Aliases for DMC1 Gene
Aliases for DMC1 Gene
- DNA Meiotic Recombinase 1 2 3 5
- DMC1H 3 4
- LIM15 3 4
- DMC1 (Dosage Suppressor Of Mck1, Yeast Homolog) Meiosis-Specific Homologous Recombination 2
- DMC1 Dosage Suppressor Of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) 2
- DMC1 Dosage Suppressor Of Mck1 Homolog, Meiosis-Specific Homologous Recombination 3
- Meiotic Recombination Protein DMC1/LIM15 Homolog 3
- Disrupted Meiotic CDNA1, Yeast, Homolog Of 3
- DJ199H16.1 3
External Ids for DMC1 Gene
- HGNC: 2927
- Entrez Gene: 11144
- Ensembl: ENSG00000100206
- OMIM: 602721
- UniProtKB: Q14565
Previous GeneCards Identifiers for DMC1 Gene
- GC22M035529
- GC22M037157
- GC22M037239
- GC22M038914
- GC22M021880
- GC22M038518
- GC22M038622
- GC22M038814
- GC22M039934
- GC22M040622
Summaries for DMC1 Gene
-
This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
GeneCards Summary for DMC1 Gene
DMC1 (DNA Meiotic Recombinase 1) is a Protein Coding gene. Among its related pathways are Meiosis and Cell Cycle, Mitotic. GO annotations related to this gene include nucleotide binding and DNA-dependent ATPase activity.
UniProtKB/Swiss-Prot for DMC1 Gene
-
May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DMC1 Gene
Genomics for DMC1 Gene
Regulatory Elements for DMC1 Gene
Enhancers for DMC1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around DMC1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the DMC1 gene promoter:
Regulatory Element Products
Genomic Location for DMC1 Gene
- Chromosome:
- 22
- Start:
- 38,509,154 bp from pter
- End:
- 38,570,286 bp from pter
- Size:
- 61,133 bases
- Orientation:
- Minus strand
Genomic View for DMC1 Gene
Genes around DMC1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q13.1 by Ensembl
- 22q13.1 by Entrez Gene
- 22q13.1 by HGNC
DMC1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DMC1 Gene
Proteins for DMC1 Gene
-
Protein details for DMC1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14565-DMC1_HUMAN
- Recommended name:
- Meiotic recombination protein DMC1/LIM15 homolog
- Protein Accession:
- Q14565
- A8K9A2
- B4DMW6
- Q08AI1
- Q99498
- Q9UH11
Protein attributes for DMC1 Gene
- Size:
- 340 amino acids
- Molecular mass:
- 37681 Da
- Quaternary structure:
-
- Interacts with the MND1-PSMC3IP heterodimer (By similarity). Double stacked ring-shaped homooctamer. Interacts with BRCA2.
Protein Expression for DMC1 Gene
Post-translational modifications for DMC1 Gene
Other Protein References for DMC1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for DMC1
- Invitrogen Antibodies for DMC1
- antibodies-online Antibodies for DMC1: See all 71
- GeneTex DMC1 antibody for DMC1
-
Santa Cruz Biotechnology (SCBT) Antibodies for DMC1
Protein Products
-
OriGene Purified Proteins for DMC1
- Search Origene for MassSpec and Protein Over-expression Lysates for DMC1
- Origene Custom Protein Services for DMC1
- antibodies-online Proteins for DMC1: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for DMC1
Assay Products
- antibodies-online Kits for DMC1: See all 3
No data available for DME Specific Peptides for DMC1 Gene
Domains & Families for DMC1 Gene
Protein Domains for DMC1 Gene
Suggested Antigen Peptide Sequences for DMC1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q14565- Family:
-
- Belongs to the RecA family. DMC1 subfamily.
No data available for Gene Families for DMC1 Gene
Function for DMC1 Gene
Molecular function for DMC1 Gene
- GENATLAS Biochemistry:
- DMC1,dosage suppressor of MCK1,S cerevisiae homolog,E Coli Rec-A like gene,forming mixed complexes with RAD51 associated with mouse meiotic chromosomes core and synaptonemal complexes,meiosis-specific homologous recombination gene
- UniProtKB/Swiss-Prot Function:
- May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000150 | recombinase activity | IBA | -- |
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0000400 | four-way junction DNA binding | IBA | -- |
| GO:0003677 | DNA binding | IEA,TAS | 8602360 |
| GO:0003690 | double-stranded DNA binding | IBA | -- |
Phenotypes for DMC1 Gene
- MGI mutant phenotypes for DMC1:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for DMC1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for DMC1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for DMC1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DMC1 gene
- Search ViGene Biosciences for DMC1
CRISPR Products
-
OriGene CRISPR knockouts for DMC1
-
Santa Cruz Biotechnology (SCBT) CRISPR for DMC1
- GenScript: Design CRISPR guide RNA sequences for DMC1
Targeted motifs for DMC1 Gene
HOMER Transcription Factor Regulatory Elements motif DMC1
- Consensus sequence: ACTYKNATTCGTGNTACTTC Submotif: canonical Cell Type: Testis GEO ID: GSE24438
miRNA Products
- Search ViGene Biosciences for DMC1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for DMC1
- Browse OriGene Inhibitory RNA Products For DMC1
-
ViGene Biosciences ready-to-package AAV shRNAs for DMC1 gene
Clone Products
- Sino Biological Human cDNA Clone for DMC1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DMC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DMC1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for DMC1
-
ViGene Biosciences adenoviral particle packaged cDNA for DMC1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for DMC1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DMC1 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA and Transcription Factor Targets for DMC1 Gene
Localization for DMC1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DMC1 Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000781 | chromosome, telomeric region | IEA | -- |
| GO:0000794 | condensed nuclear chromosome | IBA,TAS | -- |
| GO:0005634 | nucleus | IDA | 22899867 |
| GO:0005654 | nucleoplasm | IBA | -- |
| GO:0005694 | chromosome | ISS | -- |
Pathways & Interactions for DMC1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Meiosis |
.73
|
|
| 2 | Cell Cycle, Mitotic |
.83
|
|
| 3 | Ovarian Infertility Genes | ||
Pathways by source for DMC1 Gene
1 BioSystems pathway for DMC1 Gene
3 Reactome pathways for DMC1 Gene
Interacting Proteins for DMC1 Gene
Selected Interacting proteins:
Q14565-DMC1_HUMAN
ENSP00000216024
for DMC1 Gene via
MINT
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000730 | DNA recombinase assembly | IBA | -- |
| GO:0001541 | ovarian follicle development | IEA | -- |
| GO:0001556 | oocyte maturation | IEA | -- |
| GO:0006259 | DNA metabolic process | IEA | -- |
| GO:0006281 | DNA repair | IEA | -- |
No data available for SIGNOR curated interactions for DMC1 Gene
Transcripts for DMC1 Gene
mRNA/cDNA for DMC1 Gene
- (8) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (17) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for DMC1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for DMC1
-
Santa Cruz Biotechnology (SCBT) CRISPR for DMC1
- GenScript: Design CRISPR guide RNA sequences for DMC1
miRNA Products
- Search ViGene Biosciences for DMC1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for DMC1
- Browse OriGene Inhibitory RNA Products For DMC1
-
ViGene Biosciences ready-to-package AAV shRNAs for DMC1 gene
Clone Products
- Sino Biological Human cDNA Clone for DMC1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DMC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DMC1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for DMC1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Gonad
- Primary Oocyte Primordial Follicle
- Primordial Germ Cells Primitive Gonad
- Primary Spermatocyte Seminiferous Tubules
- XX Germ Cells Ovigerous Cord
- Germ-like cells(Panula S et. al. 2011)
-
Ovary (Reproductive System)
- Primary Oocyte Primordial Follicle
- XX Germ Cells Ovigerous Cord
- Ovarian tissue-dissociated cells (human)
- Oocytes(White YA et. al. 2012)
-
Testis (Reproductive System)
- Primary Spermatocyte Seminiferous Tubules
- testis ; cells in seminiferous ducts
- Germ Cells (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for DMC1 Gene
This gene is overexpressed in Testis (x13.9).
