Free for academic non-profit institutions. Other users need a Commercial license

Aliases for DHCR24 Gene

Aliases for DHCR24 Gene

  • 24-Dehydrocholesterol Reductase 2 3 4 5
  • Desmosterol-To-Cholesterol Enzyme 2 3
  • Diminuto/Dwarf1 Homolog 3 4
  • Seladin-1 3 4
  • 3 Beta-Hydroxysterol Delta 24-Reductase 3
  • 3-Beta-Hydroxysterol Delta-24-Reductase 4
  • Delta(24)-Sterol Reductase 3
  • Selective AD Indicator 1 3
  • EC 4
  • Seladin 1 3
  • Nbla03646 3
  • SELADIN1 3
  • KIAA0018 4
  • DCE 3

External Ids for DHCR24 Gene

Previous HGNC Symbols for DHCR24 Gene

  • DCE

Previous GeneCards Identifiers for DHCR24 Gene

  • GC01M055152
  • GC01M054217
  • GC01M054659
  • GC01M054685
  • GC01M055027
  • GC01M055315
  • GC01M053429

Summaries for DHCR24 Gene

Entrez Gene Summary for DHCR24 Gene

  • This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]

GeneCards Summary for DHCR24 Gene

DHCR24 (24-Dehydrocholesterol Reductase) is a Protein Coding gene. Diseases associated with DHCR24 include Desmosterolosis and Alzheimer Disease. Among its related pathways are Metabolism and superpathway of tryptophan utilization. GO annotations related to this gene include enzyme binding and flavin adenine dinucleotide binding.

UniProtKB/Swiss-Prot for DHCR24 Gene

  • Catalyzes the reduction of the delta-24 double bond of sterol intermediates. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.

Gene Wiki entry for DHCR24 Gene

Additional gene information for DHCR24 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DHCR24 Gene

Genomics for DHCR24 Gene

Regulatory Elements for DHCR24 Gene

Enhancers for DHCR24 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H054856 1.5 Ensembl ENCODE dbSUPER 19.2 +27.4 27393 7.5 FOXA2 MLX ZFP64 ARID4B DMAP1 GATA2 FOS ATF7 RUNX3 PAF1 ENSG00000233203 DHCR24 LEXM ENSG00000242396 TTC22 ENSG00000237453 LDLRAD1 TCEANC2 TMEM59 TMEM61
GH01H054864 1.2 ENCODE dbSUPER 19.7 +20.7 20654 3.4 FOXA2 MLX ARID4B DMAP1 YY1 PAF1 SP5 MXD4 REST MIER2 ENSG00000233203 DHCR24 ENSG00000242396 TTC22 ENSG00000237453 LEXM TMEM61 PIR36544 GC01P054854
GH01H054934 1.2 FANTOM5 Ensembl ENCODE 16.1 -47.6 -47635 1.6 SOX13 GATAD2A FOXA2 TEAD1 ZNF384 DPF2 TEAD3 FOXA1 JUND GATA3 DHCR24 TMEM61 ENSG00000233203 ENSG00000242396 GC01M054936 GC01P054924
GH01H054882 1.4 ENCODE dbSUPER 12.3 +1.1 1055 7.8 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 SSBP3-AS1 LRRC42 ENSG00000233203 HSPB11 ENSG00000279049 DHCR24 TMEM61 TTC22 PARS2 ENSG00000237453
GH01H054945 1.3 FANTOM5 Ensembl ENCODE 10.7 -58.3 -58341 1.2 ELF3 CTCF KLF1 IRF2 SAP130 MAX ZNF2 RAD21 POLR2A SCRT2 TMEM61 ENSG00000233271 ENSG00000242396 ENSG00000233203 DHCR24 TTC22 ENSG00000237453 USP24 PIR41856 GC01M054936
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DHCR24 on UCSC Golden Path with GeneCards custom track

Promoters for DHCR24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000006704 248 1601 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF548 FOS SP3

Genomic Locations for DHCR24 Gene

Genomic Locations for DHCR24 Gene
37,622 bases
Minus strand

Genomic View for DHCR24 Gene

Genes around DHCR24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DHCR24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DHCR24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DHCR24 Gene

