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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DHX37 Gene

protein-coding   GIFtS: 50
GCID: GC12M125431

DEAH (Asp-Glu-Ala-His) box polypeptide 37

(Previous name: DEAD/DEAH box helicase DDX37 )
(Previous symbol: DDX37)
 Explore 1 disease affiliated with
DHX37 via our new
 Human Malady Compendium 
Biological research products
for DHX37
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
DEAH (Asp-Glu-Ala-His) Box Polypeptide 371 2     MGC43221
DDX371 2 3     DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 372
DEAD/DEAH Box Helicase DDX371 2     Probable ATP-Dependent RNA Helicase DHX372
KIAA15171 3     EC 3.6.4.133
DEAH Box Protein 372 3     EC 3.6.18
MGC26951     

External Ids:    HGNC: 172101   Entrez Gene: 576472   Ensembl: ENSG000001509907   UniProtKB: Q8IY373   

Export aliases for DHX37 gene to outside databases

Previous GC identifers: GC12M125155 GC12M123784 GC12M123956 GC12M123997 GC12M122392


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DHX37:
This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD),
are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA
secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome
assembly. Based on their distribution patterns, some members of this family are believed to be involved in
embryogenesis, spermatogenesis, and cellular growth and division. (provided by RefSeq, Jul 2008)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_009755.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DHX37 gene promoter:
         Elk-1   NRSF form 1   NRSF form 2   AP-2gamma   c-Ets-1   HNF-4alpha1   NRF-2   HSF2   STAT3   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDHX37 promoter sequence
   Search SABiosciences Chromatin IP Primers for DHX37

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHX37


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

DHX37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHX37 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M125431:  view genomic region     (about GC identifiers)

Start:
125,431,371 bp from pter      End:
125,473,668 bp from pter
Size:
42,298 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DHX37_HUMAN, Q8IY37 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DHX37  
Size: 1157 amino acids; 129545 Da
Secondary accessions: Q9BUI7 Q9P211

Explore the universe of human proteins at neXtProt for DHX37: NX_Q8IY37

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8IY37

  • 2 DME Specific Peptides for DHX37 (Q8IY37)
     TGSGKTTQ  PQFLYEAG 

    DHX37 Protein expression data from MOPED and PaxDb:    About this image 
    DHX37 Protein Expression
    REFSEQ proteins: NP_116045.2  
    ENSEMBL proteins: 
     ENSP00000439009   ENSP00000443661   ENSP00000311135  

    Human Recombinant Protein Products for DHX37: 
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    Uscn Proteins for DHX37


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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DHX37 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR007502 Helicase-assoc_dom
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR011709 DUF1605
     IPR014001 Helicase_ATP-bd
     IPR001650 Helicase_C

    Graphical View of Domain Structure for InterPro Entry Q8IY37

    ProtoNet protein and cluster: Q8IY37

    2 Blocks protein families:
    IPB002464 ATP-dependent helicase
    IPB007502 Helicase-associated region


    UniProtKB/Swiss-Prot: DHX37_HUMAN, Q8IY37
    Similarity: Belongs to the DEAD box helicase family. DEAH subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DHX37_HUMAN, Q8IY37
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--
         
    DHX37 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DHX37:
     Nucleolar pre-40S maturation d 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DHX37 

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidDHX37 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DHX37 (see all 7)
    OriGene shRNA RFP: DHX37
    OriGene siRNA: DHX37
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX37


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DHX37

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/118 Interacting proteins for DHX37 (Q8IY373 ENSP000003111354) via UniProtKB, MINT, STRING, and/or I2D (see all 118)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DHX37
    Search CenterWatch for drugs/clinical trials and news about DHX37 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DHX37 gene: 
    NM_032656.3  

    Unigene Cluster for DHX37:

    DEAH (Asp-Glu-Ala-His) box polypeptide 37
    Hs.107382  [show with all ESTs]
    Unigene Representative Sequence: NM_032656
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000542400 ENST00000539298(uc001ugy.3) ENST00000544745(uc001ugz.1)
    ENST00000507267 ENST00000543962 ENST00000308736

    miRNA
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    Inhib. RNA
    Products:
         
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DHX37 (see all 7)
    OriGene shRNA RFP: DHX37
    OriGene siRNA: DHX37
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DHX37
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHX37

    Additional cDNA sequence: 

    AB040950.1 BC002575.2 BC004463.1 BC009913.2 BC037964.1 BC071824.1 

    6 DOTS entries:

    DT.411547  DT.92432887  DT.100751856  DT.95373122  DT.97775795  DT.100710298 

    24/180 AceView cDNA sequences (see all 180):

