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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DGCR14 Gene

protein-coding   GIFtS: 53
GCID: GC22M019117

DiGeorge syndrome critical region gene 14

(Previous name: DiGeorge syndrome critical region gene 13 )
(Previous symbol: DGCR13)
 Explore 5 diseases affiliated with
DGCR14 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for DGCR14    

Aliases
for DGCR14 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
DiGeorge Syndrome Critical Region Gene 141 2     DiGeorge Syndrome Protein H2 3
DGSI1 2 3 5     DGSH2 3
DGCR131 2 3     DGS-I2
DGS-H1 2 3     DiGeorge Syndrome Critical Region Gene DGSI2
ES21 2 3     DiGeorge Syndrome Gene H2
Es2el1 2     DiGeorge Syndrome Gene I2
DiGeorge Syndrome Critical Region Gene 131 2     Protein DGCR132
DiGeorge Syndrome Critical Region 132 3     Protein DGCR142
DiGeorge Syndrome Critical Region 142 3     Protein ES23

External Ids:    HGNC: 168171   Entrez Gene: 82202   Ensembl: ENSG000001000567   OMIM: 6017555   UniProtKB: Q96DF83   

Export aliases for DGCR14 gene to outside databases

Previous GC identifers: GC22M016062 GC22M017495 GC22M017496 GC22M017500 GC22M002739


Summaries
for DGCR14 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for DGCR14:
This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a
group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal
anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with
microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous
protein in the mouse localizes to the nucleus. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DGC14_HUMAN, Q96DF8
Function: May be involved in pre-mRNA splicing

Gene Wiki entry for DGCR14


Genomic Views
for DGCR14 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.1  NT_011519.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DGCR14 gene promoter:
         NF-1/L   E47   Egr-4   CREB   Egr-2   PPAR-gamma1   deltaCREB   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DGCR14 promoter sequence
   Search SABiosciences Chromatin IP Primers for DGCR14

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DGCR14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.21|22q11.2   Ensembl cytogenetic band:  22q11.21   HGNC cytogenetic band: 22q11.21

DGCR14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DGCR14 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M019117:  view genomic region     (about GC identifiers)

Start:
 19,117,792 bp from pter      End:
 19,132,197 bp from pter
Size:
 14,406 bases      Orientation:
 minus strand

Proteins
for DGCR14 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DGC14_HUMAN, Q96DF8 (See protein sequence)
Recommended Name: Protein DGCR14  
Size: 476 amino acids; 52568 Da
Subunit: Identified in the spliceosome C complex
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q49AH7 Q9BTZ4

Explore the universe of human proteins at neXtProt for DGCR14: NX_Q96DF8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96DF8

    • DGCR14 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_073210.1  
    ENSEMBL proteins: 
     ENSP00000252137   ENSP00000388524  

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    Uscn Proteins for DGCR14

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS8703114
    GO:0071013catalytic step 2 spliceosome IDA11991638


    DGCR14 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for DGCR14 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DGCR14 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR019148 Nuclear_protein_DGCR14

    Graphical View of Domain Structure for InterPro Entry Q96DF8

    ProtoNet protein and cluster: Q96DF8

    UniProtKB/Swiss-Prot: DGC14_HUMAN, Q96DF8
    Similarity: Belongs to the DGCR14 family


    Function
    for DGCR14 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DGC14_HUMAN, Q96DF8
    Function: May be involved in pre-mRNA splicing

    miRNA
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    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate DGCR14 (see all 28):
    hsa-miR-34b* hsa-miR-562 hsa-miR-4286 hsa-miR-764 hsa-miR-888* hsa-miR-4275 hsa-miR-124 hsa-miR-2115
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--


    DGCR14 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for DGCR14:
     Decreased nuclei size in G2M  Synthetic lethal with Ras 

    Animal Models:
         Mouse knock-out Dgcr14tm1Bld for DGCR14
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Dgcr14):
     no phenotypic analysis 

    DGCR14 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for DGCR14 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DGCR14

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/25 Interacting proteins for DGCR14 (Q96DF82, 3 ENSP000002521374) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNB2L1P632442, 3, ENSP000003660134MINT-8338201 I2D: score=5 STRING: ENSP00000366013
    PFDN1O609252, 3MINT-8265772 I2D: score=2 
    VIMP086702, 3MINT-8277019 I2D: score=2 
    FRA10AC1Q70Z532, ENSP000003604884MINT-8331503 MINT-8338113 STRING: ENSP00000360488
    TTC14Q96N462, ENSP000002960154MINT-8338190 STRING: ENSP00000296015
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome IC11991638
    GO:0007399nervous system development ISS8703114


