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Aliases for DLEU2L Gene

Aliases for DLEU2L Gene

  • Deleted In Lymphocytic Leukemia 2-Like 2 3 5
  • BCMS Upstream Neighbor-Like 2 3
  • BCMSUNL 3

External Ids for DLEU2L Gene

Previous HGNC Symbols for DLEU2L Gene

  • BCMSUNL

Previous GeneCards Identifiers for DLEU2L Gene

  • GC01P063787
  • GC01P064014
  • GC01P062122

Summaries for DLEU2L Gene

GeneCards Summary for DLEU2L Gene

DLEU2L (Deleted In Lymphocytic Leukemia 2-Like) is a Pseudogene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DLEU2L Gene

Genomics for DLEU2L Gene

Regulatory Elements for DLEU2L Gene

Enhancers for DLEU2L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G063932 0.9 dbSUPER 24.6 +385.5 385534 1.1 ZFP64 ZNF366 ZNF354C ZNF680 ZNF654 ZBTB11 ZNF426 REST ZNF623 ZNF781 EFCAB7 ROR1 DLEU2L GC01M063941 GC01M063862
GH01G063522 1.2 ENCODE 12.7 -23.6 -23626 2.8 CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 ITGB3BP EFCAB7 DLEU2L FOXD3-AS1 FOXD3 ROR1 ALG6 LOC441887 RN7SL488P
GH01G064522 0.9 dbSUPER 14.1 +978.7 978689 6.0 ZFP64 ZNF366 SCRT2 FOS ZNF680 ZNF654 ZBTB11 ZNF426 OVOL3 REST CACHD1 DLEU2L LINC01359 SLC2A3P2 ROR1 GC01P064556
GH01G064345 0.9 ENCODE 9.9 +798.6 798611 0.2 ZSCAN4 INSM2 ZEB1 ZNF155 ZNF366 ZNF416 FOS ZNF391 ZIK1 ZNF398 EFCAB7 SLC2A3P2 LINC01359 ROR1 JAK1 DLEU2L GC01P064331 LOC105378774
GH01G063951 0.8 FANTOM5 dbSUPER 9.9 +404.6 404583 0.2 ZFHX2 ZNF621 EGR2 DLEU2L ROR1 GC01M063949 GC01M064030 RNU6-809P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DLEU2L on UCSC Golden Path with GeneCards custom track

Genomic Location for DLEU2L Gene

Chromosome:
1
Start:
63,547,082 bp from pter
End:
63,550,636 bp from pter
Size:
3,555 bases
Orientation:
Plus strand

Genomic View for DLEU2L Gene

Genes around DLEU2L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DLEU2L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DLEU2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DLEU2L Gene

Proteins for DLEU2L Gene

Post-translational modifications for DLEU2L Gene

No Post-translational modifications

No data available for DME Specific Peptides for DLEU2L Gene

Domains & Families for DLEU2L Gene

Suggested Antigen Peptide Sequences for DLEU2L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains and UniProtKB/Swiss-Prot for DLEU2L Gene

Function for DLEU2L Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DLEU2L Gene

Localization for DLEU2L Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DLEU2L gene
Compartment Confidence
extracellular 2
mitochondrion 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for DLEU2L Gene

Pathways & Interactions for DLEU2L Gene

SuperPathways for DLEU2L Gene

No Data Available

Interacting Proteins for DLEU2L Gene

Gene Ontology (GO) - Biological Process for DLEU2L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DLEU2L Gene

Drugs & Compounds for DLEU2L Gene

No Compound Related Data Available

Transcripts for DLEU2L Gene

mRNA/cDNA for DLEU2L Gene

(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DLEU2L Gene

Deleted in lymphocytic leukemia 2-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DLEU2L Gene

No ASD Table

Relevant External Links for DLEU2L Gene

GeneLoc Exon Structure for
DLEU2L
ECgene alternative splicing isoforms for
DLEU2L

Expression for DLEU2L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DLEU2L Gene

mRNA differential expression in normal tissues according to GTEx for DLEU2L Gene

This gene is overexpressed in Muscle - Skeletal (x9.5).

NURSA nuclear receptor signaling pathways regulating expression of DLEU2L Gene:

DLEU2L

SOURCE GeneReport for Unigene cluster for DLEU2L Gene:

Hs.659291

Evidence on tissue expression from TISSUES for DLEU2L Gene

  • Nervous system(2.4)
genes like me logo Genes that share expression patterns with DLEU2L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DLEU2L Gene

Orthologs for DLEU2L Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for DLEU2L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DLEU2L 35
  • 98 (a)
OneToOne
Species where no ortholog for DLEU2L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for DLEU2L Gene

ENSEMBL:
Gene Tree for DLEU2L (if available)
TreeFam:
Gene Tree for DLEU2L (if available)

Paralogs for DLEU2L Gene

No data available for Paralogs for DLEU2L Gene

Variants for DLEU2L Gene

Sequence variations from dbSNP and Humsavar for DLEU2L Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1002439658 -- 63,550,716(+) ATTCT(A/G)GAAGA intron-variant, downstream-variant-500B
rs1003709773 -- 63,549,387(+) TTTAG(C/T)TGATG intron-variant, nc-transcript-variant
rs1004395004 -- 63,547,043(+) ATTCC(C/T)ACCTC intron-variant, upstream-variant-2KB
rs1004982530 -- 63,547,533(+) GTGTC(A/G)TATGA intron-variant, upstream-variant-2KB
rs1007029182 -- 63,549,811(+) TGTGA(A/G)AGATG intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for DLEU2L Gene

Variant ID Type Subtype PubMed ID
nsv1001451 CNV loss 25217958
nsv546434 CNV loss 21841781

Variation tolerance for DLEU2L Gene

Gene Damage Index Score: 0.01; 0.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for DLEU2L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DLEU2L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DLEU2L Gene

Disorders for DLEU2L Gene

Relevant External Links for DLEU2L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DLEU2L

No disorders were found for DLEU2L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DLEU2L Gene

Publications for DLEU2L Gene

  1. BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31, BCMSUN-like. (PMID: 11072235) Mertens D. … Lichter P. (Int. J. Cancer 2000) 2 3 64

Products for DLEU2L Gene

Sources for DLEU2L Gene

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