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DNAAF2 Gene

protein-coding   GIFtS: 45
GCID: GC14M050092

Dynein, Axonemal, Assembly Factor 2

(Previous name: chromosome 14 open reading frame 104)
(Previous symbol: C14orf104)
  See DNAAF2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dynein, Axonemal, Assembly Factor 21 2     CILD102 5
C14orf1041 2 3 5     Chromosome 14 Open Reading Frame 1041
KTU2 3 5     PF132
kintoun1 2     Protein Kintoun2
Dynein Assembly Factor 2, Axonemal2 3     

External Ids:    HGNC: 201881   Entrez Gene: 551722   Ensembl: ENSG000001655067   OMIM: 6125175   UniProtKB: Q9NVR53   

Export aliases for DNAAF2 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DNAAF2 Gene:
This gene encodes a highly conserved protein involved in the preassembly of dynein arm complexes which power
cilia. These complexes are found in some cilia and are assembled in the cytoplasm prior to transport for cilia
formation. Mutations in this gene have been associated with primary ciliary dyskinesia. Multiple transcript
variants encoding different isoforms have been found for this gene.(provided by RefSeq, Oct 2009)

GeneCards Summary for DNAAF2 Gene:
DNAAF2 (dynein, axonemal, assembly factor 2) is a protein-coding gene. Diseases associated with DNAAF2 include primary ciliary dyskinesia10: dnaaf2-related primary ciliary dyskinesia, and ciliary dyskinesia, primary, 19.

UniProtKB/Swiss-Prot: KTU_HUMAN, Q9NVR5
Function: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in
cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar
transport loads them for the ciliary compartment

Gene Wiki entry for DNAAF2 (C14orf104) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Search for regulatory transcription factor binding sites for DNAAF2
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for DNAAF2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DNAAF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q21.3   Ensembl cytogenetic band:  14q21.3   HGNC cytogenetic band: 14q21.3

DNAAF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAAF2 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M050092:  view genomic region     (about GC identifiers)

Start:
50,091,892 bp from pter      End:
50,101,948 bp from pter
Size:
10,057 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: KTU_HUMAN, Q9NVR5 (See protein sequence)
Recommended Name: Protein kintoun  
Size: 837 amino acids; 91114 Da
Subunit: Interacts with DNAI2 and HSPA1A (By similarity). Interacts with DYX1C1
Sequence caution: Sequence=BAA91684.1; Type=Erroneous initiation; Sequence=CAD66572.1; Type=Erroneous initiation;
Secondary accessions: B9WS54 C0JAP7 Q86TR1 Q86TY8 Q969Z5
Alternative splicing: 2 isoforms:  Q9NVR5-1   Q9NVR5-2   (May be due to exon skipping)

Explore the universe of human proteins at neXtProt for DNAAF2: NX_Q9NVR5

Explore proteomics data for DNAAF2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys558
  • Modification sites at PhosphoSitePlus

  • See DNAAF2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001077377.1  NP_060609.2  

    ENSEMBL proteins: 
     ENSP00000298292   ENSP00000384862  

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    Browse Proteins at Cloud-Clone Corp.

     
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    antibodies-online peptides for DNAAF2

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    antibodies-online antibodies for DNAAF2 (4 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR012981 PIH

    Graphical View of Domain Structure for InterPro Entry Q9NVR5

    ProtoNet protein and cluster: Q9NVR5

    UniProtKB/Swiss-Prot: KTU_HUMAN, Q9NVR5
    Similarity: Belongs to the PIH1 family. Kintoun subfamily


    Find genes that share domains with DNAAF2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KTU_HUMAN, Q9NVR5
    Function: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in
    cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar
    transport loads them for the ciliary compartment

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with DNAAF2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for DNAAF2:
     Decreased Wnt reporter activit  Increased gamma-H2AX phosphory 

         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Dnaaf2):
     cardiovascular system  digestive/alimentary  growth/size/body  mortality/aging  nervous system 
     respiratory system 

    Find genes that share phenotypes with DNAAF2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Dnaaf2tm1.1Mkis for DNAAF2

       genOway: Develop your customized and physiologically relevant rodent model for DNAAF2

    miRNA
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    miRTarBase miRNAs that target DNAAF2:
    hsa-mir-335-5p (MIRT016921)

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    1 qRT-PCR Assays for microRNA that regulate DNAAF2:
    hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidDNAAF2 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KTU_HUMAN, Q9NVR5: Cytoplasm. Note=Localizes in the apical cytoplasm around the gamma-tubulin-positive
    pericentriolar region, not in the cilia

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA19052621

    Find genes that share ontologies with DNAAF2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DNAAF2
    Interactions:

        Search GeneGlobe Interaction Network for DNAAF2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DNAAF2 (ENSP000002982924) via UniProtKB, MINT, STRING, and/or I2D (see all 59)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NOP58ENSP000002642794STRING: ENSP00000264279
    NOLC1ENSP000003590244STRING: ENSP00000359024
    C7orf50ENSP000003500114STRING: ENSP00000350011
    FA2HENSP000002193684STRING: ENSP00000219368
    EXOSC10ENSP000003661354STRING: ENSP00000366135
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010033response to organic substance ----
    GO:0032526response to retinoic acid IEA--
    GO:0060285cilium-dependent cell motility IMP19052621
    GO:0070286axonemal dynein complex assembly IMP19052621
    GO:0071973bacterial-type flagellum-dependent cell motility IMP19052621

    Find genes that share ontologies with DNAAF2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DNAAF2 (KTU)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DNAAF2 gene (2 alternative transcripts): 
    NM_001083908.1  NM_018139.2  

    Unigene Cluster for DNAAF2:

