Aliases for DIRAS3 Gene
External Ids for DIRAS3 Gene
Previous HGNC Symbols for DIRAS3 Gene
Previous GeneCards Identifiers for DIRAS3 Gene
This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. [provided by RefSeq, Oct 2010]
GeneCards Summary for DIRAS3 Gene
DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3) is a Protein Coding gene. Among its related pathways are RhoGDI Pathway and Akt Signaling. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAP2B.