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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DHDH Gene

protein-coding   GIFtS: 56
GCID: GC19P049436

Dihydrodiol Dehydrogenase (Dimeric)

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dihydrodiol Dehydrogenase (Dimeric)1 2     Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase2
2DD2 3     EC 1.1.1.1793
D-Xylose 1-Dehydrogenase2 3     EC 1.3.1.203
D-Xylose-NADP Dehydrogenase2 3     Hum2DD3
3-Deoxyglucosone Reductase2     Dimeric Dihydrodiol Dehydrogenase3
HUM2DD2     

External Ids:    HGNC: 178871   Entrez Gene: 272942   Ensembl: ENSG000001048087   OMIM: 6063775   UniProtKB: Q9UQ103   

Export aliases for DHDH gene to outside databases

Previous GC identifers: GC19P050095 GC19P049805 GC19P054112 GC19P054128 GC19P045813


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DHDH Gene:
This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple
forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze
the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme
is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high
substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. (provided by
RefSeq, Jul 2008)

GeneCards Summary for DHDH Gene: 
DHDH (dihydrodiol dehydrogenase (dimeric)) is a protein-coding gene. Diseases associated with DHDH include vaccinia, and lung adenocarcinoma, and among its related super-pathways are Chemical carcinogenesis and Ascorbate and aldarate metabolism. GO annotations related to this gene include trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity and nucleotide binding.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DHDH gene promoter:
         ER-alpha   NRSF form 1   STAT5A   AP-4   Nkx5-1   NRSF form 2   C/EBPalpha   AREB6   COMP1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDHDH promoter sequence
   Search SABiosciences Chromatin IP Primers for DHDH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHDH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.3   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.3

DHDH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DHDH gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P049436:  view genomic region     (about GC identifiers)

Start:
49,436,939 bp from pter      End:
49,448,226 bp from pter
Size:
11,288 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DHDH_HUMAN, Q9UQ10 (See protein sequence)
Recommended Name: Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase  
Size: 334 amino acids; 36382 Da
Subunit: Homodimer

Explore the universe of human proteins at neXtProt for DHDH: NX_Q9UQ10

Explore proteomics data for DHDH at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UQ10

  • DHDH Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DHDH Protein Expression
    REFSEQ proteins: NP_055290.1  
    ENSEMBL proteins: 
     ENSP00000221403   ENSP00000428935   ENSP00000428672   ENSP00000430360  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR000683 Oxidoreductase_N
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q9UQ10

    ProtoNet protein and cluster: Q9UQ10

    1 Blocks protein domain: IPB000683 Oxidoreductase

    UniProtKB/Swiss-Prot: DHDH_HUMAN, Q9UQ10
    Similarity: Belongs to the Gfo/Idh/MocA family


    DHDH for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DHDH_HUMAN, Q9UQ10
    Catalytic activity: Trans-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + NADPH
    Catalytic activity: D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH

         Enzyme Numbers (IUBMB): EC 1.3.1.201 EC 1.1.1.1791

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008746NAD(P)+ transhydrogenase activity TAS10477285
    GO:0009055electron carrier activity TAS10477285
    GO:0016491oxidoreductase activity ----
    GO:0047115trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity IEA--
    GO:0047837D-xylose 1-dehydrogenase (NADP+) activity IEA--
         
    DHDH for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DHDH:
     Nuclear pre-40S maturation def 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DHDH 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DHDH

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DHDH 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DHDH About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Drug metabolism - cytochrome P450
    Metabolism of xenobiotics by cytochrome P4500.77
    2Glucuronidation
    Pentose and glucuronate interconversions0.61

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2         Kegg Pathways  (Kegg details for DHDH):
        Pentose and glucuronate interconversions
    Metabolism of xenobiotics by cytochrome P450


    DHDH for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DHDH

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/8 Interacting proteins for DHDH (ENSP000002214034) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AKR1B1ENSP000002859304STRING: ENSP00000285930
    CYP1A1ENSP000003690504STRING: ENSP00000369050
    CYP2B6ENSP000003246484STRING: ENSP00000324648
    EPHX1ENSP000002721674STRING: ENSP00000272167
    CYP1A2ENSP000003420074STRING: ENSP00000342007
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS10477285
    GO:0042843D-xylose catabolic process IEA--

