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Aliases for DHRS13 Gene

Aliases for DHRS13 Gene

  • Dehydrogenase/Reductase (SDR Family) Member 13 2 3 5
  • Short Chain Dehydrogenase/Reductase Family 7C Member 5 3 4
  • SDR7C5 3 4
  • Short Chain Dehydrogenase/Reductase Family 7C, Member 5 3
  • Short Chain Dehydrogenase/Reductase Family 7C 2
  • EC 1.1.-.- 4
  • Member 5 2

External Ids for DHRS13 Gene

Previous GeneCards Identifiers for DHRS13 Gene

  • GC17M024249
  • GC17M027224
  • GC17M023433

Summaries for DHRS13 Gene

GeneCards Summary for DHRS13 Gene

DHRS13 (Dehydrogenase/Reductase (SDR Family) Member 13) is a Protein Coding gene. GO annotations related to this gene include oxidoreductase activity and coenzyme binding. An important paralog of this gene is RDH14.

UniProtKB/Swiss-Prot for DHRS13 Gene

  • Putative oxidoreductase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DHRS13 Gene

Genomics for DHRS13 Gene

Regulatory Elements for DHRS13 Gene

Enhancers for DHRS13 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around DHRS13 on UCSC Golden Path with GeneCards custom track

Promoters for DHRS13 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around DHRS13 on UCSC Golden Path with GeneCards custom track

Genomic Location for DHRS13 Gene

28,897,781 bp from pter
28,903,071 bp from pter
5,291 bases
Minus strand

Genomic View for DHRS13 Gene

Genes around DHRS13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DHRS13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DHRS13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DHRS13 Gene

Proteins for DHRS13 Gene

  • Protein details for DHRS13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Dehydrogenase/reductase SDR family member 13
    Protein Accession:
    Secondary Accessions:
    • B4DJC5
    • Q96BH7

    Protein attributes for DHRS13 Gene

    377 amino acids
    Molecular mass:
    40849 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DHRS13 Gene


neXtProt entry for DHRS13 Gene

Proteomics data for DHRS13 Gene at MOPED

Post-translational modifications for DHRS13 Gene

  • Ubiquitination at Lys 201
  • Modification sites at PhosphoSitePlus

Other Protein References for DHRS13 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DHRS13 Gene

Domains & Families for DHRS13 Gene

Gene Families for DHRS13 Gene

Suggested Antigen Peptide Sequences for DHRS13 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Belongs to the short-chain dehydrogenases/reductases (SDR) family.
genes like me logo Genes that share domains with DHRS13: view

Function for DHRS13 Gene

Molecular function for DHRS13 Gene

UniProtKB/Swiss-Prot Function:
Putative oxidoreductase.

Enzyme Numbers (IUBMB) for DHRS13 Gene

genes like me logo Genes that share phenotypes with DHRS13: view

Animal Model Products

miRNA for DHRS13 Gene

No data available for Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DHRS13 Gene

Localization for DHRS13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DHRS13 Gene


Subcellular locations from

Jensen Localization Image for DHRS13 Gene COMPARTMENTS Subcellular localization image for DHRS13 gene
Compartment Confidence
extracellular 4
cytosol 2
endoplasmic reticulum 1
lysosome 1
mitochondrion 1
peroxisome 1
plasma membrane 1
vacuole 1

No data available for Gene Ontology (GO) - Cellular Components for DHRS13 Gene

Pathways & Interactions for DHRS13 Gene

SuperPathways for DHRS13 Gene

No Data Available

Interacting Proteins for DHRS13 Gene

Gene Ontology (GO) - Biological Process for DHRS13 Gene


No data available for Pathways by source and SIGNOR curated interactions for DHRS13 Gene

Drugs & Compounds for DHRS13 Gene

No Compound Related Data Available

Transcripts for DHRS13 Gene

Unigene Clusters for DHRS13 Gene

Dehydrogenase/reductase (SDR family) member 13:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DHRS13 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5

Relevant External Links for DHRS13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DHRS13 Gene

mRNA expression in normal human tissues for DHRS13 Gene

mRNA differential expression in normal tissues according to GTEx for DHRS13 Gene

This gene is overexpressed in Whole Blood (x13.2).

