Aliases for DNAH14 Gene
External Ids for DNAH14 Gene
Previous HGNC Symbols for DNAH14 Gene
Previous GeneCards Identifiers for DNAH14 Gene
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH14 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]
GeneCards Summary for DNAH14 Gene
DNAH14 (Dynein, Axonemal, Heavy Chain 14) is a Protein Coding gene. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include microtubule motor activity.
UniProtKB/Swiss-Prot for DNAH14 Gene
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).