Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DMRTA2 Gene

protein-coding   GIFtS: 42
GCID: GC01M050883

DMRT-Like Family A2

  Search for DMRTA2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DMRT-Like Family A21 2
Doublesex- And Mab-3-Related Transcription Factor 52 3
Doublesex- And Mab-3-Related Transcription Factor A22
DMRT53

External Ids:    HGNC: 139081   Entrez Gene: 639502   Ensembl: ENSG000001427007   OMIM: 6148045   UniProtKB: Q96SC83   

Export aliases for DMRTA2 gene to outside databases

Previous GC identifers: GC01M050508 GC01M049773 GC01M050242 GC01M050254 GC01M050243 GC01M050596 GC01M050656 GC01M049001


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DMRTA2 Gene: 
DMRTA2 (DMRT-like family A2) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and metal ion binding. An important paralog of this gene is DMRT2.

UniProtKB/Swiss-Prot: DMTA2_HUMAN, Q96SC8
Function: May be involved in sexual development




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DMRTA2 gene promoter:
         Max1   USF1   Pax-5   SREBP-1c   N-Myc   SREBP-1a   Ik-2   CP2   USF-1   c-Myb   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for DMRTA2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DMRTA2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.3   Ensembl cytogenetic band:  1p32.3   HGNC cytogenetic band: 1p33

DMRTA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DMRTA2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M050883:  view genomic region     (about GC identifiers)

Start:
50,883,222 bp from pter      End:
50,889,172 bp from pter
Size:
5,951 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DMTA2_HUMAN, Q96SC8 (See protein sequence)
Recommended Name: Doublesex- and mab-3-related transcription factor A2  
Size: 542 amino acids; 53356 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q5TFQ3

Explore the universe of human proteins at neXtProt for DMRTA2: NX_Q96SC8

Explore proteomics data for DMRTA2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96SC8

  • DMRTA2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DMRTA2 Protein Expression
    REFSEQ proteins: NP_115486.1  
    ENSEMBL proteins: 
     ENSP00000399370   ENSP00000383909  

    Human Recombinant Protein Products for DMRTA2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for DMRTA2
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for DMRTA2
    GenScript Custom Purified and Recombinant Proteins Services for DMRTA2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DMRTA2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    DMRTA2 for ontologies           About GeneDecksing



    DMRTA2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for DMRTA2
    GenScript Custom Superior Antibodies Services for DMRTA2
    Novus Biologicals DMRTA2 Antibodies
    Abcam antibodies for DMRTA2
    Cloud-Clone Corp. Antibodies for DMRTA2 
    ThermoFisher Antibodies for DMRTA2
    LSBio Antibodies in human, mouse, rat for DMRTA2 

    Assay Products for DMRTA2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for DMRTA2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DMRTA2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for DMRTA2 
    Cloud-Clone Corp. CLIAs for DMRTA2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR009060 UBA-like
     IPR005173 DMA
     IPR026607 DMRT/dsx/mab-3
     IPR001275 DM_DNA-bd

    Graphical View of Domain Structure for InterPro Entry Q96SC8

    ProtoNet protein and cluster: Q96SC8

    1 Blocks protein domain: IPB001275 DM DNA-binding

    UniProtKB/Swiss-Prot: DMTA2_HUMAN, Q96SC8
    Similarity: Belongs to the DMRT family
    Similarity: Contains 1 DM DNA-binding domain


    DMRTA2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DMTA2_HUMAN, Q96SC8
    Function: May be involved in sexual development

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding ----
    GO:0043565sequence-specific DNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    DMRTA2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DMRTA2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DMRTA2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DMRTA2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DMRTA2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DMRTA2
    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate DMRTA2 (see all 41):
    hsa-miR-106a hsa-miR-519a hsa-miR-3161 hsa-miR-374c hsa-miR-1273d hsa-miR-149 hsa-miR-93 hsa-miR-520g
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DMRTA2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DMRTA2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DMRTA2
    Sirion Biotech Customized adenovirus for overexpression of DMRTA2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for DMRTA2 (see all 7)
    OriGene ORF clones in mouse, rat for DMRTA2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DMRTA2 (NM_032110)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DMRTA2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DMRTA2
    Sirion Biotech Customized lentivirus for stable overexpression of DMRTA2 
                         Customized lentivirus expression plasmids for stable overexpression of DMRTA2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for DMRTA2
    Search LifeMap BioReagents cell lines for DMRTA2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DMRTA2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DMRTA2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/14 Interacting proteins for DMRTA2 (ENSP000003839094) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL4ENSP000003495944STRING: ENSP00000349594
    C1orf53ENSP000003563634STRING: ENSP00000356363
    CELA3BENSP000003383694STRING: ENSP00000338369
    ENSG00000206408ENSP000003829994STRING: ENSP00000382999
    ENSG00000206457ENSP000003832634STRING: ENSP00000383263
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0007548sex differentiation ----
    GO:0035914skeletal muscle cell differentiation IEA--

