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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DHX57 Gene

protein-coding GIFtS: 53
GCID: GC02M039025

DEAH (Asp-Glu-Ala-Asp/His) Box Polypeptide 57

Search for DHX57
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
DEAH (Asp-Glu-Ala-Asp/His) Box Polypeptide 57¹ ²		Putative ATP-Dependent RNA Helicase DHX57²
DEAH Box Protein 57² ³		EC 3.6.4.13³
DDX57²		EC 3.6.1⁸
DEAH-Box RNA/DNA Helicase AAM73547²

External Ids:	HGNC: 20086¹	Entrez Gene: 90957²	Ensembl: ENSG00000163214⁷	UniProtKB: Q6P158³

Export aliases for DHX57 gene to outside databases

Previous GC identifers: GC02M038982 GC02M038999 GC02M038936 GC02M038878 GC02M038763

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DHX57 Gene:

DHX57 (DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57) is a protein-coding gene. GO annotations related to this gene include ATP-dependent helicase activity and nucleic acid binding. An important paralog of this gene is DHX29.

UniProtKB/Swiss-Prot: DHX57_HUMAN, Q6P158

Function: Probable ATP-binding RNA helicase

Gene Wiki entry for DHX57 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NT_022184.15 NC_018913.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DHX57 gene promoter:
E2F-3a E2F-4 C/EBPbeta E2F-5 E2F-2 CUTL1 Evi-1 Pax-3 E2F-1 E2F
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DHX57 promoter sequence

Search SABiosciences Chromatin IP Primers for DHX57

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHX57

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p22.1 Ensembl cytogenetic band: 2p22.1 HGNC cytogenetic band: 2p22.3

DHX57 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHX57 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M039025: view genomic region (about GC identifiers)

Start:	39,024,871 bp from pter	End:	39,103,075 bp from pter
Size:	78,205 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DHX57_HUMAN, Q6P158 (See protein sequence)

Recommended Name: Putative ATP-dependent RNA helicase DHX57

Size: 1386 amino acids; 155604 Da

Sequence caution: Sequence=AAM73547.1; Type=Erroneous initiation; Sequence=AAY24256.1; Type=Erroneous gene model

prediction;

Secondary accessions: A2RRC7 Q53SI4 Q6P9G1 Q7Z6H3 Q8NG17 Q96M33

Alternative splicing: 3 isoforms: Q6P158-1 Q6P158-2 Q6P158-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DHX57: NX_Q6P158

Explore proteomics data for DHX57 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q6P158

4/7 DME Specific Peptides for DHX57 (Q6P158) (see all 7)

TNIAETS

AETSITI

VDEVHER

VILMSAT

DHX57 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_945314.1

ENSEMBL proteins:

ENSP00000295373 ENSP00000397841 ENSP00000405111 ENSP00000387404 ENSP00000400702

Human Recombinant Protein Products for DHX57:

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Assay Products for DHX57:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for DHX57
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	Cloud-Clone Corp. ELISAs for DHX57 Cloud-Clone Corp. CLIAs for DHX57

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

DHX: DEAH-boxes

5/11 InterPro protein domains (see all 11):

IPR000571 Znf_CCCH

IPR011545 DNA/RNA_helicase_DEAD/DEAH_N

IPR002464 DNA/RNA_helicase_DEAH_CS

IPR009060 UBA-like

IPR006575 RWD-domain

Graphical View of Domain Structure for InterPro Entry Q6P158

ProtoNet protein and cluster: Q6P158

4 Blocks protein domains:

IPB000571 Zn-finger

IPB002464 ATP-dependent helicase

IPB006575 RWD

IPB007502 Helicase-associated region

UniProtKB/Swiss-Prot: DHX57_HUMAN, Q6P158

Similarity: Belongs to the DEAD box helicase family. DEAH subfamily

Similarity: Contains 1 C3H1-type zinc finger

Similarity: Contains 1 helicase ATP-binding domain

Similarity: Contains 1 helicase C-terminal domain

Similarity: Contains 1 UBA domain

DHX57 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: DHX57_HUMAN, Q6P158

Function: Probable ATP-binding RNA helicase

Catalytic activity: ATP + H(2)O = ADP + phosphate

Enzyme Numbers (IUBMB): EC 3.6.1² EC 3.6.4.13¹

Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003676	nucleic acid binding	IEA	--
GO:0004386	helicase activity	--	--
GO:0005515	protein binding	--	--
GO:0005524	ATP binding	IEA	--
GO:0008026	ATP-dependent helicase activity	IEA	--

DHX57 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for DHX57

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DHX57

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DHX57

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DHX57

miRNA Products:		miRTarBase miRNAs that target DHX57: hsa-let-7b (MIRT001639)

