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DHX32 Gene

protein-coding GIFtS: 51
GCID: GC10M127515

DEAH (Asp-Glu-Ala-His) Box Polypeptide 32

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32)
(Previous symbol: DDX32)

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
DEAH (Asp-Glu-Ala-His) Box Polypeptide 32¹ ²		DEAD/H Helicase-Like Protein-1²
DDX32¹ ² ³ ⁵		huDDX32²
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 32¹ ²		Putative Pre-MRNA-Splicing Factor ATP-Dependent RNA Helicase DHX32²
DHLP1² ³		EC 3.6.4.13³
DEAD/H Box 32² ³		HuDDX32³
DEAD/H Helicase-Like Protein 1² ³		EC 3.6.1⁸
DEAH Box Protein 32² ³

External Ids:	HGNC: 16717¹	Entrez Gene: 55760²	Ensembl: ENSG00000089876⁷	OMIM: 607960⁵	UniProtKB: Q7L7V1³

Export aliases for DHX32 gene to outside databases

Previous GC identifers: GC10M127099 GC10M121214

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DHX32 Gene:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They

are implicated in a number of cellular processes involving alteration of RNA secondary structure such as

translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their

distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis,

spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of

this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the

full length nature of one of the variants has not been defined. (provided by RefSeq, Jul 2008)

GeneCards Summary for DHX32 Gene:

DHX32 (DEAH (Asp-Glu-Ala-His) box polypeptide 32) is a protein-coding gene. Diseases associated with DHX32 include brain cancer, and breast and colorectal cancer. GO annotations related to this gene include helicase activity. An important paralog of this gene is DHX33.

Gene Wiki entry for DHX32 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000010.11 NC_018921.2 NT_030059.14

Regulatory elements:

Regulatory transcription factor binding sites in the DHX32 gene promoter:
RFX1 Spz1 NRSF form 1 SREBP-1c NRSF form 2 YY1 SREBP-1b N-Myc SREBP-1a FOXO4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DHX32 promoter sequence

Search Chromatin IP Primers for DHX32

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DHX32

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.2 Ensembl cytogenetic band: 10q26.2 HGNC cytogenetic band: 10q26.11-q26.2

DHX32 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHX32 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M127515: view genomic region (about GC identifiers)

Start:	127,524,906 bp from pter	End:	127,585,005 bp from pter
Size:	60,100 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: DHX32_HUMAN, Q7L7V1 (See protein sequence)

Recommended Name: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

Size: 743 amino acids; 84419 Da

Sequence caution: Sequence=AAH37925.1; Type=Frameshift; Positions=439; Sequence=BAB15029.1; Type=Erroneous

initiation;

Secondary accessions: A8MSV2 D3DRF9 Q49AG5 Q5T3L0 Q5T3L5 Q96NY1 Q9BUN0 Q9H769 Q9NSL5 Q9NV74

Q9NVJ7

Alternative splicing: 2 isoforms: Q7L7V1-1 Q7L7V1-2

Explore the universe of human proteins at neXtProt for DHX32: NX_Q7L7V1

Explore proteomics data for DHX32 at MOPED

Post-translational modifications:

Ubiquitination² at Lys596

Modification sites at PhosphoSitePlus

3 DME Specific Peptides for DHX32 (Q7L7V1)

EFPLDPQL

IMSEFPLDPQ

ALEDLDYLAAL

See DHX32 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_060650.2

ENSEMBL proteins:

ENSP00000357710 ENSP00000284690 ENSP00000406781 ENSP00000284688

DHX32 Human Recombinant Protein Products:

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	Novus Biologicals DHX32 Proteins Novus Biologicals DHX32 Lysate
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	Cloud-Clone Corp. Proteins for DHX32

DHX32 Antibody Products:

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	LSBio Antibodies in human, mouse, rat for DHX32

DHX32 Assay Products:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for DHX32
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	Cloud-Clone Corp. ELISAs for DHX32 Cloud-Clone Corp. CLIAs for DHX32

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

DHX: DEAH-boxes

4 InterPro protein domains:

IPR007502 Helicase-assoc_dom

IPR011709 DUF1605

IPR027417 P-loop_NTPase

IPR014001 Helicase_ATP-bd

Graphical View of Domain Structure for InterPro Entry Q7L7V1

ProtoNet protein and cluster: Q7L7V1

1 Blocks protein domain: IPB007502 Helicase-associated region

UniProtKB/Swiss-Prot: DHX32_HUMAN, Q7L7V1

Similarity: Belongs to the DEAD box helicase family. DEAH subfamily

Similarity: Contains 1 helicase ATP-binding domain

Similarity: Contains 1 helicase C-terminal domain

DHX32 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: DHX32_HUMAN, Q7L7V1

Catalytic activity: ATP + H(2)O = ADP + phosphate

Induction: Up-regulated by ionomycin in T-lymphocytes. Down-regulated in acute lymphoblastic leukemia

Enzyme Numbers (IUBMB): EC 3.6.1² EC 3.6.4.13¹

Gene Ontology (GO): 2 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004386	helicase activity	IEA	--
GO:0005524	ATP binding	IEA	--

DHX32 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for DHX32:

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DHX32

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DHX32

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DHX32

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DHX32

miRNA Products:		miRTarBase miRNAs that target DHX32: hsa-mir-335-5p (MIRT018169)

		Block miRNA regulation of human, mouse, rat DHX32 using miScript Target Protectors
		6 qRT-PCR Assays for microRNAs that regulate DHX32:
		hsa-miR-548am hsa-miR-1283 hsa-miR-548x hsa-miR-642b hsa-miR-548n hsa-miR-3133
		SwitchGear 3'UTR luciferase reporter plasmid: DHX32 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for DHX32
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Gene Editing
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		GenScript: all cDNA clones in your preferred vector: DHX32 (NM_018180)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX32

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

DHX32_HUMAN, Q7L7V1: Nucleus. Mitochondrion

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
mitochondrion	5
nucleus	5

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Gene Ontology (GO): 2 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005739	mitochondrion	IEA	--

DHX32 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for DHX32
Interactions:

Search GeneGlobe Interaction Network for DHX32

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for DHX32 (ENSP00000284690⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 178)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NOP58	ENSP00000264279⁴	STRING: ENSP00000264279
PLRG1	ENSP00000303191⁴	STRING: ENSP00000303191
PRPF19	ENSP00000227524⁴	STRING: ENSP00000227524
CRNKL1	ENSP00000366557⁴	STRING: ENSP00000366557
DHX38	ENSP00000268482⁴	STRING: ENSP00000268482

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for DHX32

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for DHX32 gene:

NM_018180.2

Unigene Cluster for DHX32:

DEAH (Asp-Glu-Ala-His) box polypeptide 32

Hs.370292 [show with all ESTs]

Unigene Representative Sequence: AF427340

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000368721(uc001lje.1) ENST00000284690(uc001ljf.1 uc001ljg.1)

ENST00000415732 ENST00000284688(uc009yam.1)

miRNA Products:		Block miRNA regulation of human, mouse, rat DHX32 using miScript Target Protectors
		6 qRT-PCR Assays for microRNAs that regulate DHX32:
		hsa-miR-548am hsa-miR-1283 hsa-miR-548x hsa-miR-642b hsa-miR-548n hsa-miR-3133
		SwitchGear 3'UTR luciferase reporter plasmid: DHX32 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for DHX32
		Predesigned siRNA for gene silencing in human, mouse, rat DHX32

Clone Products:		OriGene clones in human, mouse for DHX32 (see all 6) OriGene ORF clones in mouse, rat for DHX32 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DHX32 (NM_018180)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DHX32
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DHX32

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for DHX32
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat DHX32
		QuantiTect SYBR Green Assays in human, mouse, rat DHX32
		QuantiFast Probe-based Assays in human, mouse, rat DHX32

Additional mRNA sequence:

AF427340.1 AF427341.1 AK001556.1 AK001751.1 AK024869.1 AK315430.1 AL162051.1 AY064250.1

BC002473.2 BC037925.1 BC068471.1

11 DOTS entries:

DT.95322273 DT.95351362 DT.450133 DT.97785236 DT.92466957 DT.92466941 DT.121252111 DT.92466960

DT.95256388 DT.100038056 DT.121252122

Selected AceView cDNA sequences (see all 175):

CD244959 BU623127 BM979010 BU730233 BM068824 BM766385 F08130 AF427340

CA422102 AI632405 BU632131 BM741863 H94915 AA570125 AA293266 BC002473

BM822980 BE782153 CA430535 NM_018180 BM967310 BM893963 AA742522 AI887598

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for DHX32 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b	·	5c	^	6a	·	6b	^	7
SP1:																					-
SP2:							-		-		-				-
SP3:							-
SP4:							-		-		-										-
SP5:

ECgene alternative splicing isoforms for DHX32

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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DHX32 expression in normal human tissues (normalized intensities) DHX32 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

DHX32 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 5) fully expand


Brain (Nervous System) fully expand to see all 3 entries
Cerebral Cortex

Ovary (Reproductive System) fully expand to see all 2 entries
Ovarian Mesenchymal Stroma Cells Ovary Interstitium
Oviduct

Trophoblast (Extraembryonic Tissues)
Trophoblast Cells Trophoblast

Testis (Reproductive System)
Leydig Cells Testis Interstitium

Liver (Hepatobiliary System)
Hepatocytes Liver Lobule

DHX32 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

DHX32 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.370292

UniProtKB/Swiss-Prot: DHX32_HUMAN, Q7L7V1

Tissue specificity: Expressed in lymphoid tissues (at protein level). Expressed in brain, heart, skeletal muscle,

colon, thymus, spleen, kidney, liver, small intestine, placenta, lung, lymphoid tissues and blood leukocytes

