DGKG Gene
protein-coding GIFtS: 65
GCID: GC03M185823
|
|
diacylglycerol kinase, gamma 90kDa(Previous names: diacylglycerol kinase, gamma (90kD) )
(Previous symbol: DAGK3)
| |
Aliases
for DGKG gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Diacylglycerol Kinase, Gamma 90kDa1 2 | | Diacylglycerol Kinase, Gamma (90kD)1 | | DAGK31 2 3 5 | | DGK-GAMMA2 | | Diglyceride Kinase Gamma2 3 | | Diacylglycerol Kinase Gamma2 | | DAG Kinase Gamma2 3 | | Diacylglyerol Kinase Gamma2 | | EC 2.7.1.1073 8 | | DGK-Gamma1 |
Export aliases for DGKG gene to outside databasesPrevious GC identifers: GC03M182638 GC03M187124 GC03M187269 GC03M187187 GC03M187349 GC03M183274 |
Summaries
for DGKG gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DGKG:
This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved inlipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, afundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanylnucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has beenimplicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells.Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: DGKG_HUMAN, P49619Function: Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidicacid
 summary
for DGKG: Diacylglycerol kinases (DGKs) are a group of ten enzymes (DGKalpha, DGKbeta, DGKgamma, DGKdelta, DGKepsilon,
DGKzeta, DGKeta, DGKtheta, DGKiota and DGKkappa) that metabolize 1,2,diacylglycerol (DAG) to produce
phosphatidic acid (PA). They all contain a conserved C'-terminal catalytic domain, two cysteine-rich
Zn2+-finger motifs that bind DAG and an ATP-binding site, whilst the regulatory domain varies. DGKs are
widely distributed throughout mammalian tissues and different isozymes have different subcellular
localizations; some are cytosolic (for example DGKalpha), some are membrane-bound (for example DGKgamma is
associated with the Golgi membrane) and some are nuclear (for example DGKzeta. DGKs have diverse biological
roles as they participate in signal transduction by modulating levels of DAG in a variety of cellular
responses to extracellular stimuli.
Gene Wiki entry for DGKG
|
Genomic Views
for DGKG gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DGKG gene promoter:
RFX1 AML1a NRSF form 1 XBP-1 Nkx2-5 Tal-1beta NRSF form 2 Evi-1 ITF-2 Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for DGKG
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DGKG |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q27.2-q27.3 Ensembl cytogenetic band: 3q27.3 HGNC cytogenetic band: 3q27-q28DGKG Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M185823: view genomic region
(about GC identifiers)
Start:
|
185,823,457 bp from pter |
End:
|
186,080,026 bp from pter |
Size:
|
256,570 bases |
Orientation:
|
minus strand |
|
Proteins
for DGKG gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DGKG_HUMAN, P49619 (See
protein sequence)Recommended Name: Diacylglycerol kinase gamma Size: 791 amino acids; 89124 Da
Subcellular location: Cytoplasm. Membrane. Note=Can be loosely bound to the membranes
Secondary accessions: B2RAH4 Q2M1H4 Q5FWG1Alternative splicing: 3 isoforms: P49619-1 P49619-2 P49619-3 (May be inactive)Explore the universe of human proteins at neXtProt for DGKG: NX_P49619
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P49619
4/11 DME Specific Peptides for DGKG (P49619) (see all 11)
DGKG Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001074213.1 NP_001074214.1 NP_001337.2
ENSEMBL proteins: ENSP00000265022 ENSP00000339777 ENSP00000371599 ENSP00000395526 ENSP00000440507 Reactome Protein details: P49619
Human Recombinant Protein Products for DGKG:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
DGKG for ontologies About GeneDecksing
DGKG Antibody Products:
Assay Products for DGKG: |
Protein
Domains /
Families
for DGKG gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DGKG for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry P49619ProtoNet protein and cluster: P49619 1 Blocks protein family: IPB000756 Diacylglycerol kinase accessory domain (presumed)
UniProtKB/Swiss-Prot: DGKG_HUMAN, P49619Similarity: Belongs to the eukaryotic diacylglycerol kinase familySimilarity: Contains 1 DAGKc domainSimilarity: Contains 2 EF-hand domainsSimilarity: Contains 2 phorbol-ester/DAG-type zinc fingers |
Function
for DGKG gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: DGKG_HUMAN, P49619Function: Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidicacidCatalytic activity: ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphateEnzyme regulation: Requires phosphatidylserine for maximal activity Genatlas biochemistry entry for DGKG:diacylglycerol kinase gamma,90kDa,predominantly expressed in the retina and brain
Enzyme Number (IUBMB): EC 2.7.1.1071 2
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
