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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DLX6-AS1 Gene

RNA gene GIFtS: 23
GCID: GC07M096595

DLX6 antisense RNA 1

(Previous names: non-protein coding RNA 212, DLX6 antisense RNA 1 (non-protein...)
(Previous symbol: NCRNA00212)

Search for DLX6-AS1
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Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 3

Aliases
DLX6 Antisense RNA 1¹ ²		DLX6 Antisense RNA 1 (Non-Protein Coding)¹
Evf-2¹ ²		Non-Protein Coding RNA 212¹
NCRNA00212¹ ²		DLX6-AS²
FLJ34048¹		DLX6AS²

External Ids:	HGNC: 37151¹	Entrez Gene: 285987²	Ensembl: ENSG00000231764⁷

ORGUL members:
	NONCODE:n385239 n341279 n346032 n386450

Export aliases for DLX6-AS1 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007933.15 NT_079595.2

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for DLX6-AS1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

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Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DLX6-AS1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21.3 Ensembl cytogenetic band: 7q21.3 HGNC cytogenetic band: 7q21.3

DLX6-AS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DLX6-AS1 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M096595: view genomic region (about GC identifiers)

Start:	96,594,839 bp from pter	End:	96,643,377 bp from pter
Size:	48,539 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 95,920,326-95,965,871

ORGUL member locations:
Legend (see complete legend)

n346032
n341279
n385239
n386450

lncRNA
Full Legend

96594574 96618976 96643377 chr7

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB: --

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DLX6-AS1

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
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(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Cluster for DLX6-AS1:

DLX6 antisense RNA 1

Hs.34969 [show with all ESTs]

Unigene Representative Sequence: AK095619

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000430027(uc003uol.3) ENST00000431497(uc003uok.3) ENST00000452769

ENST00000437331 ENST00000430404 ENST00000458352(uc010lfo.1) ENST00000437541

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Additional cDNA sequence:

AK055423.1 AK091367.1 AK095619.1 AK095764.1 AK308769.1 AK309768.1 BC101445.1 BC101446.1

BC101447.1 BC101985.1 BC113049.1 NR_015448.1

6 DOTS entries:

DT.102827510 DT.100021363 DT.92419744 DT.92419745 DT.101956849 DT.121098873

24/76 AceView cDNA sequences (see all 76):

BX463429 BQ025929 F10243 AK095764 AI089581 BE264380 BE792834 AI089583

CR602612 AA626681 AK055423 CR626626 F12627 AW245971 AW245662 BX643287

BX477952 D81276 AI830571 AX746939 D60709 T05086 AA829282 D81797

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

Expression evidence for DLX6-AS1:none

DLX6-AS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCATCTTT

About this image

DLX6-AS1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)

Heart, Myocardium, Smooth Muscle

PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Genevestigator expression for DLX6-AS1

SOURCE GeneReport for Unigene cluster: Hs.34969

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

--

ENSEMBL Gene Tree for DLX6-AS1 (if available)
TreeFam Gene Tree for DLX6-AS1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs74900827^1,2	F,	--	96597461(+)	`ATTAGT/CTGTAT`	1	--	ds500¹		1		WA	118
rs146116903^1,2		--	96597474(+)	`TTAAAC/TATGAC`	1	--	ds500¹		0	--	--	--	--
rs185833414^1,2		--	96597522(+)	`TCATGG/TCTTTA`	1	--	ds500¹		0	--	--	--	--
rs79772102^1,2	C,	--	96597542(+)	`AACCAA/GCAATG`	1	--	ds500¹		0	--	--	--	--
rs75011751^1,2	C,	--	96597543(+)	`ACCAGA/CAATGT`	1	--	ds500¹		0	--	--	--	--
rs28694374^1,2	C,F,	--	96597649(+)	`GGCAAA/GGAGTT`	1	--	ds500¹		1		WA	118
rs186117996^1,2		--	96597790(+)	`TGGAGG/TGCAGA`	1	--	ds500¹		0	--	--	--	--
rs148779890^1,2		--	96597807(+)	`ACATGC/TAGGGT`	1	--	ds500¹		0	--	--	--	--
rs141530239^1,2		--	96597848(+)	`TTGTTC/TAATCT`	1	--	nc-transcript-variant		0	--	--	--	--
rs116175616^1,2	C,	--	96598029(+)	`TGATTA/TTGCCC`	1	--	nc-transcript-variant		0	--	--	--	--

HapMap Linkage Disequilibrium report for DLX6-AS1 (96594839 - 96643377 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DLX6-AS1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DLX6-AS1

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DLX6-AS1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with DLX6-AS1)

Utopia: connect your pdf to the dynamic
world of online information

The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. (PubMed id 16705037)^{1, 3} Feng J....Kohtz J.D. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)¹ Scherer S.W.... Tsui L.-C. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 285987	HGNC: 37151	AceView: FLJ34048	Ensembl:ENSG00000231764	euGenes: HUgn285987
ECgene: DLX6-AS1	H-InvDB: DLX6-AS1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DLX6-AS1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DLX6-AS1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for DLX6-AS1 gene:
Search GeneIP for patents involving DLX6-AS1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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DLX6 antisense RNA 1

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DLX6-AS1 Gene

DLX6 antisense RNA 1

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for DLX6-AS1 gene

Orthologs
for DLX6-AS1 gene

Paralogs
for DLX6-AS1 gene

Genomic Variants
for DLX6-AS1 gene

Disorders / Diseases
for DLX6-AS1 gene

Publications
for DLX6-AS1 gene

Intellectual Property
for DLX6-AS1 gene

Products
for DLX6-AS1 gene