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Aliases for DHRS13 Gene

Aliases for DHRS13 Gene

  • Dehydrogenase/Reductase (SDR Family) Member 13 2 3
  • Short Chain Dehydrogenase/Reductase Family 7C Member 5 3 4
  • SDR7C5 3 4
  • Short Chain Dehydrogenase/Reductase Family 7C, Member 5 3
  • Short Chain Dehydrogenase/Reductase Family 7C 2
  • Dehydrogenase/Reductase SDR Family Member 13 3
  • EC 1.1.-.- 4
  • Member 5 2

External Ids for DHRS13 Gene

Previous GeneCards Identifiers for DHRS13 Gene

  • GC17M024249
  • GC17M027224
  • GC17M023433

Summaries for DHRS13 Gene

GeneCards Summary for DHRS13 Gene

DHRS13 (Dehydrogenase/Reductase (SDR Family) Member 13) is a Protein Coding gene. GO annotations related to this gene include oxidoreductase activity. An important paralog of this gene is DHRS12.

UniProtKB/Swiss-Prot for DHRS13 Gene

  • Putative oxidoreductase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DHRS13 Gene

Genomics for DHRS13 Gene

Regulatory Elements for DHRS13 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for DHRS13 Gene

28,897,781 bp from pter
28,903,071 bp from pter
5,291 bases
Minus strand

Genomic View for DHRS13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DHRS13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DHRS13 Gene

Proteins for DHRS13 Gene

  • Protein details for DHRS13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Dehydrogenase/reductase SDR family member 13
    Protein Accession:
    Secondary Accessions:
    • B4DJC5
    • Q96BH7

    Protein attributes for DHRS13 Gene

    377 amino acids
    Molecular mass:
    40849 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DHRS13 Gene


neXtProt entry for DHRS13 Gene

Proteomics data for DHRS13 Gene at MOPED

Post-translational modifications for DHRS13 Gene

  • Ubiquitination at Lys201
  • Modification sites at PhosphoSitePlus

Other Protein References for DHRS13 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for DHRS13 Gene

Domains for DHRS13 Gene

Gene Families for DHRS13 Gene

  • SDRC2 :Short chain dehydrogenase/reductase superfamily / Classical SDR fold cluster 2

Suggested Antigen Peptide Sequences for DHRS13 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q6UX07
  • Belongs to the short-chain dehydrogenases/reductases (SDR) family.
genes like me logo Genes that share domains with DHRS13: view

Function for DHRS13 Gene

Molecular function for DHRS13 Gene

UniProtKB/Swiss-Prot Function:
Putative oxidoreductase.

Enzyme Numbers (IUBMB) for DHRS13 Gene

Gene Ontology (GO) - Molecular Function for DHRS13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity --
GO:0016491 oxidoreductase activity IEA --
GO:0050662 coenzyme binding --
genes like me logo Genes that share ontologies with DHRS13: view

Phenotypes for DHRS13 Gene

GenomeRNAi human phenotypes for DHRS13:
genes like me logo Genes that share phenotypes with DHRS13: view

Animal Model Products

miRNA for DHRS13 Gene

miRTarBase miRNAs that target DHRS13

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DHRS13

In Situ Assay Products

Flow Cytometry Products

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for DHRS13 Gene

Localization for DHRS13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DHRS13 Gene


Subcellular locations from

Jensen Localization Image for DHRS13 Gene COMPARTMENTS Subcellular localization image for DHRS13 gene
Compartment Confidence
extracellular 3
cytosol 1
endoplasmic reticulum 1
lysosome 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for DHRS13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with DHRS13: view

Pathways for DHRS13 Gene

SuperPathways for DHRS13 Gene

No Data Available

Interacting Proteins for DHRS13 Gene

Gene Ontology (GO) - Biological Process for DHRS13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process --
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with DHRS13: view

No data available for Pathways by source for DHRS13 Gene

Transcripts for DHRS13 Gene

mRNA/cDNA for DHRS13 Gene

Unigene Clusters for DHRS13 Gene

Dehydrogenase/reductase (SDR family) member 13:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DHRS13

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DHRS13 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5

Relevant External Links for DHRS13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DHRS13 Gene

mRNA expression in normal human tissues for DHRS13 Gene

mRNA differential expression in normal tissues according to GTEx for DHRS13 Gene

This gene is overexpressed in Whole Blood (13.2).

