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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DHX35 Gene

protein-coding GIFtS: 47
GCID: GC20P037590

DEAH (Asp-Glu-Ala-His) box polypeptide 35

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 35 )
(Previous symbols: C20orf15, DDX35)

Search for DHX35
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
DEAH (Asp-Glu-Ala-His) Box Polypeptide 35¹ ²		FLJ22759¹
C20orf15¹ ² ³		DEAH-Box Protein 35²
DDX35¹ ² ³		Probable ATP-Dependent RNA Helicase DHX35²
KAIA0875¹ ²		EC 3.6.4.13³
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 35¹ ²		EC 3.6.1⁸
DEAH Box Protein 35² ³

External Ids:	HGNC: 15861¹	Entrez Gene: 60625²	Ensembl: ENSG00000101452⁷	UniProtKB: Q9H5Z1³

ORGUL members:
	NONCODE:n409520

Export aliases for DHX35 gene to outside databases

Previous GC identifers: GC20P038229 GC20P038276 GC20P037024 GC20P034328

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DHX35:

DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are

implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation

initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution

patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis,

and cellular growth and division. The function of this gene product which is a member of this family, has not been

determined. Alternatively spliced transcript variants have been found for this gene. (provided by RefSeq, Jun 2010)

UniProtKB/Swiss-Prot: DHX35_HUMAN, Q9H5Z1

Function: May be involved in pre-mRNA splicing

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011362.10

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DHX35 gene promoter:
GR STAT5B USF1 GATA-3 C/EBPalpha USF-1 FOXJ2 (long isoform) Cart-1 GR-alpha FOXJ2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DHX35 promoter sequence

Search SABiosciences Chromatin IP Primers for DHX35

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHX35

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.22-q12 Ensembl cytogenetic band: 20q11.23 HGNC cytogenetic band: 20q11.22-q12

DHX35 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHX35 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P037590: view genomic region (about GC identifiers)

Start:	37,590,942 bp from pter	End:	37,668,366 bp from pter
Size:	77,425 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DHX35_HUMAN, Q9H5Z1 (See protein sequence)

Recommended Name: Probable ATP-dependent RNA helicase DHX35

Size: 703 amino acids; 78910 Da

Subunit: Identified in the spliceosome C complex

Sequence caution: Sequence=BAB15166.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Secondary accessions: A2RTX3 Q5THR0 Q9H4H7 Q9H6T6

Explore the universe of human proteins at neXtProt for DHX35: NX_Q9H5Z1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9H5Z1

4/6 DME Specific Peptides for DHX35 (Q9H5Z1) (see all 6)

FLTGQEE

AETSITI

CYRLYTE

LDEAHERT

DHX35 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001177738.1 NP_068750.2

ENSEMBL proteins:

ENSP00000362422 ENSP00000252011 ENSP00000432603 ENSP00000414630 ENSP00000397997

ENSP00000362420

Human Recombinant Protein Products:

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	Novus Biologicals DHX35 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for DHX35

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0071013	catalytic step 2 spliceosome	IDA	11991638

DHX35 for ontologies About GeneDecksing

DHX35 Antibody Products:

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	Uscn ELISAs and CLIAs for DHX35

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DHX35 for domains About GeneDecksing

5 InterPro domains/families:

IPR007502 Helicase-assoc_dom

IPR011709 DUF1605

IPR002464 DNA/RNA_helicase_DEAH_CS

IPR014001 Helicase_ATP-bd

IPR001650 Helicase_C

Graphical View of Domain Structure for InterPro Entry Q9H5Z1

ProtoNet protein and cluster: Q9H5Z1

2 Blocks protein families:

IPB002464 ATP-dependent helicase

IPB007502 Helicase-associated region

UniProtKB/Swiss-Prot: DHX35_HUMAN, Q9H5Z1

Similarity: Belongs to the DEAD box helicase family. DEAH subfamily

Similarity: Contains 1 helicase ATP-binding domain

Similarity: Contains 1 helicase C-terminal domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: DHX35_HUMAN, Q9H5Z1

Function: May be involved in pre-mRNA splicing

Catalytic activity: ATP + H(2)O = ADP + phosphate

Enzyme Numbers (IUBMB): EC 3.6.1² EC 3.6.4.13¹

miRNA Products:		OriGene 3'-UTR Clone: DHX35 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DHX35
		8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate DHX35 (see all 13):
		hsa-miR-142-5p hsa-miR-3163 hsa-miR-498 hsa-miR-4324 hsa-miR-610 hsa-miR-3688-3p hsa-miR-340 hsa-miR-544b

		SwitchGear 3'UTR luciferase reporter plasmid: DHX35 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DHX35 (see all 7) OriGene shRNA RFP: DHX35 OriGene siRNA: DHX35
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Gene Editing
Products:

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX35

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003676	nucleic acid binding	IEA	--
GO:0004386	helicase activity	--	--
GO:0005524	ATP binding	IEA	--
GO:0008026	ATP-dependent helicase activity	IEA	--

DHX35 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for DHX35:

Upregulation of Wnt/beta-caten

Animal Models:
1 MGI phenotypic allele

for Dhx35 (no phenotypes)

DHX35 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DHX35

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5 Interacting proteins for DHX35 (Q9H5Z1³ ENSP00000252011⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PLEKHF2	Q9H8W4³	I2D: score=4
UBC	ENSP00000344818⁴	STRING: ENSP00000344818
CDC40	ENSP00000304370⁴	STRING: ENSP00000304370
PRPF8	ENSP00000304350⁴	STRING: ENSP00000304350
DKC1	ENSP00000358563⁴	STRING: ENSP00000358563

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000398	mRNA splicing, via spliceosome	IC	11991638

DHX35 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DHX35
Search CenterWatch for drugs/clinical trials and news about DHX35

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DHX35 gene (2 alternative transcripts):

NM_001190809.1 NM_021931.3

Unigene Cluster for DHX35:

DEAH (Asp-Glu-Ala-His) box polypeptide 35

Hs.444520 [show with all ESTs]

Unigene Representative Sequence: NR_033905

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000373325 ENST00000252011(uc010zwa.2 uc002xjh.3 uc010zwc.2 uc010zwb.2)

ENST00000484417 ENST00000441485 ENST00000449559 ENST00000493450 ENST00000482619

ENST00000373323

miRNA Products:		OriGene 3'-UTR Clone: DHX35 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DHX35
		8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate DHX35 (see all 13):
		hsa-miR-142-5p hsa-miR-3163 hsa-miR-498 hsa-miR-4324 hsa-miR-610 hsa-miR-3688-3p hsa-miR-340 hsa-miR-544b

		SwitchGear 3'UTR luciferase reporter plasmid: DHX35 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector (see all 2): DHX35 (NM_021931)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DHX35
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Additional cDNA sequence:

AF086439.1 AK025541.1 AK026412.1 AK296506.1 AK296793.1 AK303396.1 AK307863.1 BC033453.1

BC059369.1 BC132669.1 BC143941.1 NR_033905.1

12 DOTS entries:

DT.113731 DT.421794 DT.92424323 DT.100780520 DT.92424324 DT.97824596 DT.97842482 DT.100023339

DT.120825735 DT.120825749 DT.95262497 DT.120825746

24/138 AceView cDNA sequences (see all 138):

AL521043 BM456216 BC033453 AL045984 AI810135 BM981992 NM_021931 CR617741

BM722257 BM768801 AI078553 AL521042 AI084458 AA994891 AI354824 CA454127

BQ213833 AI479647 BQ011761 AI917285 AA234779 CA445767 BQ011769 AA400227

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DHX35 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAATAATAG

About this image
See DHX35 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DHX35

SOURCE GeneReport for Unigene cluster: Hs.444520

SABiosciences Custom PCR Arrays for DHX35

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DHX35 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHX35

