DIS3L2 Gene
protein-coding GIFtS: 50
GCID: GC02P232825
|
|
DIS3 mitotic control homolog (S. cerevisiae)-like 2(Previous names: family with sequence similarity 6, member A )
(Previous symbol: FAM6A)
| |
Aliases
for DIS3L2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 21 2 | | PRLMNS2 | | FAM6A1 2 3 | | DIS3-Like Exonuclease 22 | | Family With Sequence Similarity 6, Member A1 2 | | EC 3.1.13.-3 | | FLJ369741 | | EC 3.1.138 | | MGC421741 | | |
Export aliases for DIS3L2 gene to outside databasesPrevious GC identifers: GC02P232537 GC02P224677 |
Summaries
for DIS3L2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DIS3L2:
The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. Theexosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Severaltranscript variants, some protein-coding and some not, have been found for this gene. (provided by RefSeq, Mar 2012)
UniProtKB/Swiss-Prot: DI3L2_HUMAN, Q8IYB7Function: Ribonuclease that plays a critical role in RNA metabolism. It is essential for correct mitosis, andnegatively regulates cell proliferation
|
Genomic Views
for DIS3L2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DIS3L2 gene promoter:
STAT1 AML1a HSF1 (long) STAT1beta AP-4 STAT1alpha YY1 c-Myb FOXO1a FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for DIS3L2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DIS3L2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q37.1 Ensembl cytogenetic band: 2q37.1 HGNC cytogenetic band: 2q37.1DIS3L2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P232825: view genomic region
(about GC identifiers)
Start:
|
232,825,955 bp from pter |
End:
|
233,209,060 bp from pter |
Size:
|
383,106 bases |
Orientation:
|
plus strand |
|
Proteins
for DIS3L2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DI3L2_HUMAN, Q8IYB7 (See
protein sequence)Recommended Name: DIS3-like exonuclease 2 Size: 885 amino acids; 99279 Da
Subcellular location: Cytoplasm
Caution: Although assigned as two separate genes (DIS3L2 and FAM6A), it is quite clear that the gene FAM6A described byPubMed:11352565 is a fragmentary prediction of DIS3L2
Secondary accessions: Q53S79 Q580W6 Q5XKH0 Q69YG5 Q6AW99 Q7Z4T6 Q8N9K9Alternative splicing: 5 isoforms: Q8IYB7-1 Q8IYB7-2 Q8IYB7-3 Q8IYB7-4 Q8IYB7-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DIS3L2: NX_Q8IYB7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IYB7
4 DME Specific Peptides for DIS3L2 (Q8IYB7)
DIS3L2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001244210.1 NP_001244211.1 NP_689596.4
ENSEMBL proteins: ENSP00000273009 ENSP00000386594 ENSP00000374655 ENSP00000388999 ENSP00000390467 ENSP00000386799 ENSP00000391175 ENSP00000415419 ENSP00000392754 ENSP00000401700 ENSP00000408764 ENSP00000315569 ENSP00000353584
Human Recombinant Protein Products for DIS3L2:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IDA | -- |
DIS3L2 for ontologies About GeneDecksing
DIS3L2 Antibody Products:
Assay Products for DIS3L2: |
Protein
Domains /
Families
for DIS3L2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DIS3L2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IYB7ProtoNet protein and cluster: Q8IYB7 UniProtKB/Swiss-Prot: DI3L2_HUMAN, Q8IYB7Similarity: Belongs to the RNR ribonuclease family |
Function
for DIS3L2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: DI3L2_HUMAN, Q8IYB7Function: Ribonuclease that plays a critical role in RNA metabolism. It is essential for correct mitosis, andnegatively regulates cell proliferation Enzyme Numbers (IUBMB): EC 3.1.13.-1 EC 3.1.132
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
DIS3L2 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L2 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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Synthesis Service for DIS3L2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DIS3L2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DIS3L2 |
|
Pathways & Interactions
for DIS3L2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DIS3L2
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5/7 Interacting proteins for DIS3L2 (Q8IYB72, 3 ENSP000003155694) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007067 | mitosis |
IMP | -- | | GO:0008285 | negative regulation of cell proliferation |
IMP | -- | | GO:0051301 | cell division |
IEA | -- | | GO:0051306 | mitotic sister chromatid separation |
IMP | -- |
DIS3L2 for ontologies About GeneDecksing
|
Drugs & Compounds
for DIS3L2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DIS3L2
Search CenterWatch for drugs/clinical trials and news about DIS3L2 / DI3L2
|
Transcripts
for DIS3L2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DIS3L2 gene (3 alternative transcripts): NM_001257281.1 NM_001257282.1 NM_152383.4 Unigene Cluster for DIS3L2: DIS3 mitotic control homolog (S. cerevisiae)-like 2 Hs.732236 [show with all ESTs]Unigene Representative Sequence: AL83417417 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000273009 ENST00000409401 ENST00000390005 ENST00000445090 ENST00000441279
ENST00000409307 ENST00000433430(uc002vso.3) ENST00000464554 ENST00000470087
ENST00000424049 ENST00000498319 ENST00000429283 ENST00000434477 ENST00000418143
ENST00000417808 ENST00000325385(uc010fxz.3 uc002vsm.4) ENST00000360410
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L2 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DIS3L2 (NM_152383) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DIS3L2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DIS3L2 |
Additional cDNA sequence: AF443854.1 AK094293.1 AK295363.1 AL834174.1 BC026166.1 BC030113.2 BC036113.1 BX648325.1 NR_046476.1 NR_046477.1 13 DOTS entries: DT.86821189 DT.100782363 DT.91935067 DT.101978398 DT.454924 DT.95373257 DT.121005994 DT.40218109 DT.86852494 DT.100782362 DT.100782364 DT.121005980 DT.95311756 24/109 AceView cDNA sequences (see all 109): BQ954228 BX382985 BE791331 CD251979 AI493578 AK090419 BX377429 BQ717073 AL834174 BG746662 BM128893 AW629200 CA396505 AI650526 BM128478 CR590558 BU623441 AL044909 AW589919 BQ071152 AW235225 AK094293 CD692148 CR598716
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for DIS3L2 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18a | · | 18b | ^ | 19a | · | 19b | ^ | 20 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for DIS3L2
|
Expression
for DIS3L2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DIS3L2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGCAGGAGC
About this image
See DIS3L2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DIS3L2
SOURCE GeneReport for Unigene cluster: Hs.732236
SABiosciences Custom PCR Arrays for DIS3L2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DIS3L2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DIS3L2 |
Orthologs
for DIS3L2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for DIS3L2 gene from 9/33 species (see all 33) About this table
ENSEMBL Gene Tree for DIS3L2 (if available)
TreeFam Gene Tree for DIS3L2 (if available) |
Paralogs
for DIS3L2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DIS3L2 gene
- DIS3L2 DIS32
2 SIMAP similar genes for DIS3L2 using alignment to 6 protein entries: DI3L2_HUMAN (see all proteins):FLJ00327 DIS3
DIS3L2 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for DIS3L2
PGOHUM00000241138 PGOHUM00000241139 PGOHUM00000241140 PGOHUM00000241141 PGOHUM00000241142
|
Genomic Variants
for DIS3L2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: DI3L2_HUMAN, Q8IYB7Polymorphism: Disrupted by a t(2;7)(q37.1;q21.3) chromosomal translocation found in a patient suffering from Marfanoidhabitus and skeletal anomalies. However, its absence does not seem to be the cause of the disease
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DIS3L2 (232825955 - 233075955 bp, first 250kb of DIS3L2)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for DIS3L2
7 CNVs: 44018 50413 90335 50412 8398 3408 98168
1 Indel: 60353
Human Gene Mutation Database (HGMD): DIS3L2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DIS3L2 |
|
Disorders
/ Diseases
for DIS3L2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DIS3L2 for disorders About GeneDecksing
OMIM gene information: 614184
OMIM disorders: --
UniProtKB/Swiss-Prot: DI3L2_HUMAN, Q8IYB7
Defects in DIS3L2 are the cause of Perlman syndrome (PRLMNS) [MIM:267000]. An autosomal recessive congenitalovergrowth syndrome. Affected children are large at birth, are hypotonic, and show organomegaly, characteristic facialdysmorphisms (inverted V-shaped upper lip, prominent forehead, deep-set eyes, broad and flat nasal bridge, and low-setears), renal anomalies (nephromegaly and hydronephrosis), frequent neurodevelopmental delay, and high neonatalmortality. Perlman syndrome is associated with a high risk of Wilms tumor. Histologic examination of the kidneys inaffected children shows frequent nephroblastomatosis, which is a precursor lesion for Wilms tumor
4  diseases for DIS3L2: About MalaCardspneumonia malaria overgrowth syndrome wilms tumor
Human Genome Epidemiology (HuGE) Navigator: DIS3L2 (1 document)
Export disorders for DIS3L2 gene to outside databases
|
Publications
for DIS3L2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DIS3L2 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with DIS3L2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. (PubMed id 22306653)1, 2, 3 Astuti D.... Maher E.R. (2012)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Complex arrangement of genes within a 220-kb region of double- duplicated DNA on human 2q37.1. (PubMed id 11352565)1, 2 Rump A.... Rosenthal A. (2001)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- A genome-wide association study in 19 633 Japanese su bjects identified LHX3-QSOX2 and IGF1 as adult height loci. (PubMed id 20189936)1 Okada Y....Kamatani N. (2010)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- A genome-wide association study of northwestern Europ eans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. (PubMed id 19570815)1 Estrada K....Kayser M. (2009)
|
External Searches for DIS3L2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DIS3L2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DIS3L2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DIS3L2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DIS3L2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DIS3L2 gene:
Search GeneIP for patents involving DIS3L2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DIS3L2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DIS3L2 |
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