Custom PCR Arrays for DHX32

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX32

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for DHX32 gene from Selected species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Dhx32^{1 , 5}	DEAH (Asp-Glu-Ala-His) box polypeptide 32^{1, 5}	83.51(n)¹ 88.14(a)¹		7 (77.32 cM)⁵ 101437¹ NM_001286031.1¹ NP_001272960.1¹ 133720942⁵
chicken (Gallus gallus)	Aves	LOC768812¹	putative pre-mRNA-splicing factor ATP-dependent RNA more	69.71(n) 69.58(a)		768812 XM_003641504.2 XP_003641552.1
African clawed frog (Xenopus laevis)	Amphibia	48053821²	--	74.21(n)		48053821
zebrafish (Danio rerio)	Actinopterygii	57093361²	--	69.72(n)		57093361
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	PRP43⁶	RNA helicase in the DEAH-box family, functions in ...	34(a)	1 → many	VII(281634-283937) YGL120C

ENSEMBL Gene Tree for DHX32 (if available)
TreeFam Gene Tree for DHX32 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for DHX32 gene

DHX33² DHX16² DHX35² DHX15² DQX1² DHX8²

7 SIMAP similar genes for DHX32 using alignment to 1 protein entry: DHX32_HUMAN:

DHX15 DQX1 DHX8 DHX16 DHX38 DHX33

DHX35

DHX32 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
VAR_035843⁴		A breast cancer sample⁴	--	see VAR_035843	2	P R	mis⁴		0	--	--	--	--
rs181211770^1,2		--	127542909(+)	`CCTACA/GTGTAT`	1	--	int¹		0	--	--	--	--
rs185306093^1,2		--	127543025(+)	`TAAGTA/GAAAAA`	1	--	int¹		0	--	--	--	--
rs189803957^1,2		--	127543139(+)	`ATTAAA/CTCAAG`	1	--	int¹		0	--	--	--	--
rs181898536^1,2		--	127543304(+)	`GGTACA/GGTCCC`	1	--	int¹		0	--	--	--	--
rs143028388^1,2		--	127543602(+)	`ATCCTG/TGCCAA`	1	--	int¹		0	--	--	--	--
rs186883413^1,2		--	127543625(+)	`CTGTCG/TACTAA`	1	--	int¹		0	--	--	--	--
rs192079012^1,2		--	127543663(+)	`GCATGA/CGTCTG`	1	--	int¹		0	--	--	--	--
rs112166585^1,2	C,F	--	127543664(+)	`CATGCG/ATCTGT`	1	--	int¹		2		WA	120
rs113676877^1,2	F	--	127543689(+)	`ACAAGG/TCTGAG`	1	--	int¹		1		CSA	2

HapMap Linkage Disequilibrium report for DHX32 (127524906 - 127585005 bp)

Structural Variations
Database of Genomic Variants (DGV) 3 variations for DHX32: About this table

Variant ID	Type	Subtype	PubMed ID
nsv428241	CNV	Loss	18775914
nsv8737	CNV	Loss	18304495
dgv324e1	CNV	Complex	17122850

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing DHX32

DNA2.0 Custom Variant and Variant Library Synthesis for DHX32

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 607960 OMIM disorders: --

10 diseases for DHX32: About MalaCards

brain cancer breast and colorectal cancer lymphoblastic leukemia colorectal cancer

tonsillitis leukemia cerebritis thyroiditis

endotheliitis prostatitis

DHX32 for disorders About GeneDecksing

Genetic Association Database (GAD): DHX32

Export disorders for DHX32 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for DHX32 gene, integrated from 10 sources (see all 21):
(articles sorted by number of sources associating them with DHX32)

Utopia: connect your pdf to the dynamic
world of online information

Genomic structure of the human BCCIP gene and its expression in cancer. (PubMed id 12527204)^{1, 2, 9} Meng X.... Shen Z. (Gene 2003)
Nuclear and mitochondrial localization of the putative RNA helicase DHX32. (PubMed id 16959245)^{1, 2} Alli Z.... Abdelhaleem M. (Exp. Mol. Pathol. 2006)
The activation-induced expression of DHX32 in Jurkat T cells is specific and involves calcium and nuclear factor of activated T cells. (PubMed id 16414036)^{1, 2} Alli Z.... Abdelhaleem M. (Cell. Immunol. 2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
The novel helicase homologue DDX32 is down-regulated in acute lymphoblastic leukemia. (PubMed id 12163057)^{1, 2} Abdelhaleem M. (Leuk. Res. 2002)
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)¹ Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)² Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (amp 2011)
Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (Mol. Cell 2011)
Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (amp 2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 55760	HGNC: 16717	AceView: DHX32	Ensembl:ENSG00000089876	euGenes: HUgn55760
ECgene: DHX32	H-InvDB: DHX32

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for DHX32	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DHX32 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for DHX32 gene:
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DHX32 Gene

DEAH (Asp-Glu-Ala-His) Box Polypeptide 32

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DHX32 Gene

DEAH (Asp-Glu-Ala-His) Box Polypeptide 32

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