DHDDS Gene
protein-coding GIFtS: 53
GCID: GC01P026758
|
|
dehydrodolichyl diphosphate synthase
| |
Aliases
for DHDDS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Dehydrodolichyl Diphosphate Synthase1 2 | | RP592 | | HDS1 2 3 5 | | Cis-IPTase3 | | DS1 2 | | Cis-Isoprenyltransferase1 | | Dedol-PP Synthase2 3 | | Cis-Prenyl Transferase2 | | Epididymis Tissue Protein Li 189m2 3 | | Cis-IPTase3 | | CIT2 3 | | Cis-Isoprenyltransferase1 | | FLJ131021 | | EC 2.5.1.-3 | | CPT2 | | |
Export aliases for DHDDS gene to outside databasesPrevious GC identifers: GC01P025991 GC01P026363 GC01P026442 GC01P026631 GC01P025013 |
Summaries
for DHDDS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DHDDS:
The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol,a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene areassociated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoformshave been described for this gene. (provided by RefSeq, Aug 2011)
UniProtKB/Swiss-Prot: DHDDS_HUMAN, Q86SQ9Function: Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosylcarrier-lipid required for the biosynthesis of several classes of glycoprotein
Gene Wiki entry for DHDDS
|
Genomic Views
for DHDDS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DHDDS gene promoter:
Sp1 ARP-1 c-Myb Nkx2-5
Other transcription factors
Search SABiosciences Chromatin IP Primers for DHDDS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHDDS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.11 Ensembl cytogenetic band: 1p36.11 HGNC cytogenetic band: 1p35.3DHDDS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P026758: view genomic region
(about GC identifiers)
Start:
|
26,758,773 bp from pter |
End:
|
26,797,797 bp from pter |
Size:
|
39,025 bases |
Orientation:
|
plus strand |
|
Proteins
for DHDDS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DHDDS_HUMAN, Q86SQ9 (See
protein sequence)Recommended Name: Dehydrodolichyl diphosphate synthase Size: 333 amino acids; 38657 Da
Subunit: Interacts with NUS1/NgBR, the interaction is required for efficient activity. Interacts with NPC2
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Note=colocalizes with calnexin
Secondary accessions: B7Z4B9 B7ZB20 D3DPK7 D3DPK8 D3DPK9 E9KL43 Q5T0A4 Q8NE90 Q9BTG5 Q9BTK3 Q9H905Alternative splicing: 4 isoforms: Q86SQ9-1 Q86SQ9-2 Q86SQ9-3 Q86SQ9-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DHDDS: NX_Q86SQ9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86SQ9
DHDDS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001230493.1 NP_001230494.1 NP_079163.2 NP_995583.1
ENSEMBL proteins: ENSP00000403529 ENSP00000399177 ENSP00000434984 ENSP00000236342 ENSP00000434219 ENSP00000363300 ENSP00000353104 ENSP00000436119 ENSP00000436764 ENSP00000434185 ENSP00000431407 ENSP00000433976 ENSP00000405604 ENSP00000433491 ENSP00000397584 ENSP00000399781 ENSP00000393961
Human Recombinant Protein Products for DHDDS:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005789 | endoplasmic reticulum membrane |
IEA | -- |
DHDDS for ontologies About GeneDecksing
DHDDS Antibody Products:
Assay Products for DHDDS: |
Protein
Domains /
Families
for DHDDS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DHDDS for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86SQ9ProtoNet protein and cluster: Q86SQ9 1 Blocks protein family: IPB001441 Di-trans-poly-cis-decaprenylcistransferase
UniProtKB/Swiss-Prot: DHDDS_HUMAN, Q86SQ9Similarity: Belongs to the UPP synthase family |
Function
for DHDDS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: DHDDS_HUMAN, Q86SQ9Function: Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosylcarrier-lipid required for the biosynthesis of several classes of glycoprotein Enzyme Number (IUBMB): EC 2.5.1.-1
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | 15110773 | | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups |
IEA | -- |
DHDDS for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DHDDS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DHDDS (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): DHDDS (NM_024887) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DHDDS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DHDDS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHDDS |
|
Pathways & Interactions
for DHDDS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | dolichol and dolichyl phosphate biosynthesis | | | 2 | superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for DHDDS
1 
Kegg Pathway (Kegg details for DHDDS):
UniProtKB/Swiss-Prot: DHDDS_HUMAN, Q86SQ9Pathway: Protein modification; protein glycosylation
DHDDS for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DHDDS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/38 Interacting proteins for DHDDS (Q86SQ93 ENSP000003531044) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006486 | protein glycosylation |
IEA | -- |
DHDDS for ontologies About GeneDecksing
|
Drugs & Compounds
for DHDDS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DHDDS
1 HMDB Compound for DHDDS About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Undecaprenyl diphosphate | Diphosphoric acid mono(3,7,11,15,19,23,27,31,35,39,43-undecamethyl-2,6,10,14,18,22,26,30,34,38,42-tetratetracontaundecaenyl) ester (see all 8) | 23-13-2 | -- |
Search CenterWatch for drugs/clinical trials and news about DHDDS
|
Transcripts
for DHDDS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DHDDS gene (4 alternative transcripts): NM_001243564.1 NM_001243565.1 NM_024887.3 NM_205861.2 Unigene Cluster for DHDDS: Dehydrodolichyl diphosphate synthase Hs.369385 [show with all ESTs]Unigene Representative Sequence: BX64850718/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25): ENST00000434391(uc001bmk.3 uc001bml.3 uc001bmn.3 uc010ofd.2 uc001bmm.3)
ENST00000427245 ENST00000527611 ENST00000374186 ENST00000525682 ENST00000236342
ENST00000526219 ENST00000374185 ENST00000487944 ENST00000360009 ENST00000533087
ENST00000531312 ENST00000525165 ENST00000525326 ENST00000525546 ENST00000528557
ENST00000526278 ENST00000436153
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DHDDS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DHDDS (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): DHDDS (NM_024887) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DHDDS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DHDDS |
Additional cDNA sequence: AB090852.1 AK023164.1 AK297134.1 AK308187.1 AK316485.1 BC003643.2 BC004117.2 BC034152.1 BX648507.1 GU727641.1 14 DOTS entries: DT.99948354 DT.91758707 DT.97764546 DT.440354 DT.91758706 DT.95069950 DT.100710474 DT.97826366 DT.91758705 DT.97793209 DT.121445892 DT.121445909 DT.40264123 DT.40305720 24/181 AceView cDNA sequences (see all 181): BQ438280 CK822374 AI694618 AI871602 BM352399 BF684863 BU617050 BC003643 AL701938 NM_205861 BM693963 BF062692 BM551407 AW630743 NM_024887 AA809336 BQ184436 BF437274 BE550189 CD366547 BM687199 AI810984 AA280902 CA427538
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for DHDDS (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | · | 10c | · | 10d |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | - | | - | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for DHDDS
|
Expression
for DHDDS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DHDDS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCCCAGAAT
About this image
See DHDDS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DHDDS
SOURCE GeneReport for Unigene cluster: Hs.369385
UniProtKB/Swiss-Prot: DHDDS_HUMAN, Q86SQ9Tissue specificity: Expressed at high levels in testis and kidney. Expressed in epididymis (at protein level). Slightlyexpressed in heart, spleen and thymus
SABiosciences Custom PCR Arrays for DHDDS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DHDDS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DHDDS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DHDDS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHDDS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHDDS |
Orthologs
for DHDDS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for DHDDS gene from 11/40 species (see all 40) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Dhdds1 , 5 |
dehydrodolichyl diphosphate synthase1, 5 |
88.19(n)1
92.49(a)1 |
|
4 (66.47 cM)5
674221 NM_026144.41 NP_080420.21
1339690285 |
chicken
(Gallus gallus) |
Aves |
DHDDS1 |
dehydrodolichyl diphosphate synthase |
75.98(n)
81.68(a) |
|
419543 XM_417694.2 XP_417694.2 |
lizard
(Anolis carolinensis) |
Reptilia |
DHDDS6 |
-- |
75(a) |
1 ↔ 1 |
GL343480.1(629346-634046) |
African clawed frog
(Xenopus laevis) |
Amphibia |
LOC3986262 |
hypothetical protein LOC398626 |
75.02(n) |
|
BC054312.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufd56c062 |
Transcribed sequence with moderate similarity to protein more |
75.85(n) |
|
CD758453.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG107781 |
CG10778 |
55.18(n)
50.68(a) |
|
31708 NM_132197.2 NP_572425.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
T01G1.41 |
Protein T01G1.4 |
51.9(n)
45.53(a) |
|
266904 NM_001028180.3 NP_001023351.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
RER2(YBR002C)4
RER21 |
Cis-prenyltransferase involved in dolichol synthesis; more4
Rer2p1 |
48.34(n)1
44.16(a)1 |
|
2(242568-241708)4
8522871, 4 NP_009556.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G175701 |
dehydrodolichyl diphosphate synthase 6 |
46.87(n)
39.46(a) |
|
