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Aliases for DISC2 Gene

Subcategory (RNA class) for DISC2 Gene

non-coding RNA

Quality Score for this RNA gene is

2

Aliases for DISC2 Gene

  • Disrupted In Schizophrenia 2 (Non-Protein Coding) 2 3
  • DISC1 Antisense RNA 1 2 3
  • Non-Protein Coding RNA 15 2
  • DISC1 Opposite Strand 3
  • NCRNA00015 3
  • DISC1-AS1 3
  • DISC1OS 3

External Ids for DISC2 Gene

Previous GeneCards Identifiers for DISC2 Gene

  • GC01U990288
  • GC01M230016
  • GC01M231950

Summaries for DISC2 Gene

Entrez Gene Summary for DISC2 Gene

  • DISC2 is thought to specify a noncoding RNA molecule antisense to DISC1 (MIM 605210). Both genes were found to be disrupted by a translocation in a large schizophrenia (MIM 181500) kindred.[supplied by OMIM, Jul 2002]

GeneCards Summary for DISC2 Gene

DISC2 (Disrupted In Schizophrenia 2 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with DISC2 include schizophrenia.

Gene Wiki entry for DISC2 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DISC2 Gene

Genomics for DISC2 Gene

Regulatory Elements for DISC2 Gene

Genomic Location for DISC2 Gene

Start:
231,814,626 bp from pter
End:
231,818,517 bp from pter
Size:
3,892 bases
Orientation:
Minus strand

Genomic View for DISC2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DISC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DISC2 Gene

Proteins for DISC2 Gene

Post-translational modifications for DISC2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DISC2 Gene

Domains for DISC2 Gene

Gene Families for DISC2 Gene

HGNC:
  • LNCRNA :Long non-coding RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DISC2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for DISC2 Gene

Function for DISC2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DISC2 Gene

Localization for DISC2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DISC2 Gene

Pathways for DISC2 Gene

SuperPathways for DISC2 Gene

No Data Available

Interacting Proteins for DISC2 Gene

Gene Ontology (GO) - Biological Process for DISC2 Gene

None

No data available for Pathways by source for DISC2 Gene

Transcripts for DISC2 Gene

mRNA/cDNA for DISC2 Gene

(1) Additional mRNA sequences :

Unigene Clusters for DISC2 Gene

Disrupted in schizophrenia 2 (non-protein coding):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DISC2

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DISC2 Gene

No ASD Table

Relevant External Links for DISC2 Gene

GeneLoc Exon Structure for
DISC2
ECgene alternative splicing isoforms for
DISC2

Expression for DISC2 Gene

SOURCE GeneReport for Unigene cluster for DISC2 Gene Hs.720568

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for DISC2 Gene

Orthologs for DISC2 Gene

No data available for Orthologs and Evolution for DISC2 Gene

Paralogs for DISC2 Gene

No data available for Paralogs for DISC2 Gene

Variants for DISC2 Gene

Structural Variations from Database of Genomic Variants (DGV) for DISC2 Gene

Variant ID Type Subtype PubMed ID
nsv873300 CNV Loss 21882294

Relevant External Links for DISC2 Gene

HapMap Linkage Disequilibrium report
DISC2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for DISC2 Gene

Disorders for DISC2 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for DISC2 Gene in MalaCards »

(1) Diseases for DISC2 Gene including...

(1) OMIM Diseases for DISC2 Gene (606271)

Relevant External Links for DISC2

Genetic Association Database (GAD)
DISC2
Human Genome Epidemiology (HuGE) Navigator
DISC2
genes like me logo Genes that share disorders with DISC2: view

No data available for UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for DISC2 Gene

Publications for DISC2 Gene

  1. Disruption of two novel genes by a schizophrenia-linked translocation. (PMID: 10814723) Millar J.K. … Porteous D.J. (Hum. Mol. Genet. 2000) 2 3
  2. DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness. (PMID: 15478311) Millar J.K. … Thomson P.A. (Ann. Med. 2004) 2 3
  3. Genome-wide association of lipid-lowering response to statins in combined study populations. (PMID: 20339536) Barber M.J. … Krauss R.M. (PLoS ONE 2010) 3 48
  4. Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency. (PMID: 20694011) Ferreira R.C. … HammarstrAPm L. (Nat. Genet. 2010) 48
  5. The DISC locus in psychiatric illness. (PMID: 17912248) Chubb J.E. … Millar J.K. (Mol. Psychiatry 2008) 3

Products for DISC2 Gene

Sources for DISC2 Gene

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