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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DHX16 Gene

protein-coding   GIFtS: 62
GCID: GC06M030620

DEAH (Asp-Glu-Ala-His) Box Polypeptide 16

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16)
(Previous symbol: DDX16)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DEAH (Asp-Glu-Ala-His) Box Polypeptide 161 2     PRPF22
DDX161 2 3 5     Prp22
DBP22 3 5     DEAD/H Box 162
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 161 2     Putative Pre-MRNA-Splicing Factor ATP-Dependent RNA Helicase DHX162
ATP-Dependent RNA Helicase #32 3     RNA Helicase2
DEAH-Box Protein 162 3     EC 3.6.4.133
PRP82 5     KIAA05773
PRO20142     EC 3.6.18

External Ids:    HGNC: 27391   Entrez Gene: 84492   Ensembl: ENSG000002045607   OMIM: 6034055   UniProtKB: O602313   

Export aliases for DHX16 gene to outside databases

Previous GC identifers: GC06M030391 GC06M030727 GC06M030728


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DHX16 Gene:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They
are implicated in a number of cellular processes involving alteration of RNA secondary structure such as
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their
distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis,
and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission
yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome
6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants
encoding different isoforms have been found for this gene. (provided by RefSeq, Aug 2009)

GeneCards Summary for DHX16 Gene: 
DHX16 (DEAH (Asp-Glu-Ala-His) box polypeptide 16) is a protein-coding gene. Diseases associated with DHX16 include esophageal adenocarcinoma, and systemic lupus erythematosus, and among its related super-pathways are Processing of Capped Intron-Containing Pre-mRNA. GO annotations related to this gene include RNA helicase activity and nucleic acid binding. An important paralog of this gene is DHX33.

UniProtKB/Swiss-Prot: DHX16_HUMAN, O60231
Function: Probable ATP-binding RNA helicase involved in pre-mRNA splicing

Gene Wiki entry for DHX16 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  NT_113891.2  NT_167244.1  NT_167245.1  NT_167246.1  NT_167247.1  
NT_167248.1  NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DHX16 gene promoter:
         TBP   AML1a   NF-kappaB   E47   Max   NF-kappaB2   ARP-1   Hand1   NF-kappaB1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DHX16 promoter sequence
   Search SABiosciences Chromatin IP Primers for DHX16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHX16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.3

DHX16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHX16 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M030620:  view genomic region     (about GC identifiers)

Start:
30,620,896 bp from pter      End:
30,640,830 bp from pter
Size:
19,935 bases      Orientation:
minus strand

6/7 alternative locations (see all 7):
Chr6-,NT_167247 2,002,754-2,022,715      Chr6-,NT_167244 1,938,870-1,952,475      Chr6-,NT_167246 1,968,963-1,988,926     
Chr6-,NT_167245 1,914,527-1,934,492      Chr6-,NT_167249 1,953,168-1,973,134      Chr6-,NT_167248 1,913,797-1,933,762     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DHX16_HUMAN, O60231 (See protein sequence)
Recommended Name: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16  
Size: 1041 amino acids; 119264 Da
Subcellular location: Nucleus
Sequence caution: Sequence=BAA25503.2; Type=Erroneous initiation;
Secondary accessions: O60322 Q5JP45 Q969X7 Q96QC1

Explore the universe of human proteins at neXtProt for DHX16: NX_O60231

Explore proteomics data for DHX16 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O60231

  • 4/16 DME Specific Peptides for DHX16 (O60231) (see all 16)
     TNIAETS  VGYSIRF  FLTGQEE  TVPEIQR 

    DHX16 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DHX16 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001157711.1  NP_003578.2  

    ENSEMBL proteins: 
     ENSP00000365620   ENSP00000365625   ENSP00000399101  

    Human Recombinant Protein Products for DHX16: 
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    Novus Biologicals DHX16 Protein
    Novus Biologicals DHX16 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DHX16 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    DHX16 for ontologies           About GeneDecksing



    DHX16 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for DHX16


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DHX: DEAH-boxes

    5/7 InterPro protein domains (see all 7):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR002464 DNA/RNA_helicase_DEAH_CS
     IPR007502 Helicase-assoc_dom
     IPR011709 DUF1605
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry O60231

