Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DHRS7 Gene

protein-coding GIFtS: 50
GCID: GC14M060610

dehydrogenase/reductase (SDR family) member 7

Explore 4 diseases affiliated with
DHRS7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Dehydrogenase/Reductase (SDR Family) Member 7¹ ²		RETSDR4³ ⁵
SDR34C1¹ ²		Dehydrogenase/Reductase SDR Family Member 7²
RetDSR4¹		Short Chain Dehydrogenase/Reductase Family 34C, Member 1²
Retinal Short-Chain Dehydrogenase/Reductase 4² ³		DHRS7A³
RetSDR4¹		EC 1.1.-.-³

External Ids:	HGNC: 21524¹	Entrez Gene: 51635²	Ensembl: ENSG00000100612⁷	OMIM: 612833⁵	UniProtKB: Q9Y394³

Export aliases for DHRS7 gene to outside databases

Previous GC identifers: GC14M058602 GC14M058603 GC14M059681 GC14M040775

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DHRS7:

Short-chain dehydrogenases/reductases (SDRs), such as DHRS7, catalyze the oxidation/reduction of a wide range of

substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 (PubMed 10800688)).(supplied by OMIM, Jun

2009)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000014.8 NC_018925.1 NT_026437.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DHRS7 gene promoter:
TBP POU2F2 (Oct-2.1) Oct-B1 oct-B3 oct-B2 POU2F2 POU2F2C POU2F1 POU2F1a POU2F2B
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DHRS7 promoter sequence

Search SABiosciences Chromatin IP Primers for DHRS7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHRS7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q23.1 Ensembl cytogenetic band: 14q23.1 HGNC cytogenetic band: 14q23.1

DHRS7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHRS7 gene location

GeneLoc information about chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14M060610: view genomic region (about GC identifiers)

Start:	60,610,838 bp from pter	End:	60,636,574 bp from pter
Size:	25,737 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DHRS7_HUMAN, Q9Y394 (See protein sequence)

Recommended Name: Dehydrogenase/reductase SDR family member 7 precursor

Size: 339 amino acids; 38299 Da

Secondary accessions: B2R896 Q9UKU2

Alternative splicing: 2 isoforms: Q9Y394-1 Q9Y394-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DHRS7: NX_Q9Y394

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9Y394

DHRS7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_057113.1

ENSEMBL proteins:

ENSP00000216500 ENSP00000452026 ENSP00000442993 ENSP00000450899 ENSP00000451321

ENSP00000452375 ENSP00000451882

Human Recombinant Protein Products for DHRS7:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: DHRS7 OriGene Custom Protein Services for DHRS7
	GenScript Custom Purified and Recombinant Proteins Services for DHRS7
	Novus Biologicals DHRS7 Protein Novus Biologicals DHRS7 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for DHRS7

DHRS7 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for DHRS7
	GenScript Custom Superior Antibodies Services for DHRS7
	Novus Biologicals DHRS7 Antibodies
	Abcam antibodies for DHRS7
	Uscn Antibodies for DHRS7
	ThermoFisher Antibody for DHRS7

Assay Products for DHRS7:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for DHRS7
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for DHRS7

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DHRS7 for domains About GeneDecksing

4 InterPro domains/families:

IPR020904 Sc_DH/Rdtase_CS

IPR016040 NAD(P)-bd_dom

IPR002347 Glc/ribitol_DH

IPR002198 DH_sc/Rdtase_SDR

Graphical View of Domain Structure for InterPro Entry Q9Y394

ProtoNet protein and cluster: Q9Y394

1 Blocks protein family: IPB002198 Short-chain dehydrogenase/reductase SDR

UniProtKB/Swiss-Prot: DHRS7_HUMAN, Q9Y394

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Enzyme Number (IUBMB): EC 1.1.-.-¹

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0016491	oxidoreductase activity	IEA	--

DHRS7 for ontologies About GeneDecksing

Phenotypes:
3 GenomeRNAi human phenotypes for DHRS7:

G0/1 arrest

Increased G1 DNA content

Synthetic lethal with c-Myc af

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DHRS7

miRNA Products:		OriGene 3'-UTR Clone: DHRS7 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DHRS7
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DHRS7
		SwitchGear 3'UTR luciferase reporter plasmid: DHRS7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DHRS7 (see all 7) OriGene shRNA RFP: DHRS7 OriGene siRNA: DHRS7
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DHRS7
		Sirion Biotech Custom design and validation of potent shRNA sequences against DHRS7

