Aliases for DHRS3 Gene
External Ids for DHRS3 Gene
Previous GeneCards Identifiers for DHRS3 Gene
Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]
GeneCards Summary for DHRS3 Gene
DHRS3 (Dehydrogenase/Reductase (SDR Family) Member 3) is a Protein Coding gene. Diseases associated with DHRS3 include Neuroblastoma. Among its related pathways are Metabolism of xenobiotics by cytochrome P450 and Signaling by Retinoic Acid. GO annotations related to this gene include nucleotide binding and electron carrier activity. An important paralog of this gene is RDH10.
UniProtKB/Swiss-Prot for DHRS3 Gene
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.