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DIRAS2 Gene

protein-coding   GIFtS: 50
GCID: GC09M093405

DIRAS Family, GTP-Binding RAS-Like 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DIRAS Family, GTP-Binding RAS-Like 21 2
Distinct Subgroup Of The Ras Family Member 22 3
Di-Ras22
GTP-Binding Protein Di-Ras22

External Ids:    HGNC: 193231   Entrez Gene: 547692   Ensembl: ENSG000001650237   OMIM: 6078635   UniProtKB: Q96HU83   

Export aliases for DIRAS2 gene to outside databases

Previous GC identifers: GC09M085101 GC09M086672 GC09M088716 GC09M088717 GC09M090451 GC09M092411 GC09M093373 GC09M063052 GC09M093374 GC09M093379 GC09M093391


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DIRAS2 Gene:
DIRAS2 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of
monomeric GTPases.(supplied by OMIM, Apr 2004)

GeneCards Summary for DIRAS2 Gene:
DIRAS2 (DIRAS family, GTP-binding RAS-like 2) is a protein-coding gene. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAP2C.

UniProtKB/Swiss-Prot: DIRA2_HUMAN, Q96HU8
Function: Displays low GTPase activity and exist predominantly in the GTP-bound form




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NC_018920.2  NT_008470.20  
Regulatory elements:
   Search for regulatory transcription factor binding sites for DIRAS2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDIRAS2 promoter sequence
   Search Chromatin IP Primers for DIRAS2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DIRAS2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.2   Ensembl cytogenetic band:  9q22.2   HGNC cytogenetic band: 9q22.32

DIRAS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DIRAS2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M093405:  view genomic region     (about GC identifiers)

Start:
93,372,114 bp from pter      End:
93,405,386 bp from pter
Size:
33,273 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: DIRA2_HUMAN, Q96HU8 (See protein sequence)
Recommended Name: GTP-binding protein Di-Ras2 precursor  
Size: 199 amino acids; 22485 Da
1 PDB 3D structure from and Proteopedia for DIRAS2:
2ERX (3D)    
Secondary accessions: B3KVM2

Explore the universe of human proteins at neXtProt for DIRAS2: NX_Q96HU8

Explore proteomics data for DIRAS2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DIRAS2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060064.2  
    ENSEMBL proteins: 
     ENSP00000364919  

    DIRAS2 Human Recombinant Protein Products:

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    antibodies-online peptides for DIRAS2

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    antibodies-online antibodies for DIRAS2 (19 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR027417 P-loop_NTPase
     IPR020849 Small_GTPase_Ras

    Graphical View of Domain Structure for InterPro Entry Q96HU8

    ProtoNet protein and cluster: Q96HU8

    2 Blocks protein domains:
    IPB001806 Transforming protein P21 RAS signature
    IPB003577 Ras small GTPase


    UniProtKB/Swiss-Prot: DIRA2_HUMAN, Q96HU8
    Similarity: Belongs to the small GTPase superfamily. Di-Ras family


    Find genes that share domains with DIRAS2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DIRA2_HUMAN, Q96HU8
    Function: Displays low GTPase activity and exist predominantly in the GTP-bound form

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005525GTP binding IDA12194967
    GO:0051019NOT mitogen-activated protein kinase binding IPI12194967
         
    Find genes that share ontologies with DIRAS2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for DIRAS2:
     Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for DIRAS2

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    Selected qRT-PCR Assays for microRNAs that regulate DIRAS2 (see all 64):
    hsa-miR-607 hsa-miR-765 hsa-miR-128 hsa-miR-218 hsa-miR-548l hsa-miR-374c hsa-miR-186 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidDIRAS2 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DIRA2_HUMAN, Q96HU8: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    extracellular2
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005886plasma membrane IDA12194967
    GO:0016020membrane ----

    Find genes that share ontologies with DIRAS2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DIRAS2
    Interactions:

        Search GeneGlobe Interaction Network for DIRAS2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for DIRAS2 (Q96HU83 ENSP000003649194) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM1P621583, ENSP000003494674I2D: score=1 STRING: ENSP00000349467
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    YWHABP319463I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process IEA--
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0015031protein transport ----
    GO:0043406NOT positive regulation of MAP kinase activity IDA12194967

    Find genes that share ontologies with DIRAS2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DIRAS2 (DIRA2)

    1 HMDB Compound for DIRAS2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DIRAS2 gene: 
    NM_017594.3  

    Unigene Cluster for DIRAS2:

    DIRAS family, GTP-binding RAS-like 2
    Hs.165636  [show with all ESTs]
    Unigene Representative Sequence: NM_017594
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000375765(uc004aqx.1)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate DIRAS2 (see all 64):
    hsa-miR-607 hsa-miR-765 hsa-miR-128 hsa-miR-218 hsa-miR-548l hsa-miR-374c hsa-miR-186 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidDIRAS2 3' UTR sequence
    Inhib. RNA
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DIRAS2
      QuantiTect SYBR Green Assays in human, mouse, rat DIRAS2
      QuantiFast Probe-based Assays in human, mouse, rat DIRAS2

    Additional mRNA sequence: 

    AB076889.1 AK122986.1 AK124628.1 AL137308.1 BC008065.2 

    7 DOTS entries:

    DT.308389  DT.101973914  DT.121173410  DT.121173429  DT.70100284  DT.70103487  DT.121173371 

    Selected AceView cDNA sequences (see all 59):

    BP360709 AI266194 NM_017594 BX105476 AB076889 AW264190 BC008065 CK300867 
    AA084085 AK122986 AI249696 AK124628 BE206376 BM722569 R47868 BM679220 
    AA321982 BM671331 BM692773 BX509615 H29469 AI393851 AA325427 R47867 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for DIRAS2    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d
    SP1:                    -           -                           
    SP2:                    -                                       
    SP3:                    -     -     -                           
    SP4:                          -     -                           


