Aliases for DHFRL1 Gene
External Ids for DHFRL1 Gene
Previous HGNC Symbols for DHFRL1 Gene
Previous GeneCards Identifiers for DHFRL1 Gene
GeneCards Summary for DHFRL1 Gene
DHFRL1 (Dihydrofolate Reductase-Like 1) is a Protein Coding gene. Diseases associated with DHFRL1 include intrinsic factor deficiency and methylmalonic aciduria and homocystinuria type cblg. Among its related pathways are Disease and Metabolism. GO annotations related to this gene include mRNA binding and dihydrofolate reductase activity. An important paralog of this gene is DHFR.
UniProtKB/Swiss-Prot for DHFRL1 Gene
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.