		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DHX57
		8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate DHX57 (see all 18):
		hsa-miR-181c hsa-let-7d hsa-let-7c hsa-miR-218 hsa-let-7g hsa-miR-320e hsa-let-7a hsa-miR-3662

		SwitchGear 3'UTR luciferase reporter plasmid: DHX57 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DHX57
		Search LifeMap BioReagents cell lines for DHX57

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX57

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DHX57

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5/103 Interacting proteins for DHX57 (Q6P158^{2, 3} ENSP00000295373⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 103)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DDX21	Q9NR30², ENSP00000346120⁴	MINT-8395092 STRING: ENSP00000346120
DDX56	Q9NY93³, ENSP00000258772⁴	I2D: score=2 STRING: ENSP00000258772
LYAR	Q9NX58³, ENSP00000345917⁴	I2D: score=2 STRING: ENSP00000345917
GABARAP	O95166³	I2D: score=1
CAD	P27708²	MINT-8395092

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DHX57

Search CenterWatch for drugs/clinical trials and news about DHX57

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DHX57 gene:

NM_198963.1

Unigene Cluster for DHX57:

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

Hs.468226 [show with all ESTs]

Unigene Representative Sequence: BC153875

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000295373(uc002rre.3 uc002rrf.3) ENST00000452978 ENST00000460193(uc002rrd.4)

ENST00000457308 ENST00000477981 ENST00000497514 ENST00000442331 ENST00000474104(uc002rrg.3)

ENST00000492042 ENST00000479345 ENST00000417233

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DHX57
		8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate DHX57 (see all 18):
		hsa-miR-181c hsa-let-7d hsa-let-7c hsa-miR-218 hsa-let-7g hsa-miR-320e hsa-let-7a hsa-miR-3662

		SwitchGear 3'UTR luciferase reporter plasmid: DHX57 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for DHX57
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DHX57

Clone Products:		OriGene clones in human, mouse for DHX57 (see all 5) OriGene ORF clones in mouse, rat for DHX57 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DHX57
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHX57

Additional mRNA sequence:

AB209249.1 AF070590.1 AF283512.1 AK057423.1 AK296739.1 AK307514.1 BC012454.1 BC033636.1

BC039270.1 BC053623.1 BC060778.1 BC065278.1 BC131534.1 BC153875.1

10 DOTS entries:

DT.441867 DT.303178 DT.442758 DT.101975844 DT.40117842 DT.110310 DT.92418889 DT.120931050

DT.120931024 DT.92418888

24/110 AceView cDNA sequences (see all 110):

BF970974 AA278968 AA431613 NM_198963 AI204143 BM352293 BQ719095 BF739883

BX102332 BC065278 AF070590 NM_145646 BU189567 AA343694 BC053623 BE219229

AI125363 AI203420 AA099678 CR620209 BU183594 BM998629 Z40862 AA255869

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for DHX57 (see all 7) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4	^	5a	·	5b	^	6a	·	6b	^	7a	·	7b	^	8	^	9a	·	9b	^	10a	·	10b	·	10c	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16	^	17	^
SP1:																									-												-
SP2:																									-						-						-
SP3:																									-						-
SP4:
SP5:					-		-

ExUns:	18	^	19	^	20	^	21	^	22	^	23	^	24	^	25	^	26a	·	26b
SP1:
SP2:
SP3:													-
SP4:
SP5:

ECgene alternative splicing isoforms for DHX57

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DHX57 expression in normal human tissues (normalized intensities) DHX57 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: AAGAGAAATA

About this image

DHX57 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/4 selected tissues (see all 4) fully expand


Brain (Nervous System) fully expand to see all 13 entries
Thalamus
Septum

Testis (Reproductive System)
sperm

Ovary (Reproductive System)
oocyte

Spinal Cord (Nervous System)
Dorsal Horn

See DHX57 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DHX57

SOURCE GeneReport for Unigene cluster: Hs.468226

SABiosciences Custom PCR Arrays for DHX57

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHX57

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX57

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for DHX57 gene from 7/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Dhx57^{1 , 5}	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57^{1, 5}	84.43(n)¹ 87.15(a)¹		17 (50.63 cM)⁵ 106794¹ NM_001163759.1¹ NP_001157231.1¹ 80238304⁵
chicken (Gallus gallus)	Aves	DHX57¹	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57	73.15(n) 76.21(a)		426560 XM_424198.3 XP_424198.3
lizard (Anolis carolinensis)	Reptilia	DHX57⁶	Uncharacterized protein	71(a)	1 ↔ 1	1(253984454-254026256)
African clawed frog (Xenopus laevis)	Amphibia	48026484²	--	70.57(n)		48026484
zebrafish (Danio rerio)	Actinopterygii	dhx57¹	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57	61.49(n) 62.1(a)		555250 XM_001921028.1 XP_001921063.1
fruit fly (Drosophila melanogaster)	Insecta	CG1582¹	CG1582	49.49(n) 44.26(a)		32021 NM_132435.1 NP_572663.1
rice (Oryza sativa)	Liliopsida	Os.2502²	Oryza sativa (japonica cultivar-group) putative ATP-dependent more	76.41(n)		NM_196962.1

