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DLST Gene

protein-coding GIFtS: 63

GC14P074418

dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: DLTS)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DLTS ^², ³
E2 ^³
E2K ^³
EC 2.3.1.61 ^³

Descriptions
Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex ^³
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) ^²

External Ids
HGNC: 2911¹
Entrez Gene: 1743²
UniProtKB: P36957³
Ensembl: ENSG00000119689⁷

Search outside databases for aliases for DLST gene

Previous GC identifers: GC14P072875 GC14P069166 GC14P073338

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ODO2_HUMAN, P36957

Function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of

2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components:

2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide

dehydrogenase (E3)

Gene Wiki entry for DLST

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DLST gene

Entrez Gene cytogenetic band: 14q24.3 Ensembl cytogenetic band: 14q24.3 HGNC cytogenetic band: 14q23.1

DLST Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14P074418: (about GC identifiers)

Start:	74,418,372 bp from pter
End:	74,440,199 bp from pter
Size:	21,828 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ODO2_HUMAN, P36957 (See protein sequence)

Recommended Name: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate

dehydrogenase complex, mitochondrial precursor

Size: 453 amino acids; 48729 Da

Cofactor: Binds 1 lipoyl cofactor covalently

Subunit: Forms a 24-polypeptide structural core with octahedral symmetry

Subcellular location: Mitochondrion

Secondary accessions: Q7LDY7 Q9BQ32

REFSEQ proteins: NP_001924.2

ENSEMBL proteins:

ENSP00000238671 ENSP00000335465 ENSP00000335304

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (DLST)
	Human Recombinant Proteins from Abnova (DLST)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	18029348
GO:0005737	cytoplasm	IDA	18029348
GO:0005739	mitochondrion	IEA	--
GO:0005759	mitochondrial matrix	EXP	2188967
GO:0045252	oxoglutarate dehydrogenase complex	IEA	--

About this table

Antibodies for DLST:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for DLST
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (DLST), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DLST)
	Novus Biologicals Antibodies for DLST

Assays for DLST:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P36957

ProtoNet protein and cluster: P36957

3 Blocks protein families:

IPB000089 Biotin/lipoyl attachment

IPB001078 Catalytic domain of components of various dehydrogenase complexes

IPB003016 2-oxo acid dehydrogenase

UniProtKB/Swiss-Prot: ODO2_HUMAN, P36957

Similarity: Belongs to the 2-oxoacid dehydrogenase family

Similarity: Contains 1 lipoyl-binding domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DLST)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DLST)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001933

Applied Biosystems Silencer® siRNAs for DLST

Sigma-Aldrich siRNA for DLST

Sigma-Aldrich shRNA for DLST

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DLST
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001933
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001933
untagged cDNA clone in CMV expression vector: NM_001933

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001933

UniProtKB/Swiss-Prot: ODO2_HUMAN, P36957

Function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of

2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components:

2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide

dehydrogenase (E3)

Catalytic activity: Succinyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme

N(6)-(S-succinyldihydrolipoyl)lysine

Enzyme Number (IUBMB): EC 2.3.1.61

Genatlas biochemistry entry for DLST:

dihydrolipoamide S-succinyltransferase

1 MGI phenotypic allele

for Dlst (no phenotypes)

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity	IEA	--
GO:0005515	protein binding	IPI	17220478
GO:0008415	acyltransferase activity	IEA	--
GO:0016740	transferase activity	IEA	--
GO:0031405	lipoic acid binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for DLST (Your Favorite Gene powered by Ingenuity)

Lysine Degradation
Citrate Cycle

GeneDecks DLST for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: ODO2_HUMAN, P36957

Pathway: Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from

L-lysine: step 6/6

5/68 Interacting proteins for DLST (ENSP00000335304³ P36957^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 68 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NDRG1	Q92597¹	EBI-351007, EBI-716486
A2M	P01023²	MINT-4054731
ACTB	P60709²	MINT-4054731
ALPP	P05187²	MINT-4054731
APOD	P05090²	MINT-4054731

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006091	generation of precursor metabolites and energy	TAS	8009371
GO:0006099	tricarboxylic acid cycle	IEA	--
GO:0008152	metabolic process	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DLST
2 Novoseek chemical compound relationships for DLST gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
dihydrolipoamide	94.00	12	15075342 (2), 12652908 (1), 8619544 (1), 9450778 (1) (see all 10)
pyruvate	57.04	2	15075342 (2)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DLST)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DLST)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001933

Sigma-Aldrich siRNA for DLST

Sigma-Aldrich shRNA for DLST

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001933

REFSEQ mRNAs for DLST gene:

