DIS3L Gene
protein-coding GIFtS: 51
GCID: GC15P066585
|
|
DIS3 mitotic control homolog (S. cerevisiae)-like
| |
Aliases
for DIS3L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like1 2 | | MGC45621 | | KIAA19551 3 | | DIS3-Like Exonuclease 12 | | DIS3L12 3 | | EC 3.1.13.-3 | | FLJ380881 | | EC 3.1.138 |
Export aliases for DIS3L gene to outside databasesPrevious GC identifers: GC15P064373 GC15P043422 |
Summaries
for DIS3L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: DI3L1_HUMAN, Q8TF46Function: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonucleaseactivity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNAexosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containingAU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translationof aberrant mRNAs. It seems to be involved in degradation of histone mRNA
Gene Wiki entry for DIS3L
|
Genomic Views
for DIS3L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DIS3L gene promoter:
S8 Sox5 HFH-1 Lmo2 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for DIS3L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DIS3L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q22.31 Ensembl cytogenetic band: 15q22.31 HGNC cytogenetic band: 15q22.31DIS3L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P066585: view genomic region
(about GC identifiers)
Start:
|
66,585,555 bp from pter |
End:
|
66,626,236 bp from pter |
Size:
|
40,682 bases |
Orientation:
|
plus strand |
|
Proteins
for DIS3L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DI3L1_HUMAN, Q8TF46 (See
protein sequence)Recommended Name: DIS3-like exonuclease 1 Size: 1054 amino acids; 120787 Da
Cofactor: Magnesium
Subunit: Component of the RNA exosome complex. The catalytically inactive RNA exosome core (Exo-9) complex is believedto associate with catalytic subunits EXOSC10, and DIS3 or DIS3L in cytoplasmic- and nuclear-specific RNA exosomecomplex forms
Subcellular location: Cytoplasm
Sequence caution: Sequence=BAB85541.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q8N1N8 Q8WTU9 Q96CM7Alternative splicing: 4 isoforms: Q8TF46-1 Q8TF46-2 Q8TF46-3 Q8TF46-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DIS3L: NX_Q8TF46
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TF46
4/28 DME Specific Peptides for DIS3L (Q8TF46) (see all 28)
DIS3L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001137160.1 NP_588616.1
ENSEMBL proteins: ENSP00000321583 ENSP00000435792 ENSP00000433504 ENSP00000321711 ENSP00000432125 ENSP00000436583 ENSP00000436573 ENSP00000432407 ENSP00000388980
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
DIS3L for ontologies About GeneDecksing
DIS3L Antibody Products:
Assay Products for DIS3L: |
Protein
Domains /
Families
for DIS3L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DIS3L for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8TF46ProtoNet protein and cluster: Q8TF46 1 Blocks protein family: IPB001900 Ribonuclease II
UniProtKB/Swiss-Prot: DI3L1_HUMAN, Q8TF46Similarity: Belongs to the RNR ribonuclease family |
Function
for DIS3L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DI3L1_HUMAN, Q8TF46Function: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonucleaseactivity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNAexosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containingAU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translationof aberrant mRNAs. It seems to be involved in degradation of histone mRNAEnzyme Numbers (IUBMB): EC 3.1.13.-1 EC 3.1.132
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): DIS3L (NM_001143688) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DIS3L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DIS3L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DIS3L |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
DIS3L for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for DIS3L:
|
Pathways & Interactions
for DIS3L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DIS3L
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
5/26 Interacting proteins for DIS3L (Q8TF461, 2, 3 ENSP000003217114) via UniProtKB, MINT, STRING, and/or I2D (see all 26)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016075 | rRNA catabolic process |
IMP | -- |
DIS3L for ontologies About GeneDecksing
|
Drugs & Compounds
for DIS3L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DIS3L
Search CenterWatch for drugs/clinical trials and news about DIS3L / DI3L1
|
Transcripts
for DIS3L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DIS3L gene (2 alternative transcripts): NM_001143688.1 NM_133375.3 Unigene Cluster for DIS3L: DIS3 mitotic control homolog (S. cerevisiae)-like Hs.446251 [show with all ESTs]Unigene Representative Sequence: NM_00114368815 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000319194(uc010ujl.1 uc002app.3 uc010bho.3) ENST00000525134
ENST00000524795 ENST00000565281 ENST00000319212(uc010ujm.2) ENST00000564909(uc002apq.2)
