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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DHX34 Gene

protein-coding GIFtS: 54
GCID: GC19P047853

DEAH (Asp-Glu-Ala-His) box polypeptide 34

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 34 )
(Previous symbol: DDX34)

Explore 3 diseases affiliated with
DHX34 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
DEAH (Asp-Glu-Ala-His) Box Polypeptide 34¹ ²		HRH1²
DDX34¹ ² ³		Probable ATP-Dependent Helicase DHX34²
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 34¹ ²		Probable ATP-Dependent RNA Helicase DHX34²
KIAA0134¹ ³		EC 3.6.4.13³
DEAH Box Protein 34² ³		EC 3.6.1⁸

External Ids:	HGNC: 16719¹	Entrez Gene: 9704²	Ensembl: ENSG00000134815⁷	UniProtKB: Q14147³

Export aliases for DHX34 gene to outside databases

Previous GC identifers: GC19P052532 GC19P052547 GC19P052544 GC19P044277

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DHX34:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are

implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation

initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution

patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis,

and cellular growth and division. This gene encodes a member of this family. It is mapped to the glioma 19q tumor

suppressor region and is a tumor suppressor candidate gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DHX34_HUMAN, Q14147

Function: Probable ATP-binding RNA helicase

summary for DHX34:

Histamine H1 receptors are Galphaq/11-protein-coupled receptors that mediate allergic responses. These

receptors are expressed in a wide variety of tissues including the gastrointestinal tract, central nervous

system, airway and vascular smooth muscle cells, endothelial cells, chondrocytes, monocytes, neutrophils,

dendritic cells, T and B lymphocytes, adrenal medulla, and the cardiovascular and genitourinary systems. H1

receptor activation induces a wide range of biological responses due to their widespread distribution. In

smooth muscle, H1 activation increases tension and the contractile response, and in vascular endothelial

cells receptor activation increases cell permeability. In the adrenal medulla, histamine acting at H1

receptors stimulates both adrenalin and noradrenalin release. Furthermore, H1 activation induces

prostacyclin and platelet-activating factor synthesis, promotes von Willebrand factor and nitric oxide

release, liberates arachidonic acid from phospholipids, and causes vasodilation of capillaries and

arterioles. At a physiological level, H1 receptors are involved in a wide array of processes including

thermal regulation, memory and learning, and control of the sleep-wake cycle, food intake, and emotional and

aggressive behaviors. Histamine acting through the H1 receptor has proinflammatory effects, and is involved

in the development of various aspects of the antigen-specific immune response. Activation of these receptors

triggers maturation of dendritic cells and modulates the balance of Th1 and Th2 cells. H1 receptors are

involved in the pathological process of allergy, including allergic rhinits, atopic dermatitis, anaphylaxis

and asthma, and also have a role in autoimmune diseases and malignancy.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DHX34 gene promoter:
Msx-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DHX34 promoter sequence

Search SABiosciences Chromatin IP Primers for DHX34

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHX34

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.3 Ensembl cytogenetic band: 19q13.32 HGNC cytogenetic band: 19q13.3

DHX34 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHX34 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P047853: view genomic region (about GC identifiers)

Start:	47,852,538 bp from pter	End:	47,889,887 bp from pter
Size:	37,350 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DHX34_HUMAN, Q14147 (See protein sequence)

Recommended Name: Probable ATP-dependent RNA helicase DHX34

Size: 1143 amino acids; 128120 Da

Sequence caution: Sequence=BAA09483.2; Type=Miscellaneous discrepancy; Note=Aberrant splicing; Sequence=BAG60050.1;

Type=Erroneous initiation; Note=Translation N-terminally extended;

Secondary accessions: B4DMY8

Explore the universe of human proteins at neXtProt for DHX34: NX_Q14147

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q14147

4/6 DME Specific Peptides for DHX34 (Q14147) (see all 6)

TNIAETS

VDEVHER

GDTGCGK

VILMSAT

DHX34 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055496.2

ENSEMBL proteins:

ENSP00000331907 ENSP00000419670 ENSP00000418656

Human Recombinant Protein Products for DHX34:

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	Uscn Proteins for DHX34

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--

DHX34 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for DHX34

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DHX34 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR007502 Helicase-assoc_dom

IPR015880 Znf_C2H2-like

IPR011545 DNA/RNA_helicase_DEAD/DEAH_N

IPR011709 DUF1605

IPR014001 Helicase_ATP-bd

Graphical View of Domain Structure for InterPro Entry Q14147

ProtoNet protein and cluster: Q14147

1 Blocks protein family: IPB002464 ATP-dependent helicase

UniProtKB/Swiss-Prot: DHX34_HUMAN, Q14147

Similarity: Belongs to the DEAD box helicase family. DEAH subfamily

Similarity: Contains 1 helicase ATP-binding domain

Similarity: Contains 1 helicase C-terminal domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: DHX34_HUMAN, Q14147

