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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DMKN Gene

protein-coding GIFtS: 43
GCID: GC19M035988

dermokine

Search for DMKN
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Dermokine¹
ZD52F10¹ ²
Epidermis-Specific Secreted Protein SK30/SK89² ³
UNQ729²

External Ids:	HGNC: 25063¹	Entrez Gene: 93099²	Ensembl: ENSG00000161249⁷	UniProtKB: Q6E0U4³

ORGUL members:
	NONCODE:n409370

Export aliases for DMKN gene to outside databases

Previous GC identifers: GC19M040680 GC19M032493

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DMKN:

This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers

of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate

isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding

different isoforms have been identified for this gene. (provided by RefSeq, Jun 2010)

UniProtKB/Swiss-Prot: DMKN_HUMAN, Q6E0U4

Function: May act as a soluble regulator of keratinocyte differentiation (Potential)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DMKN gene promoter:
PPAR-gamma1 C/EBPbeta POU3F1 Brachyury PPAR-gamma2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DMKN promoter sequence

Search SABiosciences Chromatin IP Primers for DMKN

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DMKN

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.12 Ensembl cytogenetic band: 19q13.12 HGNC cytogenetic band: 19q13.12

DMKN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DMKN gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M035988: view genomic region (about GC identifiers)

Start:	35,988,119 bp from pter	End:	36,004,560 bp from pter
Size:	16,442 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DMKN_HUMAN, Q6E0U4 (See protein sequence)

Recommended Name: Dermokine precursor

Size: 476 amino acids; 47082 Da

Subunit: Homooligomer. Seems to be able to homodimerize and homotrimerize

Subcellular location: Secreted

Sequence caution: Sequence=AAX48757.1; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for DMKN:

4F20 (3D)

Secondary accessions: A3EZ79 A3EZ80 A3EZ81 A3EZ82 A3EZ83 C9J5N8 C9JAL3 Q32W58 Q32W62 Q32W63 Q32W64

Q32W65 Q32W66 Q32W67 Q6E0U5 Q6UXC7 Q96EW8 Q9BSY6

Alternative splicing: 15 isoforms: Q6E0U4-1 Q6E0U4-2 Q6E0U4-3 Q6E0U4-4 Q6E0U4-5 Q6E0U4-6 Q6E0U4-7 Q6E0U4-8

Q6E0U4-9 Q6E0U4-10 Q6E0U4-11 Q6E0U4-12 Q6E0U4-13 Q6E0U4-14 Q6E0U4-15 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DMKN: NX_Q6E0U4

Post-translational modifications:

O-glycosylated¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6E0U4

DMKN Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (9 alternative transcripts):

NP_001030593.1 NP_001119528.2 NP_001119529.2 NP_001119530.2 NP_001119531.1 NP_001177276.1 NP_001177277.1 NP_001177278.1

NP_201574.3

ENSEMBL proteins:

ENSP00000386225 ENSP00000388378 ENSP00000384509 ENSP00000342012 ENSP00000412075

ENSP00000392222 ENSP00000405503 ENSP00000391036 ENSP00000398405 ENSP00000406864

ENSP00000394908 ENSP00000376042 ENSP00000403957 ENSP00000414743 ENSP00000388404

ENSP00000409513 ENSP00000397005 ENSP00000415277

Human Recombinant Protein Products:

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	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for DMKN

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005615	extracellular space	IEA	--

DMKN for ontologies About GeneDecksing

DMKN Antibody Products:

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	ThermoFisher Antibodies for DMKN

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	Uscn ELISAs and CLIAs for DMKN

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q6E0U4

UniProtKB/Swiss-Prot: DMKN_HUMAN, Q6E0U4

Similarity: Belongs to the dermokine family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: DMKN_HUMAN, Q6E0U4

Function: May act as a soluble regulator of keratinocyte differentiation (Potential)

miRNA Products:		OriGene 3'-UTR Clone (see all 7): DMKN Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DMKN
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate DMKN:
		hsa-miR-3151 hsa-miR-486-3p hsa-miR-3692
		SwitchGear 3'UTR luciferase reporter plasmid: DMKN 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DMKN (see all 4) OriGene shRNA RFP: DMKN OriGene siRNA: DMKN
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for DMKN