    DMRTA2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DMRTA2 (DMTA2)

    Search CenterWatch for drugs/clinical trials and news about DMRTA2 / DMTA2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DMRTA2 gene: 
    NM_032110.2  

    Unigene Cluster for DMRTA2:

    DMRT-like family A2
    Hs.334481  [show with all ESTs]
    Unigene Representative Sequence: NM_032110
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000418121(uc010ona.2) ENST00000404795(uc010onb.2)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DMRTA2
    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate DMRTA2 (see all 41):
    hsa-miR-106a hsa-miR-519a hsa-miR-3161 hsa-miR-374c hsa-miR-1273d hsa-miR-149 hsa-miR-93 hsa-miR-520g
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DMRTA2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DMRTA2
    Clone
    Products:
         
    OriGene clones in human, mouse for DMRTA2 (see all 7)
    OriGene ORF clones in mouse, rat for DMRTA2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DMRTA2 (NM_032110)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DMRTA2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DMRTA2
    Sirion Biotech Customized lentivirus for stable overexpression of DMRTA2 
                         Customized lentivirus expression plasmids for stable overexpression of DMRTA2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for DMRTA2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DMRTA2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DMRTA2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DMRTA2

    Additional mRNA sequence: 

    AJ301580.1 BC136282.1 BC143800.1 

    2 DOTS entries:

    DT.95193645  DT.97804738 

    11 AceView cDNA sequences:

    BQ941189 BG056274 BM560708 AI492131 BE540441 BU727085 AJ301580 BM931712 
    BE294804 BM726531 BM688501 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DMRTA2 expression in normal human tissues (normalized intensities)      DMRTA2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTTTCCTTG
    DMRTA2 Expression
    About this image


    DMRTA2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/15 selected tissues (see all 15) fully expand
     
     Brain (Nervous System)    fully expand to see all 13 entries
             Adult Oligodendrocyte Precursor Cells Lateral Ventricle
             Cerebral Cortex
             Midbrain dopaminergic-like neurons ( Generation of midbrain dopaminergic, forebrain...
             ganglion/cranial   
     
     Neural Tube (Nervous System)    fully expand to see all 6 entries
             Meso-diencephalic Dopaminergic Precursor Cells Mesencephalic Ventricular Zone
             Metencephalon
     
     Lower Urinary Tract (Urinary System)    fully expand to see all 2 entries
             visceral organ   
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             limb/hindlimb   
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   

    See DMRTA2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DMRTA2

    SOURCE GeneReport for Unigene cluster: Hs.334481

    UniProtKB/Swiss-Prot: DMTA2_HUMAN, Q96SC8
    Tissue specificity: Expressed in testis

        SABiosciences Custom PCR Arrays for DMRTA2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for DMRTA2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DMRTA2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DMRTA2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DMRTA2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DMRTA2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DMRTA2 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dmrta21 , 5 doublesex and mab-3 related transcription factor like more1, 5 87.82(n)1
    94.92(a)1
      4 (51.37 cM)5
    2426201  NM_172296.21  NP_758500.21 
     1099780535 
    lizard
    (Anolis carolinensis)
    Reptilia DMRTA26
    Uncharacterized protein
    62(a)
    1 ↔ 1
    4(113497050-113503259)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.142152 Transcribed sequence with weak similarity to protein more 73.87(n)    137725954 
    zebrafish
    (Danio rerio)
    Actinopterygii dmrta21 doublesex and mab-3 related transcription factor like more 66.36(n)
    68.49(a)
      474350  NM_001007064.2  NP_001007065.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta dmrt99B6
    doublesex-Mab related 99B
    27(a)
    1 → many
    3R(25518313-25522747)
    worm
    (Caenorhabditis elegans)
    Secernentea dmd-56
    Protein DMD-5
    30(a)
    1 → many
    II(5772065-5774220)


