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Aliases for DLEU2 Gene

Subcategory (RNA class) for DLEU2 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for DLEU2 Gene

  • Deleted In Lymphocytic Leukemia 2 (Non-Protein Coding) 2 3 5
  • Mir-15a-16-1 Cluster Host Gene (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 22 2 3
  • Ret Finger Protein 2 Opposite Strand 2 3
  • Deleted In Lymphocytic Leukemia, 2 2 3
  • Leukemia Associated Gene 2 3
  • Non-Protein Coding RNA 22 2
  • NCRNA00022 3
  • LINC00022 3
  • MIR15AHG 3
  • TRIM13OS 3
  • BCMSUN 3
  • RFP2OS 3
  • Leu2 3
  • DLB2 3
  • 1B4 3

External Ids for DLEU2 Gene

Previous HGNC Symbols for DLEU2 Gene

  • DLB2
  • BCMSUN
  • RFP2OS

Previous GeneCards Identifiers for DLEU2 Gene

  • GC13M048617
  • GC13M044605
  • GC13M049554
  • GC13M048415
  • GC13M049515
  • GC13M050558
  • GC13M031351

Summaries for DLEU2 Gene

GeneCards Summary for DLEU2 Gene

DLEU2 (Deleted In Lymphocytic Leukemia 2 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Gene Wiki entry for DLEU2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DLEU2 Gene

Genomics for DLEU2 Gene

Regulatory Elements for DLEU2 Gene

Enhancers for DLEU2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13G050096 0.9 dbSUPER 16.9 +26.5 26468 6.5 ELF3 PKNOX1 FOXA2 CBX3 RAD21 RARA GATA2 CBX5 FOS CREM DLEU2 KCNRG EBPL CTAGE10P RPL18P10 GC13P050084
GH13G050121 2 FANTOM5 Ensembl ENCODE dbSUPER 5.7 -1.0 -1037 10.1 CREB3L1 AGO1 FEZF1 DMAP1 ZNF143 ZNF263 SP3 NFYC TBX21 MEF2D DLEU1 RNASEH2B-AS1 CTAGE10P RNASEH2B KCNRG TRIM13 EBPL DLEU2 ARL11 ENSG00000274270
GH13G050116 1 Ensembl ENCODE dbSUPER 0.4 +9.2 9213 0.6 GATA3 PRDM6 JUND DLEU1 RNASEH2B-AS1 RNASEH2B KCNRG DLEU2 ENSG00000273541
GH13G050105 1 Ensembl ENCODE dbSUPER 0.4 +18.9 18859 2.1 PRDM6 ZFP64 MYNN JUNB FOXP2 DLEU1 KCNRG DLEU7-AS1 DLEU7 PHF11 ENSG00000273541 DLEU2
GH13G050117 0.9 Ensembl dbSUPER 0.4 +8.5 8520 0.4 MAFG OVOL3 FEZF1 PRDM6 ZNF316 ZNF341 EMSY MAFK PRDM4 NR2C2 DLEU1 RNASEH2B RNASEH2B-AS1 KCNRG DLEU2 ENSG00000273541
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DLEU2 on UCSC Golden Path with GeneCards custom track

Promoters for DLEU2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000062809 720 3201 PKNOX1 FOXA2 CREB3L1 AGO1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B

Genomic Location for DLEU2 Gene

Chromosome:
13
Start:
49,982,552 bp from pter
End:
50,125,720 bp from pter
Size:
143,169 bases
Orientation:
Minus strand

Genomic View for DLEU2 Gene

Genes around DLEU2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DLEU2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DLEU2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DLEU2 Gene

Proteins for DLEU2 Gene

Post-translational modifications for DLEU2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DLEU2 Gene

Domains & Families for DLEU2 Gene

Gene Families for DLEU2 Gene

Suggested Antigen Peptide Sequences for DLEU2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DLEU2: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for DLEU2 Gene

Function for DLEU2 Gene

Phenotypes for DLEU2 Gene

GenomeRNAi human phenotypes for DLEU2:
genes like me logo Genes that share phenotypes with DLEU2: view

Animal Model Products

miRNA for DLEU2 Gene

miRTarBase miRNAs that target DLEU2

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DLEU2 Gene

Localization for DLEU2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DLEU2 Gene

