DMAP1 Gene
protein-coding GIFtS: 54
GCID: GC01P044680
|
|
DNA methyltransferase 1 associated protein 1
| |
Aliases for DMAP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| DNA Methyltransferase 1 Associated Protein 11 2 | | KIAA14251 3 | | DNMAP11 2 3 | | DNMT1-Associated Protein 12 3 | | DNMTAP11 2 | | FLJ115431 | | EAF21 2 | | DNA Methyltransferase 1-Associated Protein 12 | | MEAF21 2 | | DNMT1 Associated Protein 12 | | SWC41 2 | | |
Export aliases for DMAP1 gene to outside databasesPrevious GC identifers: GC01U990334 GC01P043680 GC01P044108 GC01P044092 GC01P044348 GC01P044451 GC01P042792 |
Summaries for DMAP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for DMAP1: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription.The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase byinteracting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 isadded to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatinfollowing replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex andinteracts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associatedprotein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.(provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: DMAP1_HUMAN, Q9NPF5Function: Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism forhistone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also represstranscription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression ofglucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex whichis involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 andH2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histoneswith other proteins which positively regulate transcription. This complex may be required for the activation oftranscriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressormediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNArepair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases itstranscriptional corepressor activity Gene Wiki entry for DMAP1
|
Genomic Views for DMAP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DMAP1 gene promoter: N-Myc CREB AML1a Pax-5 deltaCREB ATF c-Ets-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for DMAP1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DMAP1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p34 Ensembl cytogenetic band: 1p34.1 HGNC cytogenetic band: 1p34DMAP1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P044680: view genomic region
(about GC identifiers)
Start:
|
44,679,125 bp from pter |
End:
|
44,686,353 bp from pter |
Size:
|
7,229 bases |
Orientation:
|
plus strand |
|
Proteins for DMAP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: DMAP1_HUMAN, Q9NPF5 (See
protein sequence)Recommended Name: DNA methyltransferase 1-associated protein 1 Size: 467 amino acids; 52993 Da
Subunit: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 andthe subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A,MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6. Component of a NuA4-related complex whichcontains EP400, TRRAP/PAF400, SRCAP, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, actin, ACTL6A/BAF53A, VPS72and YEATS4/GAS41. DMAP1 also forms a complex with DNMT1 and HDAC2. Throughout S phase it interacts directly with theN-terminus of DNMT1, which serves to recruit DMAP1 to replication foci. DMAP1 interacts with ING1, a component of themSin3A transcription repressor complex, although this interaction is not required for recruitment of ING1 toheterochromatin. Interacts directly with the transcriptional corepressor TSG101. Interacts with the pro-apoptoticprotein DAXX. Interacts with URI1
Subcellular location: Nucleus. Cytoplasm. Note=Targeted to replication foci throughout S phase by DNMT1
Sequence caution: Sequence=BAA92663.1; Type=Erroneous initiation;
2 PDB 3D structures from and Proteopedia for DMAP1:3HM5 (3D)
  4IEJ (3D)
 
Secondary accessions: A8K001 D3DPY8 Q0JSM4 Q5TG41 Q7Z3H7 Q9H0S8 Q9P2C2Explore the universe of human proteins at neXtProt for DMAP1: NX_Q9NPF5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NPF5 DMAP1 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (3 alternative transcripts):
NP_001029195.1 NP_001029196.1 NP_061973.1 ENSEMBL proteins: ENSP00000354697 ENSP00000409200 ENSP00000401099 ENSP00000400269 ENSP00000402494 ENSP00000312697 ENSP00000361363 ENSP00000361364 Human Recombinant Protein Products for DMAP1:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
DMAP1 for ontologies About GeneDecksing
DMAP1 Antibody Products: Assay Products for DMAP1: |
Protein
Domains / Families for DMAP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DMAP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NPF5ProtoNet protein and cluster: Q9NPF5 1 Blocks protein family: IPB001005 Myb DNA-binding domain
UniProtKB/Swiss-Prot: DMAP1_HUMAN, Q9NPF5Similarity: Contains 1 SANT domain |
