DLG5 Gene
protein-coding GIFtS: 57
GCID: GC10M079550
|
|
discs, large homolog 5 (Drosophila)(Previous names: discs, large (Drosophila) homolog 5 )
| |
Aliases
for DLG5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Discs, Large Homolog 5 (Drosophila)1 2 | | Discs, Large (Drosophila) Homolog 51 | | KIAA05831 3 5 | | LP-DLG2 | | PDLG2 3 5 | | P-DLG52 | | Discs Large Protein P-Dlg2 3 | | Discs Large Protein LP-DLG2 | | Placenta And Prostate DLG2 3 | | Disks Large Homolog 52 | | P-Dlg1 | | Large Type Of P-DLG2 |
Export aliases for DLG5 gene to outside databasesPrevious GC identifers: GC10M078507 GC10M078760 GC10M079442 GC10M078895 GC10M079220 GC10M073546 |
Summaries
for DLG5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DLG5:
This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylatekinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, inaddition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact.The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components ofadherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals tothe cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been describedbut their biological nature has not been determined. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: DLG5_HUMAN, Q8TDM6Function: May play a role at the plasma membrane in the maintenance of the structure of epithelial cells and in thetransmission of extracellular signals to the membrane and cytoskeleton
Gene Wiki entry for DLG5
|
Genomic Views
for DLG5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DLG5 gene promoter:
Tal-1 Meis-1b Egr-4 E47 NF-AT4 Sox9 Meis-1a Hlf Ik-1 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for DLG5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DLG5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q23 Ensembl cytogenetic band: 10q22.3 HGNC cytogenetic band: 10q23DLG5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M079550: view genomic region
(about GC identifiers)
Start:
|
79,550,549 bp from pter |
End:
|
79,686,378 bp from pter |
Size:
|
135,830 bases |
Orientation:
|
minus strand |
|
Proteins
for DLG5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DLG5_HUMAN, Q8TDM6 (See
protein sequence)Recommended Name: Disks large homolog 5 Size: 1919 amino acids; 213868 Da
Subunit: Interacts with MPP1. Interacts with CTNNB1 and with the third SH3 domain of SORBS3 to form a ternary complex
Subcellular location: Cell junction. Cell membrane; Peripheral membrane protein. Note=Localized at sites of cell-cellcontact
Sequence caution: Sequence=AAI17696.1; Type=Erroneous initiation; Sequence=BAA25509.2; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for DLG5:1UIT (3D)
Secondary accessions: A6H8Y3 Q149N1 Q5T1H7 Q5T1H8 Q6DKG3 Q86WC0 Q8TDM7 Q9UE73 Q9Y4E3Alternative splicing: 5 isoforms: Q8TDM6-1 Q8TDM6-2 Q8TDM6-3 Q8TDM6-4 Q8TDM6-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DLG5: NX_Q8TDM6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TDM6
DLG5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004738.3
ENSEMBL proteins: ENSP00000361467 ENSP00000394797 ENSP00000361464
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
DLG5 for ontologies About GeneDecksing
DLG5 Antibody Products:
Assay Products for DLG5: |
Protein
Domains /
Families
for DLG5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DLG5 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q8TDM6ProtoNet protein and cluster: Q8TDM6 3 Blocks protein families: IPB001478 PDZ/DHR/GLGF domain IPB008144 Guanylate kinase IPB011511 Variant SH3
UniProtKB/Swiss-Prot: DLG5_HUMAN, Q8TDM6Similarity: Belongs to the MAGUK familySimilarity: Contains 1 guanylate kinase-like domainSimilarity: Contains 4 PDZ (DHR) domainsSimilarity: Contains 1 SH3 domain |
Function
for DLG5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DLG5_HUMAN, Q8TDM6Function: May play a role at the plasma membrane in the maintenance of the structure of epithelial cells and in thetransmission of extracellular signals to the membrane and cytoskeleton Genatlas biochemistry entry for DLG5:Drosophila tumor suppressor gene,discs large 5,giant larvae homolog,expressed in placenta and in epithelial glands(prostate),interacting with p55 palmitoylated membrane protein and putatively involved in the maintenance of thestructure of epithelial cell
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DLG5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DLG5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DLG5 (NM_004747) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DLG5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DLG5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DLG5 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
