Aliases for DHX33 Gene
External Ids for DHX33 Gene
Previous HGNC Symbols for DHX33 Gene
Previous GeneCards Identifiers for DHX33 Gene
This gene encodes a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
GeneCards Summary for DHX33 Gene
DHX33 (DEAH-Box Helicase 33) is a Protein Coding gene. Among its related pathways are Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is DHX8.
UniProtKB/Swiss-Prot for DHX33 Gene
Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization.