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DIEXF Gene

protein-coding   GIFtS: 42
GCID: GC01P210002

Digestive Organ Expansion Factor Homolog (Zebrafish)

(Previous name: chromosome 1 open reading frame 107)
(Previous symbol: C1orf107)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Digestive Organ Expansion Factor Homolog (Zebrafish)1 2     DJ434O14.52
C1orf1071 2 3     UTP252
DEF2 3     Digestive Organ Expansion Factor Homolog2
Chromosome 1 Open Reading Frame 1071     Digestive-Organ Expansion Factor Homolog2

External Ids:    HGNC: 284401   Entrez Gene: 270422   Ensembl: ENSG000001175977   UniProtKB: Q68CQ43   

Export aliases for DIEXF gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DIEXF Gene:
DIEXF (digestive organ expansion factor homolog (zebrafish)) is a protein-coding gene.

UniProtKB/Swiss-Prot: DIEXF_HUMAN, Q68CQ4
Function: Regulates the p53 pathway to control the expansion growth of digestive organs (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for DIEXF
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for DIEXF

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DIEXF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.2   Ensembl cytogenetic band:  1q32.2   HGNC cytogenetic band: 1q32.2

DIEXF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DIEXF gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P210002:  view genomic region     (about GC identifiers)

Start:
210,001,312 bp from pter      End:
210,030,910 bp from pter
Size:
29,599 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DIEXF_HUMAN, Q68CQ4 (See protein sequence)
Recommended Name: Digestive organ expansion factor homolog  
Size: 756 amino acids; 87055 Da
Sequence caution: Sequence=CAI95693.1; Type=Erroneous gene model prediction;
Secondary accessions: O75992 Q4VY00 Q63HL9

Explore the universe of human proteins at neXtProt for DIEXF: NX_Q68CQ4

Explore proteomics data for DIEXF at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DIEXF Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055203.4  
    ENSEMBL proteins: 
     ENSP00000419005   ENSP00000407345  

    DIEXF Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for DIEXF
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    Novus Biologicals DIEXF Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for DIEXF

     
    Search eBioscience for Proteins for DIEXF 

    DIEXF Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals DIEXF Antibody
    Abcam antibodies for DIEXF
    Cloud-Clone Corp. Antibodies for DIEXF
    Search ThermoFisher Antibodies for DIEXF
    LSBio Antibodies in human, mouse, rat for DIEXF

    DIEXF Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for DIEXF
    Cloud-Clone Corp. CLIAs for DIEXF
    Search eBioscience for ELISAs for DIEXF 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR010678 Digest_organ_expansion_fac-prd
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q68CQ4

    ProtoNet protein and cluster: Q68CQ4

    UniProtKB/Swiss-Prot: DIEXF_HUMAN, Q68CQ4
    Similarity: Belongs to the def family


    Find genes that share domains with DIEXF           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DIEXF_HUMAN, Q68CQ4
    Function: Regulates the p53 pathway to control the expansion growth of digestive organs (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with DIEXF           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for DIEXF:
     Increased gamma-H2AX phosphory  Nuclear pre-40S maturation def  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DIEXF
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DIEXF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DIEXF
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DIEXF

    miRNA
    Products:
        
    miRTarBase miRNAs that target DIEXF:
    hsa-mir-124-3p (MIRT023134), hsa-mir-16-5p (MIRT032008), hsa-mir-186-5p (MIRT044949), hsa-mir-103a-3p (MIRT027143), hsa-mir-196a-5p (MIRT026029), hsa-mir-98-5p (MIRT027794), hsa-mir-151a-3p (MIRT019501)

    Block miRNA regulation of human, mouse, rat DIEXF using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DIEXF (see all 74):
    hsa-miR-3678-3p hsa-miR-4254 hsa-miR-520e hsa-miR-631 hsa-miR-106a hsa-miR-15a hsa-miR-578 hsa-miR-4275
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for DIEXF
    Predesigned siRNA for gene silencing in human, mouse, rat DIEXF

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for DIEXF

    Clone
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    OriGene clones in human, mouse for DIEXF (see all 6)
    OriGene ORF clones in mouse, rat for DIEXF
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DIEXF (NM_014388)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DIEXF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DIEXF

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for DIEXF
    Browse ESI BIO Cell Lines and PureStem Progenitors for DIEXF 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DIEXF


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DIEXF_HUMAN, Q68CQ4: Nucleus (By similarity). Nucleus, nucleolus

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005730nucleolus IEA--

    Find genes that share ontologies with DIEXF           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DIEXF
    Interactions:

        Search GeneGlobe Interaction Network for DIEXF

    Selected Interacting proteins for DIEXF (Q68CQ43) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAGEA11P433643I2D: score=4 
    AURKCQ9UQB93I2D: score=2 
    CAMKK2Q96RR43I2D: score=2 
    CSNK1G2P783683I2D: score=2 
    ENO3P139293I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--

    Find genes that share ontologies with DIEXF           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DIEXF



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DIEXF gene: 
    NM_014388.6  

    Unigene Cluster for DIEXF:

    Digestive organ expansion factor homolog (zebrafish)
    Hs.194754  [show with all ESTs]
    Unigene Representative Sequence: NM_014388
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491415(uc001hhr.2 uc009xcu.2) ENST00000457820
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DIEXF using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DIEXF (see all 74):
    hsa-miR-3678-3p hsa-miR-4254 hsa-miR-520e hsa-miR-631 hsa-miR-106a hsa-miR-15a hsa-miR-578 hsa-miR-4275
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DIEXF
    Predesigned siRNA for gene silencing in human, mouse, rat DIEXF
    Clone
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    OriGene clones in human, mouse for DIEXF (see all 6)
    OriGene ORF clones in mouse, rat for DIEXF
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DIEXF (NM_014388)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DIEXF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DIEXF
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for DIEXF
    OriGene qSTAR qPCR primer pairs in human, mouse for DIEXF
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DIEXF
      QuantiTect SYBR Green Assays in human, mouse, rat DIEXF
      QuantiFast Probe-based Assays in human, mouse, rat DIEXF

