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DHX37 Gene

protein-coding   GIFtS: 51
GCID: GC12M125431

DEAH (Asp-Glu-Ala-His) Box Polypeptide 37

(Previous name: DEAD/DEAH box helicase DDX37)
(Previous symbol: DDX37)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DEAH (Asp-Glu-Ala-His) Box Polypeptide 371 2     Probable ATP-Dependent RNA Helicase DHX372
DDX371 2 3     EC 3.6.4.133
DEAD/DEAH Box Helicase DDX371 2     KIAA15173
DEAH Box Protein 372 3     EC 3.6.18
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 372     

External Ids:    HGNC: 172101   Entrez Gene: 576472   Ensembl: ENSG000001509907   UniProtKB: Q8IY373   

Export aliases for DHX37 gene to outside databases

Previous GC identifers: GC12M125155 GC12M123784 GC12M123956 GC12M123997 GC12M122392


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DHX37 Gene:
This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp
(DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of
RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and
spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be
involved in embryogenesis, spermatogenesis, and cellular growth and division. (provided by RefSeq, Jul 2008)

GeneCards Summary for DHX37 Gene:
DHX37 (DEAH (Asp-Glu-Ala-His) box polypeptide 37) is a protein-coding gene. GO annotations related to this gene include ATP-dependent helicase activity and nucleic acid binding.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DHX37 gene promoter:
         Elk-1   NRSF form 1   NRSF form 2   AP-2gamma   c-Ets-1   HNF-4alpha1   NRF-2   HSF2   STAT3   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDHX37 promoter sequence
   Search Chromatin IP Primers for DHX37

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DHX37


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

DHX37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHX37 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M125431:  view genomic region     (about GC identifiers)

Start:
125,431,370 bp from pter      End:
125,473,668 bp from pter
Size:
42,299 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DHX37_HUMAN, Q8IY37 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DHX37  
Size: 1157 amino acids; 129545 Da
Secondary accessions: Q9BUI7 Q9P211

Explore the universe of human proteins at neXtProt for DHX37: NX_Q8IY37

Explore proteomics data for DHX37 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys118, Lys786
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for DHX37 (Q8IY37)
     TGSGKTTQ  PQFLYEAG 


    See DHX37 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_116045.2  
    ENSEMBL proteins: 
     ENSP00000439009   ENSP00000443661   ENSP00000311135  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DHX: DEAH-boxes

    Selected InterPro protein domains (see all 6):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR007502 Helicase-assoc_dom
     IPR011709 DUF1605
     IPR027417 P-loop_NTPase
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry Q8IY37

    ProtoNet protein and cluster: Q8IY37

    2 Blocks protein domains:
    IPB002464 ATP-dependent helicase
    IPB007502 Helicase-associated region


    UniProtKB/Swiss-Prot: DHX37_HUMAN, Q8IY37
    Similarity: Belongs to the DEAD box helicase family. DEAH subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    Find genes that share domains with DHX37           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DHX37_HUMAN, Q8IY37
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--
         
    Find genes that share ontologies with DHX37           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for DHX37:
     Nucleolar pre-40S maturation d 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DHX37
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DHX37

    miRNA
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    miRTarBase miRNAs that target DHX37:
    hsa-mir-193b-3p (MIRT041293), hsa-mir-16-5p (MIRT031884), hsa-mir-15b-5p (MIRT046511)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DHX37
    Interactions:

        Search GeneGlobe Interaction Network for DHX37

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DHX37 (Q8IY373 ENSP000003111354) via UniProtKB, MINT, STRING, and/or I2D (see all 199)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----

    Find genes that share ontologies with DHX37           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DHX37



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DHX37 gene: 
    NM_032656.3  

    Unigene Cluster for DHX37:

    DEAH (Asp-Glu-Ala-His) box polypeptide 37
    Hs.107382  [show with all ESTs]
    Unigene Representative Sequence: NM_032656
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000542400 ENST00000539298(uc001ugy.3) ENST00000544745(uc001ugz.1)
    ENST00000507267 ENST00000543962 ENST00000308736
    miRNA
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    Block miRNA regulation of human, mouse, rat DHX37 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate DHX37
    SwitchGear 3'UTR luciferase reporter plasmidDHX37 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DHX37
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      QuantiFast Probe-based Assays in human, mouse, rat DHX37

    Additional mRNA sequence: 

    AB040950.1 BC002575.2 BC004463.1 BC009913.2 BC037964.1 BC071824.1 

    6 DOTS entries:

    DT.411547  DT.92432887  DT.100751856  DT.95373122  DT.97775795  DT.100710298 

    Selected AceView cDNA sequences (see all 180):

