO:0005874microtubule IEA--
    GO:0005929cilium IDA11877439
    GO:0030286dynein complex ----
    GO:0035085cilium axoneme IEA--

    DNAH7 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    EFHAND: EF-hand domain containing
    DN: Axonemal dyneins

    5/10 InterPro protein domains (see all 10):
     IPR004273 Dynein_heavy_dom
     IPR002048 EF_hand_dom
     IPR024317 Dynein_heavy_chain_D4_dom
     IPR024743 Dynein_HC_stalk
     IPR013602 Dynein_heavy_dom-2

    Graphical View of Domain Structure for InterPro Entry Q8WXX0

    ProtoNet protein and cluster: Q8WXX0

    3 Blocks protein domains:
    IPB002198 Short-chain dehydrogenase/reductase SDR
    IPB004273 Dynein heavy chain
    IPB011704 ATPase associated with various cellular activities


    UniProtKB/Swiss-Prot: DYH7_HUMAN, Q8WXX0
    Domain: Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other
    dynein components), and the head or motor domain. The motor contains six tandemly-linked AAA domains in the head,
    which form a ring. A stalk-like structure (formed by two of the coiled coil domains) protrudes between AAA 4 and
    AAA 5 and terminates in a microtubule-binding site. A seventh domain may also contribute to this ring; it is not
    clear whether the N-terminus or the C-terminus forms this extra domain. There are four well-conserved and two
    non-conserved ATPase sites, one per AAA domain. Probably only one of these (within AAA 1) actually hydrolyzes
    ATP, the others may serve a regulatory function (By similarity)
    Similarity: Belongs to the dynein heavy chain family


    DNAH7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DYH7_HUMAN, Q8WXX0
    Function: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules.
    Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By
    similarity)
    Induction: Up-regulated during ciliogenesis (at protein level)

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003777microtubule motor activity NAS9373155
    GO:0005509calcium ion binding IEA--
    GO:0005524ATP binding IEA--
    GO:00083127S RNA binding ----
         
    DNAH7 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DNAH7 
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    hsa-miR-205* hsa-miR-589*
    SwitchGear 3'UTR luciferase reporter plasmidDNAH7 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DNAH7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Cytoskeleton remodeling Neurofilaments
    Cytoplasmic microtubules0.32

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for DNAH7
        Cytoplasmic microtubules




    DNAH7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DNAH7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/37 Interacting proteins for DNAH7 (Q8WXX02, 3 ENSP000003112734) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GABARAPL2P605203, ENSP000000372434I2D: score=1 STRING: ENSP00000037243
    DNAH1ENSP000004015144STRING: ENSP00000401514
    DNAH17ENSP000003744904STRING: ENSP00000374490
    DNAH2ENSP000003738254STRING: ENSP00000373825
    DNAH3ENSP000002613834STRING: ENSP00000261383
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001539ciliary or bacterial-type flagellar motility NAS9373155
    GO:0006614SRP-dependent cotranslational protein targeting to membrane ----
    GO:0007018microtubule-based movement IEA--

    DNAH7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DNAH7 (DYH7)

    Search CenterWatch for drugs/clinical trials and news about DNAH7 / DYH7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DNAH7 gene: 
    NM_018897.2  

    Unigene Cluster for DNAH7:

    Dynein, axonemal, heavy chain 7
    Hs.97403  [show with all ESTs]
    Unigene Representative Sequence: AB023161
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409063(uc002uti.4) ENST00000312428(uc002utj.4) ENST00000484183
    ENST00000438565 ENST00000493844 ENST00000475293 ENST00000410072 ENST00000427816

    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate DNAH7:
    hsa-miR-205* hsa-miR-589*
    SwitchGear 3'UTR luciferase reporter plasmidDNAH7 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB023161.2 AF327442.1 AJ132084.1 AK094515.1 BC029567.1 CR749651.1 Z83801.1 

    7 DOTS entries:

    DT.208557  DT.95365314  DT.99933157  DT.100663598  DT.91996126  DT.92420015  DT.95193339 

    24/40 AceView cDNA sequences (see all 40):

    BX503614 AF327442 BX479352 BX503613 AA382623 AB023161 NM_018897 AI866330 
    AV729438 BP368825 BC029567 AL599611 AK094515 AI241846 BG772885 BM983036 
    CR749651 BG204650 AV728842 CB047657 AA393310 AA766761 BG216298 BG216870 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DNAH7 expression in normal human tissues (normalized intensities)      DNAH7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTCTTCCCT
    DNAH7 Expression
    About this image


    DNAH7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/20 selected tissues (see all 20) fully expand
     
     Epithelium (Uncategorized)    fully expand to see all 5 entries
             esophagus ; squamous epithelial cells   
             bronchial epithelia   
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             testis ; cells in seminiferus ducts   
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
             Trigeminal Ganglion   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             colon ; peripheral nerve/ganglion   
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             lung ; macrophages   

    See DNAH7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DNAH7

    SOURCE GeneReport for Unigene cluster: Hs.97403

    UniProtKB/Swiss-Prot: DYH7_HUMAN, Q8WXX0
    Tissue specificity: Detected in brain, testis and trachea. Detected in bronchial cells (at protein level)