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX35

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for DHX35 gene from 8/31 species (see all 31) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	DHX35¹	DEAH (Asp-Glu-Ala-His) box polypeptide 35	79.77(n) 90.17(a)		419172 XM_417352.3 XP_417352.2
lizard (Anolis carolinensis)	Reptilia	DHX35⁶	--	89(a)	1 ↔ 1	4(140861525-140910276)
zebrafish (Danio rerio)	Actinopterygii	zgc:158828⁶	zgc:158828	77(a)	1 ↔ 1	23(2927690-2945990)
fruit fly (Drosophila melanogaster)	Insecta	CG3225¹	CG3225	54.73(n) 50.62(a)		33680 NM_135016.2 NP_608860.1
worm (Caenorhabditis elegans)	Secernentea	Y67D2.6¹	Protein Y67D2.6	56.68(n) 53.95(a)		175308 NM_065019.2 NP_497420.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT4G18465¹	ATP-dependent RNA helicase DDX35	55.01(n) 51.72(a)		827579 NM_117961.2 NP_567558.2
rice (Oryza sativa)	Liliopsida	Os01g0212100¹	hypothetical protein	54.27(n) 51.26(a)		4325567 NM_001048912.1 NP_001042377.1
E. coli (Escherichia coli)	Gamma proteobacteria	hrpB⁶ hrpA⁶	predicted ATP-dependent helicase	19(a) 17(a)	possible ortholog possible ortholog	Chromosome(162105-164534) Chromosome(1481085-1484987)

ENSEMBL Gene Tree for DHX35 (if available)
TreeFam Gene Tree for DHX35 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DHX35 gene

DHX40² YTHDC2² DHX57² DHX9² DHX29² DHX36² DHX30² TDRD9²

DHX33² DHX16² DHX38² DHX8²

11 SIMAP similar genes for DHX35 using alignment to 6 protein entries: DHX35_HUMAN (see all proteins):

DHX15 DHX16 DKFZp762F2011 DHX8 DHX33 DHX38

DHX40 DHX34 DHX36 DHX32 DQX1

DHX35 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs115687766^1,2		--	37588984(+)	`GTCCTC/TGTCCT`	3	--	us2k¹		1		WA	118
rs4810246^1,2	F,H,	--	37589016(+)	`GTGGCG/AGCAGG`	3	--	us2k¹		5		NS EA NA	538
rs190436013^1,2		--	37589031(+)	`CCACAA/GATCAA`	3	--	us2k¹		0	--	--	--	--
rs12480714^1,2	H	--	37589087(+)	`TAGGCA/TCTGTT`	3	--	us2k¹		0	--	--	--	--
rs138470991^1,2		--	37589170(+)	`AGTGGA/CGGCAG`	3	--	us2k¹		0	--	--	--	--
rs62204130^1,2		--	37589190(+)	`AGATCC/AACTAA`	3	--	us2k¹		2		NA CSA	3
rs56061147^1,2	C	--	37589194(+)	`CAACTA/GAAACT`	3	--	us2k¹		0	--	--	--	--
rs55650693^1,2	C	--	37589200(+)	`AAACTA/GAGCCT`	3	--	us2k¹		0	--	--	--	--
rs55908708^1,2	C	--	37589307(+)	`TAGTGA/GCGGCA`	3	--	us2k¹		0	--	--	--	--
rs139786084^1,2		--	37589389(+)	`TGGGCC/TACGAA`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for DHX35 (37590942 - 37668366 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DHX35: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DHX35

DNA2.0 Custom Variant and Variant Library Synthesis for DHX35

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DHX35 for disorders About MalaCards

DHX35 for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: DHX35 (1 document)

Export disorders for DHX35 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DHX35 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with DHX35)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)^{1, 2} Jurica M.S.... Moore M.J. (2002)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker o f susceptibility for bladder cancer. (PubMed id 21460395)¹ Gu J....Wu X. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (2011)
Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. (PubMed id 21546767)¹ Murea M....Freedman B.I. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)¹ Hutchins J.R....Peters J.M. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 60625	HGNC: 15861	AceView: DHX35	Ensembl:ENSG00000101452	euGenes: HUgn60625
ECgene: DHX35	H-InvDB: DHX35

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DHX35	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DHX35 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DHX35 gene:
Search GeneIP for patents involving DHX35

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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DHX35 Gene

DEAH (Asp-Glu-Ala-His) box polypeptide 35

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DHX35 Gene

DEAH (Asp-Glu-Ala-His) box polypeptide 35

Aliasesfor DHX35 gene

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Protein Domains /Familiesfor DHX35 gene

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for DHX35 gene

Disorders / Diseases
for DHX35 gene

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for DHX35 gene

Intellectual Property
for DHX35 gene

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for DHX35 gene