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DMKN

1 GenomeRNAi human phenotype for DMKN:

Increased HPV18 LCR reporter a

Animal Models:
Mouse knock-out Dmkn^tm1Lex for DMKN
1 MGI phenotypic allele

for Dmkn (no phenotypes)

DMKN for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DMKN

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for DMKN (ENSP00000342012⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DMKN
Search CenterWatch for drugs/clinical trials and news about DMKN

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DMKN gene (9 alternative transcripts):

NM_001035516.3 NM_001126056.2 NM_001126057.2 NM_001126058.2 NM_001126059.2 NM_001190347.1 NM_001190348.1 NM_001190349.1

NM_033317.4

Unigene Cluster for DMKN:

Dermokine

Hs.417795 [show with all ESTs]

Unigene Representative Sequence: BC035311

18/63 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 63):

ENST00000472252 ENST00000408915(uc002nzi.4) ENST00000460327 ENST00000434389(uc002nzj.3)

ENST00000402589 ENST00000462721 ENST00000339686(uc002nzo.4 uc002nzn.4 uc002nzm.4)

ENST00000488762 ENST00000490622(uc002nzl.4 uc002nzk.4 uc002nzu.2 uc010xsw.2 uc010xsv.1)

ENST00000436012 ENST00000467532 ENST00000472365 ENST00000414866 ENST00000480502

ENST00000469960 ENST00000467637 ENST00000484064 ENST00000478648

miRNA Products:		OriGene 3'-UTR Clone (see all 7): DMKN Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DMKN
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate DMKN:
		hsa-miR-3151 hsa-miR-486-3p hsa-miR-3692
		SwitchGear 3'UTR luciferase reporter plasmid: DMKN 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DMKN (see all 4) OriGene shRNA RFP: DMKN OriGene siRNA: DMKN
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DMKN

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DMKN

Additional cDNA sequence:

AF086315.1 AK304668.1 AK316475.1 AL832080.1 AY358412.1 AY622964.1 AY622965.1 AY789695.1

AY789696.1 AY789697.1 AY789698.1 AY789699.1 AY789700.1 AY789701.1 AY789702.1 AY789703.1

AY789704.1 AY789705.1 AY789706.1 AY789707.1 BC004493.2 BC011886.2 BC035311.1 EF158319.1

EF158320.1 EF158321.1 EF158322.1 EF158323.1 EF158324.1 EF158325.1 EF158326.1 NR_033746.1

24/42 DOTS entries (see all 42):

DT.91751126 DT.91751118 DT.95324780 DT.75155907 DT.95180791 DT.121430460 DT.100795399 DT.100027026

DT.121430469 DT.91751121 DT.40130997 DT.95180785 DT.102827719 DT.121430457 DT.40278777 DT.100784752

DT.121430435 DT.95180784 DT.100020350 DT.216664 DT.435494 DT.95086991 DT.97771032 DT.97776308

24/193 AceView cDNA sequences (see all 193):

AA683607 AI288161 AA385464 CK903380 AI240970 BM714383 AI161236 BU684200

AA854719 BM557961 AI914430 AA897755 BU788071 AI144221 AA025788 AK125695

AI127118 AI217041 AF086315 AA369873 CB321833 AY622965 BC035311 BU631488

GeneLoc Exon Structure

5/33 Alternative Splicing Database (ASD) splice patterns (SP) for DMKN (see all 33) About this scheme

ExUns:	1	^	2	^	3a	·	3b	·	3c	·	3d	·	3e	^	4a	·	4b	^	5	^	6a	·	6b	^	7a	·	7b	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13a	·	13b	^	14	^	15	^	16	^	17a	·
SP1:																							-		-		-		-		-		-		-						-		-						-
SP2:																							-		-						-		-		-						-		-						-
SP3:																							-		-		-		-		-		-		-						-		-						-
SP4:																	-						-		-				-				-								-		-						-
SP5:																	-						-		-		-		-		-		-		-						-		-						-

ExUns:	17b	·	17c	^	18a	·	18b	·	18c	^	19a	·	19b	^	20a	·	20b	^	21a	·	21b	·	21c	^	22	^	23a	·	23b	·	23c	·	23d
SP1:			-				-		-						-						-		-		-
SP2:			-				-		-						-						-		-		-
SP3:			-		-		-		-						-						-		-		-
SP4:			-		-		-		-
SP5:			-				-		-