    DGCR14 for ontologies           About GeneDecksing



    Drugs & Compounds
    for DGCR14 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DGCR14
    Search CenterWatch for drugs/clinical trials and news about DGCR14 / DGC14 

    Transcripts
    for DGCR14 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DGCR14 gene: 
    NM_022719.2  

    Unigene Clusters for DGCR14:

    DiGeorge syndrome critical region gene 14
    Hs.517407  [show with all ESTs], Hs.741535
    Unigene Representative Sequences: NM_022719, BC037829
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000252137(uc002zou.3) ENST00000434568 ENST00000472073 ENST00000469466


    miRNA
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    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate DGCR14 (see all 28):
    hsa-miR-34b* hsa-miR-562 hsa-miR-4286 hsa-miR-764 hsa-miR-888* hsa-miR-4275 hsa-miR-124 hsa-miR-2115
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene shRNA RFP: DGCR14
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    Clone
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    Additional cDNA sequence: BC037829.1 

    24/25 DOTS entries (see all 25):

    DT.421881  DT.100640767  DT.95106644  DT.100719209  DT.113508  DT.101978026  DT.408872  DT.100776338 
    DT.100712321  DT.100823271  DT.120640067  DT.86852706  DT.100761005  DT.75152382  DT.95106642  DT.100653724 
    DT.100823266  DT.100823272  DT.100823273  DT.100823275  DT.100839564  DT.120639957  DT.95106647  DT.97810306 

    24/296 AceView cDNA sequences (see all 296):

    CA417227 CR602190 AL137713 BI755306 BU166399 BU180972 CR614835 CR615947 
    BX403453 CR617601 BX428458 CR595570 NM_022719 BX397099 BQ003566 L77566 
    CR602690 BE792561 AK095932 BI827554 L77565 BC003015 CB215858 CB121805 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for DGCR14 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b
    SP1:                          -     -                                               -                       -                     
    SP2:                          -     -                                                                                             
    SP3:                          -     -                                                                                             
    SP4:                                                                                                                              
    SP5:                                                                                            -           -                     


    ECgene alternative splicing isoforms for DGCR14

    Expression
    for DGCR14 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DGCR14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCGCCAGCCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    DGCR14 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeMetencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DGCR14 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DGCR14

    SOURCE GeneReport for Unigene clusters: Hs.517407 Hs.741535

    UniProtKB/Swiss-Prot: DGC14_HUMAN, Q96DF8
    Tissue specificity: Highly expressed in heart, brain and skeletal muscle. Detected at low levels in placenta

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    In Situ
    Assay Products:     
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    Orthologs
    for DGCR14 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DGCR14 gene from 9/26 species (see all 26)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Dgcr141 , 5 DiGeorge syndrome critical region gene 141, 5 86.27(n)1
    93.28(a)1    		   16 (11.09 cM)5
    278861  NM_022408.21  NP_071853.21 
     179007115 
    chicken
    (Gallus gallus)    		 Aves DGCR141 DiGeorge syndrome critical region gene 14 69.31(n)
    73.02(a)    		   416925  XM_415216.3  XP_415216.2 
    lizard
    (Anolis carolinensis)    		 Reptilia DGCR146
    		 --
    		 73(a)
    		 1 ↔ 1
    		 GL343282.1(742147-758138)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.157142 Xenopus laevis transcribed sequence with moderate similarity more 72.99(n)    BJ623526.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii dgcr141 DiGeorge syndrome critical region gene 14 66.51(n)
    69.04(a)    		   324123  NM_001089330.1  NP_001082799.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Es21 CG1474-PA 48.37(n)
    40.1(a)    		   31780  NM_132252.4  NP_572480.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea ess-21 Protein ESS-2 43.82(n)
    35.2(a)    		   176200  NM_001027409.2  NP_001022580.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT3G077901 protein DGCR14 43.35(n)
    31.49(a)    		   819970  NM_111658.3  NP_187436.1 
    rice
    (Oryza sativa)    		 Liliopsida Os06g05029001 hypothetical protein 46.23(n)
    34.62(a)    		   4341119  NM_001064246.1  NP_001057711.1 