    Dynein, axonemal, assembly factor 2
    Hs.231761  [show with all ESTs]
    Unigene Representative Sequence: NM_018139
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000298292(uc001wws.4) ENST00000406043(uc001wwt.4)
    miRNA
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    hsa-miR-590-3p
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    Inhib. RNA
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    Additional mRNA sequence: 

    AK001425.1 BC011400.1 BC013322.1 BX248264.1 BX248765.1 FJ158843.1 

    7 DOTS entries:

    DT.100782792  DT.310557  DT.92430654  DT.95280786  DT.100702858  DT.92430650  DT.100696518 

    Selected AceView cDNA sequences (see all 108):

    BX248765 BM784552 CB163897 BX248264 BM927175 BG428211 BI821093 BC011400 
    CR619602 AA331943 T10804 BX368047 BE047089 CB963351 BM974612 BE675154 
    BI917227 BV180098 NM_018139 BI551983 BU680642 AK001425 BG202679 AI935508 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for DNAAF2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3
    SP1:                        
    SP2:              -         


    ECgene alternative splicing isoforms for DNAAF2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DNAAF2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGGAAATTG
    DNAAF2 Expression
    About this image

    DNAAF2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DNAAF2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.231761
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DNAAF2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnaaf21 , 5 RIKEN cDNA 1110034A24 gene5
    dynein, axonemal assembly factor 21
    76.42(n)1
    67.25(a)1
      12 (28.73 cM)5
    1090651  NM_027269.31  NP_081545.31 
     691890875 
    chicken
    (Gallus gallus)
    Aves DNAAF21 dynein, axonemal, assembly factor 2 49.49(n)
    37.04(a)
      423566  XM_421456.4  XP_421456.4 
    lizard
    (Anolis carolinensis)
    Reptilia DNAAF26
    dynein, axonemal, assembly factor 2
    57(a)
    1 ↔ 1
    GL343560.1(53385-53954)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia dnaaf21 dynein, axonemal, assembly factor 2 52.34(n)
    44.05(a)
      779929  NM_001079006.1  NP_001072474.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dnaaf26
    dynein, axonemal, assembly factor 2
    28(a)
    1 ↔ 1
    17(4907-7536) ENSDARG00000041134
    fruit fly
    (Drosophila melanogaster)
    Insecta Nop17l6
    Nop17 like
    23(a)
    1 ↔ 1
    2R(3688286-3693904)


    ENSEMBL Gene Tree for DNAAF2 (if available)
    TreeFam Gene Tree for DNAAF2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DNAAF2 gene
    1 SIMAP similar gene for DNAAF2 using alignment to 1 protein entry:     KTU_HUMAN:
    C14orf104

    Find genes that share paralogs with DNAAF2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DNAAF2 (see all 351)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1831854521,2
    --31074706(+) TGTTTC/TAATAT 2 -- ds50010--------
    rs105681291,2
    C--31074814(+) TAGTTTGTG/-  
            
    TGACA
    2 -- ds50011Minor allele frequency- -:0.50NA 2
    rs21477121,2
    C,F,O,A--31074843(-) TAGTAT/CTTTTC 2 -- ds500111Minor allele frequency- C:0.47NA WA CSA EA 509
    rs1867114351,2
    --31074855(+) ATTTTA/GTCTGG 2 -- ds50010--------
    rs1911690461,2
    --31074873(+) GTATCA/GTAATT 2 -- ds50010--------
    rs1467991031,2
    --31074877(+) CGTAAC/TTGTTT 2 -- ds50010--------
    rs1840058991,2
    --31074963(+) CTGAGA/GAACAG 2 -- ds50010--------
    rs1405992111,2
    --31074987(+) CCCCCA/CACACA 2 -- ds50010--------
    rs121601,2
    C,F,A--31075091(-) GTTAAT/ATTTTG 2 -- ut3110Minor allele frequency- A:0.48NA WA CSA EA 507
    rs2017533561,2
    --31075286(+) TGCAA-/TTTTTT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for DNAAF2 (50091892 - 50101948 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for DNAAF2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv28926CNV Gain+Loss19812545

    Human Gene Mutation Database (HGMD): DNAAF2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DNAAF2
    DNA2.0 Custom Variant and Variant Library Synthesis for DNAAF2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612517   
    OMIM disorders: 612518  
    UniProtKB/Swiss-Prot: KTU_HUMAN, Q9NVR5
  • Ciliary dyskinesia, primary, 10 (CILD10) [MIM:612518]: A disorder characterized by abnormalities of
    motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to
    defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of
    sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to
    dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is
    referred to as Kartagener syndrome. Note=The disease is caused by mutations affecting the gene represented in
    this entry

  • 2 diseases for DNAAF2:    
    About MalaCards
    primary ciliary dyskinesia10: dnaaf2-related primary ciliary dyskinesia    ciliary dyskinesia, primary, 19


    Find genes that share disorders with DNAAF2           About GenesLikeMe


    Export disorders for DNAAF2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DNAAF2 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with DNAAF2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DYX1C1 is required for axonemal dynein assembly and ciliary motility. (PubMed id 23872636)1, 2 Tarkar A.... Omran H. (Nat. Genet. 2013)
    2. Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. (PubMed id 19052621)1, 2 Omran H....Takeda H. (Nature 2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (Nature 2003)
    6. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (Mol. Syst. Biol. 2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55172 HGNC: 20188 AceView: C14orf104 Ensembl:ENSG00000165506 euGenes: HUgn55172
    ECgene: DNAAF2 H-InvDB: DNAAF2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for DNAAF2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DNAAF2 gene:
    Search GeneIP for patents involving DNAAF2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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