NM_001933.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001933

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001933
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001933
                                 untagged cDNA clone in CMV expression vector: NM_001933

Additional cDNA sequence:

AK289414.1 AK299505.1 AK300396.1 AK316463.1 BC000302.2 BC001922.1 BC002735.2 BX248276.1

BX248764.1 BX248774.1 CR456727.1 CR600036.1 D16373.1 D17297.1 L37418.1

18 DOTS entries:

DT.453765 DT.92439236 DT.75109878 DT.92439234 DT.100813975 DT.100813973 DT.91718816 DT.92014352

DT.99958124 DT.100761902 DT.100813977 DT.120771811 DT.75200367 DT.91924663 DT.92439235 DT.97790453

DT.97845678 DT.100813969

24/238 AceView cDNA sequences (see all 238 ):

AU133381 AI738526 AU133426 BM929953 AI768855 CK725012 AU131128 BX248764

AI805200 BF219729 CD724051 BM468606 BP341159 AI685838 BE671035 BU623022

BX248774 AI335698 AA291301 AW150246 BF056135 BX395796 BG057758 AL554351

highest scoring ESTs for DLST:

AW004933 AA088713 AA101666 AA101667 AA236650 AA262060 AA343667 AA443359 AA454025 AA683363

Unigene Cluster for DLST:

Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

Hs.525459 [show with all ESTs]

Unigene Representative Sequence: NM_001933

GeneLoc Exon Structure

3 Ensembl transcripts including schematic representations:

ENST00000238671 ENST00000334212 ENST00000334220

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DLST expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DLST

¹ / ² / ³

4 probe-sets matching DLST gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33258_g_at²^{, 3}	U95-A	2	1.00	0.53	0.97	0.92	D26535	0.20	0.50	0.38	1
45545_at²^{, 3}	U95-B	2	1.00	0.50	0.94	1.08	AW004933	1.00	0.90	0.95	1
215210_s_at²	U133-A	2	1.00	0.50	--	--	--	--	--	--	--
215210_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

GeneDecks DLST for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GCTTTGTATC

SOURCE GeneReport for Unigene cluster: Hs.525459
Expression variation in blood from EXPOLDB for DLST

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DLST gene from 5/28 species (see all 28 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DLST¹	--	dihydrolipoamide S-succinyltransferase (E2 component more	88.01(n) 89.59(a)	480388 XM_537510.2 XP_537510.2
chimpanzee (Pan troglodytes)	DLST¹	--	dihydrolipoamide S-succinyltransferase (E2 component more	99.48(n) 99.78(a)	453039 XM_510068.2 XP_510068.2
cow (Bos taurus)	DLST¹	--	dihydrolipoamide S-succinyltransferase (E2 component more	91.83(n) 94.04(a)	506888 NM_001075282.1 NP_001068750.1
rat (Rattus norvegicus)	Dlst¹	--	dihydrolipoamide S-succinyltransferase (E2 component more	88.15(n) 92.94(a)	299201 NM_001006981.1 NP_001006982.1
mouse (Mus musculus)	Dlst^{1, 5}	12⁵	dihydrolipoamide S-succinyltransferase (E2 component more^{1, 5}	89.31(n)¹ 92.7(a)¹	78920¹ NM_030225.3¹ NP_084501.1¹ AI849904⁵ AK005477⁵ (see all 53)

About this table Species with no ortholog for DLST

ENSEMBL Gene Tree for DLST

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/161 NCBI SNPs in DLST are shown (see all 161 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 71)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs10083386^1,2	A,C,F,H	74417338(+)	`TGGTTC/AATTCA`	1	--	ng5¹		4		EU EA WA	412
--	rs13391^1,2	A,C,F	74439876(+)	`TGAAAC/TGGATG`	1	--	ut3¹ ese³		2		MN	372
--	rs709887^1,2	A,C,F	74439132(+)	`ACCCCC/TGGGGA`	1	--	ut3¹ ese³		5		EA NA MN	396
--	rs8014499^1,2	A,C	74439886(+)	`GAGGTC/AATTTC`	1	--	ut3¹		1		MN	184
	rs11623342^1,2	C,F	74417690(+)	`TTCCAA/CAATGC`	1	--	ng5¹		4		NA EA	362
--	rs709888^1,2	A,C	74439099(+)	`TGCTTC/TTCCCT`	1	--	ut3¹ ese³		5		EA NA MN	336
--	rs3207445^1,2	F	74438863(+)	`GTCCCA/GGGTTA`	1	--	ut3¹ ese³		1		MN	184
	rs2070597^1,2	C	74439693(+)	`CTCTAA/GACTGA`	1	--	ut3¹ ese³		0	--	--	--	--
--	rs3759741^1,2	C	74416794(-)	`ggtagC/Tgaatg`	1	--	ng5¹		0	--	--	--	--
--	rs3207448^1,2	F	74438944(+)	`CAGGTC/TTTTTC`	1	--	ut3¹		1		MN	184