Pathways & Interactions for DLEU2 Gene

SuperPathways for DLEU2 Gene

No Data Available

Interacting Proteins for DLEU2 Gene

Gene Ontology (GO) - Biological Process for DLEU2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DLEU2 Gene

Drugs & Compounds for DLEU2 Gene

No Compound Related Data Available

Transcripts for DLEU2 Gene

Unigene Clusters for DLEU2 Gene

Deleted in lymphocytic leukemia 2 (non-protein coding):
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for DLEU2 Gene

No ASD Table

Relevant External Links for DLEU2 Gene

GeneLoc Exon Structure for
DLEU2
ECgene alternative splicing isoforms for
DLEU2

Expression for DLEU2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DLEU2 Gene

NURSA nuclear receptor signaling pathways regulating expression of DLEU2 Gene:

DLEU2

SOURCE GeneReport for Unigene cluster for DLEU2 Gene:

Hs.547964
genes like me logo Genes that share expression patterns with DLEU2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DLEU2 Gene

Orthologs for DLEU2 Gene

Evolution for DLEU2 Gene

ENSEMBL:
Gene Tree for DLEU2 (if available)
TreeFam:
Gene Tree for DLEU2 (if available)

No data available for Orthologs for DLEU2 Gene

Paralogs for DLEU2 Gene

No data available for Paralogs for DLEU2 Gene

Variants for DLEU2 Gene

Sequence variations from dbSNP and Humsavar for DLEU2 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1000047936 -- 50,060,562(+) TGAGT(A/G)TCGGG intron-variant
rs1000064639 -- 50,102,336(+) ACCAA(C/T)ATCAG intron-variant
rs1000099372 -- 50,124,300(+) GGAGG(A/G)GGCGG intron-variant
rs1000127350 -- 50,073,878(+) TTAGA(C/T)ATGAA intron-variant
rs1000138122 -- 50,091,495(+) TTCAT(G/T)GTTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DLEU2 Gene

Variant ID Type Subtype PubMed ID
esv1970441 CNV deletion 18987734
esv2085992 CNV deletion 18987734
esv2580955 CNV deletion 19546169
esv2661834 CNV deletion 23128226
esv2666533 CNV deletion 23128226
esv2747402 CNV deletion 23290073
esv2747403 CNV deletion 23290073
esv2747404 CNV deletion 23290073
esv2747405 CNV deletion 23290073
esv3550452 CNV deletion 23714750
esv3550453 CNV deletion 23714750
esv3580637 CNV loss 25503493
esv3632062 CNV loss 21293372
nsv1035151 CNV loss 25217958
nsv1041501 CNV loss 25217958
nsv1054415 CNV loss 25217958
nsv1118263 CNV deletion 24896259
nsv472293 CNV novel sequence insertion 20440878
nsv561618 CNV loss 21841781
nsv64412 CNV deletion 16902084
nsv832608 CNV gain 17160897
nsv951082 CNV duplication 24416366
nsv951083 CNV duplication 24416366

Relevant External Links for DLEU2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DLEU2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DLEU2 Gene

Disorders for DLEU2 Gene

Relevant External Links for DLEU2

Genetic Association Database (GAD)
DLEU2
Human Genome Epidemiology (HuGE) Navigator
DLEU2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DLEU2

No disorders were found for DLEU2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DLEU2 Gene

Publications for DLEU2 Gene

  1. BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31, BCMSUN-like. (PMID: 11072235) Mertens D. … Lichter P. (Int. J. Cancer 2000) 2 3 22 64
  2. Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia. (PMID: 9395242) Liu Y. … Oscier D. (Oncogene 1997) 2 3 22 64
  3. A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample. (PMID: 20451256) Djurovic S. … Andreassen O.A. (J Affect Disord 2010) 3 46 64
  4. Comparative sequence analysis of a region on human chromosome 13q14, frequently deleted in B-cell chronic lymphocytic leukemia, and its homologous region on mouse chromosome 14. (PMID: 11161783) Kapanadze B. … Sangfelt O. (Genomics 2000) 3 22 64
  5. Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1. (PMID: 24885794) Morenos L. … Wong N.C. (Mol. Cancer 2014) 3 64

Products for DLEU2 Gene

Sources for DLEU2 Gene

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