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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DLGAP5 Gene

protein-coding   GIFtS: 51
GCID: GC14M055614

discs, large (Drosophila) homolog-associated protein 5

(Previous names: discs, large homolog 7 (Drosophila) )
(Previous symbol: DLG7)
 Explore 6 diseases affiliated with
DLGAP5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for DLGAP5    

Aliases
for DLGAP5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Discs, Large (Drosophila) Homolog-Associated Protein 51 2     Hepatoma Up-Regulated Protein2 3
DLG71 2 3     DAP-52 3
HURP1 2 3     DLG11
KIAA00081 3     Discs, Large Homolog 7 (Drosophila)1
Discs Large Homolog 72 3     Discs, Large Homolog 72
Disks Large-Associated Protein DLG72 3     Disks Large-Associated Protein 52

External Ids:    HGNC: 168641   Entrez Gene: 97872   Ensembl: ENSG000001267877   UniProtKB: Q153983   

Export aliases for DLGAP5 gene to outside databases

Previous GC identifers: GC14M054685 GC14M035777


Summaries
for DLGAP5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: DLGP5_HUMAN, Q15398
Function: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein
regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that
may be involved in CDH1-mediated adhesion and signaling in epithelial cells

Gene Wiki entry for DLGAP5


Genomic Views
for DLGAP5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DLGAP5 gene promoter:
         STAT5B   HOXA9B   HOXA9   AP-1   ATF-2   IRF-2   c-Jun   Meis-1a   CBF(2)   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DLGAP5 promoter sequence
   Search SABiosciences Chromatin IP Primers for DLGAP5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DLGAP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q22.3   Ensembl cytogenetic band:  14q22.3   HGNC cytogenetic band: 14q22.3

DLGAP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DLGAP5 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M055614:  view genomic region     (about GC identifiers)

Start:
 55,614,830 bp from pter      End:
 55,658,396 bp from pter
Size:
 43,567 bases      Orientation:
 minus strand

Proteins
for DLGAP5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DLGP5_HUMAN, Q15398 (See protein sequence)
Recommended Name: Disks large-associated protein 5  
Size: 846 amino acids; 95115 Da
Subunit: Interacts with CDK1. Interacts with the C-terminal proline-rich region of FBXO7. Recruited by FBXO7 to a SCF
(SKP1-CUL1-F-box) protein complex in a CDK1/Cyclin B-phosphorylation dependent manner. Interacts with CDH1
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic
cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells
Developmental stage: Elevated levels of expression detected in the G2/M phase of synchronized cultures of HeLa cells
Caution: It was localized to the spindle and the spindle pole (PubMed:12527899) but was later found to be localized to
the spindle and to be excluded from the spindle pole (PubMed:15561729)
Sequence caution: Sequence=BAA02797.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=CAD62583.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8MTM6 B4DRM8 Q86T11 Q8NG58
Alternative splicing: 3 isoforms:  Q15398-2   Q15398-1   Q15398-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DLGAP5: NX_Q15398

Post-translational modifications:

  • Ubiquitinated, leading to its degradation1
  • Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15398

    • DLGAP5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001139487.1  NP_055565.3  

    ENSEMBL proteins: 
     ENSP00000378815   ENSP00000247191   ENSP00000451747   ENSP00000452168  

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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DLGAP5

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm IEA--
    GO:0031616spindle pole centrosome ISS--


    DLGAP5 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for DLGAP5

    Protein Domains /
    Families
    for DLGAP5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DLGAP5 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR005026 GKAP

    Graphical View of Domain Structure for InterPro Entry Q15398

    ProtoNet protein and cluster: Q15398

    1 Blocks protein family: IPB005026 Guanylate-kinase-associated protein

    UniProtKB/Swiss-Prot: DLGP5_HUMAN, Q15398
    Similarity: Belongs to the SAPAP family


    Function
    for DLGAP5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DLGP5_HUMAN, Q15398
    Function: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein
    regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that
    may be involved in CDH1-mediated adhesion and signaling in epithelial cells

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004721phosphoprotein phosphatase activity ISS--
    GO:0005515protein binding IPI15987997


    DLGAP5 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Dlgap5tm1Tfts for DLGAP5
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Dlgap5):
     embryogenesis  reproductive system 

    DLGAP5 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for DLGAP5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Aurora A signaling
    		Aurora A signaling1.00