ECgene alternative splicing isoforms for DMKN

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DMKN expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATCTTGTTT

About this image

DMKN expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)

Intermediate Mesoderm, Kidney

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DMKN Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DMKN

SOURCE GeneReport for Unigene cluster: Hs.417795

UniProtKB/Swiss-Prot: DMKN_HUMAN, Q6E0U4

Tissue specificity: Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the

epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed

in epidermis and placenta. Isoform 1 is expressed in epidermis

SABiosciences Custom PCR Arrays for DMKN

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DMKN

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for DMKN gene from 2/4 species (see all 4) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Dmkn⁵	dermokine	--		7 (19.24 cM) 30763756
worm (Caenorhabditis elegans)	Secernentea	H12D21.6⁶	Protein H12D21.6	26(a)	1 ↔ 1	V(14897269-14897816)

ENSEMBL Gene Tree for DMKN (if available)
TreeFam Gene Tree for DMKN (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DMKN gene

LOR²

DMKN for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs34431859^1,2	C	--	32493472(+)	`GAGGCA/CCAATG`	3	--	ds500¹		1		NA	2
rs16970417^1,2	C,F,H,	--	32493820(+)	`AACAAG/AGAGAG`	3	--	ut3¹ nc-transcript-variantese³		5		NS NA	506
rs76462199^1,2		--	32493915(+)	`CCTGAC/TGACCA`	3	--	nc-transcript-variantut3¹		2		CSA WA	120
rs73928209^1,2	C,F,	--	32493920(+)	`CGACCA/G/TGTGCT`	6	--	ut3¹ nc-transcript-variant		3		WA CSA	121
rs111793666^1,2	C,	--	32494149(+)	`TCTCGC/TCCATG`	3	--	int¹		1		NA	2
rs73043065^1,2	C,	--	32494207(+)	`TTCTCC/TACAGT`	3	--	int¹		0	--	--	--	--
rs77746367^1,2	C,F,	--	32494227(+)	`ACATCT/ACTATC`	3	--	int¹		1		WA	118
rs11880364^1,2	C,F,H,	--	32494313(+)	`GAGGGT/CCCTAG`	3	--	int¹		18		NS EA NA WA CSA	1699
rs113741885^1,2	C,	--	32494364(+)	`CTCTT-/TCTCTCT`	3	--	int¹		1		CSA	2
rs35007531^1,2	C,F,	--	32494615(+)	`GCAGCG/AGTGCA`	3	--	int¹		4		NA	12

HapMap Linkage Disequilibrium report for DMKN (35988119 - 36004560 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DMKN: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DMKN

DNA2.0 Custom Variant and Variant Library Synthesis for DMKN

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DMKN gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with DMKN)

Utopia: connect your pdf to the dynamic
world of online information

The human dermokine gene: description of novel isoforms with different tissue-specific expression and subcellular location. (PubMed id 16374476)^{1, 2, 3} Toulza E.... Guerrin M. (2006)
Dermokine: an extensively differentially spliced gene expressed in epithelial cells. (PubMed id 17380110)^{1, 2} Naso M.F.... Amegadzie B.Y. (2007)
Identification of novel keratinocyte-secreted peptides dermokine- alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1. (PubMed id 15234001)^{1, 2} Matsui T.... Tsukita S. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Dermokine expression in intraductal papillary-mucinous neoplasm and invasive pancreatic carcinoma. (PubMed id 23060565)¹ Watanabe K....Otsuji E. (2012)
Dermokine-b impairs ERK signaling through direct bindi ng to GRP78. (PubMed id 22735594)¹ Higashi K....Saito K. (2012)
The ubiquitous dermokine delta activates Rab5 functio n in the early endocytic pathway. (PubMed id 21423773)¹ Leclerc E.A....Jonca N. (2011)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 93099	HGNC: 25063	AceView: ZD52F10	Ensembl:ENSG00000161249	euGenes: HUgn93099
ECgene: DMKN	H-InvDB: DMKN

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DMKN	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DMKN gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DMKN gene:
Search GeneIP for patents involving DMKN

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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