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HapMap Linkage Disequilibrium images for DLST (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 126063

2 Novoseek disease relationships for DLST gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
alzheimers disease	59.50	10	11825528 (2), 7974008 (1), 9894876 (1), 8584231 (1) (see all 8)
parkinson disease	12.50	3	9450778 (2), 10676873 (1)

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Genetic Association Database: DLST
Human Genome Epidemiology Navigator: DLST (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/40 PubMed articles for DLST gene (see all 40 ):

Isolation, characterization, and mapping of gene encoding dihydrolipoyl succinyltransferase (E2k) of human alpha-ketoglutarate dehydrogenase complex. (PubMed id 8009371)^{1, 2, 3} Ali G.... Blass J.P. (1994)
No association between DLST gene and Alzheimer's disease or Wernicke-Korsakoff syndrome. (PubMed id 11445257)^{1, 3, 6} Matsushita S....Higuchi S. (2001)
[Association between DLST gene polymorphism and Alzheimer's disease] (PubMed id 11825528)^{1, 3, 6} Ma Q....Yang J. (2001)
Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease. (PubMed id 11436125)^{1, 3, 6} Prince J.A....Brookes A.J. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Isolation, characterization and structural organization of the gene and pseudogene for the dihydrolipoamide succinyltransferase component of the human 2-oxoglutarate dehydrogenase complex. (PubMed id 8076640)^{3, 4} Nakano K....Matuda S. (1994)
Human dihydrolipoamide succinyltransferase: cDNA cloning and localization on chromosome 14q24.2-q24.3. (PubMed id 8268217)^{3, 4} Nakano K.... Miyata T. (1993)
Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population. (PubMed id 9894876)^{1, 3} Sheu K.F....Blass J.P. (1999)
Mutation analysis of the chromosome 14q24.3 dihydrolipoyl succinyltransferase (DLST) gene in patients with early-onset Alzheimer disease. (PubMed id 8584231)^{1, 3} Cruts M....Adolfsson R. (1995)
Substantial linkage disequilibrium across the dihydrolipoyl succinyltransferase gene region without Alzheimer's disease association. (PubMed id 15038610)^{1, 3} Brown A.M....Blass J.P. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 1743	HGNC: 2911	AceView: DLST	Ensembl:ENSG00000119689	euGenes: HUgn1743
ECgene: DLST	H-InvDB: DLST

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for DLST
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for DLST:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DLST-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DLST		Antibodies for DLST
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DLST		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (DLST)
	Antibodies (DLST)
	Chimera RNAi (DLST)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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Antibodies for DLST

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DLST Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for DLST

Summaries
for DLST

Genomic Location
for DLST

Proteins
for DLST

Protein Domains/
Families
for DLST

Gene Function
for DLST

Pathways & Interactions
for DLST

Drugs & Compounds
for DLST

Transcripts
for DLST

Expression
for DLST

Orthologs
for DLST

Paralogs
for DLST

SNPs/Variants
for DLST

Disorders & Mutations
for DLST

Medical News
for DLST

Publications
for DLST

Search for DLST

Genome Databases showing DLST

Other Databases showing DLST

Specialized Databases showing DLST

Licensable Technologies
for DLST

Services
for DLST

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DLST Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor DLST

Summariesfor DLST

Genomic Locationfor DLST

Proteinsfor DLST

Protein Domains/Familiesfor DLST

Gene Functionfor DLST

Pathways & Interactionsfor DLST

Drugs & Compoundsfor DLST

Transcriptsfor DLST

Expression for DLST

Orthologsfor DLST

Paralogsfor DLST

SNPs/Variantsfor DLST

Disorders & Mutationsfor DLST

Medical Newsfor DLST

Publicationsfor DLST

Search for DLST

Genome Databases showing DLST

Other Databases showing DLST

Specialized Databases showing DLST

Licensable Technologiesfor DLST

Servicesfor DLST

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DLST

Summaries
for DLST

Genomic Location
for DLST

Proteins
for DLST

Protein Domains/
Families
for DLST

Gene Function
for DLST

Pathways & Interactions
for DLST

Drugs & Compounds
for DLST

Transcripts
for DLST

Expression
for DLST

Orthologs
for DLST

Paralogs
for DLST

SNPs/Variants
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