    1 BioSystems Pathway for DLGAP5 
        Aurora A signaling


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DLGAP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/11 Interacting proteins for DLGAP5 (Q153983 ENSP000002471914) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIM37O949723, ENSP000002622944I2D: score=4 STRING: ENSP00000262294
    BTRCQ9Y2973, ENSP000003592064I2D: score=2 STRING: ENSP00000359206
    FBXO7Q9Y3I13, ENSP000002660874I2D: score=1 STRING: ENSP00000266087
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    TRAF2Q129333, ENSP000002476684I2D: score=4 STRING: ENSP00000247668
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000087M phase of mitotic cell cycle ISS--
    GO:0007079mitotic chromosome movement towards spindle pole NAS12527899
    GO:0007267cell-cell signaling IEA--
    GO:0008283cell proliferation NAS12527899
    GO:0045842positive regulation of mitotic metaphase/anaphase transition NAS12527899


    DLGAP5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for DLGAP5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    DLGAP5 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DLGAP5
    1 Novoseek chemical compound relationship for DLGAP5 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    guanylate 42.7 2 15922738 (1), 11543626 (1)

    Search CenterWatch for drugs/clinical trials and news about DLGAP5 / DLGP5 

    Transcripts
    for DLGAP5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DLGAP5 gene (2 alternative transcripts): 
    NM_001146015.1  NM_014750.4  

    Unigene Cluster for DLGAP5:

    Discs, large (Drosophila) homolog-associated protein 5
    Hs.77695  [show with all ESTs]
    Unigene Representative Sequence: NM_001146015
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000395425 ENST00000247191(uc001xbt.3 uc001xbs.3) ENST00000554007
    ENST00000557645 ENST00000554067

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate DLGAP5:
    hsa-miR-623
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    Inhib. RNA
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DLGAP5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DLGAP5

    Additional cDNA sequence: 

    AB076695.1 AK291847.1 AK297480.1 AK299338.1 BC010658.1 BC016276.2 BT007344.1 BX248255.1 
    D13633.3 

    12 DOTS entries:

    DT.100713911  DT.100822950  DT.213788  DT.97843276  DT.120786886  DT.100822935  DT.100822949  DT.100659796 
    DT.120786417  DT.95163315  DT.92046233  DT.96085178 

    24/152 AceView cDNA sequences (see all 152):

    BM788630 CD644577 BE890401 BC016276 CA454937 AU124964 BX248255 CA488299 
    BX450059 BM831559 AI174844 BC010658 AI095895 AU124104 CR622849 BG574350 
    BM827600 BQ422141 AL708268 AU133356 BX103023 BM772338 BP365066 CB112147 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DLGAP5 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b ^
    SP1:                    -                                                                                                                                       
    SP2:                                                                                                                                                            
    SP3:                    -           -     -     -                                                                                                               
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 20 ^ 21a · 21b · 21c
    SP1:  -                     
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for DLGAP5

    Expression
    for DLGAP5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DLGAP5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCAGACACAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    DLGAP5 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 4 LifeMap Cells 
    NameCategory
    PureStem™ progenitor E44 (Embryonic Progenitor Cell)
    PureStem™ progenitor EN27 (Embryonic Progenitor Cell)
    PureStem™ progenitor F15 (Embryonic Progenitor Cell)
    Adult human kidney epithelial cells (Primary Cell)Kidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DLGAP5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DLGAP5

    SOURCE GeneReport for Unigene cluster: Hs.77695

    UniProtKB/Swiss-Prot: DLGP5_HUMAN, Q15398
    Tissue specificity: Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and
    placenta

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    In Situ
    Assay Products:     
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    Orthologs
    for DLGAP5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for DLGAP5 gene from 5/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves DLGAP51 discs, large (Drosophila) homolog-associated protein more 55.75(n)
    42.77(a)    		   423555  XM_421446.3  XP_421446.2 
    lizard
    (Anolis carolinensis)    		 Reptilia DLGAP56
    		 --
    		 33(a)
    		 1 ↔ 1
    		 GL343325.1(214945-231673)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BJ618790.12   -- 78.58(n)    BJ618790.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii dlgap51 discs, large (Drosophila) homolog-associated protein more 47.25(n)
    37.83(a)    		   447853  NM_001004592.1  NP_001004592.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta mars6
    		 mars
    		 9(a)
    		 1 ↔ 1
    		 2R(9390080-9393516)


