DLEU2L Gene
protein-coding GIFtS: 26
GCID: GC01P064014
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deleted in lymphocytic leukemia 2-like(Previous name: BCMS upstream neighbor-like )
(Previous symbol: BCMSUNL)
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Aliases
for DLEU2L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| Deleted In Lymphocytic Leukemia 2-Like1 2 | | BCMSUNL1 2 | | BCMS Upstream Neighbor-Like1 |
| External Ids: | HGNC: 132251 | Entrez Gene: 794692 | Ensembl: ENSG000001166527 | UniProtKB: Q5JX124 | | ORGUL members: | |
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| NONCODE:n342265 | |
Export aliases for DLEU2L gene to outside databasesPrevious GC identifers: GC01P063787 GC01P062122
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Summaries
for DLEU2L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for DLEU2L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DLEU2L gene promoter:
AML1a ATF-2 Bach2 POU6F1 (c2) AREB6 PPAR-gamma1 FOXJ2 (long isoform) PPAR-gamma2 FOXJ2 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for DLEU2L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DLEU2L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p31-p22 Ensembl cytogenetic band: 1p31.3 HGNC cytogenetic band: 1p31-p22DLEU2L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P064014: view genomic region
(about GC identifiers)
Start:
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64,014,635 bp from pter |
End:
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64,016,307 bp from pter |
Size:
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1,673 bases |
Orientation:
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plus strand |
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Proteins
for DLEU2L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/TrEMBL: Q5JX12 (See
protein sequence)Recommended Name: Protein DLEU2L Size: 55 amino acids; 6661 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataDLEU2L Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000360127 ENSP00000340138
Human Recombinant Protein Products:
DLEU2L Antibody Products:
Assay Products for DLEU2L: |
Protein
Domains /
Families
for DLEU2L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5JX12 |
Function
for DLEU2L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DLEU2L |
|
Pathways & Interactions
for DLEU2L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DLEU2L
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Drugs & Compounds
for DLEU2L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DLEU2L
Search CenterWatch for drugs/clinical trials and news about DLEU2L 
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Transcripts
for DLEU2L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for DLEU2L: Deleted in lymphocytic leukemia 2-like Hs.659291 [show with all ESTs]Unigene Representative Sequence: AK0224192 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000371086 ENST00000340052
Additional cDNA sequence: AF254117.1 AK022419.1 NR_002771.1 4 DOTS entries: DT.95368068 DT.211811 DT.92427427 DT.95368067
GeneLoc Exon Structure
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Expression
for DLEU2L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DLEU2L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See DLEU2L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DLEU2L
SOURCE GeneReport for Unigene cluster: Hs.659291
SABiosciences Custom PCR Arrays for DLEU2L
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat DLEU2L | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DLEU2L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DLEU2L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DLEU2L |
Orthologs
for DLEU2L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for DLEU2L (if available)
TreeFam Gene Tree for DLEU2L (if available) |
Paralogs
for DLEU2L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DLEU2L gene
DLEU2L for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for DLEU2L
PGOHUM00000248398
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Genomic Variants
for DLEU2L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for DLEU2L (64014635 - 64016307 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DLEU2L: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DLEU2L |
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Disorders
/ Diseases
for DLEU2L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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DLEU2L for disorders About GeneDecksing
4  diseases for DLEU2L: About MalaCardslymphocytic leukemia leukemia mantle cell lymphoma chronic lymphocytic leukemia
1 disease from the University of Copenhagen DISEASES database for DLEU2L:Chronic lymphocytic leukemia Export disorders for DLEU2L gene to outside databases
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Publications
for DLEU2L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed article for DLEU2L gene integrated from 9 sources:
(articles sorted by number of sources associating them with DLEU2L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31, BCMSUN-like. (PubMed id 11072235)1, 3 Mertens D....Lichter P. (2000)
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External Searches for DLEU2L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing DLEU2L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing DLEU2L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DLEU2L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DLEU2L | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for DLEU2L gene:
Search GeneIP for patents involving DLEU2L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DLEU2L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DLEU2L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DLEU2L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DLEU2L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DLEU2L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DLEU2L | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DLEU2L |
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 |  |  |  | |
| | | | Search Tocris compounds for DLEU2L |
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 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DLEU2L |
|  |  |  | | | | Search ThermoFisher Antibodies for DLEU2L |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DLEU2L |
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