    ECgene alternative splicing isoforms for DIRAS2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DIRAS2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTTTATAT
    DIRAS2 Expression
    About this image


    DIRAS2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Limb (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Adipose (Muscoskeletal System)
             Visceral White Adipocytes Visceral White Adipose
     
     Skeletal Muscle (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
    DIRAS2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DIRAS2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.165636

    UniProtKB/Swiss-Prot: DIRA2_HUMAN, Q96HU8
    Tissue specificity: Highly expressed in brain

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DIRAS2 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Diras21 , 5 DIRAS family, GTP-binding RAS-like 21, 5 91.29(n)1
    98.99(a)1
      13 (27.30 cM)5
    682031  NM_001024474.21  NP_001019645.11 
     525043755 
    chicken
    (Gallus gallus)
    Aves DIRAS21 DIRAS family, GTP-binding RAS-like 2 80.57(n)
    93.47(a)
      425241  XM_004949251.1  XP_004949308.1 
    lizard
    (Anolis carolinensis)
    Reptilia DIRAS26
    DIRAS family, GTP-binding RAS-like 2
    90(a)
    1 ↔ 1
    2(32192544-32193191)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia diras21 DIRAS family, GTP-binding RAS-like 2 77.39(n)
    92.96(a)
      100038204  XM_002937026.2  XP_002937072.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5609401 GTP-binding protein Di-Ras2-like 81.07(n)
    89.45(a)
      560940  XM_005155552.1  XP_005155609.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG85001 CG8500 70.83(n)
    77.6(a)
      41203  NM_141691.2  NP_649948.1 
    worm
    (Caenorhabditis elegans)
    Secernentea drn-16
    Protein DRN-1 (drn-1) mRNA, complete cds
    52(a)
    1 → many
    II(5270366-5271824) WBGene00016911


    ENSEMBL Gene Tree for DIRAS2 (if available)
    TreeFam Gene Tree for DIRAS2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DIRAS2 gene
    RAP2C2  RASL10B2  DIRAS12  RAP1B2  RASD22  RIT22  RAP2A2  RIT12  
    RAP1A2  RAP2B2  RASD12  RASL10A2  DIRAS32  
    Selected SIMAP similar genes for DIRAS2 using alignment to 2 protein entries:     DIRA2_HUMAN (see all proteins) (see all similar genes):
    DIRAS1    RAP2A    DKFZp547A0616    RAP2B    RAP2C    RAP1B
    DIRAS3    RAP1A    HRAS    c-bas/has    RHEB    RASD2
    RHEBL1    KRAS    RIT1    RIT2    NRAS    RRAS

    Find genes that share paralogs with DIRAS2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DIRAS2 (see all 684)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2006098121,2
    --93371806(+) GGATT-/AAAAAA 1 -- ds50010--------
    rs1928963111,2
    --93371888(+) TCTCAC/TCTTAA 1 -- ds50010--------
    rs802745051,2
    C,F--93371890(+) TCACCT/GTAACC 1 -- ds50011Minor allele frequency- G:0.04NA 120
    rs1849664541,2
    --93372077(+) CTAGAC/TCAGCT 1 -- ds50010--------
    rs115396151,2
    C,H--93372226(-) TTATAT/CTTTAT 1 -- ut312Minor allele frequency- C:0.01NS NA 102
    rs1893690931,2
    --93372228(+) AAAATA/GTAATA 1 -- ut310--------
    rs78544691,2
    C,F,A,H--93372229(+) AAATAT/AAATAG 1 -- ut3111Minor allele frequency- A:0.16NS EA NA WA CSA 778
    rs1151160101,2
    C,F--93372349(+) GGGGTA/GTGAAT 1 -- ut311Minor allele frequency- G:0.03WA 118
    rs1810186481,2
    --93372478(+) ATTTTA/TAAAAT 1 -- ut310--------
    rs1397977991,2
    C--93372490(+) TTTAAC/TACATT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DIRAS2 (93372114 - 93405386 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DIRAS2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv893565CNV Gain21882294
    nsv893566CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DIRAS2
    DNA2.0 Custom Variant and Variant Library Synthesis for DIRAS2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607863    OMIM disorders: --


    Find genes that share disorders with DIRAS2           About GenesLikeMe

    Genetic Association Database (GAD): DIRAS2
    Human Genome Epidemiology (HuGE) Navigator: DIRAS2 (1 document)

    Export disorders for DIRAS2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DIRAS2 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with DIRAS2)
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    1. Di-Ras, a distinct subgroup of ras family GTPases with unique biochemical properties. (PubMed id 12194967)1, 2, 3 Kontani K.... Katada T. (J. Biol. Chem. 2002)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. A genome-wide association study identifies protein quantitative trait loci (pQTLs). (PubMed id 18464913)1, 4 Melzer D....Ferrucci L. (PLoS Genet. 2008)
    4. Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. (PubMed id 17903297)1, 4 Seshadri S....Wolf P.A. (BMC Med. Genet. 2007)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    8. DIRAS2 is associated with adult ADHD, related traits, and co-morbid disorders. (PubMed id 21750579)1 Reif A....Lesch K.P. (Neuropsychopharmacology 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54769 HGNC: 19323 AceView: DIRAS2 Ensembl:ENSG00000165023 euGenes: HUgn54769
    ECgene: DIRAS2 H-InvDB: DIRAS2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DIRAS2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DIRAS2 gene:
    Search GeneIP for patents involving DIRAS2

    GeneCards and IP:
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