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAH7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DNAH7 gene from 5/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnahc7a5
    Dnahc7b1
    dynein, axonemal, heavy chain 7A5
    dynein, axonemal, heavy chain 7B1
    85.08(n)1
    88.87(a)1
      1 (26.99 cM)5
    2270581  NM_001160386.11  NP_001153858.11 
     533970025 
    chicken
    (Gallus gallus)
    Aves DNAH71 dynein, axonemal, heavy chain 7 75.54(n)
    78.03(a)
      424048  XM_003641574.1  XP_003641622.1 
    lizard
    (Anolis carolinensis)
    Reptilia DNAH76
    Uncharacterized protein
    82(a)
    1 ↔ 1
    GL343280.1(910044-1102279)
    zebrafish
    (Danio rerio)
    Actinopterygii dnah71 dynein, axonemal, heavy chain 7 68.66(n)
    74.26(a)
      561639  XM_685051.3  XP_690143.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta Dhc36C1 , 3 microtubule-based movement dynein
    ATPase3
    Dynein heavy chain at 36C1
    56(a)
    (best of 5)3
    56.91(n)1
    57.23(a)1
      2 36C103
    350611  NM_078867.31  NP_523591.21 


    ENSEMBL Gene Tree for DNAH7 (if available)
    TreeFam Gene Tree for DNAH7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DNAH7 gene
    DNAH52  DNAH22  DYNC1H12  DNAH82  DYNC2H12  DNAH92  DNAH32  DNAH112  
    DNAH62  DNAH12  DNAH102  DNAH172  
    11 SIMAP similar genes for DNAH7 using alignment to 3 protein entries:     DYH7_HUMAN (see all proteins):
    DNAH3    DNAH12    DNAH1    DNAH2    DNAH6    DNAH10
    DNAH17    DNAH11    DNAH5    DNAH8    DNAH9

    DNAH7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6542 SNPs in DNAH7 are shown (see all 6542)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs766321281,2
    C,Funtested1196664077(+) AGCACG/AAAAAT 2 /F syn11Minor allele frequency- A:0.04EA 120
    rs1492126591,2
    Cuntested1196746611(+) GTATCG/AAATTG 2 /R /* stg11Minor allele frequency- A:0.00EU 1323
    rs775703411,2
    F--196603039(+) AAAAAT/CAGTTT 1 -- int11Minor allele frequency- C:0.02WA 118
    rs106575331,2
    C--196603136(+) ATGAT-/A/A   
       A
    /AAA
    AAAAA
    2 -- int1 cds11CSA 2
    rs1500162371,2
    C--196603451(+) TTTGA-/TCTT  
            
    TCTTT
    1 -- int10--------
    rs1449785451,2
    --196603510(+) TAATTC/TAATTT 1 -- int10--------
    rs1864356061,2
    --196603555(+) GATGAC/TAGGAC 1 -- int10--------
    rs1152043511,2
    F--196603655(+) TATTTC/TTCCCA 1 -- int11Minor allele frequency- T:0.02WA 118
    rs168393721,2
    C,F--196603797(+) AGAATT/GTTTAT 1 -- int18Minor allele frequency- G:0.17NA WA CSA 380
    rs1476005951,2
    C--196603825(+) TTCAGA/GAGAAT 1 -- int10--------

    HapMap Linkage Disequilibrium report for DNAH7 (196602427 - 196852427 bp, first 250kb of DNAH7)

    Structural Variations
         Database of Genomic Variants (DGV) 10/21 variations for DNAH7 (see all 21):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2721333CNV Deletion23290073
    esv2233474CNV Deletion18987734
    esv3418CNV Deletion18987735
    esv2489659CNV Deletion19546169
    esv2721334CNV Deletion23290073
    esv2580785CNV Deletion19546169
    esv2721332CNV Deletion23290073
    esv2721331CNV Deletion23290073
    esv2215403CNV Deletion18987734
    esv2662087CNV Deletion23128226


    Human Gene Mutation Database (HGMD): DNAH7
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610061    OMIM disorders: --

    2 diseases for DNAH7:    About MalaCards
    primary ciliary dyskinesia    

    1 disease from the University of Copenhagen DISEASES database for DNAH7:
    Primary ciliary dyskinesia

    DNAH7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): DNAH7
    Human Genome Epidemiology (HuGE) Navigator: DNAH7 (1 document)

    Export disorders for DNAH7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DNAH7 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with DNAH7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of dynein heavy chain 7 as an inner arm component of human cilia that is synthesized but not assembled in a case of primary ciliary dyskinesia. (PubMed id 11877439)1, 2, 3 Zhang Y.J.... Ostrowski L.E. (2002)
    2. Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. (PubMed id 9373155)1, 2, 3 Neesen J.... Schmid M. (1997)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2 Nagase T.... Ohara O. (1999)
    6. Why do cellular proteins linked to K63-polyubiquitin c hains not associate with proteasomes? (PubMed id 23314748)1 Nathan J.A....Goldberg A.L. (2013)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. The SH3 domain of postsynaptic density 95 mediates inf lammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (2010)
    9. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PubMed id 17903292)4 Hwang S.J....Fox C.S. (2007)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56171 HGNC: 18661 AceView: DNAH7 Ensembl:ENSG00000118997 euGenes: HUgn56171
    ECgene: DNAH7 H-InvDB: DNAH7

    (According to HUGE)
    About This Section
    HUGE: KIAA0944

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DNAH7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DNAH7 gene:
    Search GeneIP for patents involving DNAH7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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