    Additional mRNA sequence: 

    AK022766.1 AK096118.1 AK123674.1 AK289613.1 AK295799.1 AK314061.1 BC022964.1 BX648514.1 
    CR749825.1 

    6 DOTS entries:

    DT.445301  DT.101955493  DT.75159964  DT.121375412  DT.92052056  DT.95369694 

    Selected AceView cDNA sequences (see all 146):

    CR598885 BP344955 AA724232 BF593060 BQ000830 AI637490 BM978047 BX402171 
    NM_014388 BM713317 AA043499 BI822921 N58772 BQ006029 AI492447 BE219375 
    AI474271 BQ420891 BP340942 AA962243 AW405014 AI088666 AI982878 AI916582 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DIEXF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    DIEXF Expression
    About this image

    DIEXF Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DIEXF Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.194754
        Custom PCR Arrays for DIEXF
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    QuantiFast Probe-based Assays in human, mouse, rat DIEXF
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DIEXF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DIEXF gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Diexf1 , 5 digestive organ expansion factor homolog (zebrafish)1, 5 85.21(n)1
    88.34(a)1
      1 (97.56 cM)5
    2151931  NM_145415.21  NP_663390.21 
     1931044035 
    chicken
    (Gallus gallus)
    Aves DIEXF1 digestive organ expansion factor homolog (zebrafish) 68.4(n)
    70.84(a)
      421384  NM_001031051.1  NP_001026222.1 
    lizard
    (Anolis carolinensis)
    Reptilia DIEXF6
    digestive organ expansion factor homolog (zebrafis...
    68(a)
    1 ↔ 1
    1(236886951-236904674)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.168192 Xenopus laevis transcribed sequence with weak similarity more 77.76(n)    BX844531.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dj434o14.5l2 novel putative protein similar to YIL091C yeast hypothetical more 75.3(n)   286787  BC058062.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG37351 CG3735 51.63(n)
    42.54(a)
      37803  NM_138007.2  NP_611851.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y41C4A.96
    Protein Y41C4A.9 (Y41C4A.9) mRNA, complete cds
    31(a)
    1 ↔ 1
    III(11710827-11718645) WBGene00012756
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTP251 UTP25 44.99(n)
    35.6(a)
      854717   NP_012175.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons NOF11 NOF1 49.38(n)
    38.68(a)
      838345  NM_101631.1  NP_564032.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g02951001 Os05g0295100 48.95(n)
    39.65(a)
      4338320  NM_001061644.1  NP_001055109.1 


    ENSEMBL Gene Tree for DIEXF (if available)
    TreeFam Gene Tree for DIEXF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DIEXF (see all 740)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs37535151,2
    C,F,H--209999330(-) CTAGAC/TGGTTC 1 -- us2k18Minor allele frequency- T:0.08EA NS NA 1254
    rs173896181,2
    C,F--209999401(+) TGAGAA/GTATAG 1 -- us2k13Minor allele frequency- G:0.01NA 142
    rs170152801,2
    C,F,H--209999413(+) TTTCAT/CAGAAG 1 -- us2k18Minor allele frequency- C:0.01NA NS EA WA 650
    rs1156876831,2
    C,F--209999479(+) TTGGGA/TTATGT 1 -- us2k11Minor allele frequency- T:0.09WA 118
    rs2021788801,2
    --209999552(+) AAAAT-/AATATG 1 -- us2k10--------
    rs1847405821,2
    C--209999583(+) TTTTGG/TTGACC 1 -- us2k10--------
    rs37666161,2
    C,F,A--209999630(-) GCCATT/CTGTCT 1 -- us2k111Minor allele frequency- C:0.36EA NA WA CSA 1674
    rs20380521,2
    C,F,H--209999764(+) TAGTAG/CATGGT 1 -- us2k197Minor allele frequency- C:0.02EA NS MN NA PA EU CA WA 6452
    rs37535131,2
    C,F,H--209999790(-) GAATGC/TGATTC 1 -- us2k1110Minor allele frequency- T:0.09EA NS NA PA EU CA WA 8436
    rs1895082811,2
    --209999798(+) TTCTAA/CTGGTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DIEXF (210001312 - 210030910 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for DIEXF:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv873139CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DIEXF
    DNA2.0 Custom Variant and Variant Library Synthesis for DIEXF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DIEXF gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with DIEXF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish. (PubMed id 16322560)1, 3, 9 Chen J....Peng J. (amp 2005)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    5. Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. (PubMed id 22002106)2 Ahmad Y.... Lamond A.I. (Mol. Cell. Proteomics 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Identification of ubiquitinated proteins from human multiple myeloma U266 cells by proteomics. (PubMed id 22108332)1 Jia H....He Q. (Biomed. Environ. Sci. 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27042 HGNC: 28440 AceView: MGC29875 Ensembl:ENSG00000117597 euGenes: HUgn27042
    ECgene: DIEXF H-InvDB: DIEXF

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DIEXF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DIEXF gene:
    Search GeneIP for patents involving DIEXF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Search Addgene for plasmids for DIEXF
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      eBioscience FlowRNA Probe Sets
           
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