Aliases for DLGAP4 Gene
External Ids for DLGAP4 Gene
Previous GeneCards Identifiers for DLGAP4 Gene
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for DLGAP4 Gene
DLGAP4 (Discs Large Homolog Associated Protein 4) is a Protein Coding gene. An important paralog of this gene is DLGAP3.
UniProtKB/Swiss-Prot for DLGAP4 Gene
May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.