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Aliases for DHRS4-AS1 Gene

Subcategory (RNA class) for DHRS4-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for DHRS4-AS1 Gene

  • DHRS4 Antisense RNA 1 2 3 4 5
  • DHRS4 Antisense RNA 1 (Non-Protein Coding) 2 3
  • C14orf167 3 4
  • Chromosome 14 Open Reading Frame 167 2
  • DHRS4 Antisense Gene Protein 1 4
  • AS1DHRS4 3
  • C14orf67 3
  • DHRS4AS1 3
  • PRO1488 3

External Ids for DHRS4-AS1 Gene

Previous HGNC Symbols for DHRS4-AS1 Gene

  • C14orf167

Previous GeneCards Identifiers for DHRS4-AS1 Gene

  • GC14M024408

Summaries for DHRS4-AS1 Gene

GeneCards Summary for DHRS4-AS1 Gene

DHRS4-AS1 (DHRS4 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DHRS4-AS1 Gene

Genomics for DHRS4-AS1 Gene

Regulatory Elements for DHRS4-AS1 Gene

Enhancers for DHRS4-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G023953 1.1 ENCODE 31.2 +34.7 34735 2.0 HDGF PKNOX1 CREB3L1 MLX ZFP64 SIN3A ARID4B DMAP1 ZNF2 YY1 DHRS4 DHRS4-AS1 PABPN1 ENSG00000259321 MDP1 BCL2L2 DHRS4L2
GH14G023939 0.9 ENCODE 29.2 +48.9 48901 0.8 HDAC1 ATF1 ARNT ARID4B DMAP1 RARA TCF12 GATA4 KLF13 THAP11 DHRS4-AS1 DHRS4 LINC00596
GH14G023951 0.8 ENCODE 32.8 +36.9 36903 0.3 CTCF TFAP4 ZNF792 SAP130 TAF1 ARID4B DMAP1 ZNF644 ZNF48 RAD21 DHRS4-AS1 DHRS4 ZFHX2 ZFHX2-AS1 LINC00596
GH14G023140 1.5 FANTOM5 ENCODE dbSUPER 7.4 +846.8 846784 2.9 FOXA2 ZFP64 ARID4B DMAP1 ZNF48 ZNF121 SLC30A9 ZNF143 ZHX2 MXD4 SLC7A8 RNF212B CEBPE ACIN1 SLC22A17 C14orf93 IL25 CMTM5 DHRS4-AS1 RNU6-1138P
GH14G023638 1.3 Ensembl ENCODE 5.7 +348.1 348122 4.8 HNRNPUL1 PKNOX1 FOXA2 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 MYH6 DHRS4-AS1 PIR53509 GC14P023987
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DHRS4-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for DHRS4-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000066804 -61 601 ELF3 PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF48 RAD21 RARA

Genomic Location for DHRS4-AS1 Gene

Chromosome:
14
Start:
23,938,731 bp from pter
End:
23,988,839 bp from pter
Size:
50,109 bases
Orientation:
Minus strand

Genomic View for DHRS4-AS1 Gene

Genes around DHRS4-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DHRS4-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DHRS4-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DHRS4-AS1 Gene

Proteins for DHRS4-AS1 Gene

  • Protein details for DHRS4-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P1J3-DHAS1_HUMAN
    Recommended name:
    Putative uncharacterized protein DHRS4-AS1
    Protein Accession:
    Q9P1J3

    Protein attributes for DHRS4-AS1 Gene

    Size:
    65 amino acids
    Molecular mass:
    7343 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DHRS4-AS1 Gene

Post-translational modifications for DHRS4-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DHRS4-AS1 Gene

Domains & Families for DHRS4-AS1 Gene

Gene Families for DHRS4-AS1 Gene

Protein Domains for DHRS4-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DHRS4-AS1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for DHRS4-AS1 Gene

Function for DHRS4-AS1 Gene

Phenotypes for DHRS4-AS1 Gene

GenomeRNAi human phenotypes for DHRS4-AS1:
genes like me logo Genes that share phenotypes with DHRS4-AS1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DHRS4-AS1 Gene

Localization for DHRS4-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DHRS4-AS1 Gene

Pathways & Interactions for DHRS4-AS1 Gene

SuperPathways for DHRS4-AS1 Gene

No Data Available

Interacting Proteins for DHRS4-AS1 Gene

Gene Ontology (GO) - Biological Process for DHRS4-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DHRS4-AS1 Gene

Transcripts for DHRS4-AS1 Gene

mRNA/cDNA for DHRS4-AS1 Gene

(1) REFSEQ mRNAs :
(13) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DHRS4-AS1 Gene

DHRS4 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DHRS4-AS1 Gene

No ASD Table

Relevant External Links for DHRS4-AS1 Gene

GeneLoc Exon Structure for
DHRS4-AS1
ECgene alternative splicing isoforms for
DHRS4-AS1

Expression for DHRS4-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DHRS4-AS1 Gene

SOURCE GeneReport for Unigene cluster for DHRS4-AS1 Gene:

Hs.569361
genes like me logo Genes that share expression patterns with DHRS4-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DHRS4-AS1 Gene

Orthologs for DHRS4-AS1 Gene

Evolution for DHRS4-AS1 Gene

ENSEMBL:
Gene Tree for DHRS4-AS1 (if available)
TreeFam:
Gene Tree for DHRS4-AS1 (if available)

No data available for Orthologs for DHRS4-AS1 Gene

Paralogs for DHRS4-AS1 Gene

No data available for Paralogs for DHRS4-AS1 Gene

Variants for DHRS4-AS1 Gene

Sequence variations from dbSNP and Humsavar for DHRS4-AS1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000147013 -- 23,954,276(+) CCACG(C/G)CCTCC intron-variant, upstream-variant-2KB
rs1000152177 -- 23,950,929(+) TCTCT(C/G)CTTGG intron-variant
rs1000204968 -- 23,951,094(+) GAAAA(C/G)GATGG intron-variant
rs1000255199 -- 23,941,526(+) CAGTT(C/T)TGAAA intron-variant
rs1000356138 -- 23,945,349(+) AAATT(A/G)GATAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DHRS4-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv1837n100 CNV loss 25217958
dgv1838n100 CNV gain 25217958
dgv36e203 CNV gain+loss 21179565
esv27040 CNV loss 19812545
esv3633790 CNV loss 21293372
esv3633791 CNV gain 21293372
nsv1217 CNV deletion 18451855
nsv1218 CNV insertion 18451855
nsv564046 CNV loss 21841781
nsv89 CNV deletion 15895083
nsv974316 CNV duplication 23825009

Variation tolerance for DHRS4-AS1 Gene

Gene Damage Index Score: 3.07; 50.67% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for DHRS4-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DHRS4-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DHRS4-AS1 Gene

Disorders for DHRS4-AS1 Gene

Relevant External Links for DHRS4-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DHRS4-AS1

No disorders were found for DHRS4-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DHRS4-AS1 Gene

Publications for DHRS4-AS1 Gene

  1. Enhancer RNA-driven looping enhances the transcription of the long noncoding RNA DHRS4-AS1, a controller of the DHRS4 gene cluster. (PMID: 26864944) Yang Y. … Huang D. (Sci Rep 2016) 2 3 64
  2. AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and trans. (PMID: 22891334) Li Q. … Huang D. (Proc. Natl. Acad. Sci. U.S.A. 2012) 2 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for DHRS4-AS1 Gene

Sources for DHRS4-AS1 Gene

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