Aliases for DIRAS3 Gene
External Ids for DIRAS3 Gene
Previous HGNC Symbols for DIRAS3 Gene
Previous GeneCards Identifiers for DIRAS3 Gene
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015]
GeneCards Summary for DIRAS3 Gene
DIRAS3 (DIRAS Family GTP Binding RAS Like 3) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Development EGFR signaling pathway. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAP2B.