Aliases for DHX8 Gene
External Ids for DHX8 Gene
Previous HGNC Symbols for DHX8 Gene
Previous GeneCards Identifiers for DHX8 Gene
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
GeneCards Summary for DHX8 Gene
DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8) is a Protein Coding gene. Diseases associated with DHX8 include atopic dermatitis and dermatitis. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include RNA binding and ATP-dependent RNA helicase activity. An important paralog of this gene is DHX35.
UniProtKB/Swiss-Prot for DHX8 Gene
Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.