Aliases for DHX38 Gene
External Ids for DHX38 Gene
Previous HGNC Symbols for DHX38 Gene
Previous GeneCards Identifiers for DHX38 Gene
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008]
GeneCards Summary for DHX38 Gene
DHX38 (DEAH-Box Helicase 38) is a Protein Coding gene. Diseases associated with DHX38 include Retinitis Pigmentosa and Mental Retardation-Hypotonic Facies Syndrome, X-Linked. Among its related pathways are Transport of Mature Transcript to Cytoplasm and mRNA Splicing - Major Pathway. GO annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is DHX8.
UniProtKB/Swiss-Prot for DHX38 Gene
Probable ATP-binding RNA helicase involved in pre-mRNA splicing.