Proteins for DHCR24 Gene

  • Protein details for DHCR24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Delta(24)-sterol reductase
    Protein Accession:
    Secondary Accessions:
    • B7Z817
    • D3DQ51
    • Q9HBA8

    Protein attributes for DHCR24 Gene

    516 amino acids
    Molecular mass:
    60101 Da
    Name=FAD; Xref=ChEBI:CHEBI:57692;
    Quaternary structure:
    No Data Available
    • Sequence=BAA02806.3; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for DHCR24 Gene


neXtProt entry for DHCR24 Gene

Post-translational modifications for DHCR24 Gene

  • Ubiquitination at isoforms=2254, posLast=301301, posLast=313313, posLast=367367, posLast=376376, posLast=492492, posLast=496496, and isoforms=2509
  • Modification sites at PhosphoSitePlus

Other Protein References for DHCR24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DHCR24 Gene

Domains & Families for DHCR24 Gene

Gene Families for DHCR24 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for DHCR24 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
  • Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
genes like me logo Genes that share domains with DHCR24: view

Function for DHCR24 Gene

Molecular function for DHCR24 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
5-alpha-cholest-7-en-3-beta-ol + NADP(+) = 5-alpha-cholesta-7,24-dien-3-beta-ol + NADPH.
UniProtKB/Swiss-Prot Function:
Catalyzes the reduction of the delta-24 double bond of sterol intermediates. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.

Enzyme Numbers (IUBMB) for DHCR24 Gene

Gene Ontology (GO) - Molecular Function for DHCR24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000246 delta24(24-1) sterol reductase activity IMP 11519011
GO:0003824 catalytic activity IEA --
GO:0016491 oxidoreductase activity IEA --
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEA --
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IDA 11519011
genes like me logo Genes that share ontologies with DHCR24: view
genes like me logo Genes that share phenotypes with DHCR24: view

Human Phenotype Ontology for DHCR24 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for DHCR24 Gene

MGI Knock Outs for DHCR24:

Animal Model Products

Clone Products

No data available for Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for DHCR24 Gene

Localization for DHCR24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DHCR24 Gene

Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DHCR24 gene
Compartment Confidence
nucleus 5
endoplasmic reticulum 5
golgi apparatus 5
cytoskeleton 3
cytosol 2
plasma membrane 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for DHCR24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005634 nucleus IEA,IDA 15577914
GO:0005737 cytoplasm IEA --
GO:0005783 endoplasmic reticulum IDA,IEA 11007892
GO:0005789 endoplasmic reticulum membrane TAS --
genes like me logo Genes that share ontologies with DHCR24: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for DHCR24 Gene

Pathways & Interactions for DHCR24 Gene

genes like me logo Genes that share pathways with DHCR24: view

UniProtKB/Swiss-Prot Q15392-DHC24_HUMAN

  • Pathway: Steroid biosynthesis; cholesterol biosynthesis.

Gene Ontology (GO) - Biological Process for DHCR24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process IEA --
GO:0006694 steroid biosynthetic process IEA --
GO:0006695 cholesterol biosynthetic process ISS,IMP --
GO:0006915 apoptotic process NAS 11007892
GO:0006979 response to oxidative stress IEP 11007892
genes like me logo Genes that share ontologies with DHCR24: view

No data available for SIGNOR curated interactions for DHCR24 Gene

Drugs & Compounds for DHCR24 Gene

(4) Drugs for DHCR24 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
FAD Approved Pharma 0
cholesterol Experimental Pharma Agonist 0
Lanosterin Experimental Pharma 0

(22) Additional Compounds for DHCR24 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • 24-Dehydrocholesterol
  • 3beta-cholesta-5,24-dien-3-ol
  • Cholest-5,24-dien-3beta-ol
  • Cholesta-5,24-dien-3-ol
  • Cholesta-5,24-dien-3b-ol
  • (3b)-Ergosta-5,24(28)-dien-3-ol
  • 24-Methylencholesterol
  • 24-Methylene-Cholesterol
  • Chalinasterol
  • Ergosta-5, 24(28)-dien-3b-ol
  • (3beta,5alpha)-4,4-dimethylcholesta-8,24-dien-3-ol
  • 14-Demethyllanosterol
  • 4,4-Dimethyl-5 alpha -cholesta-8,24-dien-3 beta -ol
  • 4,4-Dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
  • 4,4-Dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol
  • 3beta-hydroxy-4,4-dimethyl-8(9)-cholestene
  • 3beta-hydroxy-4,4-dimethylcholest-8(9)-ene
  • 4,4-Dimethyl-3beta-hydroxy-8(9)-cholestene
  • 4,4-Dimethyl-3beta-hydroxycholest-8(9)-ene
  • 4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
genes like me logo Genes that share compounds with DHCR24: view