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for DHRS7
			Sirion Biotech Customized adenovirus for overexpression of DHRS7 Sirion Biotech Customized adenovirus for potent knockdown of DHRS7

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DHRS7 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DHRS7 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DHRS7 (NM_015510)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DHRS7
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DHRS7

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DHRS7
		Search LifeMap BioReagents cell lines for DHRS7
		Sirion Biotech Customized stable knockdown cell line services for DHRS7 Sirion Biotech Customized inducible knockdown cell line services for DHRS7 Sirion Biotech Customized stable overexpressing cell line services for DHRS7 Sirion Biotech Customized inducible overexpressing cell line services for DHRS7

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHRS7

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DHRS7

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

4 Interacting proteins for DHRS7 (Q9Y394³ ENSP00000216500⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RICTOR	Q6R327³	I2D: score=1
RPS9	P46781³	I2D: score=1
UBC	ENSP00000344818⁴	STRING: ENSP00000344818
ETV5	ENSP00000306894⁴	STRING: ENSP00000306894

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DHRS7
Search CenterWatch for drugs/clinical trials and news about DHRS7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DHRS7 gene:

NM_016029.2

Unigene Cluster for DHRS7:

Dehydrogenase/reductase (SDR family) member 7

Hs.59719 [show with all ESTs]

Unigene Representative Sequence: BU541074

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000216500(uc001xes.3 uc001xet.3) ENST00000557751 ENST00000536410

ENST00000554101 ENST00000553986 ENST00000557137 ENST00000556502 ENST00000555171

ENST00000557326 ENST00000553328 ENST00000557185

miRNA Products:		OriGene 3'-UTR Clone: DHRS7 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DHRS7
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DHRS7
		SwitchGear 3'UTR luciferase reporter plasmid: DHRS7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DHRS7 (see all 7) OriGene shRNA RFP: DHRS7 OriGene siRNA: DHRS7
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DHRS7
		Sirion Biotech Custom design and validation of potent shRNA sequences against DHRS7

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DHRS7 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DHRS7 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DHRS7 (NM_015510)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DHRS7
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DHRS7

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DHRS7 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat DHRS7
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DHRS7
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHRS7

Additional cDNA sequence:

AF126782.1 AF151844.1 AK313285.1 AL117420.1 AY359031.1 BC000637.2 BC007337.2

11 DOTS entries:

DT.456185 DT.100807010 DT.95186383 DT.120745789 DT.75142986 DT.95186386 DT.75157387 DT.95186380

DT.120745766 DT.120745862 DT.86854156

24/386 AceView cDNA sequences (see all 386):

AI433414 BQ674782 AI253091 BQ640424 AI285472 BI752864 BM055179 AA883522

CR624637 BQ276464 BM695968 BM449453 AL599496 AI697738 BF512645 AI332904

BM466818 AI282366 AI824932 CB135529 AA017652 BG055064 N93481 BQ028664

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DHRS7 (see all 6) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3	^	4a	·	4b	^	5	^	6	^	7a	·	7b	·	7c	^	8	^	9
SP1:							-		-		-				-						-
SP2:															-						-
SP3:															-				-
SP4:
SP5:

ECgene alternative splicing isoforms for DHRS7

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DHRS7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATCTTGCAA

About this image

DHRS7 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Heart

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DHRS7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DHRS7

SOURCE GeneReport for Unigene cluster: Hs.59719

SABiosciences Custom PCR Arrays for DHRS7

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DHRS7 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat DHRS7
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DHRS7
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHRS7

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHRS7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for DHRS7 gene from 7/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	DHRS7¹	dehydrogenase/reductase (SDR family) member 7	71.38(n) 69.54(a)		423527 XM_421423.3 XP_421423.2
lizard (Anolis carolinensis)	Reptilia	DHRS7⁶	--	66(a)	1 ↔ 1	GL343261.1(1170550-1187720)
African clawed frog (Xenopus laevis)	Amphibia	Xl.18967²	Xenopus laevis transcribed sequence with weak similarity more	73.9(n)		BG410026.1
zebrafish (Danio rerio)	Actinopterygii	dhrs7¹	dehydrogenase/reductase (SDR family) member 7	60.14(n) 60.84(a)		751626 NM_001045346.1 NP_001038811.1
fruit fly (Drosophila melanogaster)	Insecta	CG31937¹	CG31937	47.29(n) 37.01(a)		326177 NM_134772.3 NP_608616.2
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G03330¹	Rossmann-fold NAD(P)-binding domain-containing protein	49.28(n) 41.47(a)		821281 NM_111204.4 NP_186983.2
rice (Oryza sativa)	Liliopsida	Os11g0265400¹	hypothetical protein	44.95(n) 36.27(a)		4350245 NM_001074191.1 NP_001067659.1