This gene is overexpressed in Ovary (28.2), Fetal ovary (26.8), and Testis (14.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for DMC1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of DMC1 Gene:
DMC1SOURCE GeneReport for Unigene cluster for DMC1 Gene:
Hs.339396Evidence on tissue expression from TISSUES for DMC1 Gene
- Heart(4.1)
Primer Products
-
OriGene qPCR primer pairs for DMC1
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DMC1 Gene
Orthologs for DMC1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | DMC1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | DMC1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | DMC1 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | DMC1 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Dmc1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Dmc1 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | DMC1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | DMC1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | DMC1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | dmc1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | dmc1 34 35 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F11957g 34 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | DMC1 34 35 37 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AGR101C 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | DMC1 34 |
|
||
| soybean (Glycine max) |
eudicotyledons | Gma.8429 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os12g0143800 34 |
|
||
| barley (Hordeum vulgare) |
Liliopsida | Hv.2446 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne | |
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | dmc1 34 |
|
- Species where no ortholog for DMC1 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for DMC1 Gene
(1) SIMAP similar genes for DMC1 Gene using alignment to 5 proteins:
No data available for Paralogs for DMC1 Gene
Variants for DMC1 Gene
| SNP ID | Clin | Chr 22 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000021132 | -- | 38,558,809(+) | AATAA(C/T)AGTAA | intron-variant | |
| rs1000026804 | -- | 38,544,478(+) | GACTG(A/G)ACCAA | intron-variant | |
| rs1000097479 | -- | 38,552,183(+) | CACTT(G/T)GCCAA | intron-variant | |
| rs1000099582 | -- | 38,518,381(+) | AACTA(A/G)TGTAC | intron-variant | |
| rs1000132675 | -- | 38,509,007(+) | ATACG(C/T)CACCA | downstream-variant-500B |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1003190 | OTHER | inversion | 20482838 |
| esv28829 | CNV | loss | 19812545 |
| esv3647737 | CNV | loss | 21293372 |
| nsv1131658 | CNV | deletion | 24896259 |
| nsv1136678 | CNV | deletion | 24896259 |
| nsv3624 | CNV | deletion | 18451855 |
Residual Variation Intolerance Score:
24.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.06;
60.72% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for DMC1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DMC1 Gene
Disorders for DMC1 Gene
Relevant External Links for DMC1
No disorders were found for DMC1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DMC1 Gene
Publications for DMC1 Gene
- The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon- skipped transcript in meiosis. (PMID: 8602360) Habu T. … Morita T. (Nucleic Acids Res. 1996) 2 3 4 22 64
- Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1. (PMID: 17541404) Thorslund T. … West S.C. (EMBO J. 2007) 2 3 22 64
- Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein Dmc1. (PMID: 15125839) Kinebuchi T. … Yokoyama S. (Mol. Cell 2004) 3 4 22 64
- Expression profiles of a human gene identified as a structural homologue of meiosis-specific recA-like genes. (PMID: 8590282) Sato S. … Tabata S. (DNA Res. 1995) 2 3 4 64
- Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent. (PMID: 20378615) Aston K.I. … Carrell D.T. (Hum. Reprod. 2010) 3 46 64
Products for DMC1 Gene
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- Custom Antibody ServicesOriGene Antibodies for DMC1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for DMC1
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for DMC1
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- OriGene qPCR primer pairs for DMC1
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- GenScript: Next-day shipping cDNA ORF clone for DMC1 in any vector
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- GenScript Custom overexpressing Cell Line Services for DMC1
- GenScript: Design CRISPR guide RNA sequences for DMC1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for DMC1
- Novus Biologicals proteins and lysates for DMC1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for DMC1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for DMC1: See all 71
- antibodies-online Kits for DMC1: See all 3
- antibodies-online Proteins for DMC1: See all 4
- Search antibodies-online for peptides
- GeneTex DMC1 antibody for DMC1
- Search GeneTex for Proteins for DMC1
- ViGene Biosciences adenoviral particle packaged cDNA for DMC1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for DMC1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for DMC1 gene
- Search ViGene Biosciences for DMC1
- Santa Cruz Biotechnology (SCBT) Antibodies for DMC1
- Search Santa Cruz Biotechnology (SCBT) for DMC1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for DMC1
- Horizon Cell Lines for DMC1
- Cyagen custom Knockout/knockin (KOKI) mouse models for DMC1
- VectorBuilder custom plasmid, inducible vectors for DMC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DMC1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for DMC1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer