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Aliases for DLEU7 Gene

Aliases for DLEU7 Gene

  • Deleted In Lymphocytic Leukemia, 7 2 3
  • Deleted In Lymphocytic Leukemia 7 4
  • LEU7 4

External Ids for DLEU7 Gene

Summaries for DLEU7 Gene

GeneCards Summary for DLEU7 Gene

DLEU7 (Deleted In Lymphocytic Leukemia, 7) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DLEU7 Gene

Genomics for DLEU7 Gene

Genomic Location for DLEU7 Gene

Start:
50,711,008 bp from pter
End:
50,843,939 bp from pter
Size:
132,932 bases
Orientation:
Minus strand

Genomic View for DLEU7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DLEU7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DLEU7 Gene

Proteins for DLEU7 Gene

  • Protein details for DLEU7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UYE1-LEU7_HUMAN
    Recommended name:
    Leukemia-associated protein 7
    Protein Accession:
    Q6UYE1
    Secondary Accessions:
    • Q2M2E4
    • Q6ZT82

    Protein attributes for DLEU7 Gene

    Size:
    221 amino acids
    Molecular mass:
    23924 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DLEU7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DLEU7 Gene

Proteomics data for DLEU7 Gene at MOPED

Post-translational modifications for DLEU7 Gene

No Post-translational modifications

Other Protein References for DLEU7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DLEU7 Gene

Domains for DLEU7 Gene

Protein Domains for DLEU7 Gene

ProtoNet:
genes like me logo Genes that share domains with DLEU7: view

No data available for Gene Families and UniProtKB/Swiss-Prot for DLEU7 Gene

Function for DLEU7 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DLEU7 Gene

Localization for DLEU7 Gene

No data available for Gene Ontology (GO) - Cellular Components for DLEU7 Gene

Pathways for DLEU7 Gene

SuperPathways for DLEU7 Gene

No Data Available

Interacting Proteins for DLEU7 Gene

Gene Ontology (GO) - Biological Process for DLEU7 Gene

None

No data available for Pathways by source for DLEU7 Gene

Transcripts for DLEU7 Gene

mRNA/cDNA for DLEU7 Gene

(5) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DLEU7 Gene

Deleted in lymphocytic leukemia, 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DLEU7 Gene

No ASD Table

Relevant External Links for DLEU7 Gene

GeneLoc Exon Structure for
DLEU7
ECgene alternative splicing isoforms for
DLEU7

Expression for DLEU7 Gene

mRNA expression in normal human tissues for DLEU7 Gene

mRNA differential expression in normal tissues according to GTEx for DLEU7 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (4.8), Brain - Anterior cingulate cortex (BA24) (4.8), and Brain - Cortex (4.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for DLEU7 Gene

SOURCE GeneReport for Unigene cluster for DLEU7 Gene Hs.710878

mRNA Expression by UniProt/SwissProt for DLEU7 Gene

Q6UYE1-LEU7_HUMAN
Tissue specificity: Ubiquitous.
genes like me logo Genes that share expressions with DLEU7: view

Orthologs for DLEU7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for DLEU7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DLEU7 36
  • 100 (n)
  • 100 (a)
DLEU7 37
  • 71 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DLEU7 36
  • 81.86 (n)
  • 71.23 (a)
mouse
(Mus musculus)
Mammalia Dleu7 36
  • 83.33 (n)
  • 83.82 (a)
Dleu7 16
Dleu7 37
  • 58 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DLEU7 37
  • 36 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dleu7 36
  • 83.58 (n)
  • 85.29 (a)
chicken
(Gallus gallus)
Aves DLEU7 36
  • 50.8 (n)
  • 39.31 (a)
DLEU7 37
  • 27 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii DLEU7 37
  • 17 (a)
OneToOne
Species with no ortholog for DLEU7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DLEU7 Gene

ENSEMBL:
Gene Tree for DLEU7 (if available)
TreeFam:
Gene Tree for DLEU7 (if available)

Paralogs for DLEU7 Gene

No data available for Paralogs for DLEU7 Gene

Variants for DLEU7 Gene

Sequence variations from dbSNP and Humsavar for DLEU7 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs111932 -- 50,760,002(-) TGGAA(C/G)CAGGT intron-variant
rs111933 -- 50,759,929(-) GAAGG(A/G)AGGGT intron-variant
rs487601 -- 50,758,660(-) CCTCT(G/T)TCCAA intron-variant
rs495568 -- 50,754,959(-) tccag(C/T)gaaga intron-variant
rs499211 -- 50,754,590(-) gctgc(C/T)ttcag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DLEU7 Gene

Variant ID Type Subtype PubMed ID
esv273333 CNV Insertion 20981092
nsv437786 CNV Loss 16327808
esv2593545 CNV Deletion 19546169

Relevant External Links for DLEU7 Gene

HapMap Linkage Disequilibrium report
DLEU7
Human Gene Mutation Database (HGMD)
DLEU7

Disorders for DLEU7 Gene

Relevant External Links for DLEU7

Genetic Association Database (GAD)
DLEU7
Human Genome Epidemiology (HuGE) Navigator
DLEU7
genes like me logo Genes that share disorders with DLEU7: view

No data available for UniProtKB/Swiss-Prot for DLEU7 Gene

Publications for DLEU7 Gene

  1. Characterization of a novel B-CLL candidate gene -- DLEU7 -- located in the 13q14 tumor suppressor locus. (PMID: 14706829) Hammarsund M. … Grander D. (FEBS Lett. 2004) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Many sequence variants affecting diversity of adult human height. (PMID: 18391951) Gudbjartsson D.F. … Stefansson K. (Nat. Genet. 2008) 3 49
  4. Genome-wide association analysis identifies 20 loci that influence adult height. (PMID: 18391952) Weedon M.N. … Frayling T.M. (Nat. Genet. 2008) 3 49
  5. Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966. (PMID: 19266077) Sovio U. … Jarvelin M.R. (PLoS Genet. 2009) 3 49

Products for DLEU7 Gene

Sources for DLEU7 Gene

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