Aliases for DLEC1 Gene
External Ids for DLEC1 Gene
Previous GeneCards Identifiers for DLEC1 Gene
This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney. [provided by RefSeq, Jul 2008]
GeneCards Summary for DLEC1 Gene
DLEC1 (Deleted In Lung And Esophageal Cancer 1) is a Protein Coding gene. Diseases associated with DLEC1 include esophageal cancer and lung cancer. Among its related pathways are Signaling by GPCR and G-protein signaling_Regulation of CDC42 activity.
UniProtKB/Swiss-Prot for DLEC1 Gene
May act as a tumor suppressor by inhibiting cell proliferation.