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Aliases for DMRTC1B Gene

Aliases for DMRTC1B Gene

  • DMRT Like Family C1B 2 3
  • DMRT-Like Family C1B 2 5

External Ids for DMRTC1B Gene

Previous GeneCards Identifiers for DMRTC1B Gene

  • GC0XU900857
  • GC0XP071916
  • GC0XP072064

Summaries for DMRTC1B Gene

GeneCards Summary for DMRTC1B Gene

DMRTC1B (DMRT Like Family C1B) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is DMRTC1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DMRTC1B Gene

Genomics for DMRTC1B Gene

Regulatory Elements for DMRTC1B Gene

Enhancers for DMRTC1B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around DMRTC1B on UCSC Golden Path with GeneCards custom track

Promoters for DMRTC1B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around DMRTC1B on UCSC Golden Path with GeneCards custom track

Genomic Location for DMRTC1B Gene

72,777,009 bp from pter
72,848,802 bp from pter
71,794 bases
Plus strand

Genomic View for DMRTC1B Gene

Genes around DMRTC1B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DMRTC1B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DMRTC1B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DMRTC1B Gene

Proteins for DMRTC1B Gene

  • Protein details for DMRTC1B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Doublesex- and mab-3-related transcription factor C1
    Protein Accession:
    Secondary Accessions:
    • Q5HYR0
    • Q5U5K2
    • Q8N6L3
    • Q96SD3

    Protein attributes for DMRTC1B Gene

    192 amino acids
    Molecular mass:
    20139 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DMRTC1B Gene


neXtProt entry for DMRTC1B Gene

Proteomics data for DMRTC1B Gene at MOPED

Post-translational modifications for DMRTC1B Gene

No Post-translational modifications

Other Protein References for DMRTC1B Gene

No data available for DME Specific Peptides for DMRTC1B Gene

Domains & Families for DMRTC1B Gene

Protein Domains for DMRTC1B Gene


Suggested Antigen Peptide Sequences for DMRTC1B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the DMRT family.
  • Belongs to the DMRT family.
genes like me logo Genes that share domains with DMRTC1B: view

No data available for Gene Families for DMRTC1B Gene

Function for DMRTC1B Gene

Gene Ontology (GO) - Molecular Function for DMRTC1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042803 protein homodimerization activity IBA --
genes like me logo Genes that share ontologies with DMRTC1B: view

Phenotypes for DMRTC1B Gene

GenomeRNAi human phenotypes for DMRTC1B:
genes like me logo Genes that share phenotypes with DMRTC1B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DMRTC1B Gene

Localization for DMRTC1B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DMRTC1B Gene

Pathways & Interactions for DMRTC1B Gene

SuperPathways for DMRTC1B Gene

No Data Available

Interacting Proteins for DMRTC1B Gene

Selected Interacting proteins: Q5HYR2-DMRTC_HUMAN for DMRTC1B Gene via I2D

Gene Ontology (GO) - Biological Process for DMRTC1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with DMRTC1B: view

No data available for Pathways by source and SIGNOR curated interactions for DMRTC1B Gene

Drugs & Compounds for DMRTC1B Gene

No Compound Related Data Available

Transcripts for DMRTC1B Gene

mRNA/cDNA for DMRTC1B Gene

(4) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DMRTC1B Gene

DMRT-like family C1B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DMRTC1B Gene

No ASD Table

Relevant External Links for DMRTC1B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DMRTC1B Gene

mRNA expression in normal human tissues for DMRTC1B Gene

mRNA differential expression in normal tissues according to GTEx for DMRTC1B Gene

This gene is overexpressed in Pituitary (x4.6), Brain - Cortex (x4.5), Brain - Hypothalamus (x4.5), Brain - Anterior cingulate cortex (BA24) (x4.1), Brain - Nucleus accumbens (basal ganglia) (x4.1), and Brain - Frontal Cortex (BA9) (x4.1).

SOURCE GeneReport for Unigene cluster for DMRTC1B Gene Hs.712728

mRNA Expression by UniProt/SwissProt for DMRTC1B Gene

Tissue specificity: Predominantly expressed in kidney, pancreas, ovary and testis. Detected in brain and in many other tissues.
genes like me logo Genes that share expression patterns with DMRTC1B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for DMRTC1B Gene

Orthologs for DMRTC1B Gene

This gene was present in the common ancestor of mammals.

Orthologs for DMRTC1B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MGC140080 36
  • 28 (a)
(Canis familiaris)
Mammalia -- 36
  • 32 (a)
-- 36
  • 37 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 19 (a)
(Mus musculus)
Mammalia Dmrtc1a 36
  • 40 (a)
Dmrtc1b 36
  • 29 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 17 (a)
(Pan troglodytes)
Mammalia -- 36
  • 100 (a)
Species with no ortholog for DMRTC1B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for DMRTC1B Gene

Gene Tree for DMRTC1B (if available)
Gene Tree for DMRTC1B (if available)

Paralogs for DMRTC1B Gene

Paralogs for DMRTC1B Gene

(1) SIMAP similar genes for DMRTC1B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with DMRTC1B: view

Variants for DMRTC1B Gene

Sequence variations from dbSNP and Humsavar for DMRTC1B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1009696 -- 72,793,108(-) ACGTG(A/C)GGGAG intron-variant
rs1011191 -- 72,804,534(+) CCAGG(C/G)ACTGT intron-variant
rs1011192 -- 72,804,543(+) GTATC(A/T)TGGCT intron-variant
rs3890576 -- 72,807,629(-) CCAAG(C/T)CAGAA intron-variant
rs4314815 -- 72,801,699(-) ACTCT(C/T)CCCAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DMRTC1B Gene

Variant ID Type Subtype PubMed ID
nsv7450 OTHER Inversion 18451855

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for DMRTC1B Gene

Disorders for DMRTC1B Gene

Relevant External Links for DMRTC1B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for DMRTC1B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DMRTC1B Gene

Publications for DMRTC1B Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  3. Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination. (PMID: 11863363) Ottolenghi C. … McElreavey K. (Genomics 2002) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for DMRTC1B Gene

Sources for DMRTC1B Gene