Aliases for DLEC1 Gene
External Ids for DLEC1 Gene
Previous GeneCards Identifiers for DLEC1 Gene
The cytogenetic location of this gene is 3p21.3, and it is located in a region that is commonly deleted in a variety of malignancies. Down-regulation of this gene has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of this gene in tumor cells is a result of aberrant promoter methylation. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins.[provided by RefSeq, Mar 2016]
GeneCards Summary for DLEC1 Gene
DLEC1 (Deleted In Lung And Esophageal Cancer 1) is a Protein Coding gene. Diseases associated with DLEC1 include esophageal cancer and lung cancer. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases.
UniProtKB/Swiss-Prot for DLEC1 Gene
May act as a tumor suppressor by inhibiting cell proliferation.