Function: Probable ATP-binding RNA helicase

Catalytic activity: ATP + H(2)O = ADP + phosphate

Enzyme Numbers (IUBMB): EC 3.6.1² EC 3.6.4.13¹

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003723	RNA binding	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0008026	ATP-dependent helicase activity	IEA	--
GO:0008270	zinc ion binding	IEA	--

DHX34 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for DHX34:

Decreased Wnt reporter activit

Proliferating cells

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DHX34

miRNA Products:		miRTarBase miRNAs that target DHX34: hsa-mir-192 (MIRT004851)

		OriGene 3'-UTR Clone: DHX34 Browse MicroRNA Expression Plasmids
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DHX34 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DHX34 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX34

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DHX34

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

4 Interacting proteins for DHX34 (Q14147^{2, 3} ENSP00000331907⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GSK3B	P49841²^,³	MINT-8257097 I2D: score=2
RPS6KA6	Q9UK32²^,³	MINT-8269802 I2D: score=2
POLA2	Q14181³, ENSP00000265465⁴	I2D: score=3 STRING: ENSP00000265465
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Compounds for DHX34 available from Tocris Bioscience About this table

Compound	Action	CAS #
HTMT dimaleate	H1 / H2 agonist	[195867-54-0]
Olopatadine hydrochloride	H1 antagonist; ocular antiallergic agent	[140462-76-6]
Loratidine	Peripheral H1 antagonist; antiallergic agent	[79794-75-5]
Fexofenadine hydrochloride	H1 receptor antagonist; non-sedating antiallergic agent	[153439-40-8]
2-Pyridylethylamine dihydrochloride	H1 receptor agonist	[3343-39-3]

Search CenterWatch for drugs/clinical trials and news about DHX34

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DHX34 gene (2 alternative transcripts):

NM_014681.5 NM_194428.1

Unigene Cluster for DHX34:

DEAH (Asp-Glu-Ala-His) box polypeptide 34

Hs.151706 [show with all ESTs]

Unigene Representative Sequence: NM_014681

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000328771(uc010xyn.2 uc010elc.1 uc010xyo.1) ENST00000466298

ENST00000471451 ENST00000486327 ENST00000460681

miRNA Products:		OriGene 3'-UTR Clone: DHX34 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DHX34
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DHX34 (see all 4) OriGene shRNA RFP: DHX34 OriGene siRNA: DHX34
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		Sirion Biotech Custom design and validation of potent shRNA sequences against DHX34

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHX34

Additional cDNA sequence:

AK297692.1 AK304710.1 BC035243.1 BC131800.1

11 DOTS entries:

DT.415547 DT.97861838 DT.95136472 DT.101983357 DT.95073840 DT.92428633 DT.100682534 DT.121504156

DT.415548 DT.65288301 DT.92428635

24/181 AceView cDNA sequences (see all 181):

BE677798 CF125570 AI949021 BF434827 CN478682 NM_194428 BQ708034 NM_014681

BQ643547 CF125167 AI571106 BQ939671 BI907836 BI771633 BF436543 BI830752

BX343193 BM811498 AW297881 BQ109391 AA329366 AA970468 BX355295 AI017634

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for DHX34 (see all 10) About this scheme

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b	^	7	^	8	^	9	^	10a	·	10b	^	11a	·	11b	^	12a	·	12b	^	13	^	14	^	15a	·	15b	^	16	^	17	^	18	^	19	^
SP1:
SP2:
SP3:
SP4:
SP5:

ExUns:	20	^	21	^	22	^	23
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for DHX34

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DHX34 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGATAAAAA

About this image

DHX34 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Human umbilical vein endothelial cells (HUVEC) (Primary Cell)

Endothelium

CD31, CD144 positive cells (Two-step protocol fo...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DHX34 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DHX34

SOURCE GeneReport for Unigene cluster: Hs.151706

SABiosciences Custom PCR Arrays for DHX34

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DHX34 Browse OriGene validated miRNA SYBR primer pairs
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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX34