ENSEMBL Gene Tree for DHX57 (if available)
TreeFam Gene Tree for DHX57 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DHX57 gene

DHX29² DHX30² DHX36² TDRD9² YTHDC2² DHX9²

4 SIMAP similar genes for DHX57 using alignment to 7 protein entries: DHX57_HUMAN (see all proteins):

DHX29 DHX36 HIG-1 DKFZp762F2011

DHX57 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs192100183^1,2		--	39024501(+)	`TTTCTA/GCTCAG`	1	--	int¹		0	--	--	--	--
rs76091425^1,2	C,F	--	39024722(+)	`CCTTCG/AGTGAT`	1	--	int¹		1		WA	118
rs79224990^1,2	C,F	--	39024784(+)	`TATGAC/TGACAT`	1	--	int¹		2		WA	120
rs1063637^1,2	C	--	39025017(-)	`GACTGA/CGAGAA`	1	--	ut3¹		1		NA	2
rs1063636^1,2	C	--	39025043(-)	`TTTTTC/TTTTTC`	1	--	ut3¹		0	--	--	--	--
rs34252629^1,2	C	--	39025044(+)	`AAAAG-/AAAAAA`	1	--	ut3¹		0	--	--	--	--
rs138987065^1,2	C	--	39025352(+)	`CCCAAC/TAGGTC`	1	--	ut3¹		0	--	--	--	--
rs184277708^1,2	C	--	39025397(+)	`CAGGTA/GAGCTA`	1	--	ut3¹		0	--	--	--	--
rs199851623^1,2	C	--	39025429(+)	`CTCTCA/TAAGAC`	1	--	ut3¹		0	--	--	--	--
rs201336111^1,2		--	39025495(+)	`CGAGGA/GCACGT`	2	C	syn¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for DHX57 (39024871 - 39103075 bp)

Structural Variations
Database of Genomic Variants (DGV) 8 variations for DHX57: About this table

Variant ID	Type	Subtype	PubMed ID
esv1777011	CNV	Deletion	17803354
esv2719952	CNV	Deletion	23290073
esv1005417	CNV	Deletion	20482838
esv4781	CNV	Deletion	18987735
esv268479	CNV	Insertion	20981092
esv6905	CNV	Loss	19470904
nsv9646	CNV	Loss	18304495
nsv2692	CNV	Loss	18451855

SABiosciences Cancer Mutation PCR Assays

SeqTarget long-range PCR primers for resequencing DHX57

DNA2.0 Custom Variant and Variant Library Synthesis for DHX57

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DHX57 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with DHX57)

Utopia: connect your pdf to the dynamic
world of online information

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)^{1, 2} Hillier L.W....Wilson R.K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)¹ Woods N.T....Monteiro A.N. (2012)
Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C....Cristea I.M. (2012)
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)¹ Comuzzie A.G....Butte N.F. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 90957	HGNC: 20086	AceView: DHX57	Ensembl:ENSG00000163214	euGenes: HUgn90957
ECgene: DHX57	H-InvDB: DHX57

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DHX57	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DHX57 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DHX57 gene:
Search GeneIP for patents involving DHX57

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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DHX57 Gene

DEAH (Asp-Glu-Ala-Asp/His) Box Polypeptide 57

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DHX57 Gene

DEAH (Asp-Glu-Ala-Asp/His) Box Polypeptide 57

Aliasesfor DHX57 gene

Summariesfor DHX57 gene

Genomic Viewsfor DHX57 gene

Proteinsfor DHX57 gene

Protein Domains /Familiesfor DHX57 gene

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for DHX57 gene

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for DHX57 gene

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Families
for DHX57 gene

Function
for DHX57 gene

Pathways & Interactions
for DHX57 gene

Drugs & Compounds
for DHX57 gene

Transcripts
for DHX57 gene

Expression
for DHX57 gene

Orthologs
for DHX57 gene

Paralogs
for DHX57 gene

Genomic Variants
for DHX57 gene

Disorders / Diseases
for DHX57 gene

Publications
for DHX57 gene

Intellectual Property
for DHX57 gene

Products
for DHX57 gene