    ProtoNet protein and cluster: O60231

    2 Blocks protein domains:
    IPB002464 ATP-dependent helicase
    IPB007502 Helicase-associated region


    UniProtKB/Swiss-Prot: DHX16_HUMAN, O60231
    Similarity: Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    DHX16 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DHX16_HUMAN, O60231
    Function: Probable ATP-binding RNA helicase involved in pre-mRNA splicing
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0003724RNA helicase activity TAS9547260
    GO:0004386helicase activity ----
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--
         
    DHX16 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DHX16 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DHX16 
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate DHX16:
    hsa-miR-188-3p hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidDHX16 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX16


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DHX16 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    mRNA processing0.46
    Spliceosome0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for DHX16
        mRNA processing


    1         Kegg Pathway  (Kegg details for DHX16):
        Spliceosome


    DHX16 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DHX16

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/23 Interacting proteins for DHX16 (O602312, 3 ENSP000003656254) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COILP384322, 3, ENSP000002403164MINT-2865160 I2D: score=3 STRING: ENSP00000240316
    DHX38Q926202, 3MINT-8331635 MINT-8337640 I2D: score=1 
    MEGF10Q96KG73, ENSP000002744734I2D: score=2 STRING: ENSP00000274473
    GPKOWQ929172MINT-8337662 MINT-8331646
    SF3B2Q134352MINT-8332361 MINT-8333614
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006397mRNA processing IEA--
    GO:0008380RNA splicing IEA--

    DHX16 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DHX16

    1 HMDB Compound for DHX16    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--

    Search CenterWatch for drugs/clinical trials and news about DHX16

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DHX16 gene (2 alternative transcripts): 
    NM_001164239.1  NM_003587.4  

    Unigene Cluster for DHX16:

    DEAH (Asp-Glu-Ala-His) box polypeptide 16
    Hs.485060  [show with all ESTs]
    Unigene Representative Sequence: NM_003587
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376437(uc003nqy.3) ENST00000376442(uc011dmo.2 uc003nqz.3)
    ENST00000480966 ENST00000415603
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DHX16
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate DHX16:
    hsa-miR-188-3p hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidDHX16 3' UTR sequence
    Inhib. RNA
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    Sirion Biotech Customized lentivirus for stable overexpression of DHX16 
                         Customized lentivirus expression plasmids for stable overexpression of DHX16 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for DHX16
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DHX16
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHX16

    Additional mRNA sequence: 

    AB001601.1 AF119860.1 AK302721.1 AK312264.1 BC002789.2 BC008825.2 BC009392.2 

    15 DOTS entries:

    DT.97860002  DT.100787658  DT.91998700  DT.121360219  DT.40130931  DT.100030798  DT.100786921  DT.97860004 
    DT.100786930  DT.97860003  DT.91901099  DT.121360333  DT.100650943  DT.100733165  DT.95226768 

    19 AceView cDNA sequences:

    BC002789 BC009392 BC008825 AF119860 CR591941 BQ311555 AB001601 BG315341 
    NM_003587 AA492431 BE839261 BQ333691 AW610220 BQ292037 BE708164 AB011149 
    BF375726 BQ311619 BQ315816 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DHX16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTAAGAAAAT
    DHX16 Expression
    About this image