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for DHX34 gene from 4/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	DHX34⁶	--	68(a)	1 ↔ 1	LGf(1641610-1658927)
zebrafish (Danio rerio)	Actinopterygii	dhx34¹	DEAH (Asp-Glu-Ala-His) box polypeptide 34	62.56(n) 61.75(a)		555838 NM_001128333.1 NP_001121805.1
fruit fly (Drosophila melanogaster)	Insecta	CG32533¹	CG32533	54.99(n) 45.95(a)		32933 NM_167649.1 NP_728244.1
worm (Caenorhabditis elegans)	Secernentea	smgl-2¹	Protein SMGL-2	49.83(n) 46.65(a)		177135 NM_068004.4 NP_500405.2

ENSEMBL Gene Tree for DHX34 (if available)
TreeFam Gene Tree for DHX34 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DHX34 gene

8 SIMAP similar genes for DHX34 using alignment to 3 protein entries: DHX34_HUMAN (see all proteins):

DKFZp762F2011 DHX40 DHX16 DHX35 DHX15 DHX38

DHX8 DHX33

DHX34 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for DHX34
PGOHUM00000238302

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs191343286^1,2		--	47850600(+)	`TATTTA/GTTTGT`	1	--	us2k¹		0	--	--	--	--
rs60913612^1,2	C	--	47850603(+)	`TATTTATTT/- GTTTG`	1	--	us2k¹		1		NA	2
rs55854871^1,2	C	--	47850604(+)	`TATTTA/GTTTGT`	1	--	us2k¹		0	--	--	--	--
rs113120596^1,2		--	47850618(+)	`TTTATC/TTGAGA`	1	--	us2k¹		2		CSA	3
rs149595384^1,2		--	47850627(+)	`GACAGA/GGTTTC`	1	--	us2k¹		0	--	--	--	--
rs146090128^1,2		--	47850640(+)	`CTTGTC/TGCCCA`	1	--	us2k¹		0	--	--	--	--
rs188000233^1,2		--	47850834(+)	`CTGACC/TTCAGG`	1	--	us2k¹		0	--	--	--	--
rs111712972^1,2		--	47850841(+)	`CAGGTG/AATCCA`	1	--	us2k¹		2		CSA	2
rs142148711^1,2		--	47850912(+)	`TTGGAA/CATTTT`	1	--	us2k¹		0	--	--	--	--
rs11669859^1,2	C,F,H	--	47850914(+)	`GGAAAT/CTTTAA`	1	--	us2k¹ tfbs³		8		NS EA WA NA	772

HapMap Linkage Disequilibrium report for DHX34 (47852538 - 47889887 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for DHX34
3 CNVs: 4083 30911 50184

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DHX34

DNA2.0 Custom Variant and Variant Library Synthesis for DHX34

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DHX34 for disorders About GeneDecksing

3 diseases for DHX34: About MalaCards

atopic dermatitis dermatitis asthma

Export disorders for DHX34 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DHX34 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with DHX34)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)^{1, 2, 3} Nagase T....Nomura N. (1995)
A transcript map of the chromosome 19q-Arm glioma tumor suppressor region. (PubMed id 10708517)^{1, 3} Smith J.S.... Jenkins R.B. (2000)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)¹ Vinayagam A....Wanker E.E. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 9704	HGNC: 16719	AceView: DHX34	Ensembl:ENSG00000134815	euGenes: HUgn9704
ECgene: DHX34	H-InvDB: DHX34

(According to HUGE)
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HUGE: KIAA0134

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DHX34	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for DHX34	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for DHX34 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for DHX34 gene:
Search GeneIP for patents involving DHX34

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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DHX34 Gene

DEAH (Asp-Glu-Ala-His) box polypeptide 34

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DHX34 Gene

DEAH (Asp-Glu-Ala-His) box polypeptide 34

Aliasesfor DHX34 gene

Summariesfor DHX34 gene

Genomic Viewsfor DHX34 gene

Proteinsfor DHX34 gene

Protein Domains /Familiesfor DHX34 gene

Functionfor DHX34 gene

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Expression for DHX34 gene

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Disorders / Diseasesfor DHX34 gene

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Genome Databases showing DHX34 gene

Other Databases showing DHX34 gene

Specialized Databases showing DHX34 gene

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for DHX34 gene

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for DHX34 gene

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for DHX34 gene

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for DHX34 gene

Protein Domains /
Families
for DHX34 gene

Function
for DHX34 gene

Pathways & Interactions
for DHX34 gene

Drugs & Compounds
for DHX34 gene

Transcripts
for DHX34 gene

Expression
for DHX34 gene

Orthologs
for DHX34 gene

Paralogs
for DHX34 gene

Genomic Variants
for DHX34 gene

Disorders / Diseases
for DHX34 gene

Publications
for DHX34 gene

Intellectual Property
for DHX34 gene

Products
for DHX34 gene