Protein differential expression in normal tissues from HIPED for DHRS13 Gene

This gene is overexpressed in Lung (11.4), Retina (10.3), Platelet (8.7), Adrenal (8.6), and Breast (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for DHRS13 Gene

SOURCE GeneReport for Unigene cluster for DHRS13 Gene Hs.631760

genes like me logo Genes that share expression patterns with DHRS13: view

Protein tissue co-expression partners for DHRS13 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for DHRS13 Gene

Orthologs for DHRS13 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DHRS13 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia DHRS13 35
  • 87.2 (n)
  • 89.07 (a)
DHRS13 36
  • 89 (a)
(Canis familiaris)
Mammalia DHRS13 35
  • 88.8 (n)
  • 88.15 (a)
-- 36
  • 36 (a)
(Mus musculus)
Mammalia Dhrs13 35
  • 84.45 (n)
  • 84.92 (a)
Dhrs13 16
Dhrs13 36
  • 84 (a)
(Pan troglodytes)
Mammalia DHRS13 35
  • 99.66 (n)
  • 100 (a)
DHRS13 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1305508 35
  • 81.14 (n)
  • 80.43 (a)
(Monodelphis domestica)
Mammalia DHRS13 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia DHRS13 36
  • 76 (a)
(Gallus gallus)
Aves DHRS13 36
  • 50 (a)
(Anolis carolinensis)
Reptilia DHRS13 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia dhrs13 35
  • 60.4 (n)
  • 58.39 (a)
(Danio rerio)
Actinopterygii dhrs13a.3 35
  • 55.78 (n)
  • 54.88 (a)
CU638740.1 36
  • 43 (a)
DHRS13 (5 of 7) 36
  • 41 (a)
dhrs13a.1 36
  • 51 (a)
dhrs13a.2 36
  • 49 (a)
dhrs13a.3 36
  • 53 (a)
dhrs13b 36
  • 47 (a)
dhrs13l1 36
  • 50 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG31235 36
  • 28 (a)
(Caenorhabditis elegans)
Secernentea dhs-22 36
  • 32 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ENV9 36
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 22 (a)
Species with no ortholog for DHRS13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DHRS13 Gene

Gene Tree for DHRS13 (if available)
Gene Tree for DHRS13 (if available)

Paralogs for DHRS13 Gene

Paralogs for DHRS13 Gene

(4) SIMAP similar genes for DHRS13 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with DHRS13: view

Variants for DHRS13 Gene

Sequence variations from dbSNP and Humsavar for DHRS13 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs2277666 - 28,901,100(+) CCTGC(C/T)GCCAG reference, missense
VAR_037349 -
rs4795474 -- 28,901,180(+) ACCAC(A/G)CGGCT reference, synonymous-codon
rs28523716 -- 28,900,587(+) GTCTT(A/T)GTTTT intron-variant
rs34651323 -- 28,904,737(+) TCTAT(-/C)CCTAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for DHRS13 Gene

Variant ID Type Subtype PubMed ID
nsv457719 CNV Loss 19166990

Variation tolerance for DHRS13 Gene

Residual Variation Intolerance Score: 74.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.82; 34.22% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for DHRS13 Gene

Disorders for DHRS13 Gene

Relevant External Links for DHRS13

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for DHRS13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DHRS13 Gene

Publications for DHRS13 Gene

  1. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PMID: 19027726) Persson B. … Oppermann U. (Chem. Biol. Interact. 2009) 2 3 4 67
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. Defining the membrane proteome of NK cells. (PMID: 19946888) Ghosh D. … Wilkins J.A. (J Mass Spectrom 2010) 3

Products for DHRS13 Gene

Sources for DHRS13 Gene