Aliases for DISP2 Gene
External Ids for DISP2 Gene
Previous GeneCards Identifiers for DISP2 Gene
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched. [provided by RefSeq, Jul 2008]
GeneCards Summary for DISP2 Gene
DISP2 (Dispatched RND Transporter Family Member 2) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Signaling by Hedgehog. An important paralog of this gene is DISP1.