    ENSEMBL Gene Tree for DLGAP5 (if available)
    TreeFam Gene Tree for DLGAP5 (if available) 

    Paralogs
    for DLGAP5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DLGAP5 gene
    DLGAP42  DLGAP12  DLGAP22  DLGAP32  

    DLGAP5 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for DLGAP5
    PGOHUM00000241890 PGOHUM00000233894


    Genomic Variants
    for DLGAP5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/948 NCBI SNPs in DLGAP5 are shown (see all 948)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs751420321,2
    		F,--55614362(+) GTCTTA/GTTATG 2 -- ds50011Minor allele frequency- G:0.18WA 118
    rs1406732401,2
    		--55614399(+) ATTGTC/TGTGTT 2 -- ds50010--------
    rs587097721,2
    		C,--55614511(+) AAAAAG/CCATTT 2 -- ds50011Minor allele frequency- C:0.50WA 2
    rs1414609941,2
    		C,--55614546(+) ATGGG-/AAAATA 2 -- ds50010--------
    rs22742731,2
    		C,F,A,H,--55614636(-) CTTTTC/TGGATT 2 -- ds500121Minor allele frequency- T:0.33NS EA NA WA CSA 2345
    rs22742721,2
    		C,F,H,--55614794(-) CACTTT/CAAACA 2 -- ds50018Minor allele frequency- C:0.15NS EA WA CSA 658
    rs1838566171,2
    		--55614854(+) AAGGCA/GCAGTA 2 -- ut310--------
    rs1397989861,2
    		C,--55615001(+) CAAAA-/TTTCAA 2 -- ut310--------
    rs2005989721,2
    		F--55615054(+) GTTTGG/AATTTA 2 -- ut311Minor allele frequency- A:0.00EU 1073
    rs1884821461,2
    		C,--55615105(+) GTAATC/TAGGTT 3 L ut31 syn10--------

    HapMap Linkage Disequilibrium report for DLGAP5 (55614830 - 55658396 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DLGAP5: --

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    Disorders / Diseases
    for DLGAP5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DLGAP5 for disorders           About GeneDecksing

    6 diseases for DLGAP5:    About MalaCards
    pleomorphic liposarcoma    adrenocortical tumor    hepatocellular carcinoma    liposarcoma
    liver cancer    carcinoma

    3 Novoseek disease relationships for DLGAP5 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hepatocellular carcinoma 46 6 19486529 (1), 15922738 (1), 12527899 (1), 16364248 (1)
    tumors 0 5 14871824 (2), 17322106 (1), 11543626 (1), 16364248 (1)
    cancer 0 1 12527899 (1)


    Export disorders for DLGAP5 gene to outside databases

    Publications
    for DLGAP5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DLGAP5 gene, integrated from 9 sources (see all 47):
    (articles sorted by number of sources associating them with DLGAP5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2, 3 Nomura N.... Tabata S. (1994)
    2. Fbx7 functions in the SCF complex regulating Cdk1-cyclin B- phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region. (PubMed id 15145941)1, 2, 9 Hsu J.-M.... Huang C.-Y.F. (2004)
    3. Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma. (PubMed id 12527899)1, 2, 9 Tsou A.-P.... Chou C.-K. (2003)
    4. Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A. (PubMed id 15987997)1, 2, 9 Yu C.T....Huang C.Y. (2005)
    5. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Prediction of the coding sequences of unidentified hu man genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell li ne KG-1 (supplement). (PubMed id 7584028)1, 3 Nomura N....Tabata S. (1994)
    8. HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture. (PubMed id 16769820)1, 9 Wong J. and Fang G. (2006)
    9. Characterization of a novel human cell-cycle-regulated homologue of Drosophila dlg1. (PubMed id 11543626)1, 9 Bassal S....van der Spek P.J. (2001)
    10. Gene expression analysis of hematopoietic progenitor cells identifies Dlg7 as a potential stem cell gene. (PubMed id 17322106)1, 9 Gudmundsson K.O....Rafnar T. (2007)

    External Searches for DLGAP5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing DLGAP5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9787 HGNC: 16864 AceView: DLG7 Ensembl:ENSG00000126787 euGenes: HUgn9787
    ECgene: DLGAP5 H-InvDB: DLGAP5

    Other Databases showing DLGAP5 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0008

    Specialized Databases showing DLGAP5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DLGAP5 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for DLGAP5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for DLGAP5 gene:
    Search GeneIP for patents involving DLGAP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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