    ENSEMBL Gene Tree for DMRTA2 (if available)
    TreeFam Gene Tree for DMRTA2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DMRTA2 gene
    DMRT22  DMRT32  DMRT12  DMRTA12  DMRTB12  
    2 SIMAP similar genes for DMRTA2 using alignment to 3 protein entries:     DMTA2_HUMAN (see all proteins):
    DMRT2    DMRTA1

    DMRTA2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/137 SNPs in DMRTA2 are shown (see all 137)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1478224651,2
    --50882776(+) CCCTGC/TCCAGC 1 -- ds50010--------
    rs1903649811,2
    C--50882793(+) CTTCGC/TTGCCT 1 -- ds50010--------
    rs1810440711,2
    --50883005(+) GTCGCC/GGGTCC 1 -- ds50010--------
    rs1413662421,2
    --50883436(+) CTTAGA/GGACAG 1 -- ut310--------
    rs2012875231,2
    --50883798(+) AAACT-/TGTTTCC 1 -- ut310--------
    rs2016998771,2
    C--50883805(+) TTTCC-/TTTTTTT 1 -- ut311Minor allele frequency- TT:0.00CSA 2
    rs1512795311,2
    C--50884055(+) GCCTTC/TTGGAA 1 -- ut310--------
    rs29825861,2
    C--50884092(-) ACCTCC/TGGATC 1 -- ut31 ese30--------
    rs101591751,2
    C,F--50884126(+) CACCCC/ACTCCG 1 -- ut31 ese31Minor allele frequency- A:0.09WA 118
    rs1436940441,2
    C--50884159(+) CTGCT-/CCCCCC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DMRTA2 (50883222 - 50889172 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for DMRTA2: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DMRTA2
    DNA2.0 Custom Variant and Variant Library Synthesis for DMRTA2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DMRTA2 for disorders           About MalaCards
    OMIM gene information: 614804    OMIM disorders: --


    DMRTA2 for disorders           About GeneDecksing


    Export disorders for DMRTA2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DMRTA2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with DMRTA2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination. (PubMed id 11863363)1, 2, 3 Ottolenghi C.... McElreavey K. (2002)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    4. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 63950 HGNC: 13908 AceView: DMRTA2 Ensembl:ENSG00000142700 euGenes: HUgn63950
    ECgene: DMRTA2 H-InvDB: DMRTA2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DMRTA2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DMRTA2 gene:
    Search GeneIP for patents involving DMRTA2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for DMRTA2  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for DMRTA2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for DMRTA2  
     OriGene qSTAR qPCR primer pairs in human, mouse for DMRTA2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for DMRTA2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for DMRTA2   OriGene Custom Protein Services for DMRTA2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DMRTA2
     QIAGEN SeqTarget long-range PCR primers for resequencing DMRTA2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DMRTA2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DMRTA2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DMRTA2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DMRTA2
     GenScript Custom Purified and Recombinant Proteins Services for DMRTA2 GenScript cDNA clones with any tag delivered in your preferred vector for DMRTA2
     GenScript Custom Assay Services for DMRTA2 GenScript Custom Superior Antibodies Services for DMRTA2
     GenScript Custom overexpressing Cell Line Services for DMRTA2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in DMRTA2 promoter
     Search Chromatin IP Primers for DMRTA2
     RT2 qPCR Primer Assay in human, mouse, rat DMRTA2
     Search GNC Networks for DMRTA2
     SABiosciences Custom PCR Arrays for DMRTA2
     Search Tocris compounds for DMRTA2 (DMTA2)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     DMRTA2 antibodies
     Antibodies for DMRTA2
     See all of Abcam's Antibodies, Kits and Proteins for DMRTA2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for DMRTA2
     Antibodies for DMRTA2
     ELISAs for DMRTA2
     CLIAs for DMRTA2
     Search LifeMap BioReagents cell lines for DMRTA2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DMRTA2
     Browse SwitchGear 3'UTR luciferase reporter plasmids for DMRTA2
     Browse SwitchGear Promoter luciferase reporter plasmids for DMRTA2
     ThermoFisher Antibodies for DMRTA2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DMRTA2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for DMRTA2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DMRTA2
    Customized:
     lentivirus for stable overexpression of DMRTA2
     lentivirus expression plasmids for stable overexpression of DMRTA2
     adenovirus for overexpression of DMRTA2
     LSBio Antibodies in human, mouse, rat for DMRTA2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      DMRTA2 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4