Function for DMAP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: DMAP1_HUMAN, Q9NPF5Function: Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism forhistone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also represstranscription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression ofglucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex whichis involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 andH2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histoneswith other proteins which positively regulate transcription. This complex may be required for the activation oftranscriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressormediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNArepair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases itstranscriptional corepressor activity Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
DMAP1 for ontologies About GeneDecksing
Phenotypes: 5 GenomeRNAi human phenotypes for DMAP1: 4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Dmap1):
DMAP1 for phenotypes About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DMAP1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DMAP1 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): DMAP1 (NM_019100) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DMAP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DMAP1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DMAP1 |
|
Pathways & Interactions for DMAP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DMAP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/782 Interacting proteins for DMAP1 (Q9NPF52, 3 ENSP000003126974) via UniProtKB, MINT, STRING, and/or I2D (see all 782)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
DMAP1 for ontologies About GeneDecksing
|
Drugs & Compounds for DMAP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for DMAP1 Search CenterWatch for drugs/clinical trials and news about DMAP1 
|
Transcripts for DMAP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for DMAP1 gene (3 alternative transcripts): NM_001034023.1 NM_001034024.1 NM_019100.4 Unigene Cluster for DMAP1: DNA methyltransferase 1 associated protein 1 Hs.8008 [show with all ESTs]Unigene Representative Sequence: NM_01910015 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000361745(uc001clq.1) ENST00000446292(uc010okt.1) ENST00000440641 ENST00000436069 ENST00000437511 ENST00000475794(uc010okq.1 uc010okr.1 uc010oks.1) ENST00000471829 ENST00000487922 ENST00000315913(uc001clr.1 uc010oku.1) ENST00000372289(uc001cls.1) ENST00000463950 ENST00000372290 ENST00000488433 ENST00000483741 ENST00000494092
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DMAP1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DMAP1 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): DMAP1 (NM_019100) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DMAP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DMAP1  |
Additional cDNA sequence: AB037846.1 AF265228.1 AK021605.1 AK289366.1 AK293598.1 AK298793.1 AK300217.1 AK300372.1 AK300442.1 AL136657.1 AL137200.1 BC002855.2 BC008053.2 24/27 DOTS entries (see all 27): DT.100819674 DT.100721825 DT.75179550 DT.97768073 DT.97848192 DT.95370332 DT.121437270 DT.100819682 DT.100030295 DT.121437346 DT.91758097 DT.121437332 DT.95370337 DT.121437323 DT.100819671 DT.91758088 DT.95370335 DT.100715922 DT.121437324 DT.100030296 DT.100819669 DT.121437335 DT.121437395 DT.91758090 24/347 AceView cDNA sequences (see all 347): BU147366 BC008053 BI489829 BE407233 BE275577 CD723612 BI769792 BU932104 AI168113 AI582444 F08877 BP346999 BF724094 AA378606 AI017052 BU738989 BF882198 AW840116 BI831615 AK054954 F08876 CF131098 BM264106 AW166747 GeneLoc Exon Structure
5/23 Alternative Splicing Database (ASD) splice patterns (SP) for DMAP1 (see all 23) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9 | ^ | |
| SP1: | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |
| SP2: | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |
| SP4: | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for DMAP1
|
Expression for DMAP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DMAP1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AGGCACTGGC
 About this image See DMAP1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DMAP1
SOURCE GeneReport for Unigene cluster: Hs.8008 SABiosciences Custom PCR Arrays for DMAP1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DMAP1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DMAP1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DMAP1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DMAP1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DMAP1 |
Orthologs for DMAP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DMAP1 gene from 9/30 species (see all 30) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Dmap11 , 5 |
DNA methyltransferase 1-associated protein 11, 5 |
89.44(n)1 98.07(a)1 |
  |
4 (53.46 cM)5 662331 NM_023178.21 NP_075667.11 1176746815 |
chicken (Gallus gallus) |