Transcripts for DHCR24 Gene

mRNA/cDNA for DHCR24 Gene

Unigene Clusters for DHCR24 Gene

24-dehydrocholesterol reductase:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for DHCR24 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
SP1: - - -
SP3: -
SP4: -
SP5: - - -

Relevant External Links for DHCR24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DHCR24 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DHCR24 Gene

mRNA differential expression in normal tissues according to GTEx for DHCR24 Gene

This gene is overexpressed in Adrenal Gland (x12.3), Liver (x5.5), and Brain - Spinal cord (cervical c-1) (x4.1).

Protein differential expression in normal tissues from HIPED for DHCR24 Gene

This gene is overexpressed in Fetal testis (45.1) and Adrenal (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for DHCR24 Gene

NURSA nuclear receptor signaling pathways regulating expression of DHCR24 Gene:


SOURCE GeneReport for Unigene cluster for DHCR24 Gene:


mRNA Expression by UniProt/SwissProt for DHCR24 Gene:

Tissue specificity: Highly expressed in brain and adrenal gland with moderate expression in liver, lung, spleen, prostate and spinal cord. Low expression in heart, uterus and prostate. Undetectable in blood cells. In the brain, strongly expressed in cortical regions, substantia nigra, caudate nucleus, hippocampus, medulla oblongata and pons. In brains affected by Alzheimer disease, expression in the inferior temporal lobe is substantially lower than in the frontal cortex.

Evidence on tissue expression from TISSUES for DHCR24 Gene

  • Nervous system(5)
  • Liver(4.8)
  • Bone marrow(4)
  • Lung(3.8)
  • Skin(3.8)
  • Intestine(3.5)
  • Kidney(3.4)
  • Adrenal gland(3.2)
  • Eye(3.1)
  • Stomach(2.5)
  • Muscle(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for DHCR24 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
  • cardiovascular
  • digestive
  • integumentary
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
Head and neck:
  • brain
  • cerebellum
  • cerebrospinal fluid
  • chin
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • forehead
  • head
  • jaw
  • lip
  • mandible
  • maxilla
  • meninges
  • mouth
  • neck
  • nose
  • outer ear
  • skull
  • tooth
  • chest wall
  • clavicle
  • heart
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
  • pelvis
  • penis
  • testicle
  • urethra
  • vulva
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
  • blood
  • blood vessel
  • peripheral nervous system
  • skin
  • spinal column
  • spinal cord
  • vertebrae
genes like me logo Genes that share expression patterns with DHCR24: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein tissue co-expression partners for DHCR24 Gene

Orthologs for DHCR24 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DHCR24 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia DHCR24 33 34
  • 99.22 (n)
(Canis familiaris)
Mammalia DHCR24 33 34
  • 92.89 (n)
(Bos Taurus)
Mammalia DHCR24 33 34
  • 91.86 (n)
(Mus musculus)
Mammalia Dhcr24 33 16 34
  • 91.34 (n)
(Rattus norvegicus)
Mammalia Dhcr24 33
  • 90.83 (n)
(Ornithorhynchus anatinus)
Mammalia DHCR24 34
  • 89 (a)
(Monodelphis domestica)
Mammalia DHCR24 34
  • 46 (a)
(Gallus gallus)
Aves DHCR24 33 34
  • 76.16 (n)
(Anolis carolinensis)
Reptilia DHCR24 34
  • 77 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia dhcr24 33
  • 70.54 (n)
(Danio rerio)
Actinopterygii dhcr24 33 34
  • 73.64 (n)
(Caenorhabditis elegans)
Secernentea F52H2.6 35 33 34
  • 53.27 (n)
Y7A5A.1 35
  • 38 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons DWF1 33
  • 52.84 (n)
(Oryza sativa)
Liliopsida Os10g0397400 33
  • 55.51 (n)
Os.7216 33
(Hordeum vulgare)
Liliopsida Hv.3024 33
(Triticum aestivum)
Liliopsida Ta.28334 33
(Zea mays)
Liliopsida Zm.6146 33
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 61 (a)
Species where no ortholog for DHCR24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for DHCR24 Gene