ENST00000525109 ENST00000532580 ENST00000532293 ENST00000530615 ENST00000530537
ENST00000562314 ENST00000564945 ENST00000568874 ENST00000441424
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): DIS3L (NM_001143688) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DIS3L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DIS3L |
Additional cDNA sequence: AB075835.1 AK095407.1 AK123202.1 AK295392.1 BC014124.2 BC022089.2 12 DOTS entries: DT.97842322 DT.92419777 DT.100779083 DT.121067801 DT.121067836 DT.101968464 DT.121067845 DT.40207844 DT.95267271 DT.75147816 DT.95134264 DT.95246224 24/104 AceView cDNA sequences (see all 104): AI460036 BM480303 BX091524 BC014124 BM667083 AA665192 CB132382 AW675272 NM_133375 BU173770 BF968274 AV703252 BC022089 AK095407 BU179361 BG028689 BP337679 AI352615 BP360644 BQ948533 CA396619 BP340216 AI184226 BF855707
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for DIS3L (see all 11) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15 | ^ | 16a | · | 16b | ^ |
|---|
|
| SP1: | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 17 | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | - | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for DIS3L
|
Expression
for DIS3L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DIS3L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAACCGTAAG
About this image
See DIS3L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DIS3L
SOURCE GeneReport for Unigene cluster: Hs.446251
SABiosciences Custom PCR Arrays for DIS3L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DIS3L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DIS3L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DIS3L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DIS3L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DIS3L |
Orthologs
for DIS3L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for DIS3L gene from 8/24 species (see all 24) About this table
ENSEMBL Gene Tree for DIS3L (if available)
TreeFam Gene Tree for DIS3L (if available) |
Paralogs
for DIS3L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DIS3L gene
- DIS32 DIS3L22
2 SIMAP similar genes for DIS3L using alignment to 8 protein entries: DI3L1_HUMAN (see all proteins):FLJ00327 DIS3
DIS3L for paralogs About GeneDecksing
|
Genomic Variants
for DIS3L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DIS3L (66585555 - 66626236 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DIS3L: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DIS3L |
|
Disorders
/ Diseases
for DIS3L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DIS3L for disorders About GeneDecksing
OMIM gene information: 614183
OMIM disorders: --
2  diseases for DIS3L: About MalaCardspneumonia malaria
Export disorders for DIS3L gene to outside databases
|
Publications
for DIS3L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DIS3L gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with DIS3L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L. (PubMed id 20531386)1, 2, 3 Tomecki R....Jensen T.H. (2010)
- Dis3-like 1: a novel exoribonuclease associated with the human exosome. (PubMed id 20531389)1, 2 Staals R.H....Pruijn G.J. (2010)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PubMed id 11853319)1, 2 Nagase T.... Ohara O. (2001)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
|
External Searches for DIS3L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DIS3L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DIS3L gene
(According to HUGE)
About This Section
| |
Specialized Databases showing DIS3L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DIS3L | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DIS3L gene:
Search GeneIP for patents involving DIS3L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DIS3L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DIS3L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DIS3L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DIS3L | | | OriGene Protein Over-expression Lysate for DIS3L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DIS3L | | OriGene 3'-UTR Clone for DIS3L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DIS3L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for DIS3L | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DIS3L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DIS3L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DIS3L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DIS3L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DIS3L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DIS3L |
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| | | | Search Tocris compounds for DIS3L |
| |  |  |  |  | | | | |
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 | | | DIS3L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DIS3L |
|  |  |  | | | | ThermoFisher Antibodies for DIS3L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DIS3L |
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