Aves |
DMAP11 |
DNA methyltransferase 1 associated protein 1 |
75.4(n) 86.46(a) |
  |
424578 XM_422417.3 XP_422417.3 |
lizard (Anolis carolinensis) |
Reptilia |
DMAP16 |
-- |
88(a) |
1 ↔ 1 |
4(109240308-109273969) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.32442 |
Xenopus laevis transcribed sequence with weak similarity more |
74.98(n) |
  |
CD329679.1 |
zebrafish (Danio rerio) |
Actinopterygii |
zgc555932 |
similar to DNA methyltransferase 1-associated protein more |
73.35(n) |
  |
393225 BC048054.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG111323 DMAP11 |
CG11132-PA1 |
48(a)3 56.65(n)1 53.03(a)1 |
  |
57A93 373391 NM_137659.31 NP_611503.11 |
worm (Caenorhabditis elegans) |
Secernentea |
Y105E8A.173 ekl-41 |
Protein EKL-41 |
40(a)3 49.01(n)1 42.54(a)1 |
  |
I(14477547-14484526)3 1733101 NM_001129058.11 NP_001122530.11 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT2G472101 |
DNA methyltransferase 1-associated protein 1 |
46.47(n) 37.06(a) |
  |
819334 NM_180139.3 NP_850470.1 |
rice (Oryza sativa) |
Liliopsida |
Os05g05408001 |
hypothetical protein |
43.34(n) 34.99(a) |
  |
4339468 NM_001062718.1 NP_001056183.1 |
ENSEMBL Gene Tree for DMAP1 (if available) TreeFam Gene Tree for DMAP1 (if available)  |
Paralogs for DMAP1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for DMAP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for DMAP1 (44679125 - 44686353 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for DMAP1: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DMAP1 |
|
Disorders
/ Diseases for DMAP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DMAP1 for disorders About GeneDecksing
OMIM gene information: 605077
OMIM disorders: --
10 diseases for DMAP1: About MalaCardseaf male germ cell tumor germ cell tumor transitional cell carcinoma intrahepatic cholangiocarcinoma seminoma cholangiocarcinoma pharyngitis carcinoma malaria Export disorders for DMAP1 gene to outside databases
|
Publications for DMAP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DMAP1 gene, integrated from 9 sources (see all 54): (articles sorted by number of sources associating them with DMAP1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. (PubMed id 10888872)1, 2, 3, 9 Rountree M.R.... Baylin S.B. (2000)
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (2000)
- Components of a pathway maintaining histone modification and heterochromatin protein 1 binding at the pericentric heterochromatin in Mammalian cells. (PubMed id 14665632)1, 2, 9 Xin H.... Qin J. (2004)
- Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. (PubMed id 12963728)1, 2, 9 Cai Y.... Conaway J.W. (2003)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The highly conserved and multifunctional NuA4 HAT complex. (PubMed id 15196461)1, 2 Doyon Y. and Cote J. (2004)
- Physical and functional interactions between Daxx and DNA methyltransferase 1-associated protein, DMAP1. (PubMed id 14978102)1, 2 Muromoto R.... Matsuda T. (2004)
- Subcellular localization of RPB5-mediating protein and its putative functional partner. (PubMed id 15367675)1, 2 Delgermaa L....Murakami S. (2004)
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External Searches for DMAP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing DMAP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing DMAP1 gene
(According to HUGE)
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Specialized Databases showing DMAP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
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| Name | Description |
| PharmGKB entry for DMAP1 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for DMAP1 gene: Search GeneIP for patents involving DMAP1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for DMAP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for DMAP1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DMAP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DMAP1 | | OriGene Protein Over-expression Lysate for DMAP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for DMAP1 | | OriGene 3'-UTR Clone for DMAP1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DMAP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DMAP1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for DMAP1 | | OriGene Custom Protein Services for DMAP1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DMAP1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DMAP1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DMAP1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DMAP1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DMAP1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DMAP1 |
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 | | DMAP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DMAP1 |
|  |  |  |  | | | ThermoFisher Antibody for DMAP1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DMAP1 |
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