Gene Tree for DHCR24 (if available)
Gene Tree for DHCR24 (if available)

Paralogs for DHCR24 Gene

(1) SIMAP similar genes for DHCR24 Gene using alignment to 4 proteins: Pseudogenes for DHCR24 Gene

genes like me logo Genes that share paralogs with DHCR24: view

No data available for Paralogs for DHCR24 Gene

Variants for DHCR24 Gene

Sequence variations from dbSNP and Humsavar for DHCR24 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs281797256 Pathogenic, Desmosterolosis (DESMOS) [MIM:602398] 54,865,405(+) ACATG(C/G)TTAAA reference, missense
rs281797257 Pathogenic, Desmosterolosis (DESMOS) [MIM:602398] 54,865,442(+) TGCTA(G/T)TCAGC reference, missense
rs28939092 Pathogenic, Desmosterolosis (DESMOS) [MIM:602398] 54,852,372(-) GCTGT(A/C)TGCCG reference, missense
rs28939093 Desmosterolosis (DESMOS) [MIM:602398]
rs119475041 Pathogenic 54,875,134(-) CTTAC(A/C/G)AGCTG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for DHCR24 Gene

Variant ID Type Subtype PubMed ID
nsv829915 CNV gain 17160897
nsv817614 CNV gain 22305530
nsv546266 CNV gain 21841781
nsv461561 CNV gain 19166990
nsv1133854 CNV deletion 24896259
esv995636 CNV deletion 20482838
esv6509 CNV gain 19470904
esv3586105 CNV loss 21293372
esv3586104 CNV loss 21293372
esv3577874 CNV loss 25503493
esv2748386 CNV deletion 23290073
esv2748375 CNV deletion 23290073
esv2676460 CNV deletion 23128226
esv2078805 CNV deletion 18987734
esv1764339 CNV deletion 17803354

Variation tolerance for DHCR24 Gene

Residual Variation Intolerance Score: 13.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.08; 38.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for DHCR24 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DHCR24 Gene

Disorders for DHCR24 Gene

MalaCards: The human disease database

(5) MalaCards diseases for DHCR24 Gene - From: HGMD, OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
  • deficiency of 3beta-hydroxysterol delta24-reductase
alzheimer disease
  • alzheimer disease, late-onset
restrictive dermopathy, lethal
  • lethal restrictive dermopathy
x-linked chondrodysplasia punctata
  • chondrodystrophia calcificans congenita
mevalonic aciduria
  • mevalonate kinase deficiency
- elite association - COSMIC cancer census association via MalaCards


  • Desmosterolosis (DESMOS) [MIM:602398]: Rare autosomal recessive disorder characterized by multiple congenital anomalies and elevated levels of the cholesterol precursor desmosterol in plasma, tissue, and cultured cells. {ECO:0000269 PubMed:11519011}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for DHCR24

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with DHCR24: view

No data available for Genatlas for DHCR24 Gene

Publications for DHCR24 Gene

  1. Mutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis. (PMID: 11519011) Waterham HR … Wanders RJ (American journal of human genetics 2001) 2 3 4 22 60
  2. The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress. (PMID: 11007892) Greeve I … Nitsch RM (The Journal of neuroscience : the official journal of the Society for Neuroscience 2000) 3 4 22 60
  3. The membrane topological analysis of 3β-hydroxysteroid-Delta24 reductase (DHCR24) on endoplasmic reticulum. (PMID: 22010141) Lu X … Gao B (Journal of molecular endocrinology 2012) 3 4 60
  4. Inhibition of DHCR24/seladin-1 impairs cellular homeostasis in prostate cancer. (PMID: 20166102) Battista MC … Gallo-Payet N (The Prostate 2010) 3 22 60
  5. Seladin-1 expression is regulated by promoter methylation in adrenal cancer. (PMID: 20465827) Simi L … Orlando C (BMC cancer 2010) 3 22 60

Products for DHCR24 Gene

Sources for DHCR24 Gene

Loading form....