    DHDH for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    DHDH for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DHDH

    6 HMDB Compounds for DHDH    About this table
    CompoundSynonyms CAS #PubMed Ids
    D-Xylono-1,5-lactoneD-Xylonolactone (see all 2)----
    D-Xylosed-Xylose (see all 8)58-86-6--
    NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--
    NADPH2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide (see all 23)53-57-6--
    Pyrocatechol1,2-Dihydroxybenzene (see all 20)120-80-9--
    trans-1,2-Dihydrobenzene-1,2-diolArene diol (see all 7)103302-38-1--

    10/28 Novoseek inferred chemical compound relationships for DHDH gene (see all 28)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    3alpha-hydroxysteroid 92.9 24 1639345 (2), 10619355 (2), 7735258 (2), 7948008 (2) (see all 17)
    naphthalene-1,2-dihydrodiol 87.5 2 9884310 (1)
    chlordecone 84 1 7789999 (1)
    nadp+ 74.9 1 1394622 (1)
    dicoumarol 71.8 1 1722672 (1)
    1,2-naphthoquinone 71.5 2 9109344 (1), 9884310 (1)
    hydrocarbons 70 13 9973208 (2), 12579257 (1), 11752800 (1), 12204825 (1) (see all 12)
    ethacrynic acid 69.7 3 7515059 (1), 7488239 (1), 9406235 (1)
    o-quinone 67.3 1 11453732 (1)
    3-deoxyglucosone 63.6 6 1953687 (3), 8274014 (2)

    Search CenterWatch for drugs/clinical trials and news about DHDH

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DHDH gene: 
    NM_014475.3  

    Unigene Cluster for DHDH:

    Dihydrodiol dehydrogenase (dimeric)
    Hs.631555  [show with all ESTs]
    Unigene Representative Sequence: BM454993
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000221403(uc002ple.1) ENST00000523250 ENST00000522614 ENST00000520557

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DHDH
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHDH

    Additional mRNA sequence: 

    AB021933.1 BC032730.1 

    3 DOTS entries:

    DT.40129584  DT.40126733  DT.92417156 

    3 AceView cDNA sequences:

    AB021933 NM_014475 BC032730 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DHDH expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTTATGAGG
    DHDH Expression
    About this image


    See DHDH Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DHDH

    SOURCE GeneReport for Unigene cluster: Hs.631555

    UniProtKB/Swiss-Prot: DHDH_HUMAN, Q9UQ10
    Tissue specificity: Small intestine

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DHDH gene from 5/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dhdh1 , 5 dihydrodiol dehydrogenase (dimeric)1, 5 78.58(n)1
    78.98(a)1
      7 (29.32 cM)5
    717551  NM_027903.31  NP_082179.11 
     454729565 
    chicken
    (Gallus gallus)
    Aves DHDH6
    dihydrodiol dehydrogenase (dimeric)
    33(a)
    1 ↔ 1
    JH376330.1(21-3262)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    51(a)
    51(a)
    (see all 3)
    many → 1
    many → 1
    (see all 3)
    GL343355.1(469329-482337)
    GL343355.1(491364-497715)
    zebrafish
    (Danio rerio)
    Actinopterygii BQ260196.12   -- 78.65(n)    BQ260196.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG36091 , 3 CG36091 42(a)
    (best of 3)3
    53.6(n)1
    43.47(a)1
      22E13
    334211  NM_001201755.11  NP_001188684.11 