    See DHX16 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DHX16

    SOURCE GeneReport for Unigene cluster: Hs.485060
        SABiosciences Custom PCR Arrays for DHX16
    Primer
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DHX16 gene from 9/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dhx161 , 5 DEAH (Asp-Glu-Ala-His) box polypeptide 161, 5 88.17(n)1
    96.15(a)1
      17 (18.74 cM)5
    691921  NM_026987.21  NP_081263.21 
     358798195 
    lizard
    (Anolis carolinensis)
    Reptilia DHX166
    DEAH (Asp-Glu-Ala-His) box polypeptide 16
    75(a)
    1 ↔ 1
    2(192116099-192148981)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.37512 Xenopus laevis transcribed sequence with moderate similarity more 74.36(n)    BJ072880.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa91b122 wufa91b12 76.27(n)   336645  BC045393.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)37Cb1 lethal (2) 37Cb 65.68(n)
    66.89(a)
      35192  NM_136102.3  NP_609946.1 
    worm
    (Caenorhabditis elegans)
    Secernentea mog-41 Protein MOG-4 57.45(n)
    57.72(a)
      175117  NM_064626.3  NP_497027.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PRP2(YNR011C)4
    PRP21
    RNA-dependent ATPase in the DEAH-box family, required more4
    Prp2p1
    50.61(n)1
    50.07(a)1
      14(646950-644320)4
    8557451, 4  NP_014408.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ESP31 pre-mRNA-splicing factor ATP-dependent RNA helicase more 56.62(n)
    56.43(a)
      840143  NM_102984.4  NP_174527.2 
    rice
    (Oryza sativa)
    Liliopsida Os05g03898001 hypothetical protein 58.44(n)
    54.45(a)
      4338675  NM_001061972.1  NP_001055437.1 


    ENSEMBL Gene Tree for DHX16 (if available)
    TreeFam Gene Tree for DHX16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DHX16 gene
    DHX332  DHX402  DHX352  DHX152  DHX382  DHX82  DHX342  
    11 SIMAP similar genes for DHX16 using alignment to 8 protein entries:     DHX16_HUMAN (see all proteins):
    DHX8    DHX38    DHX15    DHX35    DHX33    DKFZp762F2011
    DHX32    DHX40    DHX34    DQX1    DHX30

    DHX16 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/360 SNPs in DHX16 are shown (see all 360)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0572384
    ----see VAR_0572382 D G mis40--------
    VAR_0572364
    ----see VAR_0572362 K E mis40--------
    VAR_0572374
    ----see VAR_0572372 L F mis40--------
    rs1469615101,2
    --30621525(+) GCCTGA/GCTCTA 2 -- int10--------
    rs1916886491,2
    --30621631(+) CAGTGC/GCTCAC 2 -- int10--------
    rs1830404411,2
    --30621644(+) CTGTAA/GTCCCA 2 -- int10--------
    rs1863172791,2
    --30621664(+) GAGGCC/TGTGGC 2 -- int10--------
    rs1899046531,2
    --30621789(+) TACACC/TGGAGG 2 -- int10--------
    rs612300471,2
    C--30621835(+) GGTTG-/CA    
       TGAGC
    TGAGA
    2 -- int10--------
    rs1821749851,2
    --30621869(+) AGCCTG/TGGCTA 2 -- int10--------

    HapMap Linkage Disequilibrium report for DHX16 (30620896 - 30640830 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for DHX16:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2670269CNV Deletion23128226
    esv2731791CNV Deletion23290073
    nsv884094CNV Loss21882294
    nsv830626CNV Loss17160897
    nsv823472CNV Gain20364138
    nsv884086CNV Gain21882294


    Human Gene Mutation Database (HGMD): DHX16
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DHX16
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603405    OMIM disorders: --

    5 diseases for DHX16:    About MalaCards
    esophageal adenocarcinoma    systemic lupus erythematosus    lupus erythematosus    esophagitis
    adenocarcinoma


    DHX16 for disorders           About GeneDecksing

    Genetic Association Database (GAD): DHX16
    Human Genome Epidemiology (HuGE) Navigator: DHX16 (3 documents)

    Export disorders for DHX16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DHX16 gene, integrated from 9 sources (see all 40):
    (articles sorted by number of sources associating them with DHX16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a human DEAH-box RNA helicase, a functional homolog of fission yeast Cdc28/Prp8. (PubMed id 9547260)1, 2, 3, 9 Imamura O.... Furuichi Y. (1998)
    2. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (2010)
    3. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (2009)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2 Nagase T....Ohara O. (1998)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Dynamic protein-protein interaction wiring of the huma n spliceosome. (PubMed id 22365833)1 Hegele A....Stelzl U. (2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8449 HGNC: 2739 AceView: DHX16 Ensembl:ENSG00000204560 euGenes: HUgn8449
    ECgene: DHX16 Kegg: 8449 H-InvDB: DHX16

    (According to HUGE)
    About This Section
    HUGE: KIAA0577

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DHX16 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DHX16 gene:
    Search GeneIP for patents involving DHX16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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