DLG5 for ontologies About GeneDecksing
Animal Models:
7 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Dlg5):
DLG5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DLG5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DLG5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/23 Interacting proteins for DLG5 (Q8TDM62, 3 ENSP000003614674) via UniProtKB, MINT, STRING, and/or I2D (see all 23)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
DLG5 for ontologies About GeneDecksing
|
Drugs & Compounds
for DLG5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DLG5
Search CenterWatch for drugs/clinical trials and news about DLG5
|
Transcripts
for DLG5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DLG5 gene: NM_004747.3 Unigene Cluster for DLG5: Discs, large homolog 5 (Drosophila) Hs.652690 [show with all ESTs]Unigene Representative Sequence: BC14679411 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372391(uc001jzj.3 uc001jzk.3 uc009xru.1) ENST00000424842(uc001jzi.3)
ENST00000463362 ENST00000475613 ENST00000459739 ENST00000489547 ENST00000484525
ENST00000476354 ENST00000468332(uc001jzl.4) ENST00000466198 ENST00000372388
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DLG5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DLG5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DLG5 (NM_004747) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DLG5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DLG5 |
Additional cDNA sequence: AB011155.2 AB091676.1 AK055172.1 AK314771.1 BC015053.2 BC030250.1 BC073996.1 BC086867.1 BC117695.2 BC146794.1 BX649131.1 U61843.1 24 DOTS entries: DT.451967 DT.97759907 DT.97818646 DT.101959733 DT.100041958 DT.86846729 DT.100796572 DT.40116370 DT.91749142 DT.95198395 DT.91932817 DT.75148599 DT.92030642 DT.121279186 DT.121279241 DT.435304 DT.92442232 DT.92442234 DT.95108045 DT.95220815 DT.100741522 DT.86856689 DT.91828285 DT.97767563 24/345 AceView cDNA sequences (see all 345): BU685134 AA056020 AI039275 BF437478 BU687526 AI569668 BQ670004 BC013378 AA418370 AI694414 AW069626 AI421067 T33039 BF368609 AL712968 AI391482 AI804171 BC030250 AK055172 AI951390 BU190189 AI687594 AK055265 AL536173
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for DLG5 (see all 13) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | · | 17c | ^ |
|---|
|
| SP1: | | | - | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | - | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18a | · | 18b | ^ | 19a | · | 19b | · | 19c | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27a | · | 27b | · | 27c | ^ | 28a | · | 28b | ^ | 29a | · | 29b | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33a | · | 33b | ^ | 34a | · | 34b | · |
|---|
|
| SP1: | - | | | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | |
| SP2: | - | | | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | - | | | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | |
| SP4: | - | | | | - | | - | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for DLG5
|
Expression
for DLG5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DLG5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See DLG5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DLG5
SOURCE GeneReport for Unigene cluster: Hs.652690
UniProtKB/Swiss-Prot: DLG5_HUMAN, Q8TDM6Tissue specificity: Highly expressed in the placenta and prostate. Expressed at a lower level in the thyroid, spinalcord, trachea, adrenal gland, skeletal muscle, pancreas, heart, brain, liver and kidney. A short splice product showsmore limited expression, being absent from at least the brain
SABiosciences Expression via Pathway-Focused PCR Array including DLG5:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DLG5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DLG5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DLG5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DLG5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DLG5 |
Orthologs
for DLG5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for DLG5 gene from 6/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
DLG51 |
discs, large homolog 5 (Drosophila) |
69.02(n)
72.57(a) |
|
423728 XM_421604.2 XP_421604.2 |
lizard
(Anolis carolinensis) |
Reptilia |
DLG56 |
-- |
62(a) |
1 ↔ 1 |
GL343196.1(5176328-5264302) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.128212 |
Xenopus laevis transcribed sequence with weak similarity more |
74.95(n) |
|
BJ073452.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