    ENSEMBL Gene Tree for DHDH (if available)
    TreeFam Gene Tree for DHDH (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/386 SNPs in DHDH are shown (see all 386)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs72521591,2
    C,F,H--49434945(+) ccctgC/Tcttga 1 -- us2k16Minor allele frequency- T:0.02NS EA WA 538
    rs1812070091,2
    --49435102(+) TGGGCA/GTGGTG 1 -- us2k10--------
    rs1865234971,2
    --49435150(+) GCAGGC/TGGATC 1 -- us2k10--------
    rs1898014051,2
    --49435263(+) CCCAGC/TTACTC 1 -- us2k10--------
    rs1495461571,2
    --49435277(+) AGGCTC/GAGGTA 1 -- us2k10--------
    rs1133840821,2
    C,F--49435365(+) TGACAG/CAGCGA 1 -- us2k12Minor allele frequency- C:0.04CSA WA 120
    rs726262251,2
    C--49435406(+) CAACAG/ACAACA 1 -- us2k15Minor allele frequency- A:0.35WA CSA NA EA 361
    rs1431218611,2
    --49435449(+) TTGTAA/GTCCCA 1 -- us2k10--------
    rs1823272251,2
    --49435476(+) AGGCAA/GGCAAA 1 -- us2k10--------
    rs1482395941,2
    C--49435484(+) AAATCA/GCAAGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DHDH (49436939 - 49448226 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for DHDH:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv518164CNV Loss19592680
    nsv833855CNV Loss17160897
    nsv833857CNV Loss17160897
    nsv833856CNV Loss17160897
    nsv912248CNV Loss21882294
    nsv521890CNV Gain19592680
    nsv9739CNV Gain+Loss18304495


    Human Gene Mutation Database (HGMD): DHDH
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DHDH
    DNA2.0 Custom Variant and Variant Library Synthesis for DHDH

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606377    OMIM disorders: --

    17 diseases for DHDH:    About MalaCards
    vaccinia    lung adenocarcinoma    esophageal squamous cell carcinoma    cytochrome p450
    pneumonia    hypoxia    lung cancer    cervical cancer
    esophagitis    adenocarcinoma    squamous cell carcinoma    cervicitis
    colon cancer    gastric cancer    hepatocellular carcinoma    ovarian cancer
    hepatitis


    DHDH for disorders           About GeneDecksing

    8 Novoseek inferred disease relationships for DHDH gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    ovarian carcinoma 52.6 3 17661040 (1), 11842089 (1), 15138708 (1)
    nsclc 42.3 6 11289154 (2), 17266043 (1), 11956619 (1)
    cancer lung 24 2 17163506 (2)
    cancer 6.31 1 18214064 (1)
    tumors 5.19 2 17163506 (1), 15138708 (1)
    carcinoma squamous cell 0 3 15197778 (2), 16361083 (1)
    adenocarcinoma 0 2 16886619 (1), 11925926 (1)
    carcinoma 0 1 17009030 (1)

    Genetic Association Database (GAD): DHDH
    Human Genome Epidemiology (HuGE) Navigator: DHDH (5 documents)

    Export disorders for DHDH gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DHDH gene, integrated from 9 sources (see all 97):
    (articles sorted by number of sources associating them with DHDH)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and sequencing of the cDNA species for mammalian dimeric dihydrodiol dehydrogenases. (PubMed id 10477285)1, 2, 3, 9 Arimitsu E.... Hara A. (1999)
    2. Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (2010)
    3. PTEN identified as important risk factor of chronic o bstructive pulmonary disease. (PubMed id 19625176)1, 4 Hosgood H.D....Lan Q. (2009)
    4. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1, 4 Shen M....Lan Q. (2009)
    5. Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (2009)
    6. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1, 4 Hosgood H.D....Lan Q. (2008)
    7. Identity of dimeric dihydrodiol dehydrogenase as NADP(+)-dependent D-xylose dehydrogenase in pig liver. (PubMed id 11306093)1, 9 Aoki S....Hara A. (2001)
    8. Roles of His-79 and Tyr-180 of D-xylose/dihydrodiol dehydrogenase in catalytic function. (PubMed id 11097839)1, 9 Asada Y....Hara A. (2000)
    9. Overexpression of dihydrodiol dehydrogenase as a prognostic marker in resected gastric cancer patients. (PubMed id 18600452)1, 9 Chang H.C....Fang H.Y. (2009)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27294 HGNC: 17887 AceView: DHDH Ensembl:ENSG00000104808 euGenes: HUgn27294
    ECgene: DHDH Kegg: 27294 H-InvDB: DHDH

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DHDH Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DHDH gene:
    Search GeneIP for patents involving DHDH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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