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Aliases for DHFRP1 Gene

Aliases for DHFRP1 Gene

  • Dihydrofolate Reductase Pseudogene 1 2 3

External Ids for DHFRP1 Gene

Previous GeneCards Identifiers for DHFRP1 Gene

  • GC18U990010
  • GC02P082937
  • GC18M022002
  • GC18M023747

Summaries for DHFRP1 Gene

GeneCards Summary for DHFRP1 Gene

DHFRP1 (Dihydrofolate Reductase Pseudogene 1) is a Pseudogene. Among its related pathways are E2F transcription factor network. GO annotations related to this gene include mRNA binding and NADP binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DHFRP1 Gene

Genomics for DHFRP1 Gene

Genomic Location for DHFRP1 Gene

Start:
26,167,862 bp from pter
End:
26,171,357 bp from pter
Size:
3,496 bases
Orientation:
Minus strand

Genomic View for DHFRP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DHFRP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DHFRP1 Gene

No data available for Regulatory Elements for DHFRP1 Gene

Proteins for DHFRP1 Gene

Post-translational modifications for DHFRP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DHFRP1 Gene

Domains for DHFRP1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for DHFRP1 Gene

Function for DHFRP1 Gene

Molecular function for DHFRP1 Gene

GENATLAS Biochemistry:
dihydrofolate reductase,pseudogene 1

Gene Ontology (GO) - Molecular Function for DHFRP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003729 mRNA binding IDA 21876184
GO:0004146 dihydrofolate reductase activity NAS 6687716
GO:0008144 drug binding IDA 12096917
GO:0050661 NADP binding IEA --
genes like me logo Genes that share ontologies with DHFRP1: view

miRNA for DHFRP1 Gene

miRTarBase miRNAs that target DHFRP1

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for DHFRP1 Gene

Localization for DHFRP1 Gene

Gene Ontology (GO) - Cellular Components for DHFRP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005654 nucleoplasm TAS --
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with DHFRP1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for DHFRP1 Gene

Pathways for DHFRP1 Gene

genes like me logo Genes that share pathways with DHFRP1: view

Pathways by source for DHFRP1 Gene

1 BioSystems pathway for DHFRP1 Gene

Interacting Proteins for DHFRP1 Gene

Gene Ontology (GO) - Biological Process for DHFRP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000082 G1/S transition of mitotic cell cycle TAS --
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle TAS --
GO:0000278 mitotic cell cycle TAS --
GO:0006545 glycine biosynthetic process IEA --
GO:0006730 one-carbon metabolic process IEA --
genes like me logo Genes that share ontologies with DHFRP1: view

Compounds for DHFRP1 Gene

(2) ApexBio Compounds for DHFRP1 Gene

Compound Action Cas Number
Methotrexate "Folate antagonist,inhibits DFHR" [1959-5-2]
Pralatrexate "Antifolate,a folate analog" [146464-95-1]
genes like me logo Genes that share compounds with DHFRP1: view

Transcripts for DHFRP1 Gene

mRNA/cDNA for DHFRP1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for DHFRP1 Gene

No ASD Table

Relevant External Links for DHFRP1 Gene

GeneLoc Exon Structure for
DHFRP1
ECgene alternative splicing isoforms for
DHFRP1

Expression for DHFRP1 Gene

mRNA expression in normal human tissues for DHFRP1 Gene

genes like me logo Genes that share expressions with DHFRP1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for DHFRP1 Gene

Orthologs for DHFRP1 Gene

Evolution for DHFRP1 Gene

ENSEMBL:
Gene Tree for DHFRP1 (if available)
TreeFam:
Gene Tree for DHFRP1 (if available)

No data available for Orthologs for DHFRP1 Gene

Paralogs for DHFRP1 Gene

No data available for Paralogs for DHFRP1 Gene

Variants for DHFRP1 Gene

Relevant External Links for DHFRP1 Gene

HapMap Linkage Disequilibrium report
DHFRP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for DHFRP1 Gene

Disorders for DHFRP1 Gene

No disorders were found for DHFRP1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for DHFRP1 Gene

Publications for DHFRP1 Gene

  1. A human dihydrofolate reductase pseudogene and its relationship to the multiple forms of specific messenger RNA. (PMID: 6306253) Masters J.N. … Attardi G. (J. Mol. Biol. 1983) 2 3
  2. The functional human dihydrofolate reductase gene. (PMID: 6323448) Chen M.-J. … Nienhuis A.W. (J. Biol. Chem. 1984) 3
  3. The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase. (PMID: 6687716) Masters J.N. … Attardi G. (Gene 1983) 3
  4. Intronless human dihydrofolate reductase genes are derived from processed RNA molecules. (PMID: 6961421) Chen M.J. … Nienhuis A.W. (Proc. Natl. Acad. Sci. U.S.A. 1982) 3
  5. Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers. (PMID: 7890613) Lewis W.S. … Blakley R.L. (J. Biol. Chem. 1995) 3

Products for DHFRP1 Gene

Sources for DHFRP1 Gene

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