816264 NM_127311.4 NP_565420.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.74782 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
80.17(n) |
|
AK069186.1 |
ENSEMBL Gene Tree for DHDDS (if available)
TreeFam Gene Tree for DHDDS (if available) |
Paralogs
for DHDDS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for DHDDS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DHDDS (26758773 - 26797797 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DHDDS: --
Human Gene Mutation Database (HGMD): DHDDS
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for DHDDS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DHDDS for disorders About GeneDecksing
OMIM gene information: 608172
OMIM disorders: --
UniProtKB/Swiss-Prot: DHDDS_HUMAN, Q86SQ9
Defects in DHDDS are the cause of retinitis pigmentosa type 59 (RP59) [MIM:613861]. RP59 is a retinaldystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigmentdeposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of conephotoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As theircondition progresses, they lose their far peripheral visual field and eventually central vision as well
11  diseases for DHDDS: About MalaCardsretinitis pigmentosa retinitis bullous pemphigoid pigmentary retinopathy
epididymitis dementia blindness pneumonia
tuberculosis malaria mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: DHDDS (1 document)
Export disorders for DHDDS gene to outside databases
|
Publications
for DHDDS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DHDDS gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with DHDDS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of human dehydrodolichyl diphosphate synthase gene. (PubMed id 12591616)1, 2, 3 Endo S.... Koyama T. (2003)
- Whole-exome sequencing links a variant in DHDDS to retinitis pigmentosa. (PubMed id 21295283)1, 2 Zuchner S.... Pericak-Vance M.A. (2011)
- Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins. (PubMed id 20736409)1, 2 Li J.... Liu Y. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Identification and characterization of a cDNA encoding a long-chain cis-isoprenyltranferase involved in dolichyl monophosphate biosynthesis in the ER of brain cells. (PubMed id 14652022)1, 2 Shridas P....Waechter C.J. (2003)
- In vivo interaction between the human dehydrodolichyl diphosphate synthase and the Niemann-Pick C2 protein revealed by a yeast two-hybrid system. (PubMed id 15110773)1, 9 Kharel Y....Koyama T. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Nogo-B receptor is necessary for cellular dolichol bi osynthesis and protein N-glycosylation. (PubMed id 21572394)2 Harrison K.D....Sessa W.C. (2011)
- A missense mutation in DHDDS, encoding dehydrodolichy l diphosphate synthase, is associated with autosomal-recessive retinitis pigmen tosa in Ashkenazi Jews. (PubMed id 21295282)1 Zelinger L....Sharon D. (2011)
|
External Searches for DHDDS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DHDDS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing DHDDS gene
(According to HUGE)
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Specialized Databases showing DHDDS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for DHDDS | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for DHDDS gene:
Search GeneIP for patents involving DHDDS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for DHDDS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DHDDS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DHDDS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DHDDS | | | OriGene Protein Over-expression Lysate for DHDDS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DHDDS | | OriGene 3'-UTR Clone for DHDDS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DHDDS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DHDDS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for DHDDS | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DHDDS | | OriGene Custom Protein Services for DHDDS | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DHDDS | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DHDDS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DHDDS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DHDDS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DHDDS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DHDDS |
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| | | | Search Tocris compounds for DHDDS |
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 | | | DHDDS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHDDS |
|  |  |  |  | | | | Search ThermoFisher Antibodies for DHDDS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DHDDS |
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