DGKE Gene
protein-coding GIFtS: 63
GCID: GC17P054911
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|
diacylglycerol kinase, epsilon 64kDa(Previous names: diacylglycerol kinase, epsilon (64kD) )
| |
Aliases for DGKE gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Diacylglycerol Kinase, Epsilon 64kDa1 2 | | DAG Kinase Epsilon2 3 | | DAGK61 2 | | EC 2.7.1.1073 8 | | DGK1 2 | | Diacylglycerol Kinase, Epsilon (64kD)1 | | Diglyceride Kinase Epsilon2 3 | | NPHS72 | | DAGK52 3 | | Diacylglycerol Kinase Epsilon2 | | DGK-Epsilon1 | | |
Export aliases for DGKE gene to outside databasesPrevious GC identifers: GC17P054648 GC17P057392 GC17P055253 GC17P055386 GC17P052266 GC17P050271 |
Summaries for DGKE gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for DGKE: Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) fromdiacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon showsspecificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. (provided byRefSeq, Jul 2008) UniProtKB/Swiss-Prot: DGKE_HUMAN, P52429Function: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signalstransmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acidcomposition
summary
for DGKE: Diacylglycerol kinases (DGKs) are a group of ten enzymes (DGKalpha, DGKbeta, DGKgamma, DGKdelta, DGKepsilon, DGKzeta, DGKeta, DGKtheta, DGKiota and DGKkappa) that metabolize 1,2,diacylglycerol (DAG) to produce phosphatidic acid (PA). They all contain a conserved C'-terminal catalytic domain, two cysteine-rich Zn2+-finger motifs that bind DAG and an ATP-binding site, whilst the regulatory domain varies. DGKs are widely distributed throughout mammalian tissues and different isozymes have different subcellular localizations; some are cytosolic (for example DGKalpha), some are membrane-bound (for example DGKgamma is associated with the Golgi membrane) and some are nuclear (for example DGKzeta. DGKs have diverse biological roles as they participate in signal transduction by modulating levels of DAG in a variety of cellular responses to extracellular stimuli.
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Genomic Views for DGKE gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DGKE gene promoter: RFX1 FOXO3 MIF-1 FOXO3b HEN1 AREB6 MEF-2A NRF-2 FOXO3a aMEF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for DGKE
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DGKE |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q22 Ensembl cytogenetic band: 17q22 HGNC cytogenetic band: 17q22DGKE Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P054911: view genomic region
(about GC identifiers)
Start:
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54,911,460 bp from pter |
End:
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54,946,036 bp from pter |
Size:
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34,577 bases |
Orientation:
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plus strand |
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Proteins for DGKE gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: DGKE_HUMAN, P52429 (See
protein sequence)Recommended Name: Diacylglycerol kinase epsilon Size: 567 amino acids; 63927 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: Q9UKQ3Explore the universe of human proteins at neXtProt for DGKE: NX_P52429
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P52429 3 DME Specific Peptides for DGKE (P52429)
DGKE Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_003638.1 ENSEMBL proteins: ENSP00000284061 ENSP00000459295 ENSP00000458493 ENSP00000459958 Reactome Protein details: P52429 Human Recombinant Protein Products for DGKE:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
DGKE for ontologies About GeneDecksing
DGKE Antibody Products: Assay Products for DGKE: |
Protein
Domains / Families for DGKE gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DGKE for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P52429ProtoNet protein and cluster: P52429 1 Blocks protein family: IPB000756 Diacylglycerol kinase accessory domain (presumed)
UniProtKB/Swiss-Prot: DGKE_HUMAN, P52429Similarity: Belongs to the eukaryotic diacylglycerol kinase familySimilarity: Contains 1 DAGKc domainSimilarity: Contains 2 phorbol-ester/DAG-type zinc fingers |
Function for DGKE gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: DGKE_HUMAN, P52429Function: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signalstransmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acidcompositionCatalytic activity: ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate Genatlas biochemistry entry for DGKE:diacylglycerol kinase epsilon,expressed predominantly in the testis and the retina,converting diacylglycerol tophosphatidic acid,involved in the phosphorylation of arachidonate containing diacylglycerol, Enzyme Number (IUBMB): EC 2.7.1.1071 2
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
DGKE for ontologies About GeneDecksing
Phenotypes: 1 GenomeRNAi human phenotype for DGKE: 2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Dgke):
DGKE for phenotypes About GeneDecksing
Animal Models: Mouse knock-out Dgketm1Ngb for DGKE
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DGKE (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DGKE OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DGKE (NM_003647) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DGKE | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DGKE  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DGKE |
|
Pathways & Interactions for DGKE gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by GPCR | | | 2 | Platelet activation, signaling and aggregation | | | 3 | G alpha (q) signalling events | | | 4 | Effects of PIP2 hydrolysis | | | 5 | Glycerolipid metabolism | |
Pathway sources See GeneCards unified pathways Show all pathways
5/8
Reactome Pathways for DGKE (see all 8)
4
Kegg Pathways (Kegg details for DGKE):
DGKE for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DGKE
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/48 Interacting proteins for DGKE (P524293 ENSP000002840614) via UniProtKB, MINT, STRING, and/or I2D (see all 48)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway |
IEA | -- | | GO:0007596 | blood coagulation |
TAS | -- | | GO:0008654 | phospholipid biosynthetic process |
TAS | 8626589 | | GO:0030168 | platelet activation |
TAS | -- | | GO:0035556 | intracellular signal transduction |
IEA | -- |
DGKE for ontologies About GeneDecksing
|
Drugs & Compounds for DGKE gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
DGKE for compounds About GeneDecksing
Compounds for DGKE available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| R 59-022 | Diacylglycerol kinase inhibitor; increases PKC activity | [93076-89-2] | | Dioctanoylglycol | Diacylglycerol kinase inhibitor | [627-86-1] |
10/862 HMDB Compounds for DGKE (see all 862) About this table 6 Novoseek chemical compound relationships for DGKE gene About this table
