Free for academic non-profit institutions. Other users need a Commercial license

Aliases for DIEXF Gene

Aliases for DIEXF Gene

  • Digestive Organ Expansion Factor Homolog (Zebrafish) 2 3
  • C1orf107 3 4
  • DEF 3 4
  • Digestive Organ Expansion Factor Homolog 3
  • Digestive-Organ Expansion Factor Homolog 3
  • Chromosome 1 Open Reading Frame 107 2
  • DJ434O14.5 3
  • UTP25 3

External Ids for DIEXF Gene

Previous Symbols for DIEXF Gene

  • C1orf107

Summaries for DIEXF Gene

GeneCards Summary for DIEXF Gene

DIEXF (Digestive Organ Expansion Factor Homolog (Zebrafish)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for DIEXF Gene

  • Regulates the p53 pathway to control the expansion growth of digestive organs.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DIEXF Gene

Genomics for DIEXF Gene

Genomic Location for DIEXF Gene

Start:
209,827,967 bp from pter
End:
209,857,565 bp from pter
Size:
29,599 bases
Orientation:
Plus strand

Genomic View for DIEXF Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DIEXF Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DIEXF Gene

No data available for Regulatory Elements for DIEXF Gene

Proteins for DIEXF Gene

  • Protein details for DIEXF Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q68CQ4-DIEXF_HUMAN
    Recommended name:
    Digestive organ expansion factor homolog
    Protein Accession:
    Q68CQ4
    Secondary Accessions:
    • O75992
    • Q4VY00
    • Q63HL9

    Protein attributes for DIEXF Gene

    Size:
    756 amino acids
    Molecular mass:
    87055 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI95693.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for DIEXF Gene

Proteomics data for DIEXF Gene at MOPED

Post-translational modifications for DIEXF Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DIEXF Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DIEXF Gene

Domains for DIEXF Gene

Protein Domains for DIEXF Gene

UniProtKB/Swiss-Prot:

DIEXF_HUMAN
Family:
  • Belongs to the def family.:
    • Q68CQ4
genes like me logo Genes that share domains with DIEXF: view

No data available for Gene Families for DIEXF Gene

Function for DIEXF Gene

Molecular function for DIEXF Gene

UniProtKB/Swiss-Prot Function: Regulates the p53 pathway to control the expansion growth of digestive organs.

Gene Ontology (GO) - Molecular Function for DIEXF Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0019843 rRNA binding IBA --
GO:0034511 U3 snoRNA binding IBA --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with DIEXF: view

Phenotypes for DIEXF Gene

genes like me logo Genes that share phenotypes with DIEXF: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for DIEXF Gene

Localization for DIEXF Gene

Subcellular locations from UniProtKB/Swiss-Prot for DIEXF Gene

Nucleus. Nucleus, nucleolus.

Gene Ontology (GO) - Cellular Components for DIEXF Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IBA --
GO:0032040 small-subunit processome IBA --
genes like me logo Genes that share ontologies with DIEXF: view

Pathways for DIEXF Gene

SuperPathways for DIEXF Gene

No Data Available

Gene Ontology (GO) - Biological Process for DIEXF Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA --
GO:0007275 multicellular organismal development IEA --
genes like me logo Genes that share ontologies with DIEXF: view

No data available for Pathways by source for DIEXF Gene

Transcripts for DIEXF Gene

Unigene Clusters for DIEXF Gene

Digestive organ expansion factor homolog (zebrafish):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DIEXF Gene

No ASD Table

Relevant External Links for DIEXF Gene

GeneLoc Exon Structure for
DIEXF
ECgene alternative splicing isoforms for
DIEXF

Expression for DIEXF Gene

mRNA expression in normal human tissues for DIEXF Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DIEXF Gene

SOURCE GeneReport for Unigene cluster for DIEXF Gene Hs.194754

genes like me logo Genes that share expressions with DIEXF: view

Orthologs for DIEXF Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DIEXF Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DIEXF 36
  • 99.51 (n)
  • 99.34 (a)
DIEXF 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DIEXF 36
  • 88.62 (n)
  • 92.03 (a)
DIEXF 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DIEXF 36
  • 87.95 (n)
  • 89.38 (a)
DIEXF 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Diexf 36
  • 85.21 (n)
  • 88.34 (a)
Diexf 16
Diexf 37
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DIEXF 37
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DIEXF 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Diexf 36
  • 85.39 (n)
  • 88.98 (a)
chicken
(Gallus gallus)
Aves DIEXF 36
  • 68.4 (n)
  • 70.84 (a)
DIEXF 37
  • 67 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DIEXF 37
  • 68 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.16819 36
tropical clawed frog
(Silurana tropicalis)
Amphibia diexf 36
  • 67.42 (n)
  • 68.8 (a)
Str.11330 36
zebrafish
(Danio rerio)
Actinopterygii diexf 36
  • 59.54 (n)
  • 54.94 (a)
diexf 37
  • 54 (a)
OneToOne
dj434o14.5l 36
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011170 36
  • 51.68 (n)
  • 43.04 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3735 36
  • 51.63 (n)
  • 42.54 (a)
CG3735 37
  • 35 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y41C4A.9 37
  • 31 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ADL209C 36
  • 45.75 (n)
  • 35.2 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP25 36
  • 44.99 (n)
  • 35.6 (a)
UTP25 37
  • 31 (a)
OneToOne
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E08229g 36
  • 46.83 (n)
  • 38.22 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons NOF1 36
  • 49.38 (n)
  • 38.68 (a)
rice
(Oryza sativa)
Liliopsida Os05g0295100 36
  • 48.95 (n)
  • 39.65 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU01022 36
  • 50.49 (n)
  • 41.35 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPCC1827.01c 36
  • 46.16 (n)
  • 38.86 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.1540 36
Species with no ortholog for DIEXF:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DIEXF Gene

ENSEMBL:
Gene Tree for DIEXF (if available)
TreeFam:
Gene Tree for DIEXF (if available)

Paralogs for DIEXF Gene

No data available for Paralogs for DIEXF Gene

Variants for DIEXF Gene

Sequence variations from dbSNP and Humsavar for DIEXF Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs16679 -- 209,834,594(+) GATGA(-/CT)CTAGG intron-variant
rs126280 -- 209,846,479(+) TGGGA(A/G)TTTCT intron-variant
rs581733 -- 209,829,493(+) ttttt(C/T)ttttt intron-variant
rs583814 -- 209,847,626(+) CCCTC(C/T)GGCCA intron-variant
rs585191 -- 209,836,394(+) acatt(A/G)tcaat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DIEXF Gene

Variant ID Type Subtype PubMed ID
nsv873139 CNV Gain 21882294

Relevant External Links for DIEXF Gene

HapMap Linkage Disequilibrium report
DIEXF

Disorders for DIEXF Gene

No disorders were found for DIEXF Gene.

No data available for UniProtKB/Swiss-Prot for DIEXF Gene

Publications for DIEXF Gene

  1. Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish. (PMID: 16322560) Chen J. … Peng J. (Genes Dev. 2005) 2 3 23
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. System-wide changes to SUMO modifications in response to heat shock. (PMID: 19471022) Golebiowski F. … Hay R.T. (Sci Signal 2009) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for DIEXF Gene

Sources for DIEXF Gene

Back to Top

Content