    BC004463 BQ065222 BC009913 BQ059476 BG818886 BU736777 AI400954 BM704718 
    BE408225 AI469528 BQ062197 AW770378 AI697690 BQ919256 BM694188 BU539352 
    BM727740 AK123968 BU633416 AW474641 AA760826 BF915047 NM_032656 BQ215421 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for DHX37    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22a · 22b ^ 23 ^
    SP1:                                                                          -                                                                 -               
    SP2:                                                                          -                                                                 -               
    SP3:                                                                                                                                                            
    SP4:                                                                                                        -     -     -                                       
    SP5:                                                                                                                                                            

    ExUns: 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for DHX37

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DHX37 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGAGGGCAC
    DHX37 Expression
    About this image
    See DHX37 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DHX37

    SOURCE GeneReport for Unigene cluster: Hs.107382
        SABiosciences Custom PCR Arrays for DHX37

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DHX37 gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves DHX371 DEAH (Asp-Glu-Ala-His) box polypeptide 37 69.71(n)
    73.37(a)
      416813  XM_415104.3  XP_415104.2 
    lizard
    (Anolis carolinensis)
    Reptilia DHX376
    --
    69(a)
    1 ↔ 1
    LGb(1313480-1328807)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.69452 Xenopus laevis transcribed sequence with weak similarity more 73.83(n)    BQ735410.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd11d062 Transcribed sequence with weak similarity to protein more 70.55(n)    BQ264148.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta kz1 kurz 53.89(n)
    48.52(a)
      31205  NM_057243.3  NP_476591.1 
    worm
    (Caenorhabditis elegans)
    Secernentea rha-21 Protein RHA-2 47.92(n)
    44.22(a)
      176207  NM_066494.1  NP_498895.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ECM16(YMR128W)4
    ECM161
    Essential DEAH-box ATP-dependent RNA helicase specific more4
    Ecm16p1
    48.78(n)1
    45.97(a)1
      13(523696-527499)4
    8551581, 4  NP_013847.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons FAS41 putative RNA helicase 46.48(n)
    40.68(a)
      840232  NM_103064.3  NP_174605.1 
    rice
    (Oryza sativa)
    Liliopsida Os.252002 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 71.94(n)    AK121498.1 


    ENSEMBL Gene Tree for DHX37 (if available)
    TreeFam Gene Tree for DHX37 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1165 NCBI SNPs in DHX37 are shown (see all 1165    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2008378011,2
    C--122422648(-) TTTTCC/TTTTTT 1 -- int10--------
    rs108467811,2
    C,F,A,H--125430885(+) ATGAGG/CAGGCA 1 -- ds500114Minor allele frequency- C:0.22NS EA NA WA CSA 789
    rs1380191281,2
    --125431015(+) TACTTG/TCGAGT 1 -- ds50010--------
    rs743550711,2
    F--125431076(+) TCACCG/AGGCGG 1 -- ds50011Minor allele frequency- A:0.04WA 118
    rs1809613691,2
    --125431079(+) CCGGGC/TGGGTC 1 -- ds50010--------
    rs43607871,2
    C,F,H--125431128(+) CTGCCT/CTGGGC 1 -- ds500120Minor allele frequency- C:0.17NS EA NA WA CSA 2346
    rs569507111,2
    F--125431289(+) GGAAGG/ACAGGT 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs583590901,2
    F--125431290(+) GAAGGC/AAGGTC 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1849856441,2
    --125431417(+) AAGCCA/GCAGAA 1 -- ut310--------
    rs1901836231,2
    --125431436(+) AGGAGC/TAGAAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DHX37 (125431371 - 125473668 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for DHX37
         2 Indels: 39940 24890
    Human Gene Mutation Database (HGMD): DHX37

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DHX37
    DNA2.0 Custom Variant and Variant Library Synthesis for DHX37

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DHX37 for disorders           About GeneDecksing

    1 disease for DHX37:    About MalaCards
    malaria


    Export disorders for DHX37 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DHX37 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with DHX37)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    4. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (2010)
    7. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
    8. Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. (PubMed id 12421765)1 Nakayama M....Ohara O. (2002)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57647 HGNC: 17210 AceView: DHX37 Ensembl:ENSG00000150990 euGenes: HUgn57647
    ECgene: DHX37 H-InvDB: DHX37

    (According to HUGE)
    About This Section
    HUGE: KIAA1517

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DHX37 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DHX37 gene:
    Search GeneIP for patents involving DHX37

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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