    ENSEMBL Gene Tree for DGCR14 (if available)
    TreeFam Gene Tree for DGCR14 (if available) 

    Paralogs
    for DGCR14 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for DGCR14 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/338 NCBI SNPs in DGCR14 are shown (see all 338)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 22 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs81424861,2
    		C,F,A,H,--19117360(+) GCTTAG/AAGAAA 2 -- us2k1 ds50019Minor allele frequency- A:0.05NS EA NA WA 1208
    rs28009891,2
    		H--19117402(+) CCAGTC/TACTTT 2 -- ds5001 us2k14Minor allele frequency- T:0.00NS EA 416
    rs1449175411,2
    		--19117462(+) CTGCCA/GCCTCT 2 -- ds5001 us2k10--------
    rs1148552271,2
    		--19117682(+) GCACCA/GCTGCC 2 -- us2k1 ds50011Minor allele frequency- G:0.01WA 118
    rs1490270801,2
    		--19117820(+) TGTAAC/TTGGAT 2 -- ut31 us2k10--------
    rs1181406541,2
    		F,--19117843(+) CTGGAG/AATAAT 2 -- ut31 us2k11Minor allele frequency- A:0.03EA 120
    rs122333511,2
    		C,F,H,--19117892(+) GTTTAT/CATAGG 2 -- ut31 us2k112Minor allele frequency- C:0.07NS EA NA 1660
    rs791947981,2
    		C,F,--19117919(+) ACATGC/TAGTAC 2 -- us2k1 ut311Minor allele frequency- T:0.08EA 120
    rs1151888281,2
    		--19118002(+) AAGTCC/GGATTA 2 -- ut31 us2k11Minor allele frequency- G:0.01WA 118
    rs10567881,2
    		C--19118056(-) AAATAA/GTCACT 2 -- ut31 us2k11Minor allele frequency- G:0.00EA 178

    HapMap Linkage Disequilibrium report for DGCR14 (19117792 - 19132197 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for DGCR14
         1 CNV: 31071
         1 Indel: 46206
    Human Gene Mutation Database (HGMD): DGCR14

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    Disorders / Diseases
    for DGCR14 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DGCR14 for disorders           About GeneDecksing

    OMIM gene information: 601755    OMIM disorders: --

    5 diseases for DGCR14:    About MalaCards
    digeorge syndrome    velocardiofacial syndrome    conotruncal anomaly face syndrome    faces syndrome
    schizophrenia

    1 disease from the University of Copenhagen DISEASES database for DGCR14:
    DiGeorge syndrome

    1 Novoseek disease relationship for DGCR14 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    digeorge syndrome 86.1 1 9063747 (1)

    Human Genome Epidemiology (HuGE) Navigator: DGCR14 (5 documents)

    Export disorders for DGCR14 gene to outside databases

    Publications
    for DGCR14 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DGCR14 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with DGCR14)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Structural and mutational analysis of a conserved gene (DGSI) from the minimal DiGeorge syndrome critical region. (PubMed id 9063747)1, 2, 3, 9 Gong W....Budarf M.L. (1997)
    2. A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11. (PubMed id 8776594)1, 2, 3 Gong W.... Budarf M.L. (1996)
    3. Cloning and comparative mapping of a gene from the commonly deleted region of DiGeorge and Velocardiofacial syndromes conserved in C. elegans. (PubMed id 8703114)1, 2, 9 Rizzu P.... Baldini A. (1996)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
    6. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    7. A transcription map in the CATCH22 critical region: identification, mapping, and ordering of four novel transcripts expressed in heart. (PubMed id 8786095)1, 2 Lindsay E.A.... Baldini A. (1996)
    8. ES2, a gene deleted in DiGeorge syndrome, encodes a nuclear protein and is expressed during early mouse development, where it shares an expression domain with a Goosecoid-like gene. (PubMed id 9499415)1, 9 Lindsay E.A....Baldini A. (1998)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)

    External Searches for DGCR14 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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      Query String
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing DGCR14 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8220 HGNC: 16817 AceView: DGCR14 Ensembl:ENSG00000100056 euGenes: HUgn8220
    ECgene: DGCR14 H-InvDB: DGCR14

    Other Databases showing DGCR14 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing DGCR14 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DGCR14 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for DGCR14 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for DGCR14 gene:
    Search GeneIP for patents involving DGCR14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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