dlg5a1 |
discs, large homolog 5a (Drosophila) |
63.07(n)
58.38(a) |
|
569065 NM_001145603.1 NP_001139075.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG65093 |
-- |
38(a) |
|
32F2 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
magu-41 |
Protein MAGU-4 |
41.32(n)
30.36(a) |
|
177860 NM_069404.2 NP_501805.1 |
ENSEMBL Gene Tree for DLG5 (if available)
TreeFam Gene Tree for DLG5 (if available) |
Paralogs
for DLG5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DLG5 gene
- TJP22 TJP32 TJP12
2 SIMAP similar genes for DLG5 using alignment to 2 protein entries: DLG5_HUMAN (see all proteins):DKFZp761P0818 DLG4
DLG5 for paralogs About GeneDecksing
|
Genomic Variants
for DLG5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DLG5 (79550549 - 79686378 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for DLG5
6 CNVs: 47890 2880 3813 48035 8662 71049
Human Gene Mutation Database (HGMD): DLG5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DLG5 |
|
Disorders
/ Diseases
for DLG5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DLG5 for disorders About GeneDecksing
OMIM gene information: 604090
OMIM disorders: --
20/23  diseases for DLG5 (see all 23): About MalaCardssclerosing cholangitis primary sclerosing cholangitis primary biliary cirrhosis prostatitis
cholangitis papilledema inflammatory bowel disease dilated cardiomyopathy
ulcerative colitis rheumatoid arthritis crohn's disease cardiomyopathy
alzheimer's disease arthritis meningioma pancreatic cancer
colorectal cancer breast cancer pancreatitis thyroiditis
2 diseases from the University of Copenhagen DISEASES database for DLG5:Crohn's disease Ulcerative colitis Genetic Association Database (GAD): DLG5
Human Genome Epidemiology (HuGE) Navigator: DLG5 (40 documents)
Export disorders for DLG5 gene to outside databases
|
Publications
for DLG5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DLG5 gene, integrated from 9 sources (see all 70):
(articles sorted by number of sources associating them with DLG5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55. (PubMed id 9738934)1, 2, 3, 9 Nakamura H.... Saya H. (1998)
- Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD. (PubMed id 16344053)1, 4, 9 Vermeire S....Rutgeerts P. (2005)
- Association of DLG5 R30Q variant with inflammatory bowel disease. (PubMed id 15841097)1, 4 Daly M.J....Rioux J.D. (2005)
- DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population. (PubMed id 15843420)1, 4 Noble C.L....Satsangi J. (2005)
- Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. (PubMed id 15955786)1, 4 Torok H.P....Folwaczny C. (2005)
- Genetic variation in DLG5 is associated with inflammatory bowel disease. (PubMed id 15107852)1, 4 Stoll M....Schreiber S. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell- cell contact. (PubMed id 12657639)1, 2 Wakabayashi M....Kioka N. (2003)
- The cloning, genomic organization and tissue expression profile of the human DLG5 gene. (PubMed id 11876824)1, 2 Shah G.... Roberts R. (2002)
|
External Searches for DLG5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DLG5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DLG5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing DLG5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for DLG5 gene:
Search GeneIP for patents involving DLG5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for DLG5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DLG5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DLG5 | | | OriGene Protein Over-expression Lysate for DLG5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DLG5 | | OriGene 3'-UTR Clone for DLG5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DLG5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DLG5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DLG5 | | OriGene Custom Protein Services for DLG5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DLG5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DLG5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DLG5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DLG5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DLG5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DLG5 |
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| | | | Search Tocris compounds for DLG5 |
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 | | | DLG5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DLG5 |
|  |  |  | | | | Search ThermoFisher Antibodies for DLG5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DLG5 |
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