ENSEMBL Gene Tree for DHRS7 (if available)
TreeFam Gene Tree for DHRS7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DHRS7 gene

SDR9C7² DHRS9² HSD11B2² HSD17B6² HSD17B2² BDH1² RDH8² RDH16²

DHRS7B² HSD17B1² KDSR² DHRS7C² RDH5²

5 SIMAP similar genes for DHRS7 using alignment to 5 protein entries: DHRS7_HUMAN (see all proteins):

DKFZp564H1664 BDH1 DHRS3 DHRS7B DHRS4L2

DHRS7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 14 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs199530426^1,2	C	--	60611059(+)	`TTTTTG/TTCCCC`	1	--	int¹		0	--	--	--	--
rs115003277^1,2	F	--	60611194(+)	`TCTGTC/TCCTTC`	1	--	int¹		1		WA	118
rs191422958^1,2		--	60611249(+)	`ATGAGG/TTGCCA`	1	--	int¹		0	--	--	--	--
rs381237^1,2	C,F,A	--	60611393(-)	`TTGTGC/TTGCTA`	1	--	int¹		8		WA NA CSA EA	369
rs77784211^1,2	F	--	60611455(+)	`ATTTTA/GAAAGG`	1	--	int¹		1		NA	120
rs112492557^1,2	F	--	60611521(+)	`AATCTC/TTTATT`	1	--	ut3¹		1		CSA	6
rs409866^1,2	C,F,O,A,H	--	60611528(-)	`AATAAA/GTAATA`	1	--	ut3¹		22		MN NS EA NA WA CSA	2527
rs439332^1,2	C,F,O,A,H	--	60611585(-)	`TTGTGA/GTTTTA`	1	--	ut3¹		25		MN NS EA NA WA CSA EU	3262
rs399535^1,2	C,F,O,A,H	--	60611648(-)	`AGGGAA/GAAATG`	1	--	ut3¹ trp³		26		EA NA NS WA CSA EU	3871
rs77631725^1,2		--	60611664(+)	`GGCTTG/TAAAAG`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for DHRS7 (60610838 - 60636574 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DHRS7: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DHRS7

DNA2.0 Custom Variant and Variant Library Synthesis for DHRS7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DHRS7 for disorders           About GeneDecksing

OMIM gene information: 612833    OMIM disorders: --

4 diseases for DHRS7:    About MalaCards

retinitis pneumonia tuberculosis mycobacterium tuberculosis

Export disorders for DHRS7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DHRS7 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with DHRS7)

Utopia: connect your pdf to the dynamic
world of online information

Short-chain dehydrogenases/reductases in retina. (PubMed id 10800688)^{1, 2, 3} Haeseleer F. and Palczewski K. (2000)
Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)^{1, 2, 3} Lai C.H....Lin W. (2000)
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)^{1, 3} Persson B.... Oppermann U. (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)^{1, 2} Heilig R.... Weissenbach J. (2003)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)¹ Oshikawa K....Nakayama K.I. (2012)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
A genome-wide meta-analysis of genetic variants associ ated with allergic rhinitis and grass sensitization and their interaction with b irth order. (PubMed id 22036096)¹ Ramasamy A....Jarvis D.L. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 51635	HGNC: 21524	AceView: DHRS7	Ensembl:ENSG00000100612	euGenes: HUgn51635
ECgene: DHRS7	H-InvDB: DHRS7

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DHRS7	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DHRS7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DHRS7 gene:
Search GeneIP for patents involving DHRS7

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for DHRS7
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DHRS7		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DHRS7
	OriGene Protein Over-expression Lysate for DHRS7		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for DHRS7		OriGene 3'-UTR Clone for DHRS7
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DHRS7		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DHRS7
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for DHRS7		OriGene Custom Protein Services for DHRS7
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DHRS7
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DHRS7
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHRS7
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DHRS7
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHRS7
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DHRS7

