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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DISP2 Gene

protein-coding   GIFtS: 47
GCID: GC15P040650

Dispatched Homolog 2 (Drosophila)

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dispatched Homolog 2 (Drosophila)1 2
DISPB2 3 5
KIAA17423 5
HsT169082
Dispatched B2
Protein Dispatched Homolog 22

External Ids:    HGNC: 197121   Entrez Gene: 854552   Ensembl: ENSG000001403237   OMIM: 6075035   UniProtKB: A7MBM23   

Export aliases for DISP2 gene to outside databases

Previous GC identifers: GC15P038366 GC15P038437 GC15P017493


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DISP2 Gene:
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures
often depends upon the localized production of secreted protein signals. Cells surrounding the source of a
particular signal respond in a graded manner according to the effective concentration of the signal, and this
response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as
dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh)
signaling. This gene is one of two human homologs of Drosophila dispatched. (provided by RefSeq, Jul 2008)

GeneCards Summary for DISP2 Gene: 
DISP2 (dispatched homolog 2 (Drosophila)) is a protein-coding gene. Diseases associated with DISP2 include gastric cancer, and among its related super-pathways are Hedgehog Signaling Pathway. GO annotations related to this gene include molecular_function. An important paralog of this gene is DISP1.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DISP2 gene promoter:
         E2F-4   E2F-3a   E2F-5   RelA   E2F-2   Nkx2-5   NF-kappaB   E2F-1   E2F   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDISP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for DISP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DISP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q14

DISP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DISP2 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P040650:  view genomic region     (about GC identifiers)

Start:
40,650,434 bp from pter      End:
40,663,257 bp from pter
Size:
12,824 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DISP2_HUMAN, A7MBM2 (See protein sequence)
Recommended Name: Protein dispatched homolog 2  
Size: 1401 amino acids; 152003 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=BAB21833.2; Type=Erroneous termination; Positions=100; Note=Translated as Gln;
Secondary accessions: Q6AHW3 Q9C0C1

Explore the universe of human proteins at neXtProt for DISP2: NX_A7MBM2

Explore proteomics data for DISP2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A7MBM2

  • DISP2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DISP2 Protein Expression
    REFSEQ proteins: NP_277045.1  
    ENSEMBL proteins: 
     ENSP00000267889   ENSP00000453984  

    Human Recombinant Protein Products for DISP2: 
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    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for DISP2
    GenScript Custom Purified and Recombinant Proteins Services for DISP2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DISP2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0016021integral to membrane IEA--

    DISP2 for ontologies           About GeneDecksing



    DISP2 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for DISP2 

    Assay Products for DISP2: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for DISP2 
    Cloud-Clone Corp. CLIAs for DISP2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR000731 SSD

    Graphical View of Domain Structure for InterPro Entry A7MBM2

    ProtoNet protein and cluster: A7MBM2

    UniProtKB/Swiss-Prot: DISP2_HUMAN, A7MBM2
    Similarity: Belongs to the dispatched family
    Similarity: Contains 1 SSD (sterol-sensing) domain


    DISP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    DISP2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DISP2:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DISP2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DISP2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DISP2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DISP2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DISP2
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate DISP2:
    hsa-miR-485-5p hsa-miR-214 hsa-miR-3126-3p hsa-miR-3176 hsa-miR-1207-5p hsa-miR-761 hsa-miR-3922-3p
    SwitchGear 3'UTR luciferase reporter plasmidDISP2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DISP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DISP2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DISP2
    Sirion Biotech Customized adenovirus for overexpression of DISP2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for DISP2 (see all 7)
    OriGene ORF clones in mouse, rat for DISP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DISP2 (NM_033510)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DISP2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DISP2
    Sirion Biotech Customized lentivirus for stable overexpression of DISP2 
                         Customized lentivirus expression plasmids for stable overexpression of DISP2 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for DISP2
    Search LifeMap BioReagents cell lines for DISP2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DISP2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DISP2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Hedgehog Signaling Pathway
    Hedgehog Pathway0.32

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Tocris Bioscience Pathway for DISP2
        Hedgehog Pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DISP2

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007224smoothened signaling pathway NAS16258256

    DISP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DISP2

    Search CenterWatch for drugs/clinical trials and news about DISP2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DISP2 gene: 
    NM_033510.1  

    Unigene Cluster for DISP2:

    Dispatched homolog 2 (Drosophila)
    Hs.355645  [show with all ESTs]
    Unigene Representative Sequence: AB051529
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000267889(uc001zlk.1) ENST00000559721 ENST00000558623
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DISP2
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate DISP2:
    hsa-miR-485-5p hsa-miR-214 hsa-miR-3126-3p hsa-miR-3176 hsa-miR-1207-5p hsa-miR-761 hsa-miR-3922-3p
    SwitchGear 3'UTR luciferase reporter plasmidDISP2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DISP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DISP2
    Clone
    Products:
         
    OriGene clones in human, mouse for DISP2 (see all 7)
    OriGene ORF clones in mouse, rat for DISP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DISP2 (NM_033510)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DISP2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DISP2
    Sirion Biotech Customized lentivirus for stable overexpression of DISP2 
                         Customized lentivirus expression plasmids for stable overexpression of DISP2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for DISP2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DISP2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DISP2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DISP2

    Additional mRNA sequence: 