DGKG for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for DGKG:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DGKG (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DGKG (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): DGKG (NM_001346) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DGKG | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DGKG |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DGKG |
|
Pathways & Interactions
for DGKG gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by GPCR | | | 2 | Platelet activation, signaling and aggregation | | | 3 | G alpha (q) signalling events | | | 4 | Effects of PIP2 hydrolysis | | | 5 | Glycerolipid metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/8 
Reactome Pathways for DGKG (see all 8)
4 
Kegg Pathways (Kegg details for DGKG):
DGKG for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DGKG
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/58 Interacting proteins for DGKG (P496193 ENSP000002650224) via UniProtKB, MINT, STRING, and/or I2D (see all 58)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007165 | signal transduction |
TAS | 8034597 | | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway |
IEA | -- | | GO:0007596 | blood coagulation |
TAS | -- | | GO:0030168 | platelet activation |
TAS | -- | | GO:0035556 | intracellular signal transduction |
IEA | -- |
DGKG for ontologies About GeneDecksing
|
Drugs & Compounds
for DGKG gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for DGKG available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| R 59-022 | Diacylglycerol kinase inhibitor; increases PKC activity | [93076-89-2] | | Dioctanoylglycol | Diacylglycerol kinase inhibitor | [627-86-1] |
10/979 HMDB Compounds for DGKG (see all 979) About this table
1 DrugBank Compound for DGKG About this table
Search CenterWatch for drugs/clinical trials and news about DGKG
|
Transcripts
for DGKG gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DGKG gene (3 alternative transcripts): NM_001080744.1 NM_001080745.1 NM_001346.2 Unigene Cluster for DGKG: Diacylglycerol kinase, gamma 90kDa Hs.683449 [show with all ESTs]Unigene Representative Sequence: NM_00134612 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000447054 ENST00000265022(uc003fqa.3 uc003fqb.3 uc003fqc.3 uc011brx.2)
ENST00000344484 ENST00000382164 ENST00000490452 ENST00000480809 ENST00000480933
ENST00000472506 ENST00000437018 ENST00000482566 ENST00000466466 ENST00000544847
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DGKG (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DGKG (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): DGKG (NM_001346) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DGKG | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DGKG |
Additional cDNA sequence: AK304440.1 AK309682.1 AK314192.1 AY737485.1 BC089411.1 BC112363.1 D26135.1 9 DOTS entries: DT.95157297 DT.308008 DT.210019 DT.120850237 DT.108989 DT.120850219 DT.92418110 DT.95357404 DT.92070471 24/53 AceView cDNA sequences (see all 53): BM669549 BI038311 BQ898097 BE468027 CA391741 AW770587 BX954094 AA933006 BF792878 BQ879937 D26135 AL598473 CD365475 AV707323 BQ549212 BX505681 AI911283 AI418168 T16476 BF223746 AI681741 BM673524 AV706116 BQ440190
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for DGKG About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 |
|---|
|
| SP1: | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | |
| SP4: | | | | | | | | | | |
ECgene alternative splicing isoforms for DGKG
|
Expression
for DGKG gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DGKG expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTCTACCCC
About this image
See DGKG Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DGKG
SOURCE GeneReport for Unigene cluster: Hs.683449
UniProtKB/Swiss-Prot: DGKG_HUMAN, P49619Tissue specificity: Predominantly expressed in retina and in a much lesser extent in the brain. Other tissues containextremely low levels of DGK-gamma
SABiosciences Custom PCR Arrays for DGKG
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DGKG
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DGKG | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DGKG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DGKG | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DGKG |
Orthologs
for DGKG gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DGKG gene from 7/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
DGKG1 |
diacylglycerol kinase, gamma 90kDa |
71.68(n)
69(a) |
|
424839 XM_422650.3 XP_422650.3 |
lizard
(Anolis carolinensis) |
Reptilia |
DGKG6 |
-- |
65(a) |
1 ↔ 1 |
3(34054371-34166740) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:dkey-189g17.36 |
si:dkey-189g17.3 |
58(a) |
1 ↔ 1 |
9(23480929-23651903) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Dgk3 |
phosphatidylinositol biosynthesis
diacylglycerol more |
55(a) |
|
43E18 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
dgk-33 |
Diacylglycerol kinase |
45(a) |
|
III(9234802-9239752) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