Protein differential expression in normal tissues for DHRS13 Gene

This gene is overexpressed in Lung (11.4), Retina (10.3), Platelet (8.7), Adrenal (8.6), and Breast (7.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DHRS13 Gene

SOURCE GeneReport for Unigene cluster for DHRS13 Gene Hs.631760

genes like me logo Genes that share expressions with DHRS13: view

Expression partners for DHRS13 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for DHRS13 Gene

Orthologs for DHRS13 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DHRS13 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia DHRS13 35
  • 87.2 (n)
  • 89.07 (a)
DHRS13 36
  • 89 (a)
(Canis familiaris)
Mammalia DHRS13 35
  • 88.8 (n)
  • 88.15 (a)
-- 36
  • 36 (a)
(Mus musculus)
Mammalia Dhrs13 35
  • 84.45 (n)
  • 84.92 (a)
Dhrs13 16
Dhrs13 36
  • 84 (a)
(Pan troglodytes)
Mammalia DHRS13 35
  • 99.66 (n)
  • 100 (a)
DHRS13 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1305508 35
  • 81.14 (n)
  • 80.43 (a)
(Monodelphis domestica)
Mammalia DHRS13 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia DHRS13 36
  • 76 (a)
(Gallus gallus)
Aves DHRS13 36
  • 50 (a)
(Anolis carolinensis)
Reptilia DHRS13 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia dhrs13 35
  • 60.4 (n)
  • 58.39 (a)
(Danio rerio)
Actinopterygii dhrs13a.3 35
  • 55.78 (n)
  • 54.88 (a)
CU638740.1 36
  • 43 (a)
DHRS13 (5 of 7) 36
  • 41 (a)
dhrs13a.1 36
  • 51 (a)
dhrs13a.2 36
  • 49 (a)
dhrs13a.3 36
  • 53 (a)
dhrs13b 36
  • 47 (a)
dhrs13l1 36
  • 50 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG31235 36
  • 28 (a)
(Caenorhabditis elegans)
Secernentea dhs-22 36
  • 32 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ENV9 36
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 22 (a)
Species with no ortholog for DHRS13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DHRS13 Gene

Gene Tree for DHRS13 (if available)
Gene Tree for DHRS13 (if available)

Paralogs for DHRS13 Gene

Paralogs for DHRS13 Gene

Selected SIMAP similar genes for DHRS13 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with DHRS13: view

Variants for DHRS13 Gene

Sequence variations from dbSNP and Humsavar for DHRS13 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs2277666 - 28,901,100(+) CCTGC(C/T)GCCAG missense, reference, nc-transcript-variant
rs4795474 -- 28,901,180(+) ACCAC(A/G)CGGCT reference, synonymous-codon, nc-transcript-variant
rs28523716 -- 28,900,587(+) GTCTT(A/T)GTTTT intron-variant
rs34200761 -- 28,901,276(+) GCCTC(A/G)CGGGT synonymous-codon, reference, nc-transcript-variant
rs34370083 -- 28,900,296(+) GTGCT(-/G)GGGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DHRS13 Gene

Variant ID Type Subtype PubMed ID
nsv457719 CNV Loss 19166990

Relevant External Links for DHRS13 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DHRS13 Gene

Disorders for DHRS13 Gene

No disorders were found for DHRS13 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for DHRS13 Gene

Publications for DHRS13 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PMID: 19027726) Persson B. … Oppermann U. (Chem. Biol. Interact. 2009) 2 3 4
  3. Defining the membrane proteome of NK cells. (PMID: 19946888) Ghosh D. … Wilkins J.A. (J Mass Spectrom 2010) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3

Products for DHRS13 Gene

Sources for DHRS13 Gene

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