    NM_032656 BC004463 AI400954 BU736777 AA760826 BQ059476 AW474641 AI697690 
    AI469528 BE408225 BM704718 BC009913 BQ065222 BU538829 BU633416 AK123968 
    BE267101 AW194022 BQ215421 BQ919256 BM694188 BM727740 BU539352 BE019472 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for DHX37    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22a · 22b ^ 23 ^
    SP1:                                                                          -                                                                 -               
    SP2:                                                                          -                                                                 -               
    SP3:                                                                                                                                                            
    SP4:                                                                                                        -     -     -                                       
    SP5:                                                                                                                                                            

    ExUns: 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for DHX37

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DHX37 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGAGGGCAC
    DHX37 Expression
    About this image

    DHX37 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DHX37 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.107382
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX37

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DHX37 gene from Selected species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dhx371 , 5 DEAH (Asp-Glu-Ala-His) box polypeptide 371, 5 81.38(n)1
    84.5(a)1
      5 (64.20 cM)5
    2081441  NM_203319.11  NP_976064.11 
     1254144065 
    chicken
    (Gallus gallus)
    Aves DHX371 DEAH (Asp-Glu-Ala-His) box polypeptide 37 68.83(n)
    72.61(a)
      416813  XM_415104.4  XP_415104.3 
    lizard
    (Anolis carolinensis)
    Reptilia DHX376
    DEAH (Asp-Glu-Ala-His) box polypeptide 37
    69(a)
    1 ↔ 1
    LGb(1313349-1328807)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.69452 Xenopus laevis transcribed sequence with weak similarity more 73.83(n)    BQ735410.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd11d062 Transcribed sequence with weak similarity to protein more 70.55(n)    BQ264148.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta kz1 kurz 55.99(n)
    51.82(a)
      31205  NM_057243.4  NP_476591.1 
    worm
    (Caenorhabditis elegans)
    Secernentea rha-21 rha-2 49.13(n)
    47.29(a)
      176207  NM_066494.1  NP_498895.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ECM16(YMR128W)4 Essential DEAH-box ATP-dependent RNA helicase specific more   --   13(523696-527499) 855158  NP_013847.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons FAS41 FAS4 47.91(n)
    43.51(a)
      840232  NM_103064.3  NP_174605.1 
    rice
    (Oryza sativa)
    Liliopsida Os.252002 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 71.94(n)    AK121498.1 


    ENSEMBL Gene Tree for DHX37 (if available)
    TreeFam Gene Tree for DHX37 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DHX37 (see all 1495)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs108467811,2
    C,F,A,H--125430885(+) ATGAGG/CAGGCA 1 -- ds500114Minor allele frequency- C:0.22NS EA NA WA CSA 789
    rs1380191281,2
    C--125431015(+) TACTTG/TCGAGT 1 -- ds50010--------
    rs743550711,2
    C,F--125431076(+) TCACCG/AGGCGG 1 -- ds50011Minor allele frequency- A:0.04WA 118
    rs1809613691,2
    --125431079(+) CCGGGC/TGGGTC 1 -- ds50010--------
    rs43607871,2
    C,F,H--125431128(+) CTGCCT/CTGGGC 1 -- ds500120Minor allele frequency- C:0.17NS EA NA WA CSA 2346
    rs569507111,2
    F--125431289(+) GGAAGG/ACAGGT 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs583590901,2
    F--125431290(+) GAAGGC/AAGGTC 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1849856441,2
    --125431417(+) AAGCCA/GCAGAA 1 -- ut310--------
    rs1901836231,2
    --125431436(+) AGGAGC/TAGAAT 1 -- ut310--------
    rs1421148151,2
    --125431535(+) CCTGGA/GGTGCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DHX37 (125431370 - 125473668 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for DHX37:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1114476CNV Deletion17803354
    esv2746554CNV Deletion23290073
    esv2746553CNV Deletion23290073
    nsv520994CNV Gain+Loss19592680

    Human Gene Mutation Database (HGMD): DHX37
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DHX37
    DNA2.0 Custom Variant and Variant Library Synthesis for DHX37

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with DHX37           About GenesLikeMe


    Export disorders for DHX37 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DHX37 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with DHX37)
        Utopia: connect your pdf to the dynamic
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    1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Development and application of a DNA microarray-based yeast two-hybrid system. (PubMed id 23275563)1 Suter B....Wanker E.E. (Nucleic Acids Res. 2013)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    6. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PubMed id 22751105)1 Chu L....Tomasson M.H. (J. Clin. Invest. 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    9. The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (PLoS ONE 2010)
    10. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M....Figeys D. (Mol. Syst. Biol. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
    PubMed
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57647 HGNC: 17210 AceView: DHX37 Ensembl:ENSG00000150990 euGenes: HUgn57647
    ECgene: DHX37 H-InvDB: DHX37

    (According to HUGE)
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    HUGE: KIAA1517

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DHX37 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DHX37 gene:
    Search GeneIP for patents involving DHX37

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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