DGK26DGK16(see all 7) |
diacylglycerol kinase1(see all 7) |
25(a)23(a)(see all 7) |
many ↔ manymany ↔ many(see all 7) |
5(25518641-25523621) 5(2524778-2529330) |
rice
(Oryza sativa) |
Liliopsida |
Os03g04253001 |
hypothetical protein |
49.77(n)
44.79(a) |
|
9266342 NM_001186551.1 NP_001173480.1 |
ENSEMBL Gene Tree for DGKG (if available)
TreeFam Gene Tree for DGKG (if available) |
Paralogs
for DGKG gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DGKG gene
- DGKA2 DGKH2 DGKQ2 DGKB2 DGKD2 DGKI2 DGKE2 DGKZ2
4 SIMAP similar genes for DGKG using alignment to 4 protein entries: DGKG_HUMAN (see all proteins):DGKB DAGK1 DGKA PRKCH
DGKG for paralogs About GeneDecksing
|
Genomic Variants
for DGKG gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DGKG (185823457 - 186073457 bp, first 250kb of DGKG)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for DGKG
1 Indel: 59113 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DGKG |
|
Disorders
/ Diseases
for DGKG gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DGKG for disorders About GeneDecksing
OMIM gene information: 601854
OMIM disorders: --
9  diseases for DGKG: About MalaCardsleukemia optic atrophy aggressive periodontitis periodontitis
pharyngitis asthma obesity cerebritis
neuronitis
Human Genome Epidemiology (HuGE) Navigator: DGKG (5 documents)
Export disorders for DGKG gene to outside databases
|
Publications
for DGKG gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DGKG gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with DGKG) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in human retina with a truncated and inactive enzyme expression in most other human cells. (PubMed id 8034597)1, 2, 3, 9 Kai M.... Kanoh H. (1994)
- Phosphorylation and up-regulation of diacylglycerol kinase gamma via its interaction with protein kinase C gamma. (PubMed id 16905533)1, 7, 9 Yamaguchi Y....Saito N. (2006)
- Mapping and genomic characterization of the gene encoding diacylglycerol kinase gamma (DAGK3): assessment of its role in dominant optic atrophy (OPA1). (PubMed id 10071200)1, 2, 9 Stoehr H.... Weber B.H.F. (1999)
- Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase gamma with the Src homology 2 and C1 domains of beta2-chimaerin. (PubMed id 17803461)1, 9 Yasuda S....Sakane F. (2008)
- Nuclear transportation of diacylglycerol kinase gamma and its possible function in the nucleus. (PubMed id 16407189)1, 9 Matsubara T....Saito N. (2006)
- Diacylglycerol kinase gamma serves as an upstream suppressor of Rac1 and lamellipodium formation. (PubMed id 15102830)1, 9 Tsushima S....Sakane F. (2004)
- Regulatory role of diacylglycerol kinase gamma in macrophage differentiation of leukemia cells. (PubMed id 12732202)1, 9 Yamada K....Kanoh H. (2003)
- EF-hand motifs of alpha, beta and gamma isoforms of diacylglycerol kinase bind calcium with different affinities and conformational changes. (PubMed id 9003401)1, 9 Yamada K....Kanoh H. (1997)
- Implication of genetic variants near NEGR1, SEC16B, T MEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, a nd KCTD15 with obesity and type 2 diabetes in 7705 Chinese. (PubMed id 20215397)1 Ng M.C....Ma R.C. (2010)
- Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1 MelAcn E....Lasky-Su J. (2010)
|
External Searches for DGKG gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DGKG gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DGKG gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DGKG gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for DGKG gene:
Search GeneIP for patents involving DGKG
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for DGKG gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DGKG | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DGKG | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DGKG | | | OriGene Protein Over-expression Lysate for DGKG | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DGKG | | OriGene 3'-UTR Clone for DGKG | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DGKG | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DGKG | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for DGKG | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DGKG | | OriGene Custom Protein Services for DGKG | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DGKG | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DGKG | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DGKG | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DGKG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DGKG | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DGKG |
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| | | | Tocris compounds for DGKG |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DGKG |
|  |  |  |  | | | | ThermoFisher Antibody for DGKG |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DGKG |
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