Search CenterWatch for drugs/clinical trials and news about DGKE 
|
Transcripts for DGKE gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for DGKE gene: NM_003647.2 Unigene Cluster for DGKE: Diacylglycerol kinase, epsilon 64kDa Hs.239514 [show with all ESTs]Unigene Representative Sequence: NM_0036476 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000284061(uc002iur.3) ENST00000572810 ENST00000576869 ENST00000572944(uc002ius.1) ENST00000571084 ENST00000570738
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DGKE (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DGKE OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DGKE (NM_003647) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DGKE | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DGKE  |
Additional cDNA sequence: AB209365.1 AK057591.1 AK129803.1 AK293039.1 AK310668.1 BC022297.1 BC130629.1 BC130631.1 U49379.1 5 DOTS entries: DT.432573 DT.310317 DT.120927290 DT.92036162 DT.120956139 24/28 AceView cDNA sequences (see all 28): CA391764 CR622919 BX329274 BX390069 AA287006 BM983232 AI688534 BC022297 AL706818 BX089763 BF732316 BG770880 NM_003647 U49379 BX506599 AL555194 AA278962 AL555193 AA284392 AA807749 BQ307355 AA252464 BF107055 AA764732 GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for DGKE About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | |
| SP1: | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for DGKE
|
Expression for DGKE gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DGKE expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CATTTTTATT
 About this image See DGKE Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DGKE
SOURCE GeneReport for Unigene cluster: Hs.239514
UniProtKB/Swiss-Prot: DGKE_HUMAN, P52429Tissue specificity: Expressed predominantly in testis SABiosciences Custom PCR Arrays for DGKE
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DGKE Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DGKE | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DGKE | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DGKE | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DGKE |
Orthologs for DGKE gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DGKE gene from 7/21 species (see all 21) About this table
ENSEMBL Gene Tree for DGKE (if available) TreeFam Gene Tree for DGKE (if available)  |
Paralogs for DGKE gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for DGKE gene
- DGKH2 DGKQ2 DGKB2 DGKI2 DGKZ2 DGKA2 DGKG2 DGKD2
2 SIMAP similar genes for DGKE using alignment to 5 protein entries: DGKE_HUMAN (see all proteins):DGKQ DGKA
DGKE for paralogs About GeneDecksing
|
Genomic Variants for DGKE gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for DGKE (54911460 - 54946036 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for DGKE 1 CNV: 7166  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DGKE |
|
Disorders
/ Diseases for DGKE gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DGKE for disorders About GeneDecksing
OMIM gene information: 601440
OMIM disorders: --
9 diseases for DGKE: About MalaCardsretinal degeneration retinitis pigmentosa insulin resistance retinitis hyperglycemia hypoxia malaria leukemia neuronitis
1 Novoseek disease relationship for DGKE gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| retinal degeneration |
44 |
3 |
10798401 (1), 9183747 (1) |
Human Genome Epidemiology (HuGE) Navigator: DGKE (2 documents) Export disorders for DGKE gene to outside databases
|
Publications for DGKE gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DGKE gene, integrated from 9 sources (see all 51): (articles sorted by number of sources associating them with DGKE) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates. (PubMed id 8626589)1, 2, 3, 9 Tang W.... Prescott S.M. (1996)
- Characterization of the human diacylglycerol kinase epsilon gene and its assessment as a candidate for inherited retinitis pigmentosa. (PubMed id 10571048)1, 2, 9 Tang W.... Prescott S.M. (1999)
- Cytogenetic assignment and physical mapping of the human DGKE gene to chromosome 17q22. (PubMed id 10051413)1, 3 Hart T.C....Van Dyke T.E. (1999)
- Role of the hydrophobic segment of diacylglycerol kinase epsilon. (PubMed id 17455907)1, 9 Dicu A.O....Epand R.M. (2007)
- Diacylglycerol kinase epsilon is selective for both a cyl chains of phosphatidic acid or diacylglycerol. (PubMed id 19744926)1, 9 Lung M....Epand R.M. (2009)
- Catalytic activity and acyl-chain selectivity of diacy lglycerol kinase E are modulated by residues in and near the lipoxygenase-like m otif. (PubMed id 22266092)1 D'Souza K. and Epand R.M. (2012)
- Inhibition of lipid signaling enzyme diacylglycerol ki nase epsilon attenuates mutant huntingtin toxicity. (PubMed id 22511757)1 Zhang N....Ellerby L.M. (2012)
- Reversal of redox-dependent inhibition of diacylglyce rol kinase by antioxidants in mesangial cells exposed to high glucose. (PubMed id 21725595)1 Atsumi H....Koya D. (2011)
- Endocannabinoids and diacylglycerol kinase activity. (PubMed id 21194521)1 Gantayet A....Epand R.M. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for DGKE gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing DGKE gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DGKE gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DGKE gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for DGKE | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DGKE gene: Search GeneIP for patents involving DGKE
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for DGKE gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for DGKE | | OriGene shRNA RFP for DGKE | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DGKE | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DGKE | | OriGene Protein Over-expression Lysate for DGKE | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for DGKE | | OriGene 3'-UTR Clone for DGKE | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DGKE | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DGKE | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for DGKE | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for DGKE | | OriGene Custom Protein Services for DGKE | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DGKE | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DGKE | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DGKE | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DGKE | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DGKE | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DGKE |
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| | | Tocris compounds for DGKE |
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 | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DGKE |
|  |  |  |  | | | ThermoFisher Antibodies for DGKE |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DGKE |
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