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Aliases for DISC2 Gene

Subcategory (RNA class) for DISC2 Gene

non-coding RNA

Quality Score for this RNA gene is

2

Aliases for DISC2 Gene

  • Disrupted In Schizophrenia 2 (Non-Protein Coding) 2 3
  • DISC1 Antisense RNA 1 2 3
  • Non-Protein Coding RNA 15 2
  • DISC1 Opposite Strand 3
  • NCRNA00015 3
  • DISC1-AS1 3
  • DISC1OS 3

External Ids for DISC2 Gene

Previous GeneCards Identifiers for DISC2 Gene

  • GC01U990288
  • GC01M230016
  • GC01M231950

Summaries for DISC2 Gene

Entrez Gene Summary for DISC2 Gene

  • DISC2 is thought to specify a noncoding RNA molecule antisense to DISC1 (MIM 605210). Both genes were found to be disrupted by a translocation in a large schizophrenia (MIM 181500) kindred.[supplied by OMIM, Jul 2002]

GeneCards Summary for DISC2 Gene

DISC2 (Disrupted In Schizophrenia 2 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with DISC2 include schizophrenia.

Gene Wiki entry for DISC2 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DISC2 Gene

Genomics for DISC2 Gene

Regulatory Elements for DISC2 Gene

Genomic Location for DISC2 Gene

Chromosome:
1
Start:
231,814,626 bp from pter
End:
231,818,517 bp from pter
Size:
3,892 bases
Orientation:
Minus strand

Genomic View for DISC2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for DISC2 Gene

Proteins for DISC2 Gene

Post-translational modifications for DISC2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DISC2 Gene

Domains & Families for DISC2 Gene

Gene Families for DISC2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DISC2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for DISC2 Gene

Function for DISC2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DISC2 Gene

Localization for DISC2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DISC2 Gene

Pathways & Interactions for DISC2 Gene

SuperPathways for DISC2 Gene

No Data Available

Interacting Proteins for DISC2 Gene

Gene Ontology (GO) - Biological Process for DISC2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DISC2 Gene

Drugs & Compounds for DISC2 Gene

No Compound Related Data Available

Transcripts for DISC2 Gene

mRNA/cDNA for DISC2 Gene

(1) Additional mRNA sequences :

Unigene Clusters for DISC2 Gene

Disrupted in schizophrenia 2 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DISC2 Gene

No ASD Table

Relevant External Links for DISC2 Gene

GeneLoc Exon Structure for
DISC2
ECgene alternative splicing isoforms for
DISC2

Expression for DISC2 Gene

SOURCE GeneReport for Unigene cluster for DISC2 Gene Hs.720568

No Expression Related Data Available

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for DISC2 Gene

Orthologs for DISC2 Gene

No data available for Orthologs and Evolution for DISC2 Gene

Paralogs for DISC2 Gene

No data available for Paralogs for DISC2 Gene

Variants for DISC2 Gene

Structural Variations from Database of Genomic Variants (DGV) for DISC2 Gene

Variant ID Type Subtype PubMed ID
nsv873300 CNV Loss 21882294

Relevant External Links for DISC2 Gene

HapMap Linkage Disequilibrium report
DISC2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for DISC2 Gene

Disorders for DISC2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for DISC2 Gene - From: OMIM, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
schizophrenia
  • schizophrenia 12
- elite association
Search DISC2 in MalaCards View complete list of genes associated with diseases

Relevant External Links for DISC2

Genetic Association Database (GAD)
DISC2
Human Genome Epidemiology (HuGE) Navigator
DISC2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DISC2
genes like me logo Genes that share disorders with DISC2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DISC2 Gene

Publications for DISC2 Gene

  1. DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness. (PMID: 15478311) Millar J.K. … Thomson P.A. (Ann. Med. 2004) 2 67
  2. Disruption of two novel genes by a schizophrenia-linked translocation. (PMID: 10814723) Millar J.K. … Porteous D.J. (Hum. Mol. Genet. 2000) 2 67
  3. lncRNAdb: a reference database for long noncoding RNAs. (PMID: 21112873) Amaral P.P. … Mattick J.S. (Nucleic Acids Res. 2011) 67
  4. Genome-wide association of lipid-lowering response to statins in combined study populations. (PMID: 20339536) Barber M.J. … Krauss R.M. (PLoS ONE 2010) 67
  5. Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency. (PMID: 20694011) Ferreira R.C. … HammarstrAPm L. (Nat. Genet. 2010) 67

Products for DISC2 Gene

Sources for DISC2 Gene

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