    AB051529.2 AK096153.1 BC151833.1 CR627480.1 

    4 DOTS entries:

    DT.211569  DT.121074136  DT.211568  DT.121074132 

    12 AceView cDNA sequences:

    BE275044 NM_033510 BQ719867 BM827115 AK096153 BE275836 AB051529 BF955131 
    BE385123 Z40679 Z44922 AK026919 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for DISP2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7
    SP1:                    -                                       
    SP2:                                                            
    SP3:                                                            


    ECgene alternative splicing isoforms for DISP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DISP2 expression in normal human tissues (normalized intensities)      DISP2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCTCTTCAT
    DISP2 Expression
    About this image


    DISP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Pancreas (Endocrine System)    fully expand to see all 4 entries
             Endocrine Progenitor Cells Ventral Pancreatic Bud
     
     Brain (Nervous System)    fully expand to see all 3 entries
             ganglion/cranial/vagus X   
     
     Peripheral Nervous System (Nervous System)
             autonomic/sympathetic/ganglion   
     
     Gut Tube (Gastrointestinal Tract)
             Foregut

    See DISP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DISP2

    SOURCE GeneReport for Unigene cluster: Hs.355645
        SABiosciences Expression via Pathway-Focused PCR Array including DISP2: 
              Hedgehog Signaling Pathway in human mouse rat

    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for DISP2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DISP2
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DISP2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DISP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DISP2 gene from 6/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Disp21 , 5 dispatched homolog 2 (Drosophila)1, 5 79.37(n)1
    76.4(a)1
      2 (59.46 cM)5
    2142401  NM_170593.31  NP_733481.11 
     1187797195 
    chicken
    (Gallus gallus)
    Aves DISP21 dispatched homolog 2 (Drosophila) 60.65(n)
    57.88(a)
      428836  XM_426392.3  XP_426392.3 
    lizard
    (Anolis carolinensis)
    Reptilia DISP26
    Uncharacterized protein
    51(a)
    1 ↔ 1
    GL343264.1(1104980-1139634)
    zebrafish
    (Danio rerio)
    Actinopterygii disp21 dispatched homolog 2 (Drosophila) 52.6(n)
    48.62(a)
      405793  NM_212434.1  NP_997599.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta disp6
    dispatched
    15(a)
    1 → many
    3R(1675416-1682033)
    worm
    (Caenorhabditis elegans)
    Secernentea ptd-26
    che-146
    Protein CHE-14
    13(a)
    13(a)
    many ↔ many
    many ↔ many
    V(9250275-9254223)
    I(5746725-5754278)


    ENSEMBL Gene Tree for DISP2 (if available)
    TreeFam Gene Tree for DISP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DISP2 gene
    DISP12  PTCHD22  
    1 SIMAP similar gene for DISP2 using alignment to 2 protein entries:     DISP2_HUMAN (see all proteins):
    DISP1

    DISP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/428 SNPs in DISP2 are shown (see all 428)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1821397671,2
    --40649150(+) AGGTCC/TTTCCT 1 -- us2k10--------
    rs1855834401,2
    --40649269(+) TTCAGC/GGCAGA 1 -- us2k10--------
    rs1438707441,2
    --40649270(+) TCAGGA/GCAGAC 1 -- us2k10--------
    rs1161020531,2
    F--40649321(+) TATGAC/TCTGTG 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs284765961,2
    F--40649376(+) GTCCAA/GGTGTT 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1900916051,2
    --40649492(+) ATCCCA/GCATCC 1 -- us2k10--------
    rs45754961,2
    C,F,A,H--40649590(+) GTCCAT/CCATAC 1 -- us2k123Minor allele frequency- C:0.25NS EA NA WA CSA 2351
    rs714724331,2
    C,F--40649609(+) GCTCTA/CCTCAC 1 -- us2k17Minor allele frequency- C:0.18NA WA CSA EA 366
    rs80333031,2
    C,F--40649700(+) GGGCAC/TCTCCC 1 -- us2k13Minor allele frequency- T:0.07NA EA 242
    rs1838183091,2
    --40649845(+) TATAAA/GCCTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DISP2 (40650434 - 40663257 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for DISP2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv510660CNV Loss20534489
    esv34145CNV Loss18971310
    nsv820173CNV Gain19587683

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DISP2
    DNA2.0 Custom Variant and Variant Library Synthesis for DISP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607503    OMIM disorders: --

    2 diseases for DISP2:    About MalaCards
    gastric cancer    


    DISP2 for disorders           About GeneDecksing


    Export disorders for DISP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DISP2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with DISP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. Dispatched, a novel sterol-sensing domain protein ded icated to the release of cholesterol-modified hedgehog from signaling cells. (PubMed id 10619433)1, 3 Burke R....Basler K. (1999)
    3. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    4. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
    5. Hedgehog signaling pathway and gastric cancer. (PubMed id 16258256)1 Katoh Y. and Katoh M. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    8. Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. (PubMed id 12372301)1 Ma Y....Beachy P.A. (2002)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)2 Nakajima D.... Nagase T. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 85455 HGNC: 19712 AceView: DISP2 Ensembl:ENSG00000140323 euGenes: HUgn85455
    ECgene: DISP2 H-InvDB: DISP2

    (According to HUGE)
    About This Section
    HUGE: KIAA1742

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DISP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DISP2 gene:
    Search GeneIP for patents involving DISP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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