	GenScript Custom Purified and Recombinant Proteins Services for DHRS7		GenScript cDNA clones with any tag delivered in your preferred vector for DHRS7
	GenScript Custom Assay Services for DHRS7		GenScript Custom Superior Antibodies Services for DHRS7
	GenScript Custom overexpressing Cell Line Services for DHRS7		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in DHRS7 promoter
	Search Chromatin IP Primers for DHRS7
	RT² qPCR Primer Assay in human, mouse, rat DHRS7
	Search GNC Networks for DHRS7
	SABiosciences Custom PCR Arrays for DHRS7

Search Tocris compounds for DHRS7

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	DHRS7 antibodies
	DHRS7 proteins
	DHRS7 lysates

	Antibodies for DHRS7
	See all of Abcam's Antibodies, Kits and Proteins for DHRS7
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

DHRS7 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for DHRS7

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHRS7

	SwitchGear 3'UTR luciferase reporter plasmids for DHRS7
	SwitchGear Promoter luciferase reporter plasmids for DHRS7

ThermoFisher Antibody for DHRS7

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DHRS7

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DHRS7

Sirion Biotech Customized:

	stable knockdown cell line services for DHRS7
	inducible knockdown cell line services for DHRS7
	design and validation of potent shRNA sequences against DHRS7
	adenovirus for potent knockdown of DHRS7
	adenovirus for overexpression of DHRS7
	stable overexpressing cell line services for DHRS7
	inducible overexpressing cell line services for DHRS7

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes DHRS7 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

DHRS7 Gene

dehydrogenase/reductase (SDR family) member 7

Aliases
for DHRS7 gene

Summaries
for DHRS7 gene

Genomic Views
for DHRS7 gene

Proteins
for DHRS7 gene

Protein Domains /
Families
for DHRS7 gene

Function
for DHRS7 gene

Pathways & Interactions
for DHRS7 gene

Drugs & Compounds
for DHRS7 gene

Transcripts
for DHRS7 gene

Expression
for DHRS7 gene

Orthologs
for DHRS7 gene

Paralogs
for DHRS7 gene

Genomic Variants
for DHRS7 gene

Disorders / Diseases
for DHRS7 gene

Publications
for DHRS7 gene

External Searches for DHRS7 gene

Genome Databases showing DHRS7 gene

Other Databases showing DHRS7 gene

Specialized Databases showing DHRS7 gene

Intellectual Property
for DHRS7 gene

Products
for DHRS7 gene

View Random Gene

Advanced Search

Export list of displayed genes

DHRS7 Gene

dehydrogenase/reductase (SDR family) member 7

Aliasesfor DHRS7 gene

Summariesfor DHRS7 gene

Genomic Viewsfor DHRS7 gene

Proteinsfor DHRS7 gene

Protein Domains /Familiesfor DHRS7 gene

Functionfor DHRS7 gene

Pathways & Interactionsfor DHRS7 gene

Drugs & Compoundsfor DHRS7 gene

Transcriptsfor DHRS7 gene

Expression for DHRS7 gene

Orthologsfor DHRS7 gene

Paralogsfor DHRS7 gene

Genomic Variantsfor DHRS7 gene

Disorders / Diseasesfor DHRS7 gene

Publicationsfor DHRS7 gene

External Searches for DHRS7 gene

Genome Databases showing DHRS7 gene

Other Databases showing DHRS7 gene

Specialized Databases showing DHRS7 gene

Intellectual Propertyfor DHRS7 gene

Productsfor DHRS7 gene

View Random Gene

Aliases
for DHRS7 gene

Summaries
for DHRS7 gene

Genomic Views
for DHRS7 gene

Proteins
for DHRS7 gene

Protein Domains /
Families
for DHRS7 gene

Function
for DHRS7 gene

Pathways & Interactions
for DHRS7 gene

Drugs & Compounds
for DHRS7 gene

Transcripts
for DHRS7 gene

Expression
for DHRS7 gene

Orthologs
for DHRS7 gene

Paralogs
for DHRS7 gene

Genomic Variants
for DHRS7 gene

Disorders / Diseases
for DHRS7 gene

Publications
for DHRS7 gene

